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20221
Ubiquitin specific peptidase 11 knockdown slows Huntington’s disease progression via regulating mitochondrial dysfunction and neuronal damage depending on PTEN-mediated AKT pathway...
Published 2025-01-01“…Ubiquitin specific peptidase 11 (USP11) is a deubiquitinating enzyme involved in various physiological processes through regulating protein degradation. However, its specific role in HD is unclear. …”
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20222
Variability of carotenoid synthesis and degradation genes in Russian durum wheat cultivars
Published 2025-06-01“…Yellow index is an important quality parameter of durum wheat cultivars, associated with carotenoid pigment content in grain and the level of carotenoid degradation during processing, and determining the yellow color of products made from durum wheat. …”
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20223
Farm-scale mapping of compost and digestate spreadings from Sentinel-2 and Sentinel-1
Published 2025-05-01“…Nevertheless, these image processing approaches considered one single EOM, one season and/or year only and were limited to one surface condition prior to spreading. …”
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20224
The association of HALP score with low muscle mass in older adults
Published 2025-08-01“…BackgroundThe HALP score, combining hemoglobin, albumin, lymphocyte, and platelet parameters, serves as a comprehensive indicator reflecting both inflammatory processes and nutritional conditions. Our investigation aimed to explore the association of this composite score with the prevalence of low muscle mass and associated mortality in the elderly American population.MethodsThe investigation incorporated information from 3,550 individuals aged ≥60 years enrolled in the National Health and Nutrition Examination Survey (NHANES) between 1999 and 2004. …”
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20225
DIFFERENTIAL AND DIAGNOSTIC CRITERIA OF THE RECURRENCE OF GLIOMAS IN THE POST-OPERATIONAL PERIOD USING OF DYNAMIC CONTRAST-ENHANCED MRA AND PERFUSION MRI
Published 2018-03-01“…Relative Cerebral Blood Volumes (rCBV) were estimated on the contrast-enhanced T1-weighted perfusion maps. Statistical processing of the results was performed using ROC analysis.Results. …”
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20226
Microplastics in municipal water: analysing variations in contamination in a Lowveld city, South Africa
Published 2025-08-01“…These findings indicate the need for further evaluation of the water treatment processes and the importance of routine faucet aerator maintenance to minimise household microplastic exposure. …”
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20227
Use of liver steatosis and fibrosis indices in overweight and obese patients with or without carbohydrate metabolism disorders
Published 2025-05-01“…The steatosis index FLI and fibrosis indices FIB-4, APRI, BARD, and NFS were calculated. Statistical processing of the results included comparative analysis, frequency analysis, correlation — and ROC analysis.RESULTS: The study included 114 patients with overweight or obesity divided into groups depending on the CMD: group 1 — without CMD (n=52), group 2 — prediabetes (n=34), group 3 — newly diagnosed T2DM (n=28). …”
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20228
The use of artificial intelligence in the diagnosis of oral carcinoma
Published 2025-02-01“…Machine learning models effectively detect subtle anomalies and offer diagnostic performance that matches or surpasses expert clinical pathologists. …”
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20229
Unlocking the genetic secrets of Dorper sheep: insights into wool shedding and hair follicle development
Published 2024-12-01“…DETs with stage-specific expression had a significant presence in processes related to the hair cycle and skin development, and several classic signaling pathways involved in sheep HF development, such as Rap1, estrogen, PI3K-Akt, and MAPK, were detected. …”
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20230
Bioconvergence: advancing biosensors with nanotechnology for real-time health monitoring
Published 2025-02-01“…Abstract Background Biosensors are tools that are products of amalgamation of biological constituents and physicochemical elements so as to detect analytes, based on signal production which is measurable. …”
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20231
Decadal in situ hydrological observations and empirical modeling of pressure head in a high-alpine, fractured calcareous rock slope
Published 2025-04-01“…This study advances the understanding of alpine hydrology and geomorphology by providing new insights into deep groundwater processes and their implications for slope stability.…”
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20232
hsa_circRNA_092488 Exacerbates the Progression of Deep Vein Thrombosis Through the NLRP3/NF-κB Signaling Pathway
Published 2025-06-01“…Circular RNA (circRNA) has become a new focus of research as circRNAs are involved in various biological processes including the progression of DVT. This study explored the upregulation of hsa_circRNA_092488 in DVT patients. …”
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20233
A Statistical Approach for Characterizing the Behaviour of Roughness Parameters Measured by a Multi-Physics Instrument on Ground Surface Topographies: Four Novel Indicators
Published 2024-11-01“…Firstly, the study focuses on detecting and explaining parameter disturbances in raw data by identifying and quantifying outliers of the parameter’s values, as a new first indicator. …”
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20234
Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy
Published 2025-02-01“…The four prioritized protein-coding genes were mainly enriched in the regulation of apoptotic and death processes. In addition, GMPR was associated with both GO and GD in a consistent direction. …”
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20235
MicroRNA Expression Profiling to Identify and Validate Reference Genes for the Relative Quantification of microRNA in Rectal Cancer.
Published 2016-01-01“…<h4>Introduction</h4>MicroRNAs (miRNAs) play important roles in regulating biological processes at the post-transcriptional level. Deregulation of miRNAs has been observed in cancer, and miRNAs are being investigated as potential biomarkers regarding diagnosis, prognosis and prediction in cancer management. …”
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20236
FrameBoost: Advanced Video Analytics With Inference Trigger Frame Selection via Tracking Error Estimation
Published 2025-01-01“…While continuous video streams offer rich data, processing every frame is computationally intensive. …”
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20237
Remote Sensing Evidence of Blue Carbon Stock Increase and Attribution of Its Drivers in Coastal China
Published 2025-07-01“…Synergistic interactions were also detected, e.g., NDVI and precipitation, enhancing the effects beyond those of single factors, which indicates that a wetter climate may boost NDVI’s carbon sequestration. …”
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20238
Perspectives on the Use of Transthoracic Echocardiography Results for the Prediction of Ventricular Tachyarrhythmias in Patients with Non-ischemic Cardiomyopathy
Published 2022-07-01“…Chi-square, Fischer, Manna-Whitney, single-factor logistic regression (LR), and multi-factor LR were used for data processing and analysis and for predictive modelling. …”
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20239
Exogenous γ-aminobutyric acid mitigates drought-induced impairments in Thymus daenensis Celak by regulating physiological traits, antioxidant enzymes and essential oil constituents...
Published 2025-03-01“…Abstract Drought stress is one of the most significant environmental challenges, leading to various changes in the physiological processes of plants. Gamma-aminobutyric acid (GABA) is an essential biomolecule that plays a critical role in regulating growth and stress signaling. …”
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20240
The Impact of COVID-19 on Dental Clinic Transmission: Leveraging Internet of Things Technology
Published 2025-03-01“…It also evaluated the potential of wearable sensors as part of the Internet of Things (IoT) to prevent cross-infection.Material and Methods: Swab samples were collected from surfaces and air filters in dental clinics and analyzed using RT-PCR both before and after disinfection processes. Clinicians also used IoT-enabled wearable sensors and completed surveys (n=100) evaluating the impact of these technologies on infection control practices. …”
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