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12441
Sex-specific trunk movement coordination in participants with low-back pain and asymptomatic controls
Published 2025-04-01“…Pain chronicity had an effect on trunk dynamic stability (i.e., increased trunk instability), while no effects of sex and pain intensity were detected in trunk dynamic stability and movement variability.ConclusionsLow-back pain intensity and chronicity was not associated with lumbo-pelvic posture and kinematics, indicating that lumbo-pelvic posture and kinematics during a trunk flexion movement have limited practicality in the clinical diagnosis and management of low-back pain. …”
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12442
Does the blood glucose control have an effect on the success of the painful diabetic neuropathy treatment?
Published 2018-01-01“…Even though the disturbance of glucose control is the key factor for the progression of PDN, it is not significant for the outcome of the pain treatment. …”
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12443
Gubi Decoction Ameliorates Porous Cartilage Endplate in an Intervertebral Disc Degeneration Model Mouse Through Inhibition of NF-κB Activity and Pyroptosis
Published 2025-04-01“…After 8 weeks of LSI modeling, the therapeutic efficacy on IVDD was evaluated through changes in lumbar spine function, histopathological morphology, extracellular matrix (ECM) metabolism, nucleus pulposus (NP) cell viability, and cartilage endplate (CEP) cell pyroptosis; at 4 weeks after modeling, the activation of NF-κB signaling was detected.Results: GBD can attenuate the progression of IVDD in mice, resulting in substantially increases disc height index (DHI) and NP matrix, reduced the degree of annulus fibrosus (AF) tear and the formation of cavity in CEP. …”
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12444
Sistem Identifikasi Penyakit Paru Obstruktif Kronik (PPOK) Berdasarkan Suara Paru-Paru Menggunakan Jaringan Saraf Tiruan Berbasis Raspberry Pi
Published 2023-02-01“…This system works by detecting whether the sound of the lungs is COPD infected or healthy. …”
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12445
Spi1 aggravates neuropathic pain by modulating Clec7a-mediated neuroinflammation and microglial phagocytosis
Published 2025-07-01“…The spared nerve injury (SNI) mice and LPS induced BV2 cells were employed to detect the expression of Spi1. Silencing Spi1 was performed to determine their roles in SNI progression. …”
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12446
COMPETENZE CHIAVE PER IL CURRICOLO VERTICALE: L’OPINIONE DEGLI INSEGNANTI E I MATERIALI DIDATTICI
Published 2025-01-01“…Furthermore, in order to detect any references to the vertical development of the skills taken into consideration, some Italian textbooks used in the last year of primary school and the first year of secondary school were examined. …”
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12447
The effect of 1,25(OH)2D3 on Dickkopf-1 methylation in colorectal cancer
Published 2025-03-01“…A DKK1 expression plasmid was transfected into cells to assess the functional significance of DKK1 in CRC progression via CCK8, wound healing and migration assays. …”
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12448
AI-HOPE-TGFbeta: A Conversational AI Agent for Integrative Clinical and Genomic Analysis of TGF-β Pathway Alterations in Colorectal Cancer to Advance Precision Medicine
Published 2025-06-01“…The transforming growth factor-beta (TGF-β) signaling pathway plays a critical role in colorectal cancer (CRC) progression by mediating epithelial-to-mesenchymal transition (EMT), immune evasion, and metastasis. …”
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12449
THE CONTENT OF INTERLEUKINS IN ORAL FLUID OF PATIENTS WITH NON-REMOVABLE METAL CERAMIC PROSTHESES
Published 2018-12-01“…The IL-6 high level is a prognostic adverse factor, which can indicate the progression of the inflammatory process and the increase of membrane-destructive disorders in the cells. …”
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12450
S100a4 promotes metastatic transformation in non-metastatic liver cancer cells through NMIIa binding: mechanistic insights
Published 2025-07-01“…S100A4 may serve as a potential biomarker for predicting EMT occurrence, disease progression, and prognosis in HCC patients.…”
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12451
CHANGES IN THE DENTAL STATUS OF PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE
Published 2022-03-01“…The active participation of the dentist in the treatment of patients with internal diseases is essential for prevention of the progression or occurrence of complications in different somatic pathology, as well as for breaking the existing comorbid connection. …”
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12452
PIK3CA gene mutation status associated with poor prognosis of breast cancer: a retrospective cohort study
Published 2025-02-01“…Twenty mutations were detected, with 12 located in exon 20 and 8 in exon 9. …”
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12453
Ultrasonography for diagnosing medial sided ankle instability in supination external rotation ankle fracture
Published 2025-03-01“…Results Among all four loading conditions, all medial clear space values increased as the supination-external rotation ankle injury stage progressed (Spearman’s rank correlation ranged from 0.43 to 0.90, P <.001). …”
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12454
Occurrence of leprosy among patients with cutaneous leishmaniasis in a hyperendemic area for both diseases
Published 2025-03-01“…It is noteworthy that one infection may have a clinical impact on the progression of the other. However, follow-up studies are needed to further clarify these impacts. …”
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12455
Structural changes of the stromal and vascular components of n.tibialis in the case of diabetes mellitus
Published 2013-12-01“…The walls of the affected vessels were almost completely replaced by hyaline. Sclerosis progressed in endo-, peri- and epineurium of the lower segment, partial epineurium detachment was observed. …”
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12456
Molecular mechanism of DdSOC1 gene regulating flower bud initiation in Diospyros deyangensis
Published 2025-02-01“…As the flowering process progressed, SOC1 expression in the leaves rose. SOC1 expression in the buds peaked during the seedling stage and decreased during the flowering stage. …”
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12457
Worlds Next Door: A Candidate Giant Planet Imaged in the Habitable Zone of α Centauri A. II. Binary Star Modeling, Planet and Exozodi Search, and Sensitivity Analysis
Published 2025-01-01“…Additionally, postprocessing with the principal-component-analysis-based Karhunen–Loéve image processing algorithm reveals a point source, called S 1, in 2024 August, detected at signal-to-noise ratio of 4–6 (3.3–4.3 σ ), a projected separation of ≈1 $\mathop{.}…”
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12458
Myoglobin expression improves T-cell metabolism and antitumor effector function
Published 2025-06-01“…B16F10-gp33 tumor-bearing mice were additionally treated with anti-programmed cell death protein-1 (PD-1) checkpoint inhibitor.Results Here we demonstrate that expression of the oxygen-binding protein myoglobin in T cells can boost their mitochondrial and glycolytic metabolic functions. …”
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12459
EGFR and MUC1 as dual-TAA drug targets for lung cancer and colorectal cancer
Published 2024-11-01“…Expression of MUC1 and EGFR in tumors and normal tissues was detected by immunohistochemistry (IHC), bulk transcriptomic and single-cell transcriptomic analyses. …”
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12460
The role of imaging in defining cardiovascular risk to help cancer patient management: a scoping review
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