Zonated Copper‐Driven Breast Cancer Progression Countered by a Copper‐Depleting Nanoagent for Immune and Metabolic Reprogramming by Lin Chen, Saibo Ma, Hao Wu, Lingna Zheng, Yunpeng Yi, Guangnian Liu, Baoyi Li, Jiayi Sun, Yang Du, Bing Wang, Yike Liu, Cheng Zhang, Jing Chang, Yuheng Pang, Wenjing Wang, Meng Wang, Motao Zhu

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METTL3-dependent DLG2 inhibits the malignant progression of cervical cancer by inactivating the Hippo/YAP signaling by Mei Pu, Xia Xiao, Shasha Lv, Daqing Ran, Qian Huang, Mingming Zhou, Qirong Lei, Lingshuang Kong, Qing Zhang

“…The METTL3-dependent regulation of DLG2 mRNA stability could be a critical factor in cervical cancer progression.…”
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TGFBR3 inhibits progression of papillary thyroid cancer by inhibiting the PI3K/AKT pathway and EMT by Hanrong Zhang, Junxin Chen, Xin Chen, Chuimian Zeng, Pengyuan Zhang, Jiewen Jin, Haipeng Xiao, Yanbing Li, Hongyu Guan, Hai Li

“…Transcriptome sequencing, quantitative real-time reverse transcription-polymerase chain reaction (qRT-PCR), and Western blotting were used to detect the underlying mechanism of TGFBR3 in PTC progression. …”
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Association of renin-angiotensin system genes polymorphism with progression of diabetic nephropathy in patients with type 1 diabetes mellitus by Ilić Vesna, Ilić Miroljub, Soldatović Ivan, Popović Srđan, Magić Zvonko

“…Diabetic nephropathy (DN) as a major microvascular complication of diabetes mellitus (DM) include a progressive increase in urinary albumin excretion in association with an increase in blood pressure and to end stage renal failure. …”
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The prognostic impact of maximal aortic diameter on acute type B aortic dissection progression in a Chinese population by Xianming Tang, Shuangfa Qiu, Xin Sun, Guifang Yang, Lijuan Sheng

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METTL3 mediates m6A methylation modification of ULBP2 and affects the progression of cervical cancer by Hongtao Ren, Yuting Wang, Jiao Yu, Lei An, Xiulong Ma, Jiyuan Pan

“…However, the precise molecular mechanism regulating CC progression through methyltransferase-like protein 3 (METTL3) and UL16 Binding Protein 2 (ULBP2) remains largely unknown. …”
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Dysregulation of miR-106a-5p/PTEN axis associated with progression and diagnostic of postmenopausal osteoporosis by Xiangjie Liu, Xiaogang Zhang, Meini Cen

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Interruption of the visual cycle in a novel animal model induces progressive vision loss resembling Stargardts Disease by Fabiana Sassone, Catherine Estay-Ahumada, Michel J. Roux, Dominique Ciocca, Paola Rossolillo, Marie-Christine Birling, Janet R. Sparrow, Diego Montenegro, David Hicks

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Molecular bases of muscular definition: the role of myostatin and proteinkinase β in progression of protein-energy waste in patients on hemodialysis by A. S. Kuzyarova, M. Z. Gasanov, M. M. Batyushin, O. V. Golubeva

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Fibroblast IRF7-mediated chondrocyte apoptosis affects the progression of collapse in steroid-induced osteonecrosis of the femoral head by Han Longfei, Fang Weihua, Han Mingli, Zhuang Zhikun, He Mincong, Wei Qiushi

“…Crystalline violet staining was used to observe the migration rate of fibroblasts, and flow cytometry was used to detect the apoptosis level of chondrocytes under co-culture conditions. …”
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Progressive iron overload in middle-aged mice impairs olfactory function, triggers lipid oxidation and induces apoptosis by Lin Deng, Lin Deng, Lin Deng, Qihui Luo, Qihui Luo, Yucong Liu, Yucong Liu, Yao Wang, Yao Wang, Zongliang Xiong, Zongliang Xiong, Hongping Wang, Lu Zhao, Lanlan Jia, Lanlan Jia, Riyi Shi, Chao Huang, Chao Huang, Zhengli Chen, Zhengli Chen

“…IntroductionThis study aims to investigate the progressive impact of chronic iron overload on the olfactory bulb, a region significantly affected in early neurodegenerative diseases like Parkinson’s and Alzheimer’s. …”
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Predictors for regression and progression of actively surveilled cervical intraepithelial neoplasia grade 2: A prospective cohort study by Laura Bergqvist, Anni Virtanen, Ilkka Kalliala, Ralf Bützow, Maija Jakobsson, Annu Heinonen, Karolina Louvanto, Joakim Dillner, Pekka Nieminen, Karoliina Aro

“…Complete regression (normal histology and/or normal or atypical squamous cells of undetermined significance (ASC‐US) cytology) was detected in 64.4.% (n = 132) while 16.1% (n = 33) of the lesions progressed to CIN grade 3 (CIN3) or worse including 31 CIN3 cases, one adenocarcinoma in situ and one cervical cancer case. …”
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Sialylated IgG expressed in triple-negative breast cancer cells promotes cancer progression by promoting glycolysis by Chenyang Hu, Shenghua Zhang, Fugang Duan, Xinmei Huang, Jing Huang, Zhu Zhu, Xiaoning Mo, Weiyan Xu, Lina Wu, Zhimin Fan, Xiaoyan Qiu

“…Results SIA-IgG was frequently detected in TNBC cells and was negatively associated with prognosis. …”
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Innovative modeling: a diet-induced quail model for progressive pathological changes in uric acid metabolism disorders by Yi Xu, Yu Wang, Fujun Gao, Chengjin Lu, Shujia Liu, Siying Chen, Xiaomeng Zhang, Zhijian Lin, Bing Zhang

“…The model effectively recapitulated three progressive pathological stages: (1) Hyperuricemia; (2) Hyperuricemia with urate nephropathy; and (3) Hyperuricemia with gouty arthritis. …”
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The sensory-motor auditory visual education (SAVE) program for adults with prior concussions: a prospective case study by Emily D. Drake, Angela S. Seckington, Stephanie G.B. Sullivan, Shannan Behrens

“…Results: Following the treatment program, 5 individuals showed significant (p < 0.05) improvements in various reported symptoms, significant (p < 0.05) improvements in recognizing colors further from the center of a target, and better detection of an auditory stimulus in the right ear. …”
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The role of errorful and errorless training on error detection and learning of tracking task by Ehsan Zareıan, Karen Baranı, Majid Arab, Mehdi Dastfal

“…This difference was in favor of the errorless training group and this group's progress in detecting errors was more than the errorful training group. …”
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Enabling sustainability by detecting early warning signs of corruption in government institutions by Pupung Purnamasari, Rudy Hartanto, Gugyh Susandy, Asep Kurniawan

“…This study aims to scientifically detect EWSC and recommend prevention strategies to accelerate progress to achieve SDGs. …”
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THE NATIONAL ONCOLOGICAL PROGRAM IMPLEMENTATION – EXPERIENCE IN THE VLADIMIR REGION (TO THE 70TH ANNIVERSARY OF THE REGIONAL CLINICAL ONCOLOGICAL DISPENSARY) by A. G. Zirin, E. A. Rumyantseva, K. V. Chirkov, M. N. Bulanov, G. V. Shatalova, Yu. L. Timofeev, A. V. Basharin, I. A. Konyukhov, A. V. Sheiko

“…Target indicators of the oncological program implementation by 2015 were established. They are: Increase of 5-year survival value of patients with malignant tumors after diagnosis date to 51.4%; Increase the number of malignant tumors early detection cases at the I–II stages up to 51%; Decrease the mortality rate of working age population to 99 per 100 000; Decrease of mortality within one year from the first time of cancer diagnosis to 27%. …”
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Salivary biomarkers: A promising avenue for advancing oral cancer detection by Yuvashree Chandrasekaran, L. Kayal, N. Aravindha Babu, Mukesh Kumar Dharmalingam Jothinathan, Archana Behera

“…This article will address recent progress in detecting saliva biomarkers including human DNA, mRNA and proteins that can be of diagnostic value in cancer. …”
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The effectiveness of health education programs on human immunodeficiency virus/sexually transmitted infection awareness among adolescent girls in Bagalkot by Simmy Gavel, Pooja Todalabagi, Rachel Sushmita Daniel, Basavraj Mannapur

“…They answered a questionnaire about HIV and STIs before the education program. After the program, the same questionnaire was given again 3 months later. …”
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