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  1. 441
  2. 442

    Leptomeningeal Contrast Enhancement Is Associated with Disability Progression and Grey Matter Atrophy in Multiple Sclerosis by Gleb Makshakov, Evgeniy Magonov, Natalia Totolyan, Vladimir Nazarov, Sergey Lapin, Alexandra Mazing, Elena Verbitskaya, Tatiana Trofimova, Vladimir Krasnov, Maria Shumilina, Alexander Skoromets, Evgeniy Evdoshenko

    Published 2017-01-01
    “…Leptomeningeal contrast enhancement (LMCE) on magnetic resonance imaging (MRI) is a newly recognized possible biomarker in multiple sclerosis (MS), associated with MS progression and cortical atrophy. In this study, we aimed to assess the prevalence of LMCE foci and their impact on neurodegeneration and disability. …”
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  3. 443

    Tubular basement membrane amyloid deposition: is it an indicator of renal progression in light chain amyloidosis? by Csilla Markóth, László Bidiga, László Váróczy, Ibolya File, József Balla, János Mátyus

    Published 2023-12-01
    “…These findings indicate the importance of TBM amyloid deposition in the progression of renal disease. This may represent a late-stage presentation of the disease with a heavy LC burden.…”
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  4. 444

    Strategies to investigate and mitigate collider bias in genetic and Mendelian randomisation studies of disease progression. by Ruth E Mitchell, April E Hartley, Venexia M Walker, Apostolos Gkatzionis, James Yarmolinsky, Joshua A Bell, Amanda H W Chong, Lavinia Paternoster, Kate Tilling, George Davey Smith

    Published 2023-02-01
    “…In this paper, our aim is to review several statistical methods that can be used to detect and adjust for index event bias in studies of disease progression, and how they apply to genetic and MR studies using both individual- and summary-level data. …”
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  5. 445

    Comorbid Neurodegeneration in Primary Progressive Aphasia: Clinicopathological Correlations in a Single-Center Study by Robert Rusina, Radoslava Bajtosova, Zsolt Cséfalvay, Jiri Keller, Anna Kavkova, Jaromír Kukal, Radoslav Matej

    Published 2022-01-01
    “…Introduction. Primary progressive aphasia (PPA) is a clinically variable syndrome manifesting as slow progressive loss of speech and language with multiple underlying neurodegenerative pathologies. …”
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  6. 446

    Myosin 1b Inhibits the Phenotype of HemECs to Affect the Progression of Infantile Hemangiomas by Li N, Gong X, Cao Z, Li Z, Wang L, Huo R, Fu C

    Published 2025-04-01
    “…Expression of Myo1b in hemangioma endothelial cells (HemECs) was detected using quantitative real-time polymerase chain reaction and Western blotting techniques. …”
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  7. 447

    MACL-1 Breast Cancer Secretome Reprograms Fibroblasts to Enhance Inflammation and Tumor Progression by RODRIGO JUNIO R. BARROS, ANDREIA LAURA P. RODRIGUES, CAMILA DOURADO, LUCIANA MARIA SILVA, JONAS ENRIQUE A. PERALES, SANDRA LAUTON-SANTOS, ANDREIA BARROSO, JADER S. CRUZ

    Published 2025-08-01
    “…Abstract Tumor-secreted factors reprogram the stromal microenvironment to facilitate cancer progression. This study investigates the effects of the MACL-1 breast cancer cell secretome on CCD19-Lu fibroblasts. …”
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  8. 448

    The Potential Mechanism of D-Amino Acids – Mitochondria Axis in the Progression of Diabetic Kidney Disease by Hoang Thuy Linh, Yusuke Nakade, Takashi Wada, Yasunori Iwata

    Published 2025-02-01
    “…There is increasing evidence that mitochondrial dysfunction, including impaired mitochondrial biogenesis, dynamics, and oxidative stress, contributes to the development and progression of DKD. D-amino acids (D-AAs), which are enantiomers of L-AAs, have recently been detected in various living organisms and are acknowledged to play important roles in numerous physiological processes in the human body. …”
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  9. 449
  10. 450

    PFKM phosphorylates histone H3 and promotes mitotic progression by sensing the levels of citrate by Pianpian Lin, Yijun Qi, Huiying Chu, Hongyu Wu, Yajuan Zhang, Xiaolan Huang, Chen Li, Xiaoyan Xu, Hong Gao, Rong Zeng, Guohui Li, Weiwei Yang

    Published 2025-07-01
    “…Citrate, a key intermediate in the TCA cycle, peaks during mitosis (M phase) and is detected by the glycolytic enzyme ATP-dependent 6-phosphofructokinase 1 muscle isoform (PFKM), accelerating mitotic progression. …”
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  11. 451
  12. 452

    Photoacoustic Imaging in Inflammatory Orthopedic Diseases: Progress toward Precise Diagnostics and Predictive Regulation by Mengyi Huang, Haoyu Yu, Rongyao Gao, Yuxin Liu, Xuhui Zhou, Limin Fu, Jing Zhou, Luoyuan Li

    Published 2025-04-01
    “…It covers the types of PA nanoprobes and their research progress in orthopedic inflammation, as well as the potential applications of PAI in various aspects. …”
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  13. 453

    Evaluating progress in achieving the SDGs at sub-national level in Spain: a multicriteria analysis by Luisa Paolotti, Ignacio Melendez Pastor, Elena Ricciolini, Lucia Rocchi, Asunción Maria Agulló Torres, Antonio Boggia

    Published 2025-08-01
    “…Focusing on the implementation effort and monitoring the progress of SDGs are crucial aspects for achieving the Goals by 2030. …”
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  14. 454

    Myopia Progression Risk: Seasonal and Lifestyle Variations in Axial Length Growth in Czech Children by Stepan Rusnak, Vaclav Salcman, Lenka Hecova, Zdenek Kasl

    Published 2018-01-01
    “…The growth in the prevalence of myopia leads to the growth of socioeconomic stress in society. It is important to detect any potential risk factors leading to myopia onset and progression. …”
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    Sinusoidal Endothelial Cell Progenitor Cells Promote Tumour Progression in Patients with Hepatocellular Carcinoma by Ya-xing Feng, Wei Li, Xu-dong Wen, Ning Zhang, Wei-hui Liu, Zhan-yu Yang

    Published 2020-01-01
    “…As sinusoidal endothelial cell progenitor cells (SEPCs) play a significant role in liver regeneration, it is necessary to elucidate whether SEPCs participate in tumour progression of hepatocellular carcinoma (HCC). Methods. …”
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    In vivo MRI characterization of progressive cardiac dysfunction in the mdx mouse model of muscular dystrophy. by Daniel J Stuckey, Carolyn A Carr, Patrizia Camelliti, Damian J Tyler, Kay E Davies, Kieran Clarke

    Published 2012-01-01
    “…Here we employed a comprehensive array of clinically relevant in vivo MRI techniques to identify early markers of cardiac dysfunction and follow disease progression in the hearts of mdx mice.<h4>Methods and results</h4>Serial measurements of cardiac morphology and function were made in the same group of mdx mice and controls (housed in a non-SPF facility) using MRI at 1, 3, 6, 9 and 12 months after birth. …”
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  20. 460

    PRDX6 Drives Breast Cancer Progression Through Mitochondrial Biosynthesis and Oxidative Phosphorylation by Mei Dai, Danhua Zhang

    Published 2025-07-01
    “…Mitochondria were visualized by TEM, and mitochondrial complex subunits were detected by quantitative real‐time PCR and Western blotting. …”
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