Small nucleolar RNA SNORD13H suppresses tumor progression via FBL-dependent 2′-O-methylation in hepatocellular carcinoma by Minglu Zhang, Minglu Zhang, Minglu Zhang, Minglu Zhang, Jianbo He, Jianbo He, Jianbo He, Jianbo He, Rao Fu, Rao Fu, Rao Fu, Rao Fu, Guojian Bao, Guojian Bao, Guojian Bao, Yijun Lu, Yijun Lu, Yijun Lu, Zechuan Zhang, Zechuan Zhang, Zechuan Zhang, Jiawu Yan, Jiawu Yan, Jiawu Yan, Jialu Ding, Jialu Ding, Jialu Ding, Fei Yang, Fei Yang, Fei Yang, Fei Yang, Beicheng Sun, Beicheng Sun, Beicheng Sun, Beicheng Sun

“…The diminution of SNORD13H activates the RAS pathway, contributing to the progression of HCC.DiscussionOur study establishes SNORD13H as a dual-function regulator in HCC progression. …”
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Oxidative Phosphorylation-Related Signature Participates in Cancer Development, and PTPRG Overexpression Suppresses the Cancer Progression in Clear Cell Renal Cell Carcinoma by Liang Huang, Yu Xie, Weiqing Han, Shusuan Jiang, Lingfeng Zeng

“…We believe this study discovered a novel mechanism of ccRCC pathological progression and will provide promising targets for therapeutic strategy development.…”
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OGT-induced O-GlcNAcylation of NEK7 protein aggravates osteoarthritis progression by enhancing NEK7/NLRP3 axis by Chunlei He, Qiang Wu, Zhaogan Zeng, Yadong Yang, Huabin He, Meiyu Hu, Sheng Liu

“…The effects of OGT knockout on OA progression were detected through Safranin O staining, immunohistochemical staining and OARSI score evaluation. …”
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CAFs-released exosomal CREB1 promotes cell progression and immune evasion in thyroid cancer via the positive regulation of CCL20 by Chen Zheng, Hu Hei, Yifei Zhai, Wenbo Gong, Runfang Zhang, Songtao Zhang

“…Exosomal CREB1 knockdown receded cell progression and enhanced CD8+ T function by mediating CCL20. …”
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KAT5 Inhibitor NU9056 Suppresses Anaplastic Thyroid Carcinoma Progression through c-Myc/miR-202 Pathway by Wenjing Xu, Liwei Xie, Yingying Yang, Jiayu Xu, Shang Cai, Ye Tian

“…Knockdown of miR-202 suppressed ATC cell progression, while forced expression of miR-202 partially blocked the inhibitory effect of NU9056 on ATC cells. …”
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CSF3 promotes colorectal cancer progression by activating p65/NF-κB signaling pathway and inducing an immunosuppressive microenvironment by Junfeng Xu, Na Li, Hui Xie, Changwei Duan, Xingchen Liao, Ruoran Li, Heng Zhang, Yuanming Pan, Xianzong Ma, Shuwen Du, Jianqiu Sheng, Xin Wang, Lang Yang, Peng Jin

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Next-generation sequencing of CCR5, CXCR4, and IFNAR1 variants in relation to HIV-1 disease progression and ART response by Kubra Cigdem Pekkoc-Uyanik, Zeynep Gizem Todurga-Seven, Andleeb Shahzadi, Haktan Sonmez, Sevcan Mercan, Bilgul Mete, Fehmi Tabak

“…Our results demonstrate that intronic variations in the IFNAR1 rs2856973:T > A and CXCR4 rs2680880:A > T genes can contribute to modifications in HIV progression and CD4 + T recovery under ART.…”
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hsa_circRNA_092488 Exacerbates the Progression of Deep Vein Thrombosis Through the NLRP3/NF-κB Signaling Pathway by Jian Wang, Binghui Du

“…The proliferation, migration, cell cycle progression, and apoptosis of transfected cells were measured by CCK-8 assay, transwell assay, and flow cytometry. …”
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RETRACTED: Silencing circular RNA VANGL1 inhibits progression of bladder cancer by regulating miR‐1184/IGFBP2 axis by Dengke Yang, Haining Qian, Zhen Fang, An Xu, Shutian Zhao, Bingyan Liu, Dong Li

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Identification and validation of a lenvatinib resistance-related prognostic signature in HCC, in which PFKFB4 contributes to tumor progression and lenvatinib resistance by Jinfeng Wang, Jianfei Shi, Lili Mi, Ning Li, Xin Han, Man Zhao, Xiaoling Duan, Guangjie Han, Jiaojiao Hou, Fei Yin

“…PFKFB4 promotes tumor progression and lenvatinib resistance, highlighting its potential as a novel therapeutic target for HCC. …”
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Systemic immune inflammation index and systemic inflammation response index predict frailty progression in older patients undergoing elective orthopedic surgery by Guanghan Gao, Zitian Zheng, Fei Wang, Yaonan Zhang, Lei Shi, Lin Wang, Hongyu Wang, Qingyun Xue

“…LASSO regression was used to identify important predictive variables, and multivariate logistic regression was employed to assess the associations between SII/SIRI and frailty progression. Restricted cubic splines (RCS) were used to detect potential non-linear relationships between them. …”
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Association between non-insulin-based insulin resistance indicators and frailty progression: a national cohort study and mendelian randomization analysis by Hui Tian, Yong-meng Li, Cheng-qiang Wang, Guo-qiang Chen, Ying Lian

“…Conclusions The non-insulin-based IR indicators, including TyG index, METS-IR and eGDR, were independently associated with the frailty progression and physical function decline. Monitoring and managing abnormal glucose metabolism should be recommended as a part of comprehensive strategies to prevent or delay the progression of frailty.…”
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Virtual Reality Portable Perimetry and Home Monitoring of Glaucoma: Retention and Compliance over a 2-year Period by Runjie B. Shi, MD, PhD, Leo Y. Li-Han, PhD, Irfan N. Kherani, MD, FRCSC, Graham E. Trope, PhD, FRCSC, Yvonne M. Buys, MD, FRCSC, Willy Wong, PhD, Moshe Eizenman, PhD

“…The years required to detect progression were also compared between HFA and TPP tests. …”
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Effectiveness of incorporating the graf method into a universal neonatal ultrasound screening program for early diagnosis of developmental dysplasia of the hip in the Taiwanese pop... by Jou-Hua Wang, Shu-Hsin Yao, Ting-Ming Wang, Chii-Jeng Lin, Chang-Hao Lin, Chun-Ho Chen

“…Abstract Purpose This study evaluated the effectiveness of integrating Graf method into the universal neonatal screening program for detecting developmental dysplasia of the hip (DDH) in Taiwanese population. …”
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Change in TB diagnostic profile after introduction of GeneXpert MTB/RIF assay in National TB Program of Armenia, 2013-2017 by Eduard Kabasakalyan, Karapet Davtyan, Viktorya Cholakyans, Alvard Mirzoyan, Karine Kentenyants, Diana Petrosyan, Armen Hayrapetyan, Himanshu A Gupte

“… Introduction: In 2013, the National Tuberculosis (TB) Program of Armenia introduced GeneXpert MTB/RIF (Xpert) assay to address World Health Organization (WHO) target of 80% (2020) of notified new and relapse TB cases to be tested with WHO recommended rapid diagnostic methods. …”
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Quantitative and qualitative gait assessments in Parkinson’s disease patients by Đurić-Jovičić Milica D., Jovičić Nenad S., Radovanović Saša M., Kresojević Nikola D., Kostić Vladimir S., Popović Mirjana B.

“…Objective gait assessment and monitoring progress of the disease can give clinicians and therapist important information about changes in gait pattern and potential gait deviations, in order to prevent concomitant falls. …”
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Predictive value of inflammatory regulators TGFb1 and CXCL8 in tumor tissue in colorectal cancer by I. A. Bogomolova, D. R. Dolgova, I. I. Antoneeva, T. V. Abakumova, I. R. Myagdieva, A. B. Peskov, T. P. Gening

“…Patients were divided into 3 groups: group I included patients without relapse of the disease, group II encompassed patients with relapse of the disease (within 6–16 months after the end of chemotherapy), group III included patients with disease progression. Expression of TGFb1 and CXCL8 in the tumor tissue before treatment in patients with stage II–III colorectal cancer (n = 77) was determined using quantitative realtime polymerase chain reaction (PCR) on the Bio-Rad CFX-96 Touch Real-Time PCR Detection System (USA). …”
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Impact of breast cancer awareness program on breast screening utilization among women in the United Arab Emirates: A cross-sectional study by Raseena Aboobacker Abdulla, Nafeesa Abdul Kareem, Rifah Anwar Assadi, Afreen Abdul Rahim Sanaullah, Sathyapriya Nandagopal, Shahnaz Mohamed Wazil, Jayakumary Muttappallymyalil

“…This research was conducted to assess the impact of breast cancer awareness programs on breast screening utilization among women in the United Arab Emirates. …”
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Estimated cost-effectiveness of sequential screening for colorectal cancer: evidence from the largest province-wide colorectal cancer screening program in China by Juan Zhu, Bingjie Jiang, Ruyi Xia, Chen Zhu, Weimiao Wu, Lingbin Du

“…The outcomes included colonoscopy participation rates, costs and yield (detection rate, colonoscopies to detect one lesion, and yield per 10,000 invitees). …”
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An interpretable machine learning model based on computed tomography radiomics for predicting programmed death ligand 1 expression status in gastric cancer by Lihuan Dai, Jinxue Yin, Xin Xin, Chun Yao, Yongfang Tang, Xiaohong Xia, Yuanlin Chen, Shuying Lai, Guoliang Lu, Jie Huang, Purong Zhang, Jiansheng Li, Xiangguang Chen, Xi Zhong

“…Abstract Background Programmed death ligand 1 (PD-L1) expression status, closely related to immunotherapy outcomes, is a reliable biomarker for screening patients who may benefit from immunotherapy. …”
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