Gene Flow and Abundance of a Tropical Fruit Fly in a Horticultural Landscape Mosaic in Eastern Australia Is Limited by Cleared Grazing Land and Area‐Wide Management by James L. Ryan, Anthony R. Clarke, Alexander M. Piper, Susan Fuller, Peter J. Prentis

“…ABSTRACT Landscape ecology and genetics provide important analytical frameworks for investigating the effect of environmental features on ecological processes. Few empirical studies, however, have simultaneously tested how landscape characteristics influence spatial patterns of gene flow and abundance of pest insects in heterogeneous environments. …”
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By modulating miR‐525‐5p/Bax axis, LINC00659 promotes vascular endothelial cell apoptosis by Xizheng Zhu, Beijia Chen, Hui Xu

“…Endothelial cells play a crucial role in the processes vasoconstriction, platelet activation, and blood coagulation and are an integral part of the vascular response to injury resulting in thrombus formation. …”
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HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus. by Xizhi Feng, Karthik Krishnan, Daryl L Richie, Vishukumar Aimanianda, Lukas Hartl, Nora Grahl, Margaret V Powers-Fletcher, Minlu Zhang, Kevin K Fuller, William C Nierman, Long Jason Lu, Jean-Paul Latgé, Laura Woollett, Simon L Newman, Robert A Cramer, Judith C Rhodes, David S Askew

“…In yeast and other fungi, the accumulation of unfolded proteins is detected by the ER-transmembrane sensor IreA/Ire1, which responds by cleaving an intron from the downstream cytoplasmic mRNA HacA/Hac1, allowing for the translation of a transcription factor that coordinates a series of adaptive responses that are collectively known as the unfolded protein response (UPR). …”
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The effect of Remicade Trough Level on Disease Activity in a Selected Sample of Iraqi Rheumatoid Arthritis Patients by Reem G Hussein, Mohammed Qasim Yahya Malallah A. Al-Atrakji

“…Infliximab is a chimeric monoclonal IgG antibody that specifically targets tumor necrosis factor, a crucial material associated with pathogenic processes. Remicade is an original medication of infliximab. …”
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Relationship between apoptosis markers and the severity of coronary atherosclerosis and clinical and paraclinical characteristics of patients with coronary artery disease by E. A Zakharyan, I. I Fomochkina

“…All subjects were studied for the serum level of apoptosis markers Bcl-2, Bax, Bcl-2/Bax, TRAIL and p53. Statistical processing was carried out using the Statistica 10.0 software. …”
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Laser confocal microscopy of corneal nerve fibers in patients with burning eye syndrome and dry eye disease by T. N. Safonova, Z. V. Surnina, E. S. Medvedeva

“…The method of laser confocal microscopy of the cornea can be used to detect changes in corneal nerve fibers associated with the occurrence of neuropathic pain syndrome.…”
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Deep learning-based automated tool for diagnosing diabetic peripheral neuropathy by Qincheng Qiao, Juan Cao, Wen Xue, Jin Qian, Chuan Wang, Qi Pan, Bin Lu, Qian Xiong, Li Chen, Xinguo Hou

“…Subsequently, an image processing algorithm was designed to automatically extract and quantify various morphological parameters of CNFs. …”
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Redox metabolic disruptions in the honey bee brain following acute exposure to the pyrethroid deltamethrin by Máté Mackei, Fanni Huber, Barnabás Oláh, Zsuzsanna Neogrády, Gábor Mátis

“…Moreover, pronounced lipid peroxidation was detected in the highest-dose group, as indicated by increased malondialdehyde (MDA) levels; however, H2O2 levels were unchanged, suggesting the effective activation of ROS-scavenging adaptation mechanisms. …”
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Blue Vane and Pan Traps Are More Effective for Profiling Multiple Facets of Bee Diversity in Subtropical Forests by Ting-Ting Xie, Ming-Qiang Wang, Yi Li, Cheng-Yong Su, Dan Zhang, Qing-Song Zhou, Ze-Qing Niu, Feng Yuan, Xiu-Wei Liu, Ke-Ping Ma, Chao-Dong Zhu, Jia-Sheng Hao, Douglas Chesters

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Therapeutic role of miR-26a on cardiorenal injury in a mice model of angiotensin-II induced chronic kidney disease through inhibition of LIMS1/ILK pathway by Weijie Ni, Yajie Zhao, Jinxin Shen, Qing Yin, Yao Wang, Zuolin Li, Taotao Tang, Yi Wen, Yilin Zhang, Wei Jiang, Liangyunzi Jiang, Jinxuan Wei, Weihua Gan, Aiqing Zhang, Xiaoyu Zhou, Bin Wang, Bi-Cheng Liu, Yuanyuan Ji

“…Chronic kidney disease (CKD) is associated with common pathophysiological processes, such as inflammation and fibrosis, in both the heart and the kidney. …”
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Analysis of Volatile Organic Compounds in Low-temperature Conditioning of Kiwifruit by HS-SPME-GC-MS Combined with Chemometrics Methods by Zhixin GUO, Wei ZHANG, Yingjie GUO, Xiaomei CHENG, Dengni LAI, Shuangping CHEN, Gaoyang LI, Xiangrong ZHU

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External phantom-based validation of a deep-learning network trained for upscaling of digital low count PET data by Anja Braune, René Hosch, David Kersting, Juliane Müller, Frank Hofheinz, Ken Herrmann, Felix Nensa, Jörg Kotzerke, Robert Seifert

“…However, there are strong limitations in terms of quantitative accuracy and detectability of small lesions.…”
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Farm-to-fork changes in poultry microbiomes and resistomes in Maputo City, Mozambique by Natalie Olson, Frederica Lamar, Hermógenes Mucache, José Fafetine, Joaquim Saíde, Amélia Milisse, Denise R. A. Brito, Kelsey J. Jesser, Karen Levy, Matthew C. Freeman, Maya L. Nadimpalli

“…We also found that while all potentially pathogenic bacteria and many high-risk antimicrobial resistance genes persisted from production and market through processing, some resistance genes were detected on carcass samples only after processing, suggesting human or environmental contamination is occurring within markets. …”
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Megatsunami deposits and range expansion of cold-temperate marine species towards the tropics in glacial times by Sérgio P. Ávila, Raphaël Paris, Ricardo S. Ramalho, Carlos S. Melo, Esther Martín-González, Emilio Rolán, Patrícia Madeira, Gonçalo C. Ávila, João M. Porteiro, António M. Medeiros, Filipa Naughton, Fátima Abrantes, Gustavo M. Martins, Markes E. Johnson, José Madeira

“…Highlights Megatsunami deposits are used to unveil biogeographic patterns and processes in the Macaronesian archipelagos. …”
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Coniferaldehyde reverses 3-nitropropionic acid-induced Huntington’s disease pathologies via PKM2 restoration and JAK2/STAT3 inhibition by Ayooluwa Gabriel Ibiayo, Peeraporn Varinthra, Mukundan Nagarajan, Ingrid Y Liu

“…CFA treatment attenuates these pathological processes by reducing ROS and apoptosis, restoring PKM2 expression, and modulating glial activation and proinflammatory cytokines (IL-6 and IL-1β). …”
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Prevalence of Extended-Spectrum Beta-Lactamase (ESBL)–Producing Escherichia coli in Humans, Food, and Environment in Kathmandu, Nepal: Findings From ESBL E. coli Tricycle Project by Jyoti Acharya, Runa Jha, Tulsi Ram Gompo, Sharmila Chapagain, Lilee Shrestha, Nisha Rijal, Anjana Shrestha, Pragya Koirala, Suraj Subedi, Binita Tamang, Hari Prasad Kattel, Bishal Khaniya, Basudha Shrestha, Aruna Karki, Ram Prasad Adhikari, Sanita Kayastha, Prasil Pradhan, Sarada Duwal Shrestha, Bijendra Raj Raghubanshi, Heera Tuladhar, Palpasa Kansakar, Saugat Shrestha, Priyanka Shrestha, Binay Shrestha, Ricardo J. Soares Magalhaes, Manish Kakkar, Arunkumar Govindakarnavar, Allison Gocotano, Reuben Samuel

“…ESBL-producing E. coli was detected in all wastewater samples tested except for the upstream river. …”
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Adaptation of Diqing Tibetan pigs to hypoxic and cold environments through extramedullary hematopoiesis and uncoupled thermogenesis in the liver by Xinpeng Li, Xinxing Dong, Shuhong Zhao, Yunlong Ma, Siqi Jin, Chunlu Zhou, Yi Lan, Shuyuan Luo, Bin Ni, Hongjiang Wei, Dawei Yan

“…Additionally, a class of hepatocytes capable of converting metabolic energy into heat through uncoupling processes was identified, which assists in the adaptation to the cold environments of the plateau. …”
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Targeting revascularization via tryptophan-indole-NETs axis: the synergistic power of acupuncture and rt-PA thrombolysis in ischemic stroke by Siqi Chang, Siqi Chang, Yi Zhao, Yi Zhao, Chengfeng Li, Chengfeng Li, Xinyu Liu, Xinyu Liu, Zixuan Fang, Zixuan Fang, Zihao Peng, Zihao Peng, Mingliang Gao, Mingliang Gao, Yawen Xia, Yawen Xia, Yawen Xia, Guangxia Ni, Guangxia Ni

“…This study aims to explore the synergistic power and underlying mechanisms of XNKQ method and recombinant tissue plasminogen activator (rt-PA).MethodsA rat embolic stroke model was utilized to replicate the pathological processes of ischemic stroke. The effects on cerebral perfusion and vascular leakage were assessed in vivo and in vitro. …”
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Quantifying task-locked information transmission between cortical areas with TMS-EEG by Zhaohuan Ding, Wenbo Ma, Leixiao Feng, Mingsha Zhang, Xiaoli Li

“…Objective: This study aims to develop TMS-EEG (Transcranial magnetic stimulation combined with EEG) technology to detect task-locked neural network activation and dynamically quantify information transmission. …”
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Full-length transcriptome analysis of male and female gonads in Japanese Eel (Anguilla japonica) by Jiangling Li, Jingjie Liang, Mengyang Wang, Yuewen Jiang, Wen Li, Mingxi Huang, Yan Huang, Yangjie Xie, Jianchun Chen, Tiansheng Chen

“…Additionally, 1,210 differentially expressed genes were detected. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses revealed significant pathways involved in cell cycle regulation, metabolic processes, apoptosis, and hormone activity. …”
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