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  1. 981

    Tumor-derived immunoglobulin-like transcript 3 inhibition reshapes the immunosuppressive tumor microenvironment and potentiates programmed cell death ligand 1 blockade immunotherap... by Leirong Wang, Qing Li, Yanxin Sun, Shuyun Wang, Xuebing Fu, Xiufen Wang, Yan Zheng, Aiqin Gao, Yuping Sun, Juan Li

    Published 2025-06-01
    “…Furthermore, combined inhibition of gp49b and programmed cell death ligand 1 (PD-L1) showed the most drastic tumor regression in C57BL/6 mice models.Tumor-derived ILT3 overexpression suppresses anti-tumor immunity by recruiting M2-like TAMs and impairing T cell activities, while ILT3 inhibition counteracts this immunosuppression and enhances the efficacy of PD-L1 blockade in LUAD. …”
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    SEMIOTICS, DIAGNOSTICS AND THERAPY TACTICS OF DEPRESSIVE DISORDERS IN CLINICAL MEDICINE by N. A. Kornetov

    Published 2014-06-01
    “…There, about 1450 doctors of different occupations were acquainted with the detection, management and treatment of MDD. The Russian version of WPA/PTD programs was created. …”
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  4. 984

    NEW APPROACHES TO THE ORGANIZATION OF SKIN CANCER SCREENING by A. A. Modestov, E. V. Semjonov, R. A. Zukov, E. V. Slepov, E. N. Eremina, E. N. Gaas

    Published 2017-06-01
    “…Despite the high incidence rate of skin cancer, there is no single standard for screening to identify this disease at an early stage, therefore, screening programs for detecting premalignant lesions and skin cancer at early stages are of great importance. …”
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    Exploring Life Detection on Mars: Understanding Challenges in DNA Amplification in Martian Regolith Analogue After Fe Ion Irradiation by Alessia Cassaro, Claudia Pacelli, Silvano Onofri

    Published 2025-04-01
    “…PCR-based amplification methods were used for detection. The findings of this study revealed no DNA amplification in samples mixed with Sulfatic Mars Regolith Simulant, providing important insights into the potential application of these techniques for in situ DNA detection during future space exploration missions or for their application on the Mars sample return program; it also gives input in the planetary protection discussions.…”
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  18. 998

    Architecture of an integrated java application for log analysis to detect computer attacks in information systems by responding to various security anomalies by P. I. Sharikov, A. V. Krasov, A. V. Mayorovv

    Published 2025-04-01
    “…The research used methods of analyzing information in information system logs, static analysis methods, programming for application development, and data processing algorithms.Result. …”
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