SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer by Xudong Li, Jingjing Ge, Mengdi Wan, Tongtong Feng, Xiaoqian Li, Haibo Zhang, Zhangyan Wang, Yongsheng Gao, Meiting Chen, Fei Pan

“…RNA-Seq analysis indicated that FAO might be implicated in SLC31A1-mediated breast cancer progression. CPT1A was also overexpressed in TAM-resistant breast cancer cells, accompanied by enhanced FAO rates and ATP levels. …”
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Proaterogenic disorders of lipid and carbohydrate metabolism in chronic kidney disease nondiabetic origin by T. N. Solomenchuk, H. V Semegen-Bodak

“…LDL-cholesterol level (mmol/l) increased with the progression of renal dysfunction: from 3,32±0,21 (1st) and 3,77±0,34 (2nd) to 4,12±0,44 (3rd), which was significantly higher than in controls (p<0,001). …”
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Association between herbicide exposure and liver enzyme levels in a middle-aged and elderly population by Weiya LI, Zhuoya ZHAO, Xu CHENG, Jun AN, Shiyang ZHANG, Chengyong JIA, Meian HE

“…The linear regression analysis showed that the changes in AST increased progressively over 5 years in the second, third, and fourth quartiles of propham compared to the lowest quartile group (the second quartile: b=1.49, 95%CI: 0.10, 2.87; the third quartile: b=1.52, 95%CI: 0.14, 2.90; the fourth quartile: b=1.69, 95%CI: 0.31, 3.08; P <0.05). …”
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A Novel Retinal Nerve Fiber Layer Biomarker of Amyotrophic Lateral Sclerosis (ALS) Identified Using Longitudinal in vivo Ocular Imaging by Khorrami F, Gupta N, Zhou X, Liang Y, Yucel YH

“…We aim to assess the presence of inner retinal pathology in a mouse model of ALS and its possible progression with age.Methods: Transgenic SOD1G93A mice (n=8, 4M/4F) and age-matched controls (n=8, 4M/4F) underwent in vivo retinal imaging with confocal scanning laser ophthalmoscopy (cSLO) coupled with optical coherence tomography (OCT) at 20 weeks of age. …”
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Integrated Early CRP Kinetics and Plasma EBV DNA Clearance as Prognostic Biomarkers in De Novo Metastatic Nasopharyngeal Carcinoma Treated with First-Line Chemoimmunotherapy by Fang M, Hu Y, Wang T, Su Y, Lu T, Zhang H, Li J, Xie C, Gong X

“…Associations with objective response rate (ORR), and progression-free survival (PFS) were evaluated.Results: The multicenter study included 149 patients with dmNPC (median follow-up: 22 months). …”
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Lung cancer-associated fibroblasts-mediated collagen deposition drives mediastinal lymph node metastasis in non-small cell lung cancer by Caoyang Chen, Caoyang Chen, Yuqian Feng, Yuqian Feng, Frankie Chi Fat Ko, Sze Kwan Lam, Sheng Yan, James Chung Man Ho

“…Cancer-associated fibroblasts (CAFs) within the tumor microenvironment (TME) play a crucial role in tumor progression by promoting growth and invasion. However, the specific contributions of lung CAFs to mediastinal lymph node metastasis in NSCLC remain poorly understood. …”
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FACTORS ASSOCIATED WITH HEARING IMPAIRMENT IN INFANTS WHO RECEIVED THERAPEUTIC HYPOTHERMIA by М. Соломенко, О. Харитонова

“…Exclusion criteria encompassed: gestational age <35 weeks, congenital malformations, confirmed genetic abnormalities, progressive obstructive ventriculomegaly, previous central nervous system infections, and neonatal hemolytic disease. …”
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A Novel Hypoxia-Related Gene Signature with Strong Predicting Ability in Non-Small-Cell Lung Cancer Identified by Comprehensive Profiling by Huajun Yang, Zhongan Wang, Ling Gong, Guichuan Huang, Daigang Chen, Xiaoping Li, Fei Du, Jiang Lin, Xueyi Yang

“…The interaction between DEGs and the competing endogenous RNAs (ceRNA) network was detected using STRING and visualized using Cytoscape. …”
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Diversity of <i>Cytauxzoon</i> spp. (Piroplasmida: Theileriidae) in Wild Felids from Brazil and Argentina by Ana Cláudia Calchi, Joares A. May-Júnior, Vinícius Baggio-Souza, Laura Berger, Renata Fagundes-Moreira, Rafaela Mallmann-Bohn, Laíza de Queiroz Viana Braga, Murillo Daparé Kirnew, Matheus Folgearini Silveira, Roberto Andres Navarrete Ampuero, Charlotte O. Moore, Ricardo Bassini-Silva, Heitor Miraglia Herrera, Edward Bealmear Breitschwerdt, Ricardo G. Maggi, Eduardo Eizirik, Rosangela Zacarias Machado, Fabiana Lopes Rocha, João Fabio Soares, Marcos Rogério André

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High spatial resolution crop type and land use land cover classification without labels: A framework using multi-temporal PlanetScope images and variational Bayesian Gaussian mixtu... by Minh Tri Le, Khuong H. Tran, Phuong D. Dao, Hesham El-Askary, Tuyen V. Ha, Taejin Park

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Relación entre la actividad física escolar y extraescolar en estudiantes de escuelas públicas chilenas (Relationship between school and out-of-school physical activity in Chilean... by Michelle Marambio Miranda, Tamara Núñez Fernández, Jaime Ramírez Guajardo, Pablo Ramírez Eyraud, Ximena Alejandra Palma Leal, Fernando Rodríguez-Rodríguez.

“…A contribution of physical education classes in combination with the sessions from comprehensive sports academies was detected regarding total practice, the average being 4.2, meaning that the category was “high level of physical activity”. …”
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Interleukin-4 and specific IgE to oranges levels study in persons with allergic anamnesis by A. S. Prilutskiy, N. B. Abylgazinova, K. Y. Tkachenko

“…Statistical analysis was performed using the licensed program “MedStat” (Donetsk, Ukraine). The median, the median error, the left and right limits of 95% confidence interval were calculated for all of three samples (IL-4, total IgE-Ab, sIgE-Ab). …”
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Silent Revolution in Research for Sustainability by Bruce Alder

“…Today’s world needs science in real-time, whether to detect drought, confront Ebola, or assist refugees. …”
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Аldosterone synthetase gene (CYP11B2) polymorphism and structural parameters of the left ventricle in patients with coronary heart disease, postinfarction cardiosclerosis by M. N. Dolzhenko, V. Ye. Dosenko, L. Ye. Lobach

“…Statistical analysis of the results was performed using Microsoft Excel, the statistical program SPSS (version 20, US). The results obtained are presented as M ± σ. …”
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Morphofunctional Characteristics of the Hippocampus of White Rats in the Acute Period After Severe Traumatic Brain Injury During the Use of L-lysine Aescinat by I. P. Koshman, A. Yu. Shoronova, S. S. Stepanov, A. G. Kalinichev, V. A. Akulinin, A. S. Stepanov, D. B. Avdeyev, V. L. Molchanova

“…The cytoskeleton of neurons was studied by detecting MAP-2, and astroglia by GFAP. On color raster images (staining with hematoxylin and eosin, x100) using the Find Maxima plug-in filter, the zones of maximum brightness were determined, which were then analyzed using Analyze Particles from the ImageJ 1.52s program. …”
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Laboratory Evaluation of the Platelet Component of Hemostasis in acute Coronary Syndrome With ST Segment Elevation by D. Markhulia, K. A. Popugaev, D. A. Sychev, M. V. Vatsik-Gorodetskaya, G. A. Gazaryan, M. A. Godkov, A. A. Kachanova, K. V. Kiselev, E. V. Klychnikova, D. A. Kosolapov, I. M. Kuzmina, K. B. Mirzaev, O. K. Popugaeva, S. N. Tuchkova

“…The following pharmacogenetic markers were determined in all patients: CYP2C19*17, CYP2C19*2, CYP2C19*3, SLCO1B1 , CYP3A5*3 . LOF alleles were detected in 32 patients (67%). Among them, in the group taking aspirin in combination with clopidogrel, three subgroups of patients were distinguished: 7 patients in the slow metabolizer (SM) subgroup, 8 patients in the general rapid metabolizer subgroup , and 8 patients without LOF alleles were designated as normal metabolizers. …”
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Prevalence of syphilis infection among migrant workers in Qatar: a nationwide cross-sectional survey by Hiam Chemaitelly, Houssein H Ayoub, Hanan F Abdul Rahim, Abdullatif Al Khal, Einas Al Kuwari, Roberto Bertollini, Peter Coyle, Andrew Jeremijenko, Anvar Hassan Kaleeckal, Gheyath K Nasrallah, Hadi M Yassine, Hamad Eid Al Romaihi, Mohammed H Al-Thani, Mohamed Ghaith Al-Kuwari, Asmaa A Al Thani, Ahmed Ismail Ahmed Ismail, Duaa W Al-Sadeq, Fathima H Amanullah, Jawaher A Al-Emadi, Hadiya M Khalid, Parveen B Nizamuddin, Ibrahim Al-Shaar, Ibrahim W Karimeh, Mutaz M Ali, Sami Abdeen, Ashraf Abdelkarim, Faisal Daraan, Ahmed Ibrahim Hashim Elhaj Ismail, Nahid Mostafa, Mohamed Sahl, Jinan Suliman, Elias Tayar, Hasan Ali Kasem, Meynard J A Agsalog, Bassam K Akkarathodiyil, Ayat A Alkhalaf, Mohamed Morhaf M H Alakshar, Abdulsalam Ali A H Al-Qahtani, Monther H A Al-Shedifat, Anas Ansari, Ahmad Ali Ataalla, Sandeep Chougule, Abhilash K K V Gopinathan, Feroz J Poolakundan, Sanjay U Ranbhise, Saed M A Saefan, Mohamed M Thaivalappil, Abubacker S Thoyalil, Inayath M Umar, Odette Chaghoury, Elmoubasher Farag

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The burden of a new coronavirus infection in a Children’s multidisciplinary hospital in St. Petersburg 2020–2021 by E. A. Dondurei, V. А. Kondratev, L. N. Isankina, N. Yu. Kaika, Yu. A. Gaist, V. V. Yesikov, I. M. Kosenko, V. A. Kaziakhmedov, K. V. Pshenisnov, O. V. Zabirova, S. I. Dvorak, L. V. Ivanova, O. O. Osipova, O. I. Afanasyeva, D. A. Lioznov

“…All severe cases of COVID-19 in children require a personalized approach, taking into account the existing background diseases and possible options for the progression of the process. MIS-C should be considered as a systemic inflammatory response syndrome within the framework of an infectious disease of various etiologies, differentiated with Kawasaki disease and the debut of systemic diseases. …”
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Interpersonal counselling for adolescent depression delivered by youth mental health workers without core professional training: the ICALM feasibility RCT by Jon Wilson, Viktoria Cestaro, Eirini Charami-Roupa, Timothy Clarke, Aoife Dunne, Brioney Gee, Sharon Jarrett, Thando Katangwe-Chigamba, Andrew Laphan, Susie McIvor, Richard Meiser-Stedman, Jamie Murdoch, Thomas Rhodes, Carys Seeley, Lee Shepstone, David Turner, Paul Wilkinson

“…Results Feasibility outcomes did not meet the estimated progression criteria. Despite efforts to increase referrals, the 80% recruitment rate was not achieved. …”
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Effects of direct moxibustion on antigen-presenting cells in gastric tissue of rat models with gastric cancer: Understanding the immunological mechanisms by Tian-yu GAO, Fei-cheng ZHANG, Ru-fang PAN, Shu-ya MA, Xiao-qi ZHANG, Li-jia PAN, Chun-sheng JIA

“…Conclusion: Direct moxibustion alleviates the pathological progression of gastric cancer in an MNNG-induced rat model. …”
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