In Situ Growth of Au NPs on Nitrogen-Doped Graphene Quantum Dots Decorated Graphene Composites for the Construction of an Electrochemical Immunosensor and Its Application in CEA De... by Zhengzheng Yan, Lujie Wang, Fei Yan

Get full text

Optimization of Ultrasonic-Enzymatic-Assisted Extraction of Flavonoids from Sea Buckthorn (<i>Hippophae rhamnoides</i> L.) Pomace: Chemical Composition and Biological Activities by Wenyu Suo, Wenzhe Wang, Dajing Li, Haihong Wu, Haiyan Liu, Wuyang Huang, Yanhong Ma

“…Sea buckthorn pomace (SBP) is a rich source of flavonoid compounds with potential healthy properties. This study optimized ultrasonic-enzymatic-assisted extraction (UEAE) of flavonoids from SBP and investigated its chemical composition and biological activities. …”
Get full text

An LJDRNN-based efficient energy intensity prediction in carbon fiber composite material manufacturing process by Rangaswamy Nikhil, Karthikeyan A G, Prabhu Loganathan, Tabrej Khan, Tamer A Sebaey

“…Carbon Fibers (CFs) are usually derived from a polyacrylonitrile precursor during composite fiber production. Due to high-temperature needs, the CF composite manufacturing process is considerably energy-consuming and costly. …”
Get full text

Response Surface Methodology Optimization of Time-Resolved Fluorescence Immunoassay for Rapid Detection of AflatoxinB₁ in Yellow Rice Wine by Mengjie Zhu, Dun Wang, Du Wang, Jing Dong, Xue Wang, Qi Zhang, Man Xiao

“…Statistical experimental designs were used to optimize the process of this rapid detection of AFB₁ in yellow rice wine. …”
Get full text

Dual-Valence Copper Nanostructures with Cu⁺/Cu²⁺ Interfaces for High-Sensitivity Glucose Electrochemical Sensing by Zhipeng Yu, Pengxu Yan, Yilei Sheng, Chengwei Zhang, Zhun Qiao, Qikui Fan, Chuncai Kong, Zhimao Yang

Get full text

SOE: A Multi-Objective Traffic Scheduling Engine for DDoS Mitigation with Isolation-Aware Optimization by Mingwei Zhou, Xian Mu, Yanyan Liang

“…To address this, we propose SchedOpt Engine (SOE), a scheduling framework formulated as a discrete multi-objective optimization problem. The goal is to optimize four conflicting objectives: a benign traffic acceptance rate (BTAR), malicious traffic interception rate (MTIR), server load balancing, and malicious traffic isolation. …”
Get full text

Mechanical Response and Anti-Reflective Crack Design in New Asphalt Overlays on Existing Asphalt Overlaying Composite Portland Cement Pavement by Jianping Gao, Zhixiong Qiu, Chunlong Xiong

“…This system was constructed to solve problems with the detection, evaluation, and structural and material design of asphalt rehabilitation for the prevention and control of asphalt reflection cracks in asphalt overlaying composite Portland cement pavement. …”
Get full text

Optimization (Central Composite Design) and Validation of HPLC Method for Investigation of Emtricitabine Loaded Poly(lactic-co-glycolic acid) Nanoparticles: In Vitro Drug Release a... by Gurinder Singh, Roopa S. Pai

Get full text

Detection of Pesticide Residues Using Three-Dimensional SERS Substrate Based on CNTs/Ag/AgNWs/SiO₂ by Jianjun Ding, Niansong Liu, Ganglin Wang, Naiyu Guo, Chao Sun

“…Additionally, the genetic algorithm (GA)-optimized Back Propagation (BP) neural network was introduced for the quantitative analysis of thiram concentrations. …”
Get full text

Liquid chromatography-high resolution mass spectrometry based analysis of persistent mobile organic compounds in aqueous samples: Method development and optimization by Kyriaki Anagnostopoulou, Vasileios Alampanos, Eleni Evgenidou, Dimitra A. Lambropoulou

“…A central composite design and desirability function (DF) approach were used to optimize the HRMS analysis, while the most suitable SPE cartridge, column, and mobile phase composition were carefully selected through experimental trials. …”
Get full text

Quality by design-based optimization and HP-TLC densitometric standardization of Theobroma cacao L. extract as a nutraceutical supplement by Atith Muppayyanamath, Atith Muppayyanamath, Darasaguppe R. Harish, Vinayak Mastiholimath, Priyanka P. Patil, Priyanka P. Patil, Vishal S. Patil, Harsha V. Hegde, Subarna Roy

“…Utilizing a Quality by Design (QbD) approach with Design Expert (DoE) software, we optimized CE tablets via direct compression. The central composite design (CCD) included five center points, with Avicel PH − 101 and croscarmellose sodium (CCS) as factors, and disintegration time, hardness, and % loss due to friability as measurements.ResultsAmong the 13 formulations, batch F-9 emerged as the optimized one within the design space, containing 35% Avicel PH − 101 and 5% CCS. …”
Get full text

Identification and optimization of relevant factors for chronic kidney disease in abdominal obesity patients by machine learning methods: insights from NHANES 2005–2018 by Xiangling Deng, Lifei Ma, Pin Li, Mengyang He, Ruyue Jin, Yuandong Tao, Hualin Cao, Hengyu Gao, Wenquan Zhou, Kuan Lu, Xiaoye Chen, Wenchao Li, Huixia Zhou

“…Conclusion CatBoost models, along with glycolipid metabolism indexes and dietary antioxidant intake, are effective for early CKD detection in patients with abdominal obesity.…”
Get full text

An efficient p-n type based (NiO/CeO2) hybrid composite photocatalyst and its performance for cationic dye degradation: Probable degradation pathways, optimization activities, and... by Manoj Kumar, Atikur Rahman, Vijay Pratap Singh

Get full text

Exploring a green and precise approach based on graphene oxide-cobalt ferrite nanocomposite for detection and quantification of vitamin B9 and antibacterial assessment by Zahra Khaleghi, Rouhollah Khani, Maryam Moudi

“…Four parameters of pH, sorbent dose, temperature, and sonication time were selected as effective variables on the process and optimized by central composite design (CCD). Under optimized conditions, the linear range, limit of detection, intra-day (repeatability) and inter-day (intermediate) precision were obtained 15–750 ng mL−1, 3.96 ng mL−1, 3.3–3.8%, and 4.2–4.9%, respectively. …”
Get full text

Modelling habitat requirements of Alburnus atropatena in the Jajroud protected River by Saleh Mahmoudi, Asghar Abdoli

“…The arithmetic mean method had the highest values ​​of these measures and had detected as the high-error model.Conclusion: This is the first study related to the ecology of A. atropatenae in Iran, which has identified the optimal habitat of this species. …”
Get full text

Tailoring a MOF-on-MOF (ZIF-8-on-NH2-MIL-53(Al)) Hybrid Composite for Micro Solid Phase Extraction of Furosemide in artificial biological fluids prior to LC-q-TOF/MS detection by Zinar Pinar Gumus, Mustafa Soylak

“…Given the clinical significance of furosemide and its dependable application in athletics, this research employed the ''MOF-on-MOF'' hybrid material composite to leverage the synergistic effects of various components for detecting this drug in biological samples. …”
Get full text

Preparation of g-C₃N₄/Co₃O₄/NS-CQDs Composite Materials and Their Application in the Detection of Hydrogen Peroxide and Glucose by Chang Feng, Yufeng Chen, Weie Wang, Yanan Niu, Xi Cao, Yuguang Lv

“…The highest activity of g-C₃N₄/NS-CQDs/Co₃O₄ was at 5% floral Co₃O₄, being efficient due to Co₃O₄’s electron-transfer acceleration and hydroxyl-radical mechanism. Under optimal conditions, the composite detected H₂O₂ (10.0–230.0 μM, detection limit of 0.031 μM) and glucose (10.0–650.0 μM, detection limit of 1.024 μM).…”
Get full text

Research Progress on Composite Structure of Warships in Impact Protection by Tao ZHANG, Qingzhen SUN, Lei ZHANG, Xiangmei LI

“…It also emphasized the pivotal role of simulation technology in design optimization and performance prediction, as well as the potential of additive manufacturing and laser processing technologies in improving production efficiency and product quality. …”
Get full text

Effects of Ply Misalignment in Material Characterization of Composite Laminates by Michael Franz, Racim Radjef, Boris Eisenbart, Sandro Wartzack

Get full text

Submerged Cultivation and Chemical Composition of Hericium erinaceus Mycelium by A. V. Avtonomova, A. V. Bakanov, M. I. Shuktueva, V. A. Vinokurov, O. V. Popova, A. I. Usov, L. M. Krasnopolskaya

“…The yield of the biomass was shown to depend mainly on the carbon source, whereas the content of water soluble polysaccharides depended mainly on the nitrogen source. The optimal medium composition provided the biomass yield of 21-23 g/l in 7 days. …”
Get full text