Constraints on ore vectoring from geochemical fingerprints of porphyry style pyrite by Beata Naglik, Artur Sosnal, Magdalena Dumańska-Słowik, Tomasz Toboła, Dimitrina Dimitrova, Ryszard Habryn, Paweł Derkowski, Zbigniew Czupyt, Maciej Woszczyna, Marek Markowiak, Jaroslav Pršek

“…. + 3.40‰) to distal zone (av. + 3.05 ‰) was detected only for late-stage pyrite. Both the temporal and lateral zonation of δ34Spyrite could be explained by the progressive temperature decrease of the mineralized system and the mixing of ore-forming solutions with more dilute meteoric waters. …”
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RNF213 governs divergent tumor-immune dynamics across human cancers: a prognostic biomarker for immunotherapy stratification by Jinpeng Wen, Zhekuan Lv, Mojiao Lu, Chuanming Zheng, Changtian Yin

“…Conclusion This study highlights RNF213’s dual functionality in tumor progression and immune modulation, underscoring its potential as both a prognostic biomarker and a therapeutic target. …”
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Aβ‐reactive T cell polyfunctionality response as a new biomarker for mild cognitive impairment by Yen‐Ling Chiu, Sui‐Hing Yan, Yang‐Teng Fan, Chiung‐Fang Chang, Ruo‐Wei Hung, Yi‐Chien Liu, TienYu Owen Yang, Yi‐Fang Chuang

“…Future studies are needed to determine the predictive role of amyloid‐reactive T cell responses in disease progression and if the amyloid‐reactive immune response could be a therapeutic target for the treatment of neurodegeneration.…”
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EGFR EXPRESSION IN RECTAL CANCER, RELATION TO THE FREAQUENCY OF LYMPH NODE METASTASIS by I. V. Stepanov, S. R. Altybaev, N. V. Krakhmal, К. V. Rachkovsky, D. A. Sorokin, S. G. Afanasyev, S. V. Vtorushin, М. V. Zavyalova

“…Thus, the expression and mutation of the EGFR gene is associated with various variants of tumor progression and an unfavorable prognosis for malignant tumors of various localizations. …”
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A novel mutation of ramR involved in tigecycline resistance in Klebsiella pneumoniae by Yuyao Xu, Qi Chen, Chenhao Zhao, Xin Ma, Lei Wang, Feinan Qian, Xiangyu Guan, Hong Du, Haifang Zhang

“…A novel two-base pair deletion mutation (position 517-518) in the ramR gene (g. 517_518 del) was identified in Klebsiella pneumoniae strains cultured in broth medium containing progressively increasing concentrations of tigecycline (4, 8, and 16 mg/L). …”
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Associations of dyadic appraisal of cancer cachexia symptoms with psychological distress and quality of life in dyads of palliative care patients: a longitudinal mixed-methods stud... by Huilin Cheng, Carmen Wai Lim Leung, Jeffrey Sheung Ching NG, Kam Hung Wong, Deepa Natarajan, Lut Ming Chan, Nancy Hiu Yim NG, Tsz Wai Tsang, Wai Ming Leung, Raymond See Kit LO

“…Abstract Background Cancer cachexia (CC) is a fatal syndrome most prevalent in palliative care patients and is typically characterized by a progressive increase in weight loss and anorexia. The inability to detect and accurately appraise CC symptoms early can lead to a delayed diagnosis of CC and late initiation of symptom management, subsequently resulting in shorter survival. …”
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Suppression of pseudogene MT2P1 transcription induced by E2F7 inhibits hepatocellular carcinoma cell proliferation and facilitates apoptosis via preserving its parental gene by Yiquan Lu, Yifan Zhang, Fengjie Hao, Nan Wang, Yongjun Chen, Junqing Wang

“…Their transcripts are mostly attributed to non-coding RNAs that play various functions in human tumorigenicity and progression. Distinctively, pseudogene MT2P1 is universally transcribed in hepatocytes and presents a significant decrease in hepatocellular carcinoma (HCC). …”
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Immediate Postoperative Insulin Requirements May Predict Metabolic Outcome after Total Pancreatectomy and Islet Autotransplantation by Neha Verma, Amer Rajab, Jill Buss, Luis Lara, Kyle Porter, Philip Hart, Darwin Conwell, W. Kenneth Washburn, Sylvester Black, Kristin Kuntz, Shumei Meng

“…Chronic pancreatitis (CP) is a progressive disease that leads to eventual loss of endocrine and exocrine function. …”
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Knockdown of KLF5 ameliorates renal fibrosis in MRL/lpr mice via inhibition of MX1 transcription by Shanshan Tao, Xiao Tan, Wen Chai, Xiaojie Peng, Weimin Zheng, Rui Fu, Meihui Deng

“…Abstract Objective This study aims to elucidate the role of Kruppel‐like factor (KLF5) and myxovirus resistance 1 (MX1) in the progression of renal fibrosis in lupus nephritis (LN). …”
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Response of Human Mesenchymal Stromal Cells from Periodontal Tissue to LPS Depends on the Purity but Not on the LPS Source by Christian Behm, Alice Blufstein, Setareh Younes Abhari, Christoph Koch, Johannes Gahn, Christina Schäffer, Andreas Moritz, Xiaohui Rausch-Fan, Oleh Andrukhov

“…Even a small amount of contaminating lipoproteins can drastically enhance the hPDLSCs’ and hGMSCs; responsiveness to P. gingivalis LPS, which might also contribute to the progression of periodontal disease.…”
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Cer(d18:1/16:0) as a biomarkers for acute coronary syndrome in Chinese populations by Liang Zhang, Yang Zhang, YaoDong Ding, Tong Jin, Yi Song, Lin Li, XiaoFang Wang, Yong Zeng

“…Abstract Ceramides play a crucial role in atherosclerosis progression and have been linked to cardiovascular events. …”
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Comprehensive Microbiological and Metagenomic Analysis of the Guillain–Barré Syndrome Outbreak in Lima, 2019 by Jesús D. Rojas, Mariana Ramos, Cristopher Cruz, Kyle A. Long, Logan J. Voegtly, Rina Meza, Nereyda Espinoza, Ana Ramos Ttito, Hugo Umeres Cáceres, Alejandro Llanos Cuentas, Yocelinda Meza, Gilda Troncos, Frédéric M. Poly, Adrian C. Paskey, Matthew R. Lueder, Gregory K. Rice, Regina Z. Cer, Kimberly A. Bishop-Lilly, María Silva, Max Grogl

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APOE modulates ferroptosis to drive macrophage polarization toward the M2 type and enhance PTC migration and invasion by Ziwen Li, Min Li, Sinuo Sun, Yu Bin, Suwei Zuo, Ronghua Huo, Jiayin Song, Gang Xue, Xu Lin, Jingfang Wu

“…However, whether APOE promotes PTC progression through ferroptosis modulation remains unclear. …”
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Expression pattern and clinical significance of MerTK on circulating NK cells in systemic lupus erythematosus by Jianping Guo, Yin Su, Xiao Han, Yin Zhu, Haojie Xu, Ranran Yao, Ziye Wang, Ruyu Liang, Wenwen Pei, Renge Liang

“…Our findings indicate that circulating NK-cell specific expression of MerTK may play a role in the development and progression of SLE.…”
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Probable chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids syndrome: management with corticosteroids and intravenous immunoglobulin—a ca... by J. A. Encarnación, A. León Hernández, G. Litrán López, J. L. Alonso-Romero, M. I. De la Fuente Muñoz, E. Cárdenas Cánovas, P. Ruiz Carreño, M. Royo-Villanova, C. Manso

“…The patient attended the emergency department at his referral hospital following a 1-month history of progressive neurological symptoms, including diplopia, blurred vision, facial paresis, and gait disturbance attributed to lower limb weakness. …”
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Blocking NKG2A in Echinococcus multilocularis infection partially relieves impairment of NK cell function of the host by Ayinuer Aierken, Aili Aierken, Kalibixiati Aimulajiang, Abuduaini Abulizi, Zhongdian Yuan, Chang Liu, Dalong Zhu, Hanyue Zhao, Tuerganaili Aji

“…Deletion of NK cells in an E. multilocularis-infected mice model clearly resulted in more aggressive disease progression. Conversely, blocking NKG2A on NK cells results in increased secretion of TNF-α, and Granzyme B by NK cells. …”
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Thoracic Aortic Aneurysm Growth Rates and Predicting Factors: A Systematic Review and Meta‐Analysis by Matthew Henry, Carlos A. Campello Jorge, Pieter A.J. van Bakel, Heather A. Knauer, Mark MacEachern, Joost A. van Herwaarden, Gisela Teixidó‐Tura, Arturo Evangelista, Richmond W. Jeremy, C. A. Figueroa, Himanshu J. Patel, Marion Hofmann Bowman, Kim Eagle, Nicholas S. Burris

“…Background Thoracic aortic aneurysm (TAA) is an indolent, potentially fatal disease, which progresses at variable rates that are influenced by pathogenesis and patient characteristics. …”
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Molecular mechanisms of the Xiao-chai-hu-tang on chronic stress-induced colorectal cancer growth based on an integrated network pharmacology and RNA sequencing approach with experi... by Wang Yao, Dong-Ming Hua, Ying-Ru Zhang, Yi-Yang Zhao, Ying Feng, Zhao-Zhou Zhang, Zhong-Ya Ni, Hai-dong Guo, Yun-Feng Guan, Yan Wang

“…ELISA, RT-qPCR and immunofluorescence were performed to detect the expression of inflammation related genes. …”
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Study on the potential clinical significance of subclinical stent edge effects after drug-eluting stent implantation by Yi Xu, Yi-Fei Wang, Meng-Yao Zhao, Wei You, Tian Xu, Pei-Na Meng, Xiang-Qi Wu, Zhi-Ming Wu, Xiao-Han Kong, De-Lu Yin, Mei-En Zhan, Hai-Bo Jia, Bin Liu, Fei Ye

“…A total of 252 patients were enrolled from one of our previous randomized controlled studies, who were detected by optical coherence tomography (OCT) immediately after DES implantation and 1 year later. …”
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The Role of the Bone Marrow Microenvironment in Physical Function and Quality of Life in Patients with Multiple Myeloma After First-Line Treatment with Novel Agents and Autologous... by Polyxeni Spiliopoulou, Pantelis Rousakis, Chrysanthi Panteli, Evangelos Eleutherakis-Papaiakovou, Magdalini Migkou, Nikolaos Kanellias, Ioannis Ntanasis-Stathopoulos, Panagiotis Malandrakis, Foteini Theodorakakou, Despina Fotiou, Evangelos Terpos, Vassilios Myrianthopoulos, Maria Gavriatopoulou, Ourania E. Tsitsilonis, Efstathios Kastritis, Meletios Athanasios Dimopoulos, Gerasimos Terzis

“…Background/Objectives: Multiple myeloma is a malignancy of plasma cells detected in the bone marrow, inducing symptoms like anemia, hypercalcemia, renal problems, and bone fractures in multiple myeloma patients, affecting their quality of life. …”
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