Exploring the role of methylation-driven gene IFFO1 in pancreatic adenocarcinoma diagnosis, prognosis and cellular functions by XU Ziqi, HU Ruizhi, LI Junjian, WANG Hongxia, SANG Youzhou

“…Immunohistochemistry staining (IHC) was utilized to detect the expression of IFFO1 in cancer tissues and corresponding adjacent tissues from 27 PAAD patients. …”
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Phenolic Acid Investigation and In Vitro Antioxidant and Antiacetylcholinesterase Potentials of <i>Galeopsis</i> spp. (<i>Lamiaceae</i>) from Romanian Flora by Roxana Maria Golu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Adina-Elena Segneanu, Andrei Biţă, Antonia Radu, Adriana Cosmina Tîrnă, Maria Viorica Ciocîlteu, George Dan Mogoşanu, Johny Neamţu, Oana Elena Nicolaescu

“…AChE inhibition activity increased progressively from the roots to aerial parts to leaves, with leaves consistently exhibiting the strongest inhibitory effects across all <i>Galeopsis</i> spp. …”
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Comparative characteristics of endocrine profile in males with infertility as well as in adolescents with varicocele by S. V. Pichugova

“…Adolescents with varicocele taking into consideration progressive course of the disease and verified lower testosterone level require further monitoring of hormone level to prevent endocrine infertility.…”
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Diagnostic significance of soluble adhesion molecules and costimulatory molecules of immune cells in the patients with ischemic heart disease by A. V. Logatkina, I. V. Terekhov, S. S. Bondar, V. S. Nikiforov

“…Ischemic heart disease (IHD) represents significant medical issues, due to high prevalence of the disorder, permanent progressive course, being a leading cause of mortality. …”
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Uncovering the role of Gpr45 in obesity regulation by Eva O. Karolczak, Chia Li, Ivan C. Alcantara, Isabel M. Cohen, Claire Gao, Cuiying Xiao, Abigail I. Goldschmidt, Cynthia A. Pinkus, Junjie Li, Monica M. Li, Ryan M. Esquejo, Jean-Philippe Fortin, Kendra K. Bence, Marc L. Reitman, Michael J. Krashes

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Safety of creatine supplementation: a scientometrics analysis on the impact of the ‘Creatine For Health’ initiative and introduction to CREAS by Diego A. Bonilla, Drew E. Gonzalez, Gustavo Humeres, Jisun Chun, Kelly Hines, Adriana Gil, Richard B. Kreider

“…A big data text analysis was performed using the YouTube API v3 and the Twitter/X API v2, authorized under the X Academic Research program (Project name: “Creatine Safety” – APP ID: 21590870). …”
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A study on toxicity, local irritative effect of and allergic response to a novel intranasal medication containing N-phenylacetyl-L-prolylglycine ethyl ester by B. S. Burlaka, I. F. Bielenichev

“…Results were statistically processed by means of the standard statistical package of the licensed program Statistica for Windows 13 (StatSoft Inc., № JPZ804I382130ARCN10-J). …”
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IL-19 as a promising theranostic target to reprogram the glioblastoma immunosuppressive microenvironment by Gilbert Aaron Lee, Justin Bo-Kai Hsu, Yu-Wei Chang, Li-Chun Hsieh, Yi-Tien Li, Ying Chieh Wu, Cheng-Ying Chu, Yung-Hsiao Chiang, Wan-Yuo Guo, Chih-Chun Wu, Liang-Wei Chen, Hung-Wen Kao, Wan-Li Lin, Li‑Wen Tseng, Ting-Wei Weng, Duen-Pang Kuo, Sho-Jen Cheng, Yung-Chieh Chen, Shiu-Wen Huang, Hsing-Jien Kung, Cheng-Yu Chen

“…Blocking IL-19 significantly inhibited tumor progression of both TMZ-sensitive (TMZ-S) and TMZ-resistant (TMZ-R) GBM-bearing mice, and modulated the immune response within the GBM microenvironment. …”
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Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway by DanDan Liu, Hui Wang, Jialong Li, Siqi Sheng, Shu Wang, Ye Tian

“…Intracellular reactive oxygen species (ROS) levels were detected using DCFH-DA probe. Immunofluorescence was also used to observe the expression of α-SMA and E-cadherin in cells. …”
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The efficacy and safety of Ginkgo biloba L. leaves extract combined with ACEI/ARB on diabetic kidney disease: a systematic review and meta-analysis of 41 randomized controlled tria... by Zehua Zhang, Shiyun Tang, Shiyu Liu, Yulin Leng, Xiaoxu Fu, Hongyan Xie, Hong Gao, Hong Gao, Chunguang Xie, Chunguang Xie

“…No significant difference was detected in adverse events.ConclusionCombining GBE with ACEI/ARB may improve UAER, SCr, BUN, 24hUTP, Cys-C, TC, TG, LDL-C, hematocrit and fibrinogen in DKD patients. …”
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EFFECTS OF SYNTHETIC DISEASE-MODIFYING ANTIRHEUMATIC DRUGS, BIOLOGICAL AGENTS, AND PSYCHOPHARMACOTHERAPY ON THE MENTAL DISORDERS IN PATIENTS WITH RHEUMATOID ARTHRITIS by A. A. Abramkin, T. A. Lisitsyna, D. Yu. Veltishchev, O. F. Seravina, O. B. Kovalevskaya, E. L. Nasonov

“…At the study inclusion stage, ADS disorders were detected in 123 (96.1%) patients; CI was found in 88 (68.7%). …”
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Predictors of uveitic macular edema and functional prognostic outcomes: real-life data from the international AIDA Network uveitis registry by Jurgen Sota, Germán Mejía-Salgado, Silvana Guerriero, Gaafar Ragab, Gaafar Ragab, Stefania Costi, Maria Pia Paroli, Andrea Hinojosa-Azaola, Giuseppe Lopalco, Luciana Breda, Henrique Ayres Mayrink Giardini, Alex Fonollosa, Maria Sole Chimenti, Antonio Vitale, Carla Gaggiano, Blanca Aguilar-Barrera, Laura Daniela Rodríguez-Camelo, Guillermo Arturo Guaracha-Basañez, Mohamed Tharwat Hegazy, Mohamed Tharwat Hegazy, Rosanna Dammacco, Valeria Albano, Eduardo Martín-Nares, Santiago Espinosa-Lugo, Mahmoud Ghanema, Maria Morrone, Saverio La Bella, Rafael Alves Cordeiro, Francesco Carubbi, Alessandro Conforti, Piero Ruscitti, Ibrahim AlMaglouth, Rosaria Talarico, Stefano Gentileschi, Petros P. Sfikakis, Valeria Caggiano, Matteo Piga, Adele Civino, Francesca Ricci, Maissa Thabet, Marcello Govoni, Abdurrahman Tufan, Francesca Crisafulli, Jessica Sbalchiero, Sulaiman M. Al-Mayouf, Angela Mauro, Angela Mauro, Soad Hashad, Soad Hashad, Francesca Minoia, Alma Nunzia Olivieri, Samar Tharwat, Samar Tharwat, Maria Cristina Maggio, Abdelhfeez Moshrif, Gian Domenico Sebastiani, Daniela Opris-Belinski, Gülen Hatemi, Gülen Hatemi, Haner Direskeneli, Fatma Alibaz-Öner, Lampros Fotis, José Hernández-Rodríguez, Giovanni Conti, Piercarlo Sarzi Puttini, Ombretta Viapiana, Annarita Giardina, Patrizia Barone, Kalpana Babu, Rana Hussein Amin, Perla Ayumi Kawakami-Campos, Vishali Gupta, Annamaria Iagnocco, Ali Şahin, Antonella Insalaco, Andrés González-García, Ezgi Deniz Batu, Ester Carreño, Emanuela Del Giudice, Cecilia Beatrice Chighizola, Cecilia Beatrice Chighizola, Fabrizio Conti, Alberto Balistreri, Bruno Frediani, Luca Cantarini, Alejandra de-la-Torre, Claudia Fabiani

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The effect of Plant Growth Promoting Rhizohacteria on activities of antioxidative enzymes, physiological characteristics and root growth of four chickpea (Cicer arietinum L.) culti... by Rahim Naseri, Abbas Soleymani Fard, Amir Mirzaei, Fereshteh Darabi, Amin Fathi

“…The data were analyzed statistically by SAS program and the data means were compared by Duncan's multiple range test (DMRT).   …”
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Differences in endogenous hormones levels and mineral nutrient contents between seedy and seedless Orah mandarins during the flower and fruit abscission stages by DONG Jianmei, LI Jing, YANG Di, LI Jinxue, LAI Xinpu, LIU Hongming, FU Xiaomeng, YANG Hongxia, DU Yuxia

“…The (Zr+GA3+IAA)/ABA ratio demonstrated a progressive increase in leaves, flowers and fruits. …”
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Preclinical gout is common in the patient with stage 3–5 chronic kidney disease. Relevance of musculoskeletal ultrasound by Enrique Calvo-Aranda, Laura Barrio Nogal, Boris Anthony Blanco Caceres, Diana Peiteado, Marta Novella-Navarro, Eugenio De Miguel, Jaime Arroyo Palomo, Roberto Alcázar Arroyo, Juan Antonio Martín Navarro, Milagros Fernandez Lucas, Martha Elizabeth Diaz Dominguez, Marco Antonio Vaca Gallardo, Elda Besada Estevez, Leticia Lojo Oliveira

“…This will probably contribute to slowing down the progression of this pathology, which makes it essential to promote collaboration between Nephrology and Rheumatology. …”
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Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids by Amy R. Bentley, Michael R. Brown, Solomon K. Musani, Karen L. Schwander, Thomas W. Winkler, Mario Sims, Tuomas O. Kilpeläinen, Hugues Aschard, Traci M. Bartz, Lawrence F. Bielak, Jin-Fang Chai, Kumaraswamy Naidu Chitrala, Nora Franceschini, Mariaelisa Graff, Xiuqing Guo, Fernando P. Hartwig, Andrea R.V.R. Horimoto, Elise Lim, Yongmei Liu, Alisa K. Manning, Ilja M. Nolte, Raymond Noordam, Melissa A. Richard, Albert V. Smith, Yun Ju Sung, Dina Vojinovic, Rujia Wang, Yujie Wang, Mary F. Feitosa, Sarah E. Harris, Leo-Pekka Lyytikäinen, Giorgio Pistis, Rainer Rauramaa, Peter J. van der Most, Erin Ware, Stefan Weiss, Wanqing Wen, Lisa R. Yanek, Dan E. Arking, Donna K. Arnett, Christie Ballantyne, Eric Boerwinkle, Yii-Der Ida Chen, Martha L. Daviglus, Lisa de las Fuentes, Paul S. de Vries, Joseph A. C. Delaney, Amanda M. Fretts, Lynette Ekunwe, Jessica D. Faul, Linda C. Gallo, Sami Heikkinen, Georg Homuth, M. Arfan Ikram, Carmen R. Isasi, Jost Bruno Jonas, Liisa Keltikangas-Järvinen, Pirjo Komulainen, Aldi T. Kraja, Jose E. Krieger, Lenore Launer, Lifelines Cohort Study, Jianjun Liu, Kurt Lohman, Annemarie I. Luik, Ani W. Manichaikul, Pedro Marques-Vidal, Yuri Milaneschi, Stanford E. Mwasongwe, Jeffrey R. O’Connell, Kenneth Rice, Stephen S. Rich, Pamela J. Schreiner, Lars Schwettmann, James M. Shikany, Xiao-ou Shu, Jennifer A. Smith, Harold Snieder, Nona Sotoodehnia, E. Shyong Tai, Kent D. Taylor, Lesley Tinker, Michael Y. Tsai, André G. Uitterlinden, Cornelia M. van Duijn, Diana van Heemst, Melanie Waldenberger, Robert B. Wallace, Hwee-Lin Wee, David R. Weir, Wen-Bin Wei, Ko Willems van Dijk, Gregory Wilson, Jie Yao, Kristin L. Young, Xiaoyu Zhang, Wei Zhao, Xiaofeng Zhu, Alan B. Zonderman, Ian J. Deary, Christian Gieger, Hans Jörgen Grabe, Timo A. Lakka, Terho Lehtimäki, Albertine J. Oldehinkel, Martin Preisig, Ya-Xing Wang, Wei Zheng, Michele K. Evans, Michael Province, James Gauderman, Vilmundur Gudnason, Catharina A. Hartman, Bernardo L. Horta, Sharon L. R. Kardia, Charles Kooperberg, Ching-Ti Liu, Dennis O. Mook-Kanamori, Brenda WJH Penninx, Alexandre C. Pereira, Patricia A. Peyser, Bruce M. Psaty, Jerome I. Rotter, Xueling Sim, Kari E. North, Dabeeru C. Rao, Laura Bierut, Clint L. Miller, Alanna C. Morrison, Charles N. Rotimi, Myriam Fornage, Ervin R. Fox

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VULVAR AND VAGINAL GRAFT VERSUS HOST DISEASE IN A PATIENT WITH CHRONIC PHASE CHRONIC MYELOID LEUKEMIA AFTER ALLOGENEIC STEM CELL TRANSPLANTATION by Esra Pirinççi, M. Orhan Ayyıldız, Abdullah Karakuş, Reyhan Gündüz

“…In our patient, this condition was detected approximately 5 years after allogeneic transplantation. …”
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Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT by Graham Devereux, Seonaidh Cotton, Mintu Nath, Nicola McMeekin, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Amanda Lee, Graeme MacLennan, Alyn Morice, John Norrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Olivia Wu, Brian Lipworth

“…The progressive airflow limitation impacts the quality of life and is associated with increasing disability and morbidity, and premature mortality. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Main outcome measures The primary outcome was diagnostic model sensitivity and specificity for detecting bladder outlet obstruction, detrusor underactivity and detrusor overactivity, with 75.0% considered minimum clinically useful performance. …”
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Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial by Hamish McAllister-Williams, Nicola Goudie, Lumbini Azim, Victoria Bartle, Michael Berger, Chrissie Butcher, Thomas Chadwick, Emily Clare, Paul Courtney, Lyndsey Dixon, Nichola Duffelen, Tony Fouweather, William Gann, John Geddes, Sumeet Gupta, Beth Hall, Timea Helter, Paul Hindmarch, Eva-Maria Holstein, Ward Lawrence, Phil Mawson, Iain McKinnon, Adam Milne, Aisling Molloy, Abigail Moore, Richard Morriss, Anisha Nakulan, Judit Simon, Daniel Smith, Bryony Stokes-Crossley, Paul Stokes, Andrew Swain, Zoë Walmsley, Christopher Weetman, Allan H Young, Stuart Watson

“…Results Fifty-one participants were recruited to pre-randomisation of whom 39 progressed to randomisation (dropout rate = 24%). Completion rates for self-rated online scales were around 80%. …”
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