Diagnostic accuracy of SARS-CoV-2 antigen test in the pediatric population: A systematic review and meta-analysis by Cheng-Chieh Chen, Shih-Yen Chen, Shiuh-Bin Fang, Shou-Cheng Lu, Chyi-Huey Bai, Yuan-Hung Wang

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SKIN AVILABLE MASTOID AREA ON THE STAGE OF ITS STRAIN by D.S. Avetikov, D.V. Steblovskii, I.I. Starchenko

“…Also frequently in epitheliocytes piknotychni shriveled kernel was detected. The study of microscopic preparations of mastoid skin areas after stretching in the range of 20 mm and the emergence of a qualitatively new lesions in both the epidermis and the dermis can detect amplification. …”
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Oral PRI-002 treatment in patients with MCI or mild AD: a randomized, double-blind phase 1b trial by Janine Kutzsche, Nicoleta Carmen Cosma, Gunther Kauselmann, Friederike Fenski, Christine Bieniek, Tuyen Bujnicki, Marlene Pils, Oliver Bannach, Dieter Willbold, Oliver Peters

“…Furthermore, no significant changes were detected in p-tau, t-tau, Aβ 1-40, Aβ 1-42 and Aβ oligomers in CSF. …”
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MiR-506 suppresses proliferation, migration, and invasion of melanoma cells by modulating EMT and DNA damage homologous recombination repair pathway by LI Ting, XIANG Lijie, FU Laihua, HAO Mengze, LIU Xinyue, YANG Jilong

“…[Methods] The expression of miR-506 in 48 cases of fresh malignant melanoma tissues was detected by qRT-PCR. The expression of MET and DNA damage-related proteins in the tissues of 147 patients with malignant melanoma were detected by IHC. …”
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m6A-Methylated NUTM2B-AS1 Promotes Hepatocellular Carcinoma Stemness Feature via Epigenetically Activating BMPR1A Transcription by Li W, Zeng M, Ning Y, Lu R, Wei Y, Xu Z, Wei H, Pu J

“…As the most abundant modification in RNA, N6-methyladenosine (m6A) has been reported to be involved in HCC initiation and progression. However, whether m6A has oncofetal characteristics remains unknown.Methods: Gene expression in HCC tissues and cells was detected using qPCR. …”
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Prognostic role of epidermal growth factor receptors’ expression in patients with i-ii stage of non-small cell lung cancer by A.P. Kolesnik, A.I. Shevchenko, V.A. Tumansky, A.V. Evseev, M.A. Shishkin

“…However, even after surgical treatment disease progression develops in some patients, that denotes the biological diversity of patients with early stages of NSCLC. …”
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ZIP4 promotes glycolysis in cholangiocarcinoma cells by enhancing H3K4me3 modification and activating MYCN transcription by Jiwen WANG, Cheng ZHANG, Dexiang ZHANG, Xiaoling NI, Kun FAN, Houbao LIU

“…ObjectiveTo explore the mechanism by which zinc-regulated transporters, iron-regulated transporter-likeprotein 4 (ZIP4) regulates glycolysis and its impact on tumor progression in cholangiocarcinoma (CCA), providing a theoretical basis for targeted therapy of CCA. …”
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Colony size as the main driver of the evolution of song diversity and composition in weaverbirds by Harscouet-Commecy, Erwan, Adenot, Tohi, Thetiot, Alexandre, Bresciani, Nel, Oschadleus, Hans-Dieter, Covas, Rita, Rybak, Fanny, Doutrelant, Claire

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Plasma microRNA-15a/16-1 serves as a non-invasive indicator of liver fibrosis severity in individuals with chronic hepatitis B by Huan Wei, Yanhua Bi, Chunhong Liao, Yuehua Huang, Yifan Lian

“…Background: The lack of effective non-invasive diagnostic methods for liver fibrosis hinders timely treatment for chronic hepatitis B (CHB) patients, leading to the progression of advanced liver disease. Circulating microRNAs offer a non-invasive approach to fibrosis assessment. …”
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Features of Glucose Homeostasis and Blood Lipid Spectrum in Patients with Nonalcoholic Fatty Liver Dis­ ease Depending on the Obesity Degree by Korniichuk I., Khukhlina O., Vivsyannuk V., Yatskevych O., Kovalska І.

“…Among the complications of obesity, non­alcoholic fatty liver disease, the occurrence of which significantly reduces the life quality of patients, contributes to the development of glucose tolerance disorders, development and progression of hepatic­cellular insufficiency. The aim of the study. …”
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The Orthopedic Strategy for Patients with Larsen Syndrome by Ali Al Kaissi, Alexander Gubin, Sergey Ryabykh, Vasileios Dougales, Hamza Al Kaissi, Susanne Gerit Kircher, Franz Grill

“…A less serious cervical spine malformation was detected in two children who presented with progressive acute-angle cervico and cervico-thoracic kyphosis. …”
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Verification of biological markers of subacute cutaneous lupus erythematosus via TMT labelling proteomics combined with transcriptome data by Yuan Tao, Guo Hua, Sun Min, Lu Xiao-hong, Jiang Jia-hui, Tang Biao, He Cai-feng, Zhang Cheng, Ci Chao, Wu Jian-ping

“…ROC curve analysis demonstrated that serum levels of IFI44 and EPSTI1 could differentiate SCLE from SLE with an area under the curve (AUC) of 0.898 and 0.847, respectively.Conclusions The IFI44 and EPSTI1 proved to be closely involved in the progression from SCLE to SLE, and can represent new candidate diagnostic molecular markers of occurrence and progression of SCLE.…”
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CD66b⁺ Tumor-Infiltrating Neutrophil-like Monocytes as Potential Biomarkers for Clinical Decision-Making in Thyroid Cancer by Hamdullah Yanik, Ilgin Demir, Ertugrul Celik, Ece Tavukcuoglu, Ibrahim Burak Bahcecioglu, Adile Begum Bahcecioglu, Mehmet Mert Hidiroglu, Sumeyra Guler, Nese Ersoz Gulcelik, Mehmet Ali Gulcelik, Kerim Bora Yilmaz, Gunes Esendagli

“…Elevated levels of this novel subtype of immune cells in malignant tissues suggest their role in tumor progression and their utility in enhancing diagnostic accuracy. …”
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Genetic characteristics involving the PD-1/PD-L1/L2 and CD73/A2aR axes and the immunosuppressive microenvironment in DLBCL by Tingting Zhang, Zhenzhen Zhang, Xiubao Ren, Jin He, Zhengzi Qian, Bin Meng, Lei Jiao, Hengqi Liu, Lanfang Li, Lihua Qiu, Shiyong Zhou, Wenchen Gong, Huilai Zhang, Xianhuo Wang

“…Background Targeting the PD-1/PD-L1/L2 (programmed cell death protein 1/programmed cell death ligand 1/ligand 2) pathway combined with other immunosuppressive signalings, such as CD73/A2aR (A2a adenosine receptor) adenosine signaling, has emerged as a promising strategy for cancer treatment. …”
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Individualized home training in head and neck cancer patients is safe and has positive short- and medium-term effects –results of a multicenter, single-arm intervention trial (OSHO... by Sabine Felser, Lars A. Bonke, Änne Glass, Daniel Strüder, Jana Stolle, Susann Schulze, Susann Schulze, Markus Blaurock, Anke Steinmetz, Julia Daunheimer, Ursula Kriesen, Christina Grosse-Thie, Christina Grosse-Thie, Christian Junghanss

“…Some short-term effects could be detected medium-term.DiscussionPhysical activity level improved despite an unchanged activity duration suggesting an increased training intensity. …”
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LKB1 dictates sensitivity to immunotherapy through Skp2-mediated ubiquitination of PD-L1 protein in non-small cell lung cancer by Wei Liu, Dong Wang, Qing Miao, Peilin Chen, Hongbing Liu, Jiawen Lv, Jie Yin, Jian Feng, Yong Song, Tangfeng Lv, Mingxiang Ye, Wenjie Yan, Liting Lv, Sutong Zhan

“…The LKB1 mutant NSCLC was refractory to almost all the antitumor treatments, including programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) blockade therapy. …”
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B and T lymphocyte attenuator (BTLA) and PD-1 pathway dual blockade promotes antitumor immune responses by reversing CD8+ T-cell exhaustion in non-small cell lung cancer by Yang Zhang, Yang Zhang, Yang Yang, Yang Yang, Yuanyuan Zeng, Yuanyuan Zeng, Qiuxia Qu, Dan Shen, Chuanyong Mu, Wei Lei, Meiqin Su, Jingyu Mao, Lirong Gao, Zeyi Liu, Zeyi Liu, Cheng Chen, Jian-an Huang, Jian-an Huang

“…BackgroundImmunotherapies targeting the programmed cell death 1 (PD-1)/programmed death ligand 1 (PD-L1) have shown great promise for a subset of patients with non-small cell lung cancer (NSCLC). …”
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Expert consensus on the evaluation and management of high-risk indeterminate pulmonary nodules by Yang Dawei, Stephan Lam, Kai Wang, Zhou Jian, Zhang Xiaoju, Wang Qi, Zhou Chengzhi, Zhang Lichuan, Bai Li, Wang Yuehong, Li Ming, Sun Jiayuan, Li Yang, Fengming Kong, Haiquan Chen, Ming Fan, Xuan Jianwei, Fred R. Hirsch, Charles A. Powell, Bai Chunxue

“…The MIoT technology, which has the potential to realize “simplification of complex problems, digitalization of simple problems, programming of digital problems, and systematization of programming problems”, can promote the homogeneous evaluation of pulmonary nodules by enhancing both the sensitivity and the specificity of detecting early-stage lung cancer, in order to avoid delayed diagnosis and overtreatment. …”
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Diagnostic value of Epstein – Barr virus DNA quantification in blood leukocytes in children with infectious mononucleosis by M. I. Popkova, E. N. Filatova, E. A. Soboleva, D. A. Bryzgalova, E. A. Kulova, N. A. Sakharnov, O. V. Utkin

“…Threshold was determined based on VL data from children with active and latent EBV infection. The R program and the RStudio environment were used for satistic analysis.Results. …”
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Promoting oral health and fighting malnutrition in the Sahel region of Burkina Faso: the integrated nutrition strategy of the ‘projet de sensibilisation et de renforcement des capa... by Hadissa Tapsoba, Peegdsom Simplice Assomption Yameogo, Souleymane Bougoum, Achille Ilboudo

“…The nutrition component targets pregnant and breastfeeding women as well as children aged six to 23 months via integrated strategies: awareness-raising via community groups, malnutrition screening, referral of detected cases to health centres and distribution of enriched rations of infant flour. …”
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