High rate and large intercentre variability in retreatment of retinopathy of prematurity in infants born by Ann Hellström, Lotta Gränse, Marie Saric, Birgitta Sunnqvist, Agneta Wallin, Kristina Tornqvist, Eva Larsson, Eva Morsing, Gerd E Holmström, Pia Lundgren, Anna-Lena Hård, Lena Jacobson, Abbas Al-Hawasi, Lois LE Smith

“…Retreatment rate was not associated with GA, BW or sex but with APROP, treatment method (anti-VEGF) and treatment centre where the laser was performed (p<0.001). Twenty eyes progressed to retinal detachment, and two infants developed unilateral endophthalmitis after anti-VEGF treatment.Conclusion Infants, born at <24 weeks’ GA, had high rates of treatment-warranting ROP and retreatments. …”
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Profound Neuropathy after Penetrating Transection of the Sciatic Nerve by Femoral Cerclage Wire: Illustrative Case and Management Strategy by John K. Yue, Jun Yeop Oh, Alexander A. Aabedi, Jia-Shu Chen, Kenneth X. Probst, Vinil N. Shah, Rosanna L. Wustrack, Line G. Jacques

“…Sciatic nerve injury associated with total hip arthroplasty (THA) confers chronic and progressive disability. Mechanisms of injury are heterogeneous and management nuances are often case-specific. …”
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mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance by Philip Stavrides, Chris N Goulbourne, James Peddy, Chunfeng Huo, Mala Rao, Vinod Khetarpal, Deanna M Marchionini, Ralph A Nixon, Dun-Sheng Yang

“…In the Q175 and/or TRGL/Q175 mice, mHTT was detected in autophagic vacuoles and also exhibited a high level of colocalization with autophagy receptors p62/SQSTM1 and ubiquitin in the IBs. …”
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Exploration of demographic prevalence of mild cognitive impairment using Montreal cognitive assessment: A cross-sectional pilot study in the Cape Coast Metropolis, Ghana. by David Larbi Simpong, George Nkrumah Osei, Richeal Odarko Mills, Christopher Amaleyele Anyebem, Benjamin Kofi Aikins, Charlotte Gyanwaa Melfah, Bridget Amoanimaa Osei, Ansumana Bockarie

“…Conclusion: The MoCA tool is a useful for detecting MCI, particularly among Ghanaians with at least 7 years of formal education. …”
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Exploring correlations between gut mycobiome and lymphocytes in melanoma patients undergoing anti-PD-1 therapy by Natalia Szóstak, Michał Budnik, Katarzyna Tomela, Luiza Handschuh, Anna Samelak-Czajka, Bernadeta Pietrzak, Marcin Schmidt, Mariusz Kaczmarek, Łukasz Galus, Jacek Mackiewicz, Andrzej Mackiewicz, Piotr Kozlowski, Anna Philips

“…This result extends our former research, where M. restricta and C. albicans were associated with an increased risk of melanoma progression and a poorer response to anti-PD-1 treatment.…”
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Epithelial tumors of the thymus with pleural dissemination: the potential role of surgery by O. V. Pikin, A. B. Ryabov, O. A. Aleksandrov, K. I. Kolbanov, V. A. Glushko, V. V. Barmin, V. A. Bagrov, D. E. Martynova

“…Pleural metastases of thymic epithelial tumors are detected in 5–7 % of patients at initial diagnosis and in 10 % of patients during a follow-up after radical surgery for the primary tumor. …”
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Disrupted synaptic gene expression in Fabry disease: Findings from RNA sequencing by Laura López-Valverde, María E. Vázquez-Mosquera, Cristóbal Colón-Mejeras, J. Víctor Álvarez, Beatriz Martín López-Pardo, Lluis Lis López, Rosario Sánchez-Martínez, Manuel López-Mendoza, Mónica López-Rodríguez, Eduardo Villacorta-Argüelles, María A. Goicoechea-Diezhandino, Francisco J. Guerrero-Márquez, Saida Ortolano, Elisa Leao-Teles, Álvaro Hermida-Ameijeiras, María L. Couce

“…This defect leads to the progressive accumulation of glycosphingolipids, resulting in kidney, heart, and nervous system damage, which contributes to significant morbidity and mortality. …”
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Screening of active components in Astragalus mongholicus Bunge and Panax notoginseng formula for anti-fibrosis in CKD: nobiletin inhibits Lgals1/PI3K/AKT signaling to improve renal... by Fang Yang, Tong Li, Xiao-qian Zhang, Yi Gong, Hongwei Su, Junming Fan, Li Wang, Qiong-dan Hu, Rui-zhi Tan

“…The Astragalus mongholicus Bunge and Panax notoginseng formula (A&P) has been clinically shown to effectively slow down the progression of chronic kidney disease (CKD) and has demonstrated significant anti-fibrosis effects in experimental CKD model. …”
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Temporal TCR dynamics and epitope diversity mark recovery in severe COVID-19 patients by Kriti Khare, Kriti Khare, Sunita Yadav, Sayanti Halder, Yogiraj Ray, Yogiraj Ray, Dipyaman Ganguly, Dipyaman Ganguly, Rajesh Pandey, Rajesh Pandey

“…IntroductionSevere COVID-19 is characterized by immune dysregulation, with T cells playing a central role in disease progression and recovery. However, the longitudinal dynamics of the T cell receptor (TCR) repertoire during the course of severe illness remain unclear.MethodsTo investigate temporal changes in adaptive immunity, we analyzed peripheral blood samples from the ICU-admitted severe COVID-19 patients (n = 36) collected at three time points: Day 1 (T1), Day 4 (T2), and Day 7 (T3). …”
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Establishment and validation of the prognostic risk model based on the anoikis-related genes in esophageal squamous cell carcinoma by Shasha Cao, Ming Li, Zhiying Cui, Yutong Li, Wei Niu, Weiwei Zhu, Junkuo Li, Lijuan Duan, Shumin Lun, Zhaowei Gao, Yaowen Zhang

“…Anoikis-related genes (ARGs) are crucial to cancer progression. Therefore, more studies on the relationship between ARGs and ESCC are warranted.Methods The study acquired ESCC-related transcriptome data from TCGA. …”
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Applications of MR Finger printing derived T1 and T2 values in Adult brain: A Systematic review [version 1; peer review: 2 approved] by Rajagopal Kadavigere, Obhuli Chandran M, Kaushik Nayak, Abhijith S, Saikiran Pendem, Varsha Raghu, Shailesh Nayak S, Riyan Mohamed Sajer, Tancia Pires, Priyanka -

“…With reduced acquisition times, MRF outperforms conventional MRI in detecting subtle pathologies, distinguishing properties, and providing reliable biomarkers.…”
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Nkx2‐5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E–Deficient Mice by Meng Du, Xiaojing Wang, Xin Tan, Xiangrao Li, Dandan Huang, Kun Huang, Liu Yang, Fengxiao Zhang, Yan Wang, Dan Huang, Kai Huang

“…Molecular studies indicated that expression of specific members of matrix metalloproteinases and tissue inhibitor of metalloproteinases, which play a crucial role in the progression of atherosclerosis, were directly regulated by Nkx2‐5. …”
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Platelets Image Classification Through Data Augmentation: A Comparative Study of Traditional Imaging Augmentation and GAN-Based Synthetic Data Generation Techniques Using CNNs by Itunuoluwa Abidoye, Frances Ikeji, Charlie A. Coupland, Simon D. J. Calaminus, Nick Sander, Eva Sousa

“…Platelets play a crucial role in diagnosing and detecting various diseases, influencing the progression of conditions and guiding treatment options. …”
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Identification and treatment of Enterococcus avium-induced diabetic foot ulcer: a case report and microbiome analysis by Yuanling Jin, Tao Zhu, Xiao Cai, Zheng Fu, QiangLong Pan, HaiXia Tu, ShouXing Wang, Yan Li

“…However, we observed recurrent bacterial infections, based on the clinical progression. Second-generation sequencing detected various pathogens. …”
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Exploring intraoperative hemorrhage and early recurrence in pelvic malignant solitary fibrotic tumors: a case report and literature review by Dong-Mei Li, Dong-Mei Li, Dan Tang, Dan Tang, Ming-Rong Qie, Ming-Rong Qie, Min-Min Hou, Min-Min Hou

“…Early postoperative surveillance MRI at one month detected local recurrence with regional lymph node metastases. …”
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Relevance of TNF-α, IL-6 and IRAK1 gene expression for assessing disease severity and therapy effects in tuberculosis patients by Ivana Buha, Vesna Škodrić-Trifunović, Tatjana Adžić-Vukičević, Aleksandra Ilić, Ana Blanka-Protić, Mihailo Stjepanovic, Marina Anđelković, Miša Vreća, Jelena Milin-Lazović, Vesna Spasovski, Sonja Pavlović

“…A better understanding of the functions of the cytokine network involved in the state and progression of TBC could identify specific molecular markers for monitoring of disease activity as well as therapy outcomes in TBC patients. …”
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Changes of primary headache related white matter lesions in pediatric patients by Erhan Bayram, Uluç Yiş, Cem Paketçi, Derya Okur, İpek Polat, Handan Çakmakcı, Semra Hız, Banu Anlar

“… We aimed to describe the long-term prognosis of white matter lesions detected on magnetic resonance imaging in children with primary headache. …”
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Exposure to polyethylene and polyvinylchloride microplastics caused advanced puberty onset in females through promoting hypothalamic GnRH expression by Shaolian Zang, Fei Wang, Yang Ouyang, Weiwei Cheng, Pin Li, Xiaoqin Yin

“…This study provided valuable evidence that MPs threatened the normal progression of female pubertal development.…”
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A novel homozygous W99G mutation in CLDN-16 gene causing familial hypomagnesemic hypercalciuric nephrocalcinosis in Turkish siblings by Caner Alparslan, Elif Perihan Öncel, Sinem Akbay, Demet Alaygut, Fatma Mutlubaş, Mansur Tatlı, Martin Konrad, Önder Yavaşcan, Belde Kasap-Demir

“…Bilateral medullary nephrocalcinosis was detected on abdominal ultrasound. His ophthalmologic examination was unremarkable. …”
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Effects of Bufexamac, a class IIb HDAC inhibitor, on behavior and neuropathological features in an Aβ-induced rat model of Alzheimer's disease by Monireh Mirehei, Fereshteh Motamedi, Nader Maghsoudi, Zahra Mansouri, Soudabeh Naderi, Fariba Khodagholi, Fatemeh Abbaszadeh

“…It has been suggested that Alzheimer's disease (AD), a progressive neurological condition, can potentially be treated through epigenetic means by targeting histone deacetylases (HDACs), enzymes that regulate gene expression. …”
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