The prognostic role of perinephric adipose tissue macrophages in localized clear cell renal cell carcinoma by Lu Fang, Heqin Zhan, Chao Yang, Tao Zhang, Yi Wang, Guangyuan Li

“…Abstract Background Tumor-associated macrophages (TAMs) are linked with tumor progression in clear cell renal cell carcinoma (ccRCC), but the role of perinephric adipose tissue macrophages (PATMs) in ccRCC has not been elucidated. …”
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Evaluation of the bone tissue metabolism in patients with generalized periodontitis of various degrees exposed to work-related harmful factors by the oral fluid Klotho protein cont... by I. V. Vozna, A. V. Samoilenko, S. V. Pavlov, O. O. Kokar

“…The indicator of Klotho protein is an early marker of the periodontal disease progression and varies inversely with the severity of periodontitis, starting in the early stages of the disease. …”
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Clinical evaluation of chitosan/polycaprolactone nanofibrous scaffolds releasing tetracycline hydrochloride in periodontal pockets of patients with chronic periodontitis by Janet Moradi Haghgoo, Parviz Torkzaban, Parisa Hashemi, Rana Sarvari, Sana Hashemi, Elahe Fakhri, Behnaz Alafchi

“…The role of bacteria in the initiation and progression of periodontitis has led to a great interest in using antibiotics to suppress pathogenic microbiota. …”
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INDICATORS OF CYTOKINE ACTIVITY AND BETA-ENDORPHIN PRODUCTION LEVEL IN ARTERIAL HYPERTENSION ASSOCIATED WITH ASTHENIC/NEUROTIC DISORDERS IN YOUNG MEN EMPLOYED IN STRESSFUL PROFESSI... by A. V. Gertsev, V. N. Ischuk, Yu. N. Zakrevsky

“…At the present time, arterial hypertension is the most common somatic pathology among young and able-bodied persons. Development and progression of hypertension in young people occupied with stressful jobs presents a particular problem. …”
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Glutamate Metabolism in Brain Structures in Experimental Hemorrhagic Shock by V. N. Jakovlev, P. N. Savilov, Y. V. Bulgakova

“…The accumulation of ammonia regardless of the HS stage was detected only inthe sensorimotor cortex, limbic system and diencephalon; in the medulla oblongata ammonium increase was found only during the agony.Сonclusion. …”
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Associations of adipocytokine expression and cardiovascular risk factors in stable coronary artery disease by E. V. Belik, O. V. Gruzdeva, Yu. A. Dyleva, D. A. Borodkina, M. Yu. Sinitsky, E. E. Bychkova, E. I. Palicheva

“…The presence of such risk factors as male sex, age of 50-59 years, dyslipidemia and hypertension in patients can enhance atherogenesis and contribute to the further progression of CAD.…”
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Physical modeling experiments to study periodic activation of faults in seismic zones by S. A. Bornyakov, I. A. Panteleev, A. V. Cheremnykh, A. A. Karimova

“…The digital image correlation method (DIC) detected the moments of impulse activation and displacements along the entire fault or its major segment. …”
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The characteristics of methicillin-resistant Staphylococcus aureus co-infection in COVID-19 pneumonia by Feifei Gu, Yuyi Zhang, Jingyong Sun, Wei Guo, Lizhong Han

“…Patients with MRSA-COC were significantly older (P=0.0492), had higher rates of severe pneumonia progression (P=0.0006), and carried greater comorbidity burdens. …”
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Integration of pharmacodynamics, network pharmacology and metabolomics to elucidate the effect and mechanism of Jingfang Granule in the treatment of Paraquat induced Pulmonary fibr... by Rujing Yue, Tianye Yang, Dejun Niu, Zhen Zeng, Xishuang Wang, Lihong Pan, Jingchun Yao

“…Then, the expression of fibrosis-associated protein α-SMA and TGFβ1/Smad2,3 signaling pathway was detected by immunohistochemistry and western blot. …”
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Dynamic responses and stability analysis of a large-scale slope deposit under non-uniform seismic input by Chong Shi, Tianjiao Qiao, Dawei Xue, Su Wu, Cong Zhang

“…The increase in epicentral distance and earthquake intensity leads to an increase, with a decreasing rate, in overall safety factors. As time progresses, all computed safety factors show diminished fluctuation and approach specific values. …”
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Textural and Structural Modification of Homo-Ionic Montmorillonite by Mervat S. Hassan

“…On the other hand, thermal treatment after leaching led to a considerable increase in the specific surface areas, pore volumes and microporosities for those samples subjected to heating for a short time, but decreased progressively with increasing heating time, with no difference being observed to the exchangeable cations. …”
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Single-cell sequencing and transcriptomic data reveal that P65 activation significantly promotes microglia-mediated neuroinflammation after ischemic stroke by Ruiyu Wang, Yilun Qian, Xinchen Zhou, Hang Xu, Yu Wang, Yao Geng, Tianshu Wang, Binxiu Sha

“…Notably, inhibition of P65 phosphorylation effectively suppressed the progression of inflammation during cerebral I/R injury. …”
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MiR-23a-5p affects postmenopausal osteoporosis by targeting ALX3 to regulate osteoblast differentiation by Honghao Zhang, Wenjun Rao, Rubing Lin, Yingxuan Huang

“…Conclusions miR-23a-5p exhibits significantly elevated expression levels in PMOP and it might serve as a promising biomarker. miR-23a-5p plays a pivotal role in the progression of PMOP by negatively regulating ALX3 expression, thereby influencing the osteogenic differentiation process of MC3T3-E1 cells.…”
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Organ-specific LPS-induced inflammatory gene expression in adult Zebrafish by Yi. Ma, A. V. Fedorov, K. A. Kondratov, A. A. Knyazeva, M. L. Vasyutina, A. S. Golovkin

“…Systemic inflammation is known to be a key component of infection and non-infection diseases progression and may lead to multiorgan failure, persistent inflammation, immunosuppression, catabolism syndrome or even indolent death. …”
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RETRACTED ARTICLE: Circular RNA ATXN7 promotes the development of gastric cancer through sponging miR-4319 and regulating ENTPD4 by Zhen Zhang, Honglei Wu, Zhaosheng Chen, Guangchun Li, Bin Liu

“…Methods qRT-PCR analysis was performed to detect the expression of circATXN7, miR-4319 and ENTPD4 in GC tissues and cells. …”
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Sex-Specific Impact of 17β-Estradiol and Testosterone Levels on Inflammation and Injury in Acute Myocardial Infarction—Preliminary Results by Niya E. Semerdzhieva, Adelina D. Tsakova, Vesela V. Lozanova

“…However, endogenous 17β-estradiol (E2) can accelerate atherosclerosis progression. Aim: The purpose of this study was to test for the significance of the sex-specific associations of gonadal hormones with the extent of the inflammatory response, myocardial damage, and ventricular arrhythmia risk in acute myocardial infarction (MI). …”
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Prognostic, oncogenic roles, and pharmacogenomic features of AMD1 in hepatocellular carcinoma by Youliang Zhou, Yi Zhou, Jiabin Hu, Yao Xiao, Yan Zhou, Liping Yu

“…Conclusion The present study indicates that AMD1 functions as a potential role in HCC progression and may serve as a therapeutic target in HCC. …”
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Urinary Exosomal MicroRNA Profiling in Incipient Type 2 Diabetic Kidney Disease by Yijun Xie, Yijie Jia, Xie Cuihua, Fang Hu, Meng Xue, Yaoming Xue

“…Owing to their high stability, urinary exosomal miRNAs can be useful predictors of the progression of early-stage DKD to renal failure; fluid biopsies are ideal for detecting abnormalities in these miRNAs. …”
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More but Smaller: Marine Heatwaves Exacerbate Size Truncation in Overfished Fish Communities in the Skagerrak by Kjell Magnus Norderhaug, Portia Joy Nillos Kleiven, Thomas Wernberg, Ann‐Elin Synnes, Karen Filbee‐Dexter, Sigurd Espeland, Jonas Thormar, Kyrre Heldal Kartveit, Lene Christensen, Even Moland

“…ABSTRACT As we are progressing through the Anthropocene, it is imperative to understand how ecosystems degraded by historical impacts respond to future pressures. …”
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Non-redundant roles of the CCR1 and CCR2 chemokine axes in monocyte recruitment during lung metastasis by Alessia G. Liner, Merel van Gogh, Marko Roblek, Matthias Heikenwalder, Lubor Borsig

“…Monocytes and monocyte-derived macrophages facilitate cancer progression and metastasis. Inflammatory monocytes expressing CCR2 are actively recruited to metastatic lungs, where they promote tumor cell extravasation, metastatic outgrowth, and an immunosuppressive environment. …”
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