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11921
The Application of Traditional Chinese Medicine-Derived Formulations in Cancer Immunotherapy: A Review
Published 2025-01-01“…They enhance the immune system’s ability to detect and destroy cancer cells, promote apoptosis in tumor cells, inhibit tumor growth and metastasis, and augment the effectiveness of conventional cancer treatments. …”
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11922
Mendelian randomization study of lipid species reveals causal relationship with syphilis
Published 2025-04-01“…Abstract Although some studies have reported a possible association between lipid and the development and progression of syphilis, the overall causal relationship between lipid and syphilis remains unclear. …”
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11923
Serum and urine apolipoprotien A1 (ApoA1) as biomarkers in bladder cancer
Published 2024-06-01“…Multiple inquiries have demonstrated that APOA1 plays a pivotal role in the progression, infiltration, and spread of tumors. Objectives. …”
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11924
Enhancer remodeling characteristics in diffuse-type gastric cancer and role in upregulating GDF15 expression and promoting cancer cachexia
Published 2025-06-01“…Conclusion DGC exhibits enhancer remodeling, which regulates the expression of the cachexia-associated gene GDF15, and thereby contributes to the pathogenesis and progression of cancer cachexia. …”
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11925
Safety assessment of laronidase: real-world adverse event analysis based on the FDA adverse event reporting system (FAERS)
Published 2025-08-01“…The results revealed that common AEs of laronidase such as pyrexia [n = 465, ROR = 6.23 (5.68–6.83)], pneumonia [n = 223, ROR = 3.22 (2.82–3.68)], cough [n = 167, ROR = 2.78 (2.38–3.23)], influenza [n = 114, ROR = 4.95 (4.12–5.95)], urticaria [n = 106, ROR = 2.99 (2.47–3.62)], disease progression [n = 101, ROR = 3.95 (3.25–4.81)]. Furthermore, we detected probable unexpected AEs like seizures [n = 75, ROR = 3.1 (2.47–3.89)], hydrocephalus [n = 60, ROR = 50.47 (39.1–65.14)], blindness [n = 44, ROR = 5.02 (3.73–6.75)], glaucoma [n = 32, ROR = 7.56 (5.34–10.69)]. …”
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11926
Analysing Open-source Images to Assess Face Mask Usage for Epidemiological Studies
Published 2025-03-01“…AI-powered image analysis systems can help identify high-risk areas, track disease progression, and inform targeted interventions, ultimately contributing to more effective public health strategies and improved population health outcomes.…”
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11927
MicroRNA-668 alleviates renal fibrosis through PPARα/PGC-1α pathway
Published 2024-12-01“…Abstract Background The involvement of microRNA-668 (miR-668) in the onset and progression of renal fibrosis remains unclear. To this end, we aimed to explore the relevant mechanism of miR-668 in renal fibrosis. …”
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11928
Dynamic conduction and repolarisation changes in early arrhythmogenic right ventricular cardiomyopathy versus benign outflow tract ectopy demonstrated by high density mapping &...
Published 2014-01-01“…<h4>Conclusions</h4>Significant changes in dynamic conduction and repolarization are apparent in early ARVC before detectable RV structural abnormalities, and were present to a lesser degree in probable ARVC patients. …”
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11929
Effect of combined Kaempferia parviflora extract and fenitrothion treatment on male reproductive parameters in a murine model
Published 2025-04-01“…Results: Eight phytochemical compounds were detected in the ethanolic extract of K. parviflora via GC-MS. …”
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11930
Serum CDC42 level change during abiraterone plus prednisone treatment and its association with prognosis in metastatic castration-resistant prostate cancer patients
Published 2025-03-01“…Additionally, serum CDC42 was detected in thirty age-matched healthy controls (HCs). …”
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11931
Expression of arginase 1 and tyrosine kinase Mer by blood monocytes in the dynamics of physiological pregnancy
Published 2023-06-01“…There is a direct correlation between the number of Arg1+ and MerTK+ cells in intermediate Mo, which increases with the progression of pregnancy, and in the 3rd trimester is also detected in classical and non-classical Mo. …”
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11932
Risk factors for irreversible organ damages in peri- and postmenopausal women with systemic lupus erythematosus
Published 2018-12-01“…Musculoskeletal system injuries ranked first among other disorders: osteoporosis (OP) and muscle weakness were detected in 76 (38.6%) and 69 (35.0%) patients, respectively. …”
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11933
Bone cell differentiation and mineralization in wild-type and osteogenesis imperfecta zebrafish are compromised by per- and poly-fluoroalkyl substances (PFAS)
Published 2025-01-01“…Addressing this question represents a need for ensuring global health and wellbeing to all individuals in a world facing the progressive increase of aging and aging related diseases. …”
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11934
Characterization of silver nanoparticles (AgNPs) synthesized using polyphenolic compounds from Phyllanthus emblica L. and their impact on cytotoxicity in human cell lines
Published 2024-12-01“…Research has also evaluated the potential of nanoparticles to inhibit cancer progression, revealing promising prospects for enhancing anticancer therapies. …”
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11935
Association between body folate status and muscle mass: a cross-sectional study of the National Health and Nutrition Examination Survey 2011–2018
Published 2025-07-01“…Abstract Background Sarcopenia is a progressive muscle disease associated with loss of muscle mass, strength and function. …”
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11936
Patient-centric analysis of Orientia tsutsugamushi spatial diversity patterns across Hainan Island, China.
Published 2025-03-01“…Additionally, this study provides valuable insights into the transmission dynamics and infection progression of scrub typhus, using gene flow analysis and multilocus sequence typing to identify major sub-genotypes.…”
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11937
First-phase insulin response (FPIR) to intravenous glucose tolerance test (IVGTT), insulin sensitivity and long-term follow-up in ?- transfusion-dependent thalassemia (TDT) normog...
Published 2021-02-01“…Conclusions: These data demonstrated, for the first time, a progressive deterioration in glucose homeostasis in ?…”
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11938
The burden of attention deficit hyperactivity disorder and incidence rate forecast in China from 1990 to 2021
Published 2025-03-01“…ObjectiveTo analyze the temporal trends and future projections of attention-deficit/hyperactivity disorder (ADHD) burden among children and adolescents in China from 1990 to 2021, and to identify age-, period-, and cohort-specific drivers of disease progression.MethodsUsing data from the Global Burden of Disease Study 2021, we conducted joinpoint regression to detect trend transitions in ADHD incidence and age-standardized rates. …”
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11939
miR-21 and miR-155 in the regulation of TGF-β1/SMAD signaling pathway of the line breast cancer cells with different metastatic potential
Published 2015-09-01“…High expression of miR-21 was detected in all the tumor cell lines (MCF-7, ZR-75-1 and BT-474). …”
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11940
The effect of lactate dehydrogenase B and its mediated histone lactylation on chondrocyte ferroptosis during osteoarthritis
Published 2025-05-01“…Western blotting assay served for detecting the relative expression of proteins and protein lactylation. …”
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