PF-06447475 Molecule Attenuates the Neuropathology of Familial Alzheimer’s and Coexistent Parkinson’s Disease Markers in PSEN1 I416T Dopaminergic-like Neurons by Diana Alejandra Quintero-Espinosa, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio

“…Notably, these DALNs exhibited PD-associated proteins such as intracellular accumulation of α-Syn (detected as aggregates of pS129-α-Syn) and phosphorylation of LRRK2 kinase at residue S935. …”
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THE FEATURES OF SURGICAL TREATMENT AND MORPHOLOGICAL ASPECTS OF EPULIS AND PAPILLOMA IN CHILDREN by P.I. Tkachenko, I.I. Starchenko, S.O. Bilokon, N.M. Lokhmatova, O.B. Dolenko, N.M. Korotych, Yu.V. Popelo, N.P. Bilokon

“…Verification of the histological structure of neoplasms to determine the final diagnosis was performed by the faculty staff of the Department of Pathological Anatomy with Autopsy Course. Statistical processing of the digital data and analysis of the findings of the study showed that epulis and papillomas are more common in girls than in boys (in 2.5 and 2.3 times higher, respectively). …”
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Electrical properties of the myocardium in patients with arterial hypertension combined with subclinical hypothyroidism by V. V. Syvolap, Ye. V. Novikov

“…A 40 Hz cutoff filter was used recording in the X, Y, Z orthogonal leads. Data were processed with the help of a program Statistica 6.0. …”
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Vitamin D status in children with nasopharyngeal manifestations of gastroesophageal reflux disease by L. V. Hrebeniuk

“…The results were statistically processed by means of Microsoft Office Excel and Statistica 13 software. …”
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DEPENDENCE OF CHANGES IN THE HYGIENIC CONDITION OF THE ORAL CAVITY AND PERIODONTIUM IN CHILDREN WITH MALIGNANT TUMORS ON THE DURATION OF POLYCHEMYTHERAPY AND QUANTITIES OF CYTOSTAT... by Yu.V. Popelo

“…The calculation was per- formed in 10 visual fields. Statistical processing was performed according to standard conditions. …”
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Periaural Music Player Daily Use Does Not Significantly Influence the Hearing Thresholds by Saralidze N., Sharashenidze N., Tushishvili M., Kevanishvili Z.

“…The obtained results were processed quantitively using the program IMB SPSS Statistics 20. …”
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Material Characterization and Technological Properties of Biocompatible Ti-12Al-42Nb Spherical Powder Alloy for Additive Manufacturing of Personal Medical Implants by Alexander Anokhin, Andrey Kirsankin, Elena Kukueva, Alexander Luk’yanov, Maria Chuvikina, Elena Ermakova, Svetlana Strelnikova, Stepan Kupreenko

“…Image J software was used to calculate the spherical degree by processing images sets from scanning electron microscopy (SEM) and optical microscopy (OM). …”
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Application of machine learning in early childhood development research: a scoping review by Akbar K Waljee, Amina Abubakar, Patrick N Mwangala, Faith Neema Benson, Daisy Chelangat, Willie Brink, Cheryl A Moyer

“…No publication date limits were applied.Eligibility criteria Included studies applied ML or its variants (eg, deep learning (DL), natural language processing) to developmental outcomes in children aged 0–8 years. …”
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Preliminary study on the mechanism of Huangqi Decoction in treating slow transit constipation by Chen Huaxian, Yang Chaoxin, Xiao Guozhong, Zheng Yihui, Lei Mingyuan, Lin Hongcheng

“…The results of GO functional enrichment analysis showed that intersection genes were mainly concentrated in biological processes (BP) such as response to molecule of bacterial origin, regulation of inflammatory response, and positive regulation of cytokine production, molecular functions (MF) such as cytokine receptor binding and cytokine activity, and cell components (CC) such as membrane raft and membrane microdomain. …”
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Immune analysis according to Lauren type for gastric cancer and its significance in individual treatment and prognostic prediction by Huiwen Lu, Junqiao Yao, Junqiao Yao, Chi Xue, Chi Xue, Rui Huang, Rui Huang, Baojun Huang, Baojun Huang

“…Tumor specimens were collected and processed with immunohistochemical staining to detect the difference in immune marker expression between Lauren types. …”
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Analysis of microRNA expression reveals convergent evolution of the molecular control of diapause in annual killifishes by Emanuel Barth, Emanuel Barth, Mario Baumgart, Luca Dolfi, Rongfeng Cui, Marco Groth, Roberto Ripa, Aurora Savino, Dario Riccardo Valenzano, Dario Riccardo Valenzano, Matthias Platzer, Manja Marz, Alessandro Cellerino, Alessandro Cellerino

“…We found several microRNAs that showed convergent regulation in the three different clades, and for some microRNAs also a phenomenon of switch in the prevalent form between 3p and 5p or vice versa was noted. In addition, we detected a significant overlap between the microRNA regulation during diapause and aging. …”
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Co-occurrence and importance of AmpC and extended-spectrum beta-lactamases-producing gram-negative bacilli in clinical specimens at a Tertiary Hospital in Dar es Salaam, Tanzania by Japhet Anania Peter, Salim Masoud, Doreen Kamori, Agricola Joachim, Upendo Kibwana, Joel Manyahi, Mtebe Majigo, Mecky Matee

“…Methods We conducted a laboratory-based cross-sectional study involving routinely processed clinical isolates. The Analytical Profile Index-20 test (API20E) was used to identify isolates to species level. …”
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Mechanism study of KCMF1 promoting proliferation and NF-κB signaling transduction in colorectal cancer cells by WU Zhibai, XU Guiqin, ZHANG Li, YANG Zhaojuan, LIU Yun, JIAO Kun, CHEN Zehong, XU Chen, ZUO You, ZHENG Ningqian, YE Zhiqian, LIU Yongzhong

“…It binds to target proteins through the RING domain and participates in the regulation of a variety of biological processes in vivo. However, the function of KCMF1 in CRC remains unclear. …”
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Retrospective Analysis of the Pattern, Causes and Variants of Ocular Herpes Severity by G. M. Chernakova, G. Sh. Arzhimatova, E. V. Shirshova, A. V. Andrianova, E. A. Kleshcheva, N. V. Mel’nikova

“…The most frequent (422 cases) provoked ophthalmic herpes was different systemic infectious processes. The second place by the frequency of provoking factors is occupied by a group of causes related to corneal damage of different genesis (285 patients). …”
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The variations of wheat–maize production, soil organic carbon, and carbon footprints: insights from a 20–year on–farm observational experiment in the North China Plain by Ning Wang, Ning Wang, Zhipin Ai, Zhipin Ai, Zhipin Ai, Qiuying Zhang, Peifang Leng, Peifang Leng, Peifang Leng, Yunfeng Qiao, Yunfeng Qiao, Yunfeng Qiao, Zhao Li, Zhao Li, Zhao Li, Chao Tian, Chao Tian, Xinjie Shi, Hefa Cheng, Gang Chen, Fadong Li, Fadong Li, Fadong Li

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Insight-HXMT Observations of the Extremely Bright GRB 221009A by Wen-Long Zhang, Wang-Chen Xue, Cheng-Kui Li, Shao-Lin Xiong, Gang Li, Yong Chen, Wei-Wei Cui, Xiao-Bo Li, Cong-Zhan Liu, Ming-Yu Ge, Wen-Jun Tan, Jia-Cong Liu, Chen-Wei Wang, Chao Zheng, Yan-Qiu Zhang, Yue Wang, Zhen Zhang, Shu-Xu Yi, Shuo Xiao, Ce Cai, Shuang-Xi Yi, Li-Ming Song, Lian Tao, Shu Zhang, Shuang-Nan Zhang

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Characterization of full-length long noncoding RNAs and identification of virus-responsive lncRNAs in Sogatella furcifera by Yawen Ban, Yawen Ban, Ting Cui, Ting Cui, Lifei Zhao, Lifei Zhao, Xue Li, Xue Li, Qing Bai, Qing Bai, Qingfa Wu, Qingfa Wu

“…Functional enrichment analysis linked male-biased lncRNAs to metabolic pathways and molting-associated lncRNAs to tissue remodeling processes, including Wnt signaling. Upon SRBSDV infection, approximately 50% of differentially expressed lncRNAs responded to both virus exposure (feeding on infected plants) and confirmed viral replication, exhibiting distinct sex-dimorphic regulation. …”
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A novel mechanism of FTO modulating the progression of endometriosis through mediating the m6A methylation of GEF-H1 in a YTHDF1-dependent manner by Xin-Yu Ding, Hua-Ying Zhang, Jia-Hao Chen, Meng-Jie Yang, Zhi-Xiong Huang, Yi-Hong Lei, Qin-Kun Sun, Jian-Bin Bai, Dian-Chao Lin, Jian-Fa Lan, Lu-Lu Ren, Zheng-Yi Chen, Wei-Dong Zhou, Qiong-Hua Chen

“…N6-methyladenosine (m6A) is a common RNA modification involved in diverse biological processes, but its role in EMs remains unclear. Methods A human endometrial stromal cell line (HESCs), primary eutopic endometrial stromal cells (Eu-ESCs), primary ectopic endometrial stromal cells (Ec-ESCs), and clinical samples were used in this study. …”
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Correlation of excess salt intake identified by the survey with urine sodium level and blood pressure: data of ESSE-RF study by Yu. A. Balanova, V. A. Kutsenko, S. A. Shalnova, A. E. Imaev, A. V. Kapustina, G. A. Muromtseva, S. E. Evstifeeva, N. S. Karamnova, S. A. Maksimov, E. B. Yarovaya, O. M. Drapkina, A. N. Redko, S. N. Alekseenko, S. V. Gubarev, I. A. Viktorova, M. A. Livzan, I. A. Grishechkina, M. Yu. Rozhkova, N. N. Prishchepa, N. N. Vezikova, I. S. Skopets, S. S. Yakushin, E. V. Filippov, N. V. Dobrynina, N. N. Nikulina, K. G. Pereverzeva, K. A. Moseichuk

“…In the pattern of ESI components, processed meat and sausage products take first place in terms of association strength with urine sodium. …”
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Expert consensus on the evaluation and management of high-risk indeterminate pulmonary nodules by Yang Dawei, Stephan Lam, Kai Wang, Zhou Jian, Zhang Xiaoju, Wang Qi, Zhou Chengzhi, Zhang Lichuan, Bai Li, Wang Yuehong, Li Ming, Sun Jiayuan, Li Yang, Fengming Kong, Haiquan Chen, Ming Fan, Xuan Jianwei, Fred R. Hirsch, Charles A. Powell, Bai Chunxue

“…Artificial intelligence (AI) assessment based on the Medical Internet of Things (MIoT) can be combined with expert opinion to form a human–computer multidisciplinary team (MDT) that can fully implement the three core procedures of the MIoT, namely, comprehensive perception, reliable transmission, and intelligent processing. This will help to upgrade the non-standard diagnosis and treatment, the so-called “handicraft workshop model”, to a modern assembly-line model that meets international standards. …”
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