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  1. 361

    The role of RNA methylation in glioma progression: mechanisms, diagnostic implications, and therapeutic value by Shao-Ze Zhang, Shao-Ze Zhang, Shao-Ze Zhang, Shao-Yan Liu, Meng-Die Cheng, Yin-Feng Zhang, Jia-Wei Tian

    Published 2025-05-01
    “…Glioma represents a highly lethal form of malignant tumour, with RNA methylation emerging as a critical regulator of its oncogenesis and progression. As a prevalent post-translational modification, methylation influences various biological functions, particularly RNA processing, by modulating splicing, transport, and degradation of both mRNAs and noncoding RNAs. …”
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    Large language model trained on clinical oncology data predicts cancer progression by Menglei Zhu, Hui Lin, Jue Jiang, Abbas J. Jinia, Justin Jee, Karl Pichotta, Michele Waters, Doori Rose, Nikolaus Schultz, Sulov Chalise, Lohit Valleru, Olivier Morin, Jean Moran, Joseph O. Deasy, Shirin Pilai, Chelsea Nichols, Gregory Riely, Lior Z. Braunstein, Anyi Li

    Published 2025-07-01
    “…On UCSF data, it achieved an overall AUROC of 0.88, excelling in lung cancer detection with an AUROC of 0.95. As the first oncology specific LLM validated across institutions, Woollie demonstrates high accuracy and consistency across cancer types, underscoring its potential to enhance cancer progression analysis.…”
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  4. 364

    Recent Progress in Intrinsically Stretchable Sensors Based on Organic Field-Effect Transistors by Mingxin Zhang, Mengfan Zhou, Jing Sun, Yanhong Tong, Xiaoli Zhao, Qingxin Tang, Yichun Liu

    Published 2025-02-01
    “…Intrinsically stretchable sensors have been widely applied in smart wearables, electronic skin, biological detection, and environmental protection. In this review, we summarize the recent progress in intrinsically stretchable sensors based on OFETs, including advancements in functional layer materials, sensing mechanisms, and applications such as gas sensors, strain sensors, stress sensors, proximity sensors, and temperature sensors. …”
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    Optical Coherence Tomography as a Biomarker for Diagnosis, Progression, and Prognosis of Neurodegenerative Diseases by Maria Satue, Javier Obis, Maria J. Rodrigo, Sofia Otin, Maria I. Fuertes, Elisa Vilades, Hector Gracia, Jose R. Ara, Raquel Alarcia, Vicente Polo, Jose M. Larrosa, Luis E. Pablo, Elena Garcia-Martin

    Published 2016-01-01
    “…Retinal thinning has been observed in these patients and new segmentation software for the analysis of the different retinal layers may provide accurate information on disease progression and prognosis. In this review we analyze the application of retinal evaluation using OCT technology to provide better understanding of the possible role of the retinal layers thickness as biomarker for the detection of these neurodegenerative pathologies. …”
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    The role of neuroimaging in Alzheimer’s disease: implications for the diagnosis, monitoring disease progression, and treatment by Julius Mulumba, Rui Duan, Bo Luo, Jiang Wu, Muhammad Sulaiman, Feng Wang, Yong Yang

    Published 2025-02-01
    “…Neuroimaging enables the visualization of Alzheimer-related biomarkers, such as Aβ plaques, tau protein tangles, neuro-inflammation, and synaptic dysfunction, providing valuable insights into disease pathophysiology and progression. These imaging techniques assist in the early detection of AD, distinguishing it from other conditions and evaluating the effectiveness of treatments. …”
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    Recent progress in tuberculosis diagnosis: insights into blood-based biomarkers and emerging technologies by Zewei Yang, Jingjing Li, Jiawen Shen, Huiru Cao, Yuhan Wang, Sensen Hu, Yulu Du, Yange Wang, Zhongyi Yan, Longxiang Xie, Qiming Li, Salwa E. Gomaa, Salwa E. Gomaa, Shejuan Liu, Shejuan Liu, Xianghui Li, Jicheng Li, Jicheng Li

    Published 2025-05-01
    “…Recent advancements in the field of TB diagnostics have focused on the identification and utilization of blood-based biomarkers, offering a non-invasive, rapid, and scalable approach to disease detection. This review provides a comprehensive overview of the latest progress in blood-based biomarkers for TB, highlighting their potential to revolutionize diagnostic strategies. …”
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    The association of plasma NT-proBNP level and progression of diabetic kidney disease by Yuancheng Zhao, Lijun Zhao, Yiting Wang, Junlin Zhang, Honghong Ren, Rui Zhang, Yucheng Wu, Yutong Zou, Nanwei Tong, Fang Liu

    Published 2023-12-01
    “…The identification of risk factors involved in the progression of DKD to ESKD is expected to result in early detection and appropriate intervention and improve prognosis. …”
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  14. 374

    Total Bilirubin Predicts Severe Progression of Diabetic Retinopathy and the Possible Causal Mechanism by Yu Ding, Junmin Zhao, Gangsheng Liu, Yinglong Li, Jiang Jiang, Yun Meng, Tingting Xu, Kaifeng Wu

    Published 2020-01-01
    “…Early detection and treatment are key to delaying the progression of diabetic retinopathy (DR), avoiding loss of vision, and reducing the burden of advanced disease. …”
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  15. 375

    Implications of high throughput sequencing of plant viruses in biosecurity – a decade of progress? by Fox, Adrian, Botermans, Marleen, Ziebell, Heiko, Fowkes, Aimee R., Fontdevila Pareta, Nuria, Massart, Sebastien, Rodoni, Brendan, Chooi , Kar Mun, Kreuze, Jan, Kumar, P. Lava, Cuellar, Wilmer J., Carvajal-Yepes, Monica, MacDiarmid , Robin M.

    Published 2025-07-01
    “…In the 15 years since High Throughput Sequencing (HTS) was first used for the detection and identification of plant viruses, the technology has matured and is now being used in frontline plant biosecurity applications. …”
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  16. 376

    Research Progress and Prospect of Multi-robot Collaborative SLAM in Complex Agricultural Scenarios by MA Nan, CAO Shanshan, BAI Tao, KONG Fantao, SUN Wei

    Published 2024-11-01
    “…To unlock the full potential of multi-robot SLAM in agriculture, it is essential to develop optimized solutions that address the specific technical demands of these scenarios.[Progress]Existing review studies on multi-robot SLAM mainly focus on a general technological perspective, summarizing trends in the development of multi-robot SLAM, the advantages and limitations of algorithms, universally applicable conditions, and core issues of key technologies. …”
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  17. 377

    Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression by Tingting Xu, Jianmin Huang, Jiajing Lin, Yuanyuan Liu, Yi Wang, Wenkang Shen, Jianjie He, Shuyun Chen, Xi Zhu, Yuqin Que, Mengting Hu, Yu Chen, Liming Cheng, Honghao He, Xin Liu, Si Liu

    Published 2025-02-01
    “…Conclusions Alterations in subclass-specific IgG N-glycosylation represent promising biomarkers for the detection and monitoring of GC progression, potentially influenced by cytokine-driven inflammation. …”
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