cGAS-STING Targeting Offers Novel Therapeutic Opportunities in Liver Diseases by Wang Y, Yang R, Cao Y, Li Y, Zhu Y, Zhang Z, Fleishman JS, Chen J, Ding M

“…John’s University, Queens, NY, 11439, USA, Email joshua.fleishman18@my.stjohns.eduAbstract: Cyclic GMP/AMP (cGAMP) synthase (cGAS), coupled with the endoplasmic reticulum (ER)-anchored adaptor protein stimulator of interferon genes (STING), constitute key components of the type 1 interferon signaling network. cGAS detects both pathogen-derived DNA and aberrant cytosolic self-DNA, establishing the cGAS-STING pathway as a central player in autoimmune disorders, sterile inflammation, and senescence-related processes. …”
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Changes and Correlation Between Hormones, Immunoglobulins, and Minerals in Blood Serum and Hair of Tianzhu White Yaks of Different Ages and Gender by Yunqi Deng, Bingang Shi, Youpeng Qi, Zhihao Luo, Changze Cui, Shaopeng Chen, Xuelan Zhou, Zhidong Zhao, Xiaolan Zhang, Jiang Hu

“…It is likely that they jointly regulate the hair growth and immune processes of yaks. (4) Conclusions: There are positive correlations among melatonin, dihydrotestosterone, and IgA in the blood serum and the content of Fe and Mg in the hair to varying degrees, implying these indicators may jointly regulate yak hair growth and immune status. …”
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COP1 drives renal cell carcinoma progression by targeting ACSL4 for ubiquitin-mediated degradation and inhibiting ferroptosis by Yuxiao Zheng, Lei Jiang, Feng Qi, Bo Peng

“…BackgroundRenal cell carcinoma (RCC) progression is closely linked to dysregulation of the ubiquitin-proteasome system, particularly aberrant ubiquitination processes governing protein degradation and cell cycle control. …”
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Pengenalan Aktivitas Manusia Menggunakan Sensor Akselerometer dan Giroskop pada Smatphone dengan Metode K-Nearest Neighbor by Zainal Arifien, Fitra Abdurrahman Bachtiar, Novanto Yudistira

“…The data obtained consists of 3 axes (x, y, and z) on each sensor used. The data then processed and classified using the k-Nearest Neighbor (k-NN) algorithm. …”
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POSITION OF THE TEMPOROMANDIBULAR JOINT DYSFUNCTION SYNDROME AMONG FACIAL PAIN SYNDROMES by V.L. Melnyk, V.K. Shevchenko, Yu.I. Sylenko

“…The pathology of TMJ dysfunction was detected in 80% of the examined patients (Bezrukov V.M, 2002). …”
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AN INFLUENCE OF SPONTANEOUS MICROFLORA OF FERMENTED HORSEMEAT PRODUCTS ON THE FORMATION OF BIOLOGICALLY ACTIVE PEPTIDES by I. M. Chernukha, I. N. Nikonov, N. G. Mashentseva, D. L. Klabukova, D. A. Afanasev, L. I. Kovalyov, L. А. Ilina

“…It is necessary to note that about 25 % of microflora was unculturable; i.e., it had metabolic processes but did not grow on culture media. In the samples, the representatives of Actinobacteria and Pseudomonadales were found. …”
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Probing Equatorial Ionospheric TEC at Sub-GHz Frequencies with Wide-Band (B4) uGMRT Interferometric Data by Dipanjan Banerjee, Abhik Ghosh, Sushanta K. Mondal, Parimal Ghosh

“…Radio interferometers such as the giant metrewave radio telescope (GMRT) are capable of detecting changes in the ionosphere’s total electron content (TEC) over larger spatial scales and with greater sensitivity compared to conventional tools like the global navigation satellite system (GNSS). …”
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Design, Dynamics and Development of Upgraded Tiltable Wing associated Quadcopter through Advanced computational simulations incorporated Bottom-Up Approach by Haribalan Saravana Mohan, Karthikeyan Murugaraj, Senthil Kumar Solaiappan, Beena Stanislaus Arputharaj, Parvathy Rajendran, It Ee Lee, Shyam Sundar Jayakumar, Janani Priyadharshini Veeraperumal Senthil Nathan, Arunkumar Karuppasamy, Vijayanandh Raja

“…Abstract This paper aims to design a hybrid quadcopter that can be used for multiple detecting applications in which its performance parameters are studied under various maneuverings such as forward and vertical movements based on computational studies. …”
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The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis by Yan Zhang, Yan Zhang, Xueju Wang, Xuefeng Wang, Gengdi Huang

“…These regions are involved in altered pain processing, including nociceptive stimulus integration, subjective pain perception, pain chronification, and pain-related empathy. …”
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The gut microbiota and diabetic nephropathy: an observational study review and bidirectional Mendelian randomization study by Yi Zhen Han, Yang Zhi Yuan Wang, Xing Yu Zhu, Bo Xuan Du, Yao Xian Wang, Xue Qin Zhang, Jia Meng Jia, Wei Jing Liu, Hui Juan Zheng

“…Abstract Background Earlier studies have implicated a crucial link between diabetic nephropathy (DN) and the gut microbiota (GM) by considering the gut-kidney axis; however, the specific cause-and-effect connections between these processes remain unclear. Methods To compare changes in the GM between DN patients and control subjects, a review of observational studies was performed. …”
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A novel lightweight 3D CNN for accurate deformation time series retrieval in MT-InSAR by Mahmoud Abdallah, Xiaoli Ding, Samaa Younis, Songbo Wu

“…Multi-temporal interferometric synthetic aperture radar (MT-InSAR) is a powerful geodetic technique for detecting and monitoring ground deformation over extensive areas. …”
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Impact of Symptomatic COVID-19 on the Oral Health of Pediatric Patients in Tbilisi City by Lia Mania, Ketevan Nanobashvili, Tinatin Manjavidze, Mamuka Benashvili, Nino Bzishvili, Ia Astamadze

“…Logistic regression was used to calculate ORs with 95% confidence intervals. The statistical processing of the data was performed with SPSS 23.0. …”
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Epitranscriptomic Analysis of the Ventral Hippocampus in a Mouse Model of Post-Traumatic Stress Disorder Following Deep Brain Stimulation Treatment of the Basolateral Amygdala by Mingxi Ma, Hao Fan, Hui Zhang, Yao Yin, Yizheng Wang, Yan Gao

“…The hippocampus, a brain region closely connected to the amygdala, plays a key role in the pathological processes of PTSD. The N6-methyladenosine (m⁶A) methylation of RNAs in the hippocampus is known to play a significant role in regulating the brain’s response to stress and emotional disorders. …”
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Association of Procalcitonin Level with the Severity of Pneumonia in Children under 5 Years of Age: A Prospective Cohort Study by P Ananya, SS Kalyanshettar, Trimal P Kulkarni, Mallanagouda M Patil

“…On admission, venous blood was drawn and processed for serum PCT. The data collected was entered into a Microsoft Excel spreadsheet and analysed using Statistical Package for the Social Sciences (SPSS), Version 20. …”
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Characteristics of soil microbial phospholipid fatty acids in artificial, black-soil mountain degraded, and natural grasslands in the source region of the Three Rivers by Lele Xie, Yushou Ma, Yanlong Wang, Yuan Ma, Xiaoli Wang, Ying Liu

“…Recent research on grassland restoration has increasingly focused on belowground processes, particularly the role of soil microbial communities in soil recovery. …”
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PSYCHOLOGICAL MECHANISMS OF FORMATION OF DEVIATIONS IN THE PERIOD OF PREPARATION FOR MOTHERHOOD by S. A. Moreva, A. V. Silaeva, A. N. Kornetov, Ye. N. Borodina, A. Ye. Yankovskaya, N. I. Pryadukhina, N. E. Golovakha, V. B. Obukhovskaya

“…Dobryakova (1996). Data processing was carried out using statistical methods Spearman rank correlation coefficient, nonparametric Mann–Whitney U and Kruskal–Wallis H and φ * – Fisher's angular transformation.Results. …”
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Keeping Active with Texting after Stroke (KATS): a single-arm feasibility and acceptability study of a behavioural intervention to promote community-based physical activity after s... by Gozde Ozakinci, Stephan U Dombrowski, Andrew Murphy, Albert Farre, Jenna Breckenridge, Jacqui H Morris, Linda A Irvine, Keith Jenkinson

“…Findings suggest some modifications of messages and goal-setting processes are required to accommodate participants with diverse physical activity capabilities before a definitive trial. …”
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Can machine-learning algorithms improve upon classical palaeoenvironmental reconstruction models? by P. Sun, P. B. Holden, H. J. B. Birks, H. J. B. Birks

“…We considered three versions of the model: (1) a standard version of MEMLM, which uses only taxon abundance data; (2) MEMLMe, which uses only dimensionally reduced assemblage information, using a natural language-processing model (GloVe), to detect associations between taxa across the training data set; and (3) MEMLMc which incorporates both raw taxon abundance and dimensionally reduced summary (GloVe) data. …”
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Evaluation of Pharmacokinetical Parameters of Phenol, a Component of Antiseptic Dorogov's stimulator 3 Fraction Paste by V. I. Nozdrin, G. A. Piavchenko, M. E. Ivanova, K. S. Guzev, S. L. Kuznetsov

“…Antiseptic Dorogov's stimulator 3rd fraction (ASD-3) is a multicomponent substance, which is obtained by the thermal processing of cattle-origin tissues, which contains more than 120 substances, including biologically active substances. …”
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Laser-wound stimulated adventitious root formation of Rosa canina cuttings involves a complex response at plant hormonal and metabolic level by Raul Javier Morales Orellana, Raul Javier Morales Orellana, Thomas Rath, Uwe Druege, Yudelsy A. Tandrón Moya, Nicolaus von Wirén, Traud Winkelmann

“…However, the biochemical processes involved in the response of rooting to the additional wounding remained unexplored.MethodsThe present study analyzed changes in the plant hormone and carbohydrate profiles in response to laser treatments of rose leafy single-node stem cuttings (Rosa canina ‘Pfänder’). …”
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