The prognostic value of KRAS mutation by cell-free DNA in cancer patients: A systematic review and meta-analysis. by Rongyuan Zhuang, Song Li, Qian Li, Xi Guo, Feng Shen, Hong Sun, Tianshu Liu

“…Literature searches of Cochrane Library, EMBASE, PubMed and Web of Science were performed to identify studies related to KRAS mutation detected by cfDNA and survival in cancer patients. …”
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The Significance of Carbohydrate Antigen 19-9, Carcinoembryonic Antigen, Calcium and Zinc as Biomarkers in Sera of Colorectal Cancer Patients by Fenik Ahmed Nadir, Zeyan Abdullah Ali

“…The aim of this study is to detect serum concentrations of carbohydrate antigen 19-9, carcinoembryonic antigen, calcium, and zinc in CRC. …”
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Impact of sight and hearing loss in patients with Norrie disease: advantages of Dual Sensory clinics in patient care by Jane C Sowden, Corné J Kros, Tony Sirimanna, Waheeda Pagarkar, Ngozi Oluonye, Robert H Henderson

“…While all affected patients are born blind, or lose their vision in infancy, progressive sensorineural hearing loss develops in the majority of cases and is typically detected in the second decade of life. …”
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Infectiousness of Leishmania major to Phlebotomus papatasi: differences between natural reservoir host Meriones shawi and laboratory model BALB/c mice. by Barbora Vojtková, Tomáš Bečvář, Lenka Pacáková, Daniel Frynta, Nalia Mekarnia, Kamal Eddine Benallal, Petr Volf, Jovana Sádlová

“…Moreover, this study highlights the importance of incorporating natural host models in research, as the dynamics of disease progression and transmission parameters can differ significantly between natural hosts and standard laboratory models.…”
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Proteomic Profiling of Human Peripheral Blood Cell Targets of IgG Induced by SARS-CoV-2: Insights into Vaccine Safety by Nicolle Rakanidis Machado, Lais Alves do Nascimento, Beatriz Oliveira Fagundes, João Vitor da Silva Borges, Fabio da Ressureição Sgnotto, Isabella Siuffi Bergamasco, Juliana Ruiz Fernandes, Thalyta Nery Carvalho Pinto, Anna Julia Pietrobon, Gil Benard, Maria Notomi Sato, Jefferson Russo Victor

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Functional Imaging of Liver Cancer (FLIC): Study protocol of a phase 2 trial of 18F-DCFPyL PET/CT imaging for patients with hepatocellular carcinoma. by Esther Mena, Joanna Shih, Joon-Yong Chung, Jennifer Jones, Atoosa Rabiee, Cecilia Monge, Baris Turkbey, Liza Lindenberg, Kilian E Salerno, Michael Kassin, Brad Wood, Jonathan Hernandez, Roberto Maass-Moreno, Babak Saboury, Neha Jakhete, Jason K Molitoris, Keith R Unger, Peter L Choyke, Freddy E Escorcia

“…Participants will be followed for 5-years to assess for progression-free-survival. The primary endpoint is the positive predictive value of 18F-DCFPyL-PET for HCC as confirmed by histopathology. …”
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Integrated Analysis of Cell-Free DNA and Novel Protein Biomarkers for Stratification and Therapy Monitoring in Stage IV Pancreatic Cancer: A Preliminary Study by Saskia Hussung, Maria E. Hess, Elham Bavafaye Haghighi, Uwe A. Wittel, Melanie Boerries, Ralph M. Fritsch

“…Highly sensitive single-target ddPCR assays were employed to detect and quantify <i>KRAS</i>^mut cfDNA. …”
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Effect of human papillomavirus infection on semen quality and assisted reproductive technology outcomes: a prospective observational cohort study by Sara Stigliani, Erika Coppo, Maria Bonaffini, Elena Maccarini, Francesca Bovis, Ida Casciano, Claudia Massarotti, Fausta Sozzi, Anna Marchese, Paola Scaruffi, Paola Anserini

“…Twenty-three HPV types were detected and 69.5% of positive samples presented at least one high risk (HR)-HPV genotype. …”
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Modifying reaction time tasks parameters in the automated IntelliCage identifies heightened impulsivity and impaired attention in the 3xTg-AD model of Alzheimer’s disease by Jessica M. Judd, Wendy Winslow, Ian McDonough, Faizan Mistry, Ramon Velazquez, Ramon Velazquez, Ramon Velazquez

“…Each of the four corners of a cage contains doors to manipulate access to water, visual LED cues, and a valve allowing administration of an air puff. Previously, we detected significant impairments in 3xTg-AD mice in the IntelliCage, however a high failure rate and genotypical differences in water motivation were observed.MethodsHere, we implemented an IntelliCage paradigm where mice underwent progressively more difficult reaction time tasks to assess attention and impulsivity, behaviors mediated by the prefrontal cortex. …”
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The expression of renin-angiotensin system components in human carotid plaque by Kolaković Ana, Bundalo Maja, Đurić Tamara, Končar Igor, Stanković Aleksandra, Živković Maja

“…In 56.06% of plaque samples, no expression of ACE2 mRNA was detected. Among the plaques where ACE2 mRNA expression was detected, its expression level was higher in females with the HoP phenotype compared to females with the HerP phenotype (p < 0.001). …”
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Probabilistic risk assessment of emerging EU-regulated fragrance allergens in household and personal care products by Hogeon Lee, Eun Chul Pack, Ye Ji Koo, Dae Yong Jang, Do Hyeon Lee, Tae Hyeon An, Gyeong Tae Kim, Seung Ha Lee, Kyung Min Lim, Dalwoong Choi

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Anti-influenza effects of Aloe vera gel on MDCK cells: protective efficacy against ultraviolet-C exposure and analysis of biochemical characteristics and microbial activities by Rasha A. Al-Eisa, Rokayya Sami, Ruqaiah I. Bedaiwi, Roqayah H. Kadi, Suzan A. Abushal, Doaa Mahmoud Johari, Afnan M. Alnajeebi, Reham M. Algheshairy, Abeer A. Abu-Zaid, Sami A. Al-Dhumri

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Radon exhalation rate from the latex pillows and its potential exposure to users by Phachirarat Sola, Kanokporn Boonsirichai, Santi Raksawong, Ritiron Samran, Pimprapa Chaijak, Hirofumi Tazoe, Chutima Kranrod, Rawiwan Kritsananuwat, Sattawat Jongjitklang, Vichai Puripunyavanich, Masahiro Hosoda, Waleeporn Pongkua, Shinji Tokonami

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Some growth factors in neoplastic tissues of brain tumors of different histological structure by O. I. Kit, E. M. Frantsiyants, E. E. Rostorguev, I. V. Balyazin-Parfenov, N. D. Cheryarina, L. S. Kozlova, Yu. A. Pogorelova

“…The level of growth factor was detected in the samples of tumor tissue and regions immediately adjacent to the tumor foci (peritumoral area) by the method of immunoassay and using standard test systems. …”
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Characteristics of clinical, laboratory, and immunological manifestations in patients with anticentromere antibody-associated Sjögren's disease by B. D. Chaltsev, V. I. Vasilyev, S. G. Palshina, A. V. Torgashina, E. V. Sokol, Yu. I. Khvan, E. B. Rodionova, T. N. Safonova, S. V. Lapin, O. Yu. Tkachenko, A. V. Mazing

“…ACA-associated SD is an independent disease subtype characterized by an increased risk for SDS, PBC, and MALT lymphomas and by a low frequency of the systemic manifestations and laboratory signs characteristic of classical SD. Regardless of the detected type of antibodies and the presence or absence of extraglandular manifestations, damage to the salivary and lacrimal glands progresses in SD, which often leads to lymphomas; therefore, the therapy that may prevent this complication should be initiated as soon as possible after SD diagnosis. …”
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Implementation and Evaluation of a Best Practice Advisory to Reduce Inequities in Technology Use for People With Type 1 Diabetes: Protocol for a Mixed Methods, Nonrandomized Contro... by Nestoras Mathioudakis, Risa Wolf, Abha Choudhary, Georgia Davis, Mary Pat Gallagher, Meenal Gupta, Manmohan Kamboj, Nicole Rioles, Emma Ospelt, Susan Thapa, Ruth S Weinstock, Trevon Wright, Osagie Ebekozien

“…The primary outcome is the progression in ADT use from the baseline to postintervention periods. …”
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Peptides based on the interface of hnRNPA2B1-transthyretin complex repress retinal angiogenesis in diabetic retinopathy by Yixiu Chen, Lu Ye, Shujing Cui, Jun Shao, Yu Xin

“…In vivo studies using DR model rat revealed that the intravitreal administration of THIP-4 significantly mitigated retinal leakage, capillary decellularization, pericyte loss, fibrosis, and gliosis during DR progression. Conclusion Our findings demonstrated that under hyperglycemia, THIP-4 suppressed DR progression via the STAT4/miR-223-3p/FBXW7 and Notch1/Akt/mTOR axes both in vitro and in vivo. …”
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Early expression of osteopontin glycoprotein on the ocular surface and in tear fluid contributes to ocular surface diseases in type 2 diabetic mice. by Ananya Datta, Xin Yi Li, Manshul Nagpaul

“…<h4>Conclusions</h4>Elevated OPN levels were detected early post-T2D induction in diabetic WT and db/db mice corneas without initial subclinical changes. …”
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Identification of tRF-29-79MP9P9NH525 as a biomarker and tumor suppressor of gastric cancer via regulating KIF14/AKT pathway by Jiaxin Ge, Ji Dai, Haoqiang Ji, Jie Guo, Xiaoban Shen, Desen Sun, Qiang Chen, Pan Chen, Guoliang Ye, Junming Guo, Shuangshuang Zhang

“…In conclusion, tRF-29 inhibited GC progression by combining with Ago2 and regulated AKT/P27 pathway by silencing KIF14 expression. …”
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Conventional in vitro fertilization enhances preimplantation genetic testing for aneuploidy outcomes in couples with non-male factor infertility by Xiaolan Li, Qian Li, Yajie Chang, Shujing He, Yanfang Wang, Xiaoyan Liang, Zhiqiang Zhang

“…Baseline characteristics, including parental age, AMH, antral follicle count (AFC), BMI, progressive motile sperm count, and PGT indications, were comparable between groups. …”
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