USP37-stabilized SALL4 promotes the keloid formation by PI3K/AKT pathway by Shuo Fang, Zishuo Wang, Jianguo Xu, Miao Xu, Jiesong Zhou, Yuntong Zhang, Chunyu Xue

“…Abstract Spalt-like transcription factor 4 (SALL4) plays a vital role in the progression of many human diseases. However, the role and mechanism of SALL4 regulates in keloid formation remain unclear. …”
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B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection. by Clinton O Ogega, Nicole E Skinner, Andrew I Flyak, Kaitlyn E Clark, Nathan L Board, Pamela J Bjorkman, James E Crowe, Andrea L Cox, Stuart C Ray, Justin R Bailey

“…Antibodies targeting the hepatitis C virus (HCV) envelope glycoprotein E2 are associated with delayed disease progression, and these antibodies can also facilitate spontaneous clearance of infection in some individuals. …”
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Bidirectional relationship between platelet count and skin cancer: tumor drug resistance mechanisms by Chao Guo, Jiaqin Deng, Tianhua Wen, Jinzhou Li, Peilin Zeng, Chao Liang

“…Abstract Background Platelets (PLT) play a crucial role in tumor progression, including tumor growth, metastasis, and immune evasion. …”
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Association of Hepatitis B Virus Polymerase/Surface Gene Overlap Mutations Developed in Nucleos(t)id Analogue Treatments of Chronic Hepatitis B with Hepatocellular Carcinoma by Yeşim Saliha Gürbüz, Seda Erem Basmaz, Murat Sayan, Sadettin Hülagü

“…The rtA181T/sW172* mutation should be screened in patients receiving treatment, and when detected, they should be closely monitored for HCC development.…”
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Early Diagnosis of Alzheimer’s Disease in Human Participants Using EEGConformer and Attention-Based LSTM During the Short Question Task by Seul-Kee Kim, Jung Bin Kim, Hayom Kim, Laehyun Kim, Sang Hee Kim

“…<b>Background/Objectives</b>: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder advancing through subjective cognitive decline (SCD), mild cognitive impairment (MCI), and dementia, making early diagnosis crucial. …”
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Multimodal imaging of tumour-related lipid exudation and exudative retinal detachment following brachytherapy in choroidal melanoma by Elena Ros-Sanchez, David Oliver-Gutierrez, Paul Buck, Tetiana Goncharova-Simón, Marta Garrido-Marín, Miguel Ángel Zapata-Victori, Anna Boixadera

“…One-month post-treatment, the patient developed progressive exudative retinal detachment with lipid exudation, despite preserved visual acuity. …”
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Identification of cell specific biomarkers for intellectual disability via single cell RNA sequencing and transcriptomic bioinformatics approaches by Kh Mujahidul Islam, Md Habibur Rahman, Md. Arju Hossain, Mahfuj Khan, Md. Mizanur Rahman, Prosenjit Saha Apu, Md Imran Hasan, Siddique Akber Ansari, Mahammad Humayoo

“…This study used scRNA-seq and transcriptomics data analysis to define unique biomarkers associated with T cell types throughout the progression of ID. Ongoing research on the activity of ID genes is contributing to a greater understanding of the pathophysiology of ID and will become more scientific and research-based in future.…”
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Multimodal evoked potentials and transcranial magnetic stimulation in diagnostics of children with encephalitis, acute disseminated encephalomyelitis and multiple sclerosis by E. Yu. Skripchenko, A. V. Klimkin, V. B. Voitenkov, N. V. Skripchenko, A. V. Surovtseva

“…The P100 latency &gt;132 msec and lack of cortical evoked motor response from the m. abductor hallucis at MS onset indicate a high risk of disease progression and further development of disabilityConclusion. …”
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Advancing Precision Medicine: The Role of Genetic Testing and Sequencing Technologies in Identifying Biological Markers for Rare Cancers by Joviana Farhat, Lara Alzyoud, Mohammad AlWahsh, Animesh Acharjee, Basem Al‐Omari

“…Consequently, they help detect main intrinsic markers that are crucial for personalizing diagnosis, treatment options, and prognostic assessments, leading to better patient prognosis. …”
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Respiratory Syncytial Virus Induces B Cell Activating Factor (BAFF) in Airway Epithelium: A Potential Avenue for Mucosal Vaccine Development by Wael Alturaiki, Brian Flanagan

“…The treatments resulted in a progressive increase in gene expression over time, accompanied by higher protein levels. …”
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Effect and mechanism of PYCR1 on biological function of hepatocellular carcinoma cells under hypoxia by Jiayi Guo, Xinxin Jin, Junli Zhang, Yuming Zhang, Wenjuan Wu

“…The energy metabolism kit and Western blot were used to detect the metabolic changes of SUN449 and Hep3B liver cancer cells under hypoxic conditions. …”
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High Thymic Output of Effector CD4+ Cells May Lead to a Treg : T Effector Imbalance in the Periphery in NOD Mice by Yuan Zhao, Pascale Alard, Michele M. Kosiewicz

“…In our animal facility, the incidence of T1D in NOD mice is high at 90-100% and the percentages of peripheral CD4+Foxp3+ cells in ~9-10-week-old female NOD mice are decreased compared to control (B6) mice shortly before high glucose is first detected (~12 weeks). These data suggest that there is an imbalance between Tregs and potentially pathogenic effector T cells at this age that could have significant impact on disease progression to overt diabetes. …”
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Binding patterns of glycine receptor autoantibodies are related to clinical syndromes by Inken Piro, Anna-Lena Wiessler, Eleni Kakavela, Betül Baykan, Erdem Tüzün, Carmen Villmann, Claudia Sommer

“…Similarly, autoantibody deposits were detected in GlyR expressing higher brain areas for each patient. …”
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Comparative Effects of Intermittent vs. Constant Ceftiofur Hydrochloride Exposure on <i>Staphylococcus aureus</i> In Vitro by Junli Wang, Chongyang Li, Fanxi Guo, Zugong Yu

“…No significant MIC increase was found in other groups, but a progression from susceptibility to persistence and then to tolerance was observed in the 100 × MIC intermittent group. …”
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Temporary hypocalcemia induced by cetuximab sarotalocan without hypomagnesemia in a patient with hypoparathyroidism: a novel case report by Moeko Kado, Yoshitaka Saito, Tatsuhiko Sakamoto, Takayoshi Suzuki, Yoh Takekuma, Mitsuru Sugawara

“…Herein, we report a case of independent hypocalcemia without hypomagnesemia during treatment and discuss symptom progression. Case Presentation A female patient with left epipharyngeal cancer, hypothyroidism, and hypoparathyroidism was treated with cetuximab and sarotalocan. …”
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From sexualized torture and gender-based torture to genderized torture: The urgent need for a conceptual evolution by Pau Pérez-Sales, Maggie Zraly

“…Arriving at a general framework for the reconceptualization of torture, and progressively widening the analytical scope of gender and torture, are priorities. …”
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INTENSITY TRANSFORMATION FOR THE MIXTURE COMPOSITIONS OF THE SOLID LUBRICATING BY LACTIN OF LARGE GRAIN LABA AT 1% EFFECT OF METHACRYLIC ACID by G.A. Yeroshenko, Yu. V. Timoshenko

“… An increase in the average life expectancy of a person, the occurrence of pathology of solid teeth tissues, periodontal tissues, leads to progressive loss of teeth. In connection with this, there is a need for dentures. …”
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Features of biology and prospects of modern fishery for pacific herring <i>Clupea pallasii</i> on the shelf of southern Kuril Islands by A. O. Zolotov, A. V. Buslov, S. S. Ponomarev

“…The stock recovery on the shelf of southern Kuril Islands is detected that corresponds to recovery of the whole Sakhalin-Hokkaido population of this species. …”
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EPHA5 enhances stemness and decreases gefitinib sensitivity via Wnt signaling pathway in non-small lung cancer by Jie Li, Yehan Zhu

“…Erythropoietin-producing hepatocellular receptor A5 (EPHA5), a member of the Eph tyrosine kinase receptor family, has been implicated in various stages of tumor progression. However, the specific role of EPHA5 in NSCLC remains poorly understood. …”
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Intravitreal Administration Effect of Adipose-Derived Mesenchymal Stromal Cells Combined with Anti-VEGF Nanocarriers, in a Pharmaceutically Induced Animal Model of Retinal Vein Occ... by Eleni Gounari, Anastasia Komnenou, Evangelia Kofidou, Stavroula Nanaki, Dimitrios Bikiaris, Stavroula Almpanidou, Kokkona Kouzi, Vasileios Karampatakis, George Koliakos

“…Conclusively, a stem cell-based therapy for RVO is proposed, accompanied by sustained release of anti-VEGF, in order to combine the paracrine action of ASCs and the progressive reduction of neovascularization.…”
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