MiR-638 suppresses the progression of oral squamous cell carcinoma through wnt/β-catenin pathway by targeting phospholipase D1 by Kai-Liang Tang, Han-Ying Tang, Yi- Du, Tian Tian, Shi-Jiang Xiong

“…Objective The current study aimed to explore the function of miR-638 on the progression of oral squamous cell carcinoma (OSCC) and relevant molecular mechanisms.Methods Expression profile of miR-638 in OSCC tissues and cells was detected using quantitative real-time polymerase chain reaction (qRT-PCR) method. …”
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Flavokawain B Weakens Gastric Cancer Progression via the TGF-β1/SMAD4 Pathway and Attenuates M2 Macrophage Polarization by Yongzhao Zhu, Weining Fan, Yuanzhen Wang, Huan Ding, Shaoqi Yang, Fang He

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METTL14-mediated miR-122-5p maturation stimulated tumor progression by targeting KAT2A in hepatocellular carcinoma by Xiangyu Fan, Wenjuan Qiao, Xu Guo, Jiaqi Wang, Lisong Zhao

“…Therefore, this study was aimed to explore the mechanism of miR-122-5p in regulating hepatocellular carcinoma (HCC) progression. mRNA expression and transfection efficiency were detected by RT-qPCR. …”
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SPI1 Mediates N-Myristoyltransferase 1 to Advance Gastric Cancer Progression via PI3K/AKT/mTOR Pathway by Ping Qiu, Xing Li, Min Gong, Ping Wen, Jianbo Wen, Linfang Xu, Guiliang Wang

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Oral Combined Probiotics Clostridium butyricum and Akkermansia muciniphila Inhibits the Progression of 4T1 Breast Cancer by Activating Bcl‐2/Bax Pathway by Xiaowei Li, Dengxiong Hua, Daoyan Wu, Wei Hong, Yingqian Kang, Lei Tang, Qin Yang, Xinxin Wang, Boyan Li, Renmin Li, Zhenghong Chen, Guzhen Cui

“…Cell proliferation was evaluated using the MTT assay, and apoptosis was detected by flow cytometry. Results The results indicated that oral administration of CB and AKK possesses the capability to inhibit the progression of 4T1 breast cancer; however, the combined treatment with both strains (CB‐AKK) exhibited significantly superior effects compared to each individual strain. …”
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Correlation between Genetic Variations and Serum Level of Interleukin 28B with Virus Genotypes and Disease Progression in Chronic Hepatitis C Virus Infection by Ahmed Al-Qahtani, Mashael Al-Anazi, Ayman A. Abdo, Faisal M. Sanai, Waleed Al-Hamoudi, Khalid A. Alswat, Hamad I. Al-Ashgar, Mohammed Q. Khan, Ali Albenmousa, Nisreen Khalaf, Nisha Viswan, Mohammed N. Al-Ahdal

“…The aim of the study was to correlate the serum level of IL28B in HCV-infected patients with virus genotype/subgenotype and disease progression. IL28B serum level was detected and variations at five single nucleotide polymorphisms (SNPs) in IL28B gene region were genotyped and analyzed. …”
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METTL3 regulates Ambra1 expression in an m6A-YTHDF2-dependent manner to promote mantle cell lymphoma progression by Shujun Li, Zhiping Jiang, Wenjia Wei, Simin Deng, Tianjing Duan

“…Abstract Background Ambra1 has recently been identified as a key regulatory factor in the progression of mantle cell lymphoma (MCL). The objective of this study was to investigate the biological role and molecular mechanism of Ambra1 in MCL. …”
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HOXA5 Derives the Malignant Progression and Cisplatin Resistance of Esophageal Squamous Cell Carcinoma by Regulating USP18‐Mediated IFI27 Deubiquitination by Qiang Wang, Shiheng Ren, Zheng Pan, Yuxin Chen, Xiangyan Liu

“…Interferon alpha‐inducible protein 27 (IFI27) has been reported to be associated with ESCC progression. This study is designed to explore the role and mechanism of IFI27 in the cisplatin (DDP) resistance of ESCC. …”
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Long-term resident adipose-derived stromal stem cells in the microenvironment remodeling BLCA cell stemness and EMT promotes bladder cancer progression by Denggao Huang, Na Guo, Yanling Peng, Zhenyu Nie, Yuanhui Gao, Hui Cao, Shunlan Wang, Mei Chen, Xiaohong Wen, Zhaojun Wang, Linlin Zheng, Haowei He, Yong Sun, Yang Chen, Shufang Zhang

“…Abstract The role of adipose-derived stromal stem cells (ADSCs) in BLCA progression is unclear. We investigated the effects of invasion, stemness, Epithelial-mesenchymal transition (EMT), and drug resistance of BLCA cells co-cultured with ADSCs for a long period of time. …”
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Inhibition of ATG5-mediated autophagy maintains PMAIP1 stability to promote cell apoptosis and suppress triple-negative breast cancer progression by Fangjian Shang, Hongfeng Nie, Liyan Du, Jin Shang, Xiangquan Song, Ya Chen, Hui Li, Zhuo Wang, Yixin Qi, Liyan Zhao

“…Conclusion Inhibition of ATG5-mediated autophagy maintains PMAIP1 stability, thereby promoting cell apoptosis and suppressing TNBC progression.…”
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CH25H Promotes Autophagy and Regulates the Malignant Progression of Laryngeal Squamous Cell Carcinoma Through the PI3K‐AKT Pathway by Zhenfei Xiang, Senquan Yu, Yuxin Xu, Huacai Xiong, Danfei Hu, Qun Li, Zhenhua Wu

“…We further investigated CH25H's impact on tumor growth, autophagy, and the PI3K‐AKT pathway at the animal level and found that CH25H promoted autophagy of LSCC cells and inhibited the PI3K‐AKT pathway, and ultimately inhibiting the progression of LSCC. Conclusions In summary, CH25H promotes autophagy and affects the malignant progression of LSCC through the PI3K‐AKT pathway.…”
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Tyrosine phosphatase SHP2 promoted the progression of CRC via modulating the PI3K/BRD4/TFEB signaling induced ferroptosis by Jian Chen, Wei Li, Cheng Zhang, Dihao Wen, Cheng Jiao

“…Conclusion SHP2 advances CRC progression by modulating TFEB-mediated ferritinophagy, suppressing ROS and ferroptosis. …”
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P-104 PREVALENCE AND SEVERITY OF MASLD AND ITS ASSOCIATION WITH METABOLIC COMORBIDITIES: INSIGHTS FROM A LINKAGE TO CARE PROGRAM FOR FATTY LIVER DISEASE by Ignacio Roca, Omar Galdame, Maria Del Carmen Puente, Nicolas Dominguez, Rocío Del Carmen Chávez Gonzáles, Manuel Barbero, Lucia Navarro, Fernando Cairo

“…This study aimed to conduct a fatty liver detection campaign as part of a linkage to care program for MASLD at Hospital El Cruce in Buenos Aires and to evaluate its association with metabolic comorbidities. …”
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Seroprevalence of hepatitis B among the general population in Shandong Province, Eastern China, an update 30 years after the implementation of the neonatal vaccination program by Bingyu Yan, Xiaomeng Zhang, Jingjing Lv, Yi Feng, Xin Meng, Xiaojuan Lin, Yan Zhang, Suting Wang, Feng Ji, Meng Chen, Xinyu Yuan, Zexin Tao, Li Zhang

“…Conclusion The Shandong Province has achieved substantial success in controlling HBV infection among the younger generation through the newborn routine vaccination program. To accelerate progress towards the goal of eliminating hepatitis B in the province, additional strategies should also be adopted in parallel, including increasing diagnostic coverage, expanding antiviral treatment, and enhancing hepatitis B vaccine coverage for HBV-susceptible adults.…”
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Design and Development of an iOS Application for Early Detection and Monitoring of Scoliosis Using Core Motion by Gwynneth Isviandhy, Adi Suryaputra Paramita

“…This research aims to design an iOS-based application to help users independently track the progression of scoliosis. The application employs Core Motion technology to detect and monitor the degree of spinal curvature. …”
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THE EFFECTIVENESS OF EARLY DETECTION OF KAMTIB DISTURBANCES THROUGH CORRECTIONAL GREETING ACTIVITIES AT RUTAN IIB MENGGALA by Fadhel Riyantyo, Markus Marselinus Soge

“… This research explores the effectiveness of early detection of security disturbances through the Salam Pemasyarakatan program at Rutan IIB Menggala. …”
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Development and Application of a Portable Environmental DNA Test for the Detection of Rafetus swinhoei in Viet Nam by Tracie A. Seimon, Nguyen Van Long, Minh Le, Timothy E. M. McCormack, Tham Thi Nguyen, Hanh Ngo, Nguyen Tai Thang, Thuy Hoang, Steven G. Platt, Hoang Van Ha, Nguyen Van Trong, Brian Horne, Colleen A. Barrett, Denise McAloose, Paul P. Calle

“…Species‐specific quantitative polymerase chain reaction (qPCR) testing can be used to detect eDNA in samples collected from the environment. eDNA trials to detect R. swinhoei were initiated by the Asian Turtle Program and Washington State University in 2013. …”
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Evaluation of machine learning methods for the retrospective detection of ovarian cancer recurrences from chemotherapy data by A.D. Coles, C.D. McInerney, K. Zucker, S. Cheeseman, O.A. Johnson, G. Hall

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Introducing an ensemble method for the early detection of Alzheimer's disease through the analysis of PET scan images by Arezoo Borji, Taha-Hossein Hejazi, Abbas Seifi

“…This classification is based on a thorough examination of Positron Emission Tomography (PET) scan images obtained from the ADNI dataset, which provides a comprehensive understanding of the disease's progression. Several deep-learning and traditional machine-learning models have been used to detect AD. …”
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Microcalcifications Detected as an Abnormality on Screening Mammography: Outcomes and Followup over a Five-Year Period by Melissa Craft, Anne M. Bicknell, Georges J. Hazan, Karen M. Flegg

“…This study highlights the effectiveness of an Australian screening program in diagnosing malignancy in women with screen detected microcalcification. …”
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