Assessment of Subclinical Manifestations of Atherosclerosis of Coronary and Peripheral Arteries and Bone Strength Parameters in Women by I. A. Skripnikova, M. A. Kolchina, O. V. Kosmatova, M. A. Myagkova, V. E. Novikov, O. Yu. Isaykina, O. M. Drapkina

“…A decrease in BMD and an increase in the marker of bone resorption, associated with an increase in indices of vascular stiffness and subclinical atherosclerosis and, especially, CA calcification, allows us to think about the common mechanisms of development and progression of atherosclerosis and osteoporosis. Therefore, early examination of women with a high cardiovascular risk, assessed by the SCORE scale, after 45 years and before menopause to detect vascular rigidity and the presence of subclinical atherosclerosis, and performing x-ray densitometry for individuals with changes in these indices will allow stratify the risks of atherosclerosis and osteoporosis complications and recommend preventive use of drugs that reduce vascular rigidity and increase BMD.…”
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Ductular reaction or hepatic reparative complex: immunohistochemical features in liver cirrhosis in patients with chronic hepatitis by V. A. Tumanskiy, S. V. Fen’

“…The ductular reaction can be detected in the active phase with maximum manifestations in patients with liver cirrhosis on the background of chronic hepatitis, it may have an average or weak degree of severity; in a significant number of patients, the effects of the ductular reaction of the liver are revealed. …”
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Myofibrillogenesis Regulator-1 in Smooth Muscle Cells Modulates Inflammation Signaling Pathways via Regulating ROCK1 Ubiquitination and Degradation to Impact Aortic Dissection [Cor... by Yin H, Li X, Lu D, Zhao X, Yang Z, Wang Z, Xu F, Chen Y, Li C

“…Figure 5 MR-1 Affects AD Progression by Regulating the ROCK1-NF-kappaB p65 Signaling Pathway. …”
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Early infantile epileptic encephalopathy type 16: the new clinical and genetic variant of TBC1D24 gene mutation by A. A. Kholin, I. D. Fedonyuk, O. P. Dovelman, N. N. Zavadenko, T. V. Kozhanova, E. A. Kholina, G. Sh. Khondkarian, E. S. Il`ina

“…This clinical case is closer to progressive myoclonic epilepsy with dystonia (PMED), which indicates the nosological autonomy of this form of epilepsy.Сonclusion. …”
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A MULTICENTER, BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY OF THE SYMPTOM- AND STRUCTURE-MODIFYING EFFET OF ALFLUTOP IN PATIENTS WITH KNEE OSTEOARTHRITIS. REPORT 2: THE ASSESSMENT... by L. I. Alekseeva, E. P. Sharapova, E. A. Taskina, N. V. Chichasova, G. R. Imametdinova, N. A. Shostak, N. G. Pravdyuk, L. N. Denisov

“…Alflutop delays the radiographic progression of knee OA, joint space narrowing and osteophyte growth, and reduces the degradation of the articular cartilage matrix.…”
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Coniferaldehyde reverses 3-nitropropionic acid-induced Huntington’s disease pathologies via PKM2 restoration and JAK2/STAT3 inhibition by Ayooluwa Gabriel Ibiayo, Peeraporn Varinthra, Mukundan Nagarajan, Ingrid Y Liu

“…Abstract Background Huntington’s disease (HD) is a fatal neurodegenerative disorder characterized by progressive motor decline and neuronal loss, with no curative disease-modifying therapies available. …”
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The Analysis of Paratuberculosis Prevalence and Associated Performance Parameters in Dairy Cows from Xi’an City by Xuejian Zhao, Qiang Liang, Haipeng Feng, Caixia Ru, Lei Wang, Kang Zhang, Jianxi Li

“…It was also found that the paratuberculosis prevalence among dairy cows increased progressively with the increase in parity until the fifth calving, after which a significant decline was observed. …”
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Case of granulomatosis with polyangiitis: optimal possibilities for rapid diagnosis in a multidisciplinary hospital by A. V. Novikova, N. G. Pravdyuk, E. I. Shmidt, A. P. Raksha, M. R. Mazra, A. R. Yunyaev, J. S. Zhulina

“…According to the radiography (RG) of the chest organs, right-sided pneumonia was detected. Conducted antibiotic therapy without effect. …”
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Structural and Functional Reorganization of the Sensorimotor Cortex During Ligation of the Common Carotid Arteries (Experimental Study) by L. M. Makarieva, V. A. Akulinin, M. S. Korzhuk, S. S. Stepanov, A. Y. Shoronova, D. B. Avdeev, I. G. Tsuskman

“…The number of NSE-positive neurons in layer V of the SMC progressively decreased throughout the whole study period. …”
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Integrating advanced analytical methods to assess epigenetic marks affecting response to hypomethylating agents in higher risk myelodysplastic syndrome by Theodoros Nikolopoulos, Eleftherios Bochalis, Theodora Chatzilygeroudi, Vasiliki Chondrou, Irene Dereki, Katerina Athanasopoulou, John Zafeiropoulos, Kyriakos Bourikas, George P. Patrinos, Argiris Symeonidis, Argyro Sgourou

“…The 5hmdC epigenetic mark was approximately detected at 37.5–40% among NRs and Rs, implying the impairment of the natural active demethylation pathway, mediated by the ten-eleven (TET) 5mdC dioxygenases. …”
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Resveratrol contributes to NK cell-mediated breast cancer cytotoxicity by upregulating ULBP2 through miR-17-5p downmodulation and activation of MINK1/JNK/c-Jun signaling by Bisha Ding, Jie Li, Jia-Lin Yan, Chun-Yan Jiang, Ling-Bo Qian, Jie Pan

“…This finding identifies RES as a potentially effective therapeutic agent for inhibiting BC progression and optimizing NK cell-based cancer immunotherapy.…”
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Inhibition of cc chemokine receptor 10 ameliorates osteoarthritis via inhibition of the phosphoinositide-3-kinase/Akt/mammalian target of rapamycin pathway by Yan Luo, Feng Zhou, Xiaojing Wang, Runwei Yang, Yi Li, Xiaochun Wu, Bin Ye

“…Abstract Background Osteoarthritis (OA) is a joint disease characterized by inflammation and progressive cartilage degradation. Chondrocyte apoptosis is the most common pathological feature of OA. …”
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Genetic characteristics analysis of influenza A(H1N1) virus in Jiaxing, China, in the postepidemic era by Yin Song, Xue Zhang, Jimei Ji, Lina Li, Yamei Zhou, Ganglin Ren, Shencong Lv, Xiaofei Zhang, Yong Yan, Guoying Zhu

“…Abstract Background Following the lifting of COVID-19 pandemic control measures, a progressive increase in influenza A virus activity, particularly the H1N1 subtype, has been observed in Jiaxing. …”
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Randomized, observer-blind, controlled Phase 1 study of the safety and immunogenicity of the Na-GST-1/Alhydrogel hookworm vaccine with or without a CpG ODN adjuvant in hookworm-naï... by David J Diemert, Maria Zumer, Mark Bova, Christina Gibbs-Tewary, Elissa M Malkin, Doreen Campbell, Lara Hoeweler, Guangzhao Li, Maria Elena Bottazzi, Peter J Hotez, Jeffrey M Bethony

“…In each cohort of 12 participants, 4 were randomized to receive 100 µg of Na-GST-1/Alhydrogel and 8 to receive 30 µg or 100 µg of Na-GST-1/Alhydrogel plus the Cytosine-phospho-Guanine (CpG) oligodeoxynucleotide Toll-like receptor-9 agonist, CpG 10104, in the first and second cohorts, respectively. Progression to the second cohort was dependent upon evaluation of 7-day safety data after all participants in the first cohort had received the first dose of vaccine. …”
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Dinámica de la latencia en semillas de Brachiaria dictyoneura (Fig & Not) stapf cv llanero by López Y., Ferguson J. E., Sánchez Manuel Salvador

“…In contrast, acid-scarified spikekelets showed a progressive decrease of dormancy with time, reaching a minimum value at six months after harvest. …”
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Associations among IL-6 Signaling Molecules in Treg Populations in Patients with Relapsing-Remitting Multiple Sclerosis by Magdalena Kierasińska, Maja Machcińska, Marta Maruszewska-Cheruiyot, Ludmiła Szewczak, Anna Karlińska, Rafał Rola, Michael Stear, Katarzyna Donskow-Łysoniewska

“…Background: Peripheral immune cells participate in the pathogenesis and progression of central nervous system diseases including relapsing-remitting multiple sclerosis (RRMS), which is an immune-mediated demyelinating disorder. …”
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THE INTENSITY OF EMOTIONAL TENSION IN CHILDREN WITH CLEFT PALATE IN RESPONSE TO SITUATIONAL STRESS by P. I. Tkachenko, N.M. Lokhmatova, S.A. Byеlokon, V.A. Dobroskok

“…Comparative analysis of the indices, particularly, the systolic and diastolic pressure, Hildebrandt’s coefficient and minute volume (р>0,05), obtained during the examination of children at the out-patient reception hours and at the hospital showed its progressive increase while staying at atypical psycho-emotional atmosphere of the Surgical Unit. …”
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Molecular characterization of methicillin-susceptible/resistant Staphylococcus aureus from bloodstream infections in northern Japan: The dominance of CC1-MRSA-IV, the emergence of... by Meiji Soe Aung, Masako Osada, Noriko Urushibara, Mitsuyo Kawaguchiya, Nobuhide Ohashi, Mina Hirose, Masahiko Ito, Kazuki Yamada, Kousuke Tada, Nobumichi Kobayashi

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Association of Escherichia coli pathotypes with fecal markers of enteropathy and nutritional status among underweight adults in Bangladesh by Rahvia Alam Sthity, Md. Zahidul Islam, Md. Ehsanul Kabir Sagar, Md. Amran Gazi, Md. Amran Gazi, Jafrin Ferdous, Md. Mamun Kabir, Mustafa Mahfuz, Tahmeed Ahmed, Tahmeed Ahmed, Ishita Mostafa, Ishita Mostafa

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Deletional Alpha-Thalassemia Alleles in Amazon Blood Donors by Fernanda Cozendey Anselmo, Natália Santos Ferreira, Adolfo José da Mota, Marilda de Souza Gonçalves, Sérgio Roberto Lopes Albuquerque, Nelson Abrahim Fraiji, Ana Carla Dantas Ferreira, José Pereira de Moura Neto

“…Alpha-thalassemia-23.7kb deletion was the most common allele detected in Manaus blood donors, which is a consistent result, once it is the most common type of α-thalassemia found throughout the world. …”
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