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481
Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen.
Published 2021-03-01“…In contrast, our analysis detects evidence for significant positive episodic diversifying selection acting at the base of the bat virus lineage SARS-CoV-2 emerged from, accompanied by an adaptive depletion in CpG composition presumed to be linked to the action of antiviral mechanisms in these ancestral bat hosts. …”
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482
Diamagnetic Signature of Beta‐Amyloid (Aβ) and Tau (τ) Tangle Pathology in Alzheimer's Disease: A Review
Published 2025-02-01“…Further research is necessary to refine QSM techniques, optimize acquisition parameters, and develop robust analysis pipelines to improve the sensitivity and specificity of detecting the diamagnetic nature of Aβ and τ aggregates. …”
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483
Evaluating Ice-Temperature Storage Efficacy on Volatile Compounds in Blue Honeysuckle (<i>Lonicera caerulea</i> L.) by Combining GC-IMS and GC-MS
Published 2025-03-01“…These results conclusively establish ice-temperature storage as the optimal method for preserving both biochemical composition and cytological architecture in blue honeysuckle, thereby providing a scientific foundation for optimizing postharvest protocols and advancing cold-chain technologies for perishable berry fruits.…”
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484
AI-Enabled Piezoelectric Wearable for Joint Torque Monitoring
Published 2025-05-01“…High-sensitivity BNNTs/polydimethylsiloxane composite enables precise and dynamic knee motion signal detection. …”
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485
Unveiling the Spatial Variation in Ecosystem Services Interactions and Their Drivers Within the National Key Ecological Function Zones, China
Published 2025-04-01“…The dominant factors in different functional zones influenced ES interactions in a non-stationary manner, with the same factors potentially showing diverse effect types in different sub-regions. Additionally, we detected the dominant role of landscape configuration factors in sub-regions for specific interaction types (e.g., WR-NPP interaction in the SP zones), suggesting the potential for achieving multi-ES synergies through landscape planning without altering landscape composition. …”
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486
The influence of weather conditions during an autumn period on the development of basic wreckers and diseases of agrocenosis of winter wheat in Forest-Steppe zone
Published 2019-01-01“…Through droughty conditions, or over wetting optimal terms of sowing were displaced for later. …”
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487
Design of Microstrip antenna by Integrating Octagonal Patch Configuration for UWB Application
Published 2025-06-01“…An UWB application, breast cancer detection is tested using proposed structure. …”
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488
Molecularly imprinted polypyrrole-based electrochemical sensor for furaldehydes determination in Italian honey samples
Published 2025-06-01“…The electropolymerization conditions for the e-MIP film were optimized using a Face-centered Central Composite Design. …”
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489
Metabolomic profiling of Akebia species: Comparative analysis of bioactive compounds in the pulp of A. trifoliata, A. trifoliata ssp. australis, and A. quinata
Published 2025-05-01“…This study employs UPLC-MS/MS and GC–MS techniques to comprehensively analyze the chemical composition of the pulp from these three species. Among the 1429 metabolites detected and putatively identified, terpenoids, amino acids, flavonoids, and phenolics were predominant. …”
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490
Analysis the Changes of Flavor Profile of Squid Tentacles during the Baking Process Based on Gas Chromatography-Ion Mobility Spectroscopy and Electronic Tongue
Published 2025-06-01“…In the samples with five different baking times, 29 flavor compounds were detected, including 14 aldehydes, 3 ketones, 5 alcohols, 3 esters, 2 acids, and 2 olefins. …”
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491
Antifungal potential of the main compounds of Cuminum cyminum L. in targeting secreted aspartyl proteinase of Candida albicans compared to fluconazole
Published 2024-08-01“…This microorganism changes into an opportunistic fungus due to imbalances in microbiome composition, especially in an impaired immune system condition. …”
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492
Determination of the therapeutic effectiveness of the drug against siphonaptero-sis of cats based on selamectin and praziquantel
Published 2024-12-01“…The drug was used in cats in which the presence of fleas was detected during the examination. Siphonapterosis was suspected in the presence of characteristic clinical signs of the disease. …”
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493
Exploring ultrasound-induced free radical formation: A comparative study in water and sour cherry juice using glutathione and terephthalic acid indicators
Published 2025-01-01“…This study offers key insights into how ultrasound conditions affect FR formation in water and SCJ media by stabilizing them in detectable forms.…”
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494
Comprehensive evaluation of icewine aroma quality based on ROAV and PCA-TOPSIS method
Published 2025-01-01“…The aroma composition and content of 4 icewines exhibited significant differences. 22 important aroma compounds (ROAV>0.1) and 10 key aroma compounds (ROAV>1) were selected through the relative odor activity value (ROAV). …”
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495
Influenza Seasonality in the Tropics and Subtropics - When to Vaccinate?
Published 2016-01-01“…<h4>Background</h4>The timing of the biannual WHO influenza vaccine composition selection and production cycle has been historically directed to the influenza seasonality patterns in the temperate regions of the northern and southern hemispheres. …”
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496
Analysis of Specific Perfluorohexane Sulfonate Isomers by Liquid Chromatography-Tandem Mass Spectrometry: Method Development and Application in Source Apportionment
Published 2022-01-01“…The developed method was then used to quantify the isomeric compositions of PFHxS in the perfluorooctane sulfonate (PFOS) industrial products which contained PFHxS as an impurity, as well as in several kinds of water samples, with the limits of detection for all isomers in the range of 4 to 30 pg/L. …”
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497
Dispersive liquid-liquid microextraction/HPLC techniques for determination of oxytetracycline and doxycycline residues in beef samples: method developments and statistical analysis
Published 2023-04-01“…Several influencing factors associated with the extraction and separation of these antibiotics residues, such as sample size, type and volume of disperser and extraction solvents, centrifugation speed and time, were optimized using Plackett-Burman design and central composite design, while insignificant factors were fixed at values determined using univariate analysis. …”
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498
Ensiling as a Conservation Technique for <i>Opuntia ficus indica</i> (L.) By-Products: Peel and Pastazzo
Published 2024-11-01“…The detected organic acids and silage pH indicate an optimal fermentation process for these by-products. …”
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499
Determination of Victoria blue in water samples using ultrasound-assisted liquid-phase microextraction based on deep eutectic solvents: A comparative study of spectrophotometric an...
Published 2025-03-01“…A central composite design (CCD) was employed to optimize the main parameters, including the initial pH of the aqueous dye solution, and the volume of DES and diluent. …”
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500
Protective effect of Pu-erh tea polysaccharides and catechins compound on immunosuppressive mice
Published 2025-06-01“…In order to investigate the immunomodulatory effects of Pu-erh tea polysaccharides (TP) and catechins (TPC) compound, using immunosuppressive mice induced by cyclophosphamide (Cy) as the research object, the immune indexes of mice were detected by enzyme-linked immunosorbent assay (ELISA) and hematoxylin-eosin (HE) staining section, and the dose of Pu-erh tea polysaccharide with the optimal immune regulation effect was screened, and the effects of TPC compound on immune indexes and metabolite composition of immunosuppressive mice were investigated. …”
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