Clinical Outcomes of Passive Sensors in Remote Monitoring: A Systematic Review by Essam Rama, Sharukh Zuberi, Mohamed Aly, Alan Askari, Fahad M. Iqbal

“…These technologies demonstrated feasibility and ecological validity in capturing continuous, real-world health data and offer a unified framework for enhancing patient care through three main applications: monitoring chronic disease progression, detecting acute health deterioration, and supporting therapeutic interventions. …”
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Genome-Wide Characterization of RNA Editing Sites in Primary Gastric Adenocarcinoma through RNA-seq Data Analysis by Javad Behroozi, Shirin Shahbazi, Mohammad Reza Bakhtiarizadeh, Habibollah Mahmoodzadeh

“…Totally, 12362 high-confidence adenosine to inosine RNA editing sites were detected across all samples. Of these, 12105 and 257 were known and novel editing events, respectively. …”
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Investigation of the mechanism by which miR-223-3p inhibits reflux esophagitis through targeting the NLRP3 inflammasome by Shuying Lin, Binbin Zheng, Ruchen Wu, Qiuli Wu, Xiangbo Chen

“…Overexpression and inhibition techniques were used to study the effects of miR- 223 - 3p on the NLRP3 inflammasome. qPCR and Western blot analyses were employed to detect the expression of related inflammatory factors, and flow cytometry was used to assess cell apoptosis and cell cycle changes. …”
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Identification of STAT5A and STAT5B target genes in human T cells. by Takahiro Kanai, Scott Seki, Jennifer A Jenks, Arunima Kohli, Trupti Kawli, Dorrelyn Patacsil Martin, Michael Snyder, Rosa Bacchetta, Kari C Nadeau

“…The new identification of these genes regulated by STAT5A and/or STAT5B has major implications for understanding the pathophysiology of cancer progression, neural disorders, and immune abnormalities.…”
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Single or multiple arterial grafting to design a coronary bypass: a retrospective study by A. V. Frolov, N. I. Zagorodnikov, R. S. Tarasov, E. V. Grigoriev

“…The most common cause for the failure of anastomoses was competitive flow (most frequently registered in the anastomoses between left internal thoracic artery and left anterior descending artery, left internal thoracic artery and diagonal branches of left anterior descending artery, right internal thoracic artery and left anterior descending artery, and between right internal thoracic artery and right coronary artery), poor distal bed (most frequently revealed in the anastomosis between left internal thoracic artery and obtuse marginal artery, saphenous vein and diagonal branches of left anterior descending artery, saphenous vein and obtuse marginal artery, and between saphenous vein and right coronary artery), progression of atherosclerosis in combination with poor distal bed (most frequently detected in the anastomosis between right internal thoracic artery and obtuse marginal artery), and combination of poor distal bed, competitive flow, and graft degeneration (most frequently found in the anastomoses between radial artery and obtuse marginal artery and between radial artery and right coronary artery). …”
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The QP509L and Q706L superfamily II RNA helicases of African swine fever virus are required for viral replication, having non-redundant activities by Ferdinando B. Freitas, Gonçalo Frouco, Carlos Martins, Fernando Ferreira

“…The immunoblot analysis revealed that both protein co-localized in the viral factories at 12 h post infection, however, QP509L was also detected in the cell nucleus. Finally, siRNA assays uncover the relevant role of these proteins during viral cycle progression, in particular, for the late transcription, genome replication, and viral progeny (a reduction of infectious particles up to 99.4% when siRNA against QP509L was used and 98.4% for siRNA against Q706L). …”
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Knockdown of hsa_circ_0001275 reverses dexamethasone-induced osteoblast growth inhibition via mediation of miR-377/CDKN1B axis. by Yan Xu, Liqin Sun, Juncheng Hu, Sai Xu

“…In addition, dysfunction of osteoblasts can lead to the progression of osteoporosis. Circular (circ)RNAs are involved in various types of diseases, including osteoporosis. …”
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Analysis of laboratory parameters in patients with pemphigus vulgaris complicated with infections by ZHAO Shiqi, MIAO Qing, ZHANG Xiaohan

“…[Objective] To analyze the association between laboratory parameters and pemphigus vulgaris (PV) complicated with infections, aiding in assessment of disease progression and prevention of infection. [Methods] Clinical data and laboratory test results were collected from 155 PV inpatients, including white blood cell count (WBC), neutrophil count (NEU), lymphocyte count (LYM), platelet count (PLT), C-reactive protein (CRP), fibrinogen (FIB), albumin (ALB), globulin (GLB), immunoglobulin E (IgE), immunoglobulin G (IgG), immunoglobulin A (IgA), immunoglobulin M (IgM), complement C3, complement C4, anti-Dsg1 antibody, and anti-Dsg3 antibody. …”
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ATXN2-Mediated PI3K/AKT Activation Confers Gastric Cancer Chemoresistance and Attenuates CD8+ T Cell Cytotoxicity by Qi Wang, Tianyu Cao, Xiaohui Zhang, Juan Hui, Chen Wang, Wenyao Zhang, Pei Wang, Yun Zhou, Shuang Han

“…As one of the primary therapeutic choices, chemotherapy is widely adopted for progressive gastric cancer (GC), but the development of chemoresistance has limited chemotherapy efficacy and partly contributes to poor prognosis. …”
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Variations in Semen Quality and Potential for Frozen Semen Production in Aceh Cattle by E. Sophian, S. Said, M. A. Setiadi, R. I. Arifiantini

“…The total sperm motility of bull 211710 was higher than that of the other bulls. The highest progressive motility was observed in bulls 211710 and 211605, and the highest intact DNA was detected in bulls 211710 and 211605. …”
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Case Report: Synchronous pancreatic sarcomatoid carcinoma and gastric cancer: a case study with literature review by Genlin Lu, Jinming Tu, Renya Jiang

“…However, these markers were predominantly increased in the presence of multiple liver metastases.Malnutrition and progressive disease occurred despite the adoption of EN plus PN and best supportive care, and the patient died on postoperative day 107.ConclusionsSynchronous SCP and gastric cancer are first reported in this study. …”
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Diagnostic value of the correlation between urinary MDM2 and podocyte mitotic catastrophe in diabetic kidney disease by Li Xu, Xiuli Guo, Wen Gan, Linhong Yao, Jianing Wang, Qi Li, Qiuling Fan

“…Abstract Background Podocytic injury and shedding are critical events in the progression and prognosis of diabetic nephropathy (DN). …”
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Altered spontaneous brain activity in primary open angle glaucoma: a resting-state functional magnetic resonance imaging study. by Yinwei Song, Ketao Mu, Junming Wang, Fuchun Lin, Zhiqi Chen, Xiaoqin Yan, Yonghong Hao, Wenzhen Zhu, Hong Zhang

“…Spontaneous brain activity may play a role in POAG initiation and progression.…”
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Profile of Ofatumumab in the Treatment of Multiple Sclerosis: Design, Development and Place in Therapy by Awada Z, Hameed N, Harel A

“…Clinical trials have consistently shown its effectiveness in significantly reducing annualized relapse rates, MRI-detected lesion activity, and disability progression when compared to teriflunomide, a standard therapy for MS. …”
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Novel CDK2/CDK9 inhibitor fadraciclib targets cell survival and DNA damage pathways and synergizes with encorafenib in human colorectal cancer cells with BRAF(V600E) by Md Mohiuddin, Vanda Póvoa, Rita Fior, Frank A. Sinicrope

“…Abstract The oncogenic BRAF(V600E) mutation activates the ERK1/2 pathway and is detected in 10% of human colorectal cancers (CRCs) where it is associated with poor prognosis. …”
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Superiority of pan-immune inflammation value, systemic inflammation index, and CALLY scores prognostic value for mortality of ischemic stroke patients followed in intensive care un... by Gülsüm Altuntaş, Rahmet Yıldırım, İsmail Demirel

“…Abstract Aims The Inflammatory response plays an important role in the pathophysiology and prognosis of ischemic stroke. Hyperinflammation progresses with aggravation of brain damage and deterioration in clinical status. …”
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Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host. by Mariana Varela, Esther Schnettler, Marco Caporale, Claudio Murgia, Gerald Barry, Melanie McFarlane, Eva McGregor, Ilaria M Piras, Andrew Shaw, Catherine Lamm, Anna Janowicz, Martin Beer, Mandy Glass, Vanessa Herder, Kerstin Hahn, Wolfgang Baumgärtner, Alain Kohl, Massimo Palmarini

“…These virus-induced acute lesions are useful in understanding the progression from vacuolation to porencephaly and extensive tissue destruction, often observed in aborted lambs and calves in naturally occurring Schmallenberg cases. …”
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Long non‐coding RNA XIST alleviates sepsis‐induced acute kidney injury through inhibiting inflammation and cell apoptosis via regulating miR‐155‐5p/WWC1 axis by Lei Wang, Qiu‐Mei Cao

“…ELISAs were conducted to detect the concentrations of proinflammatory cytokines. …”
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Cardamonin suppresses mTORC1/SREBP1 through reducing Raptor and inhibits de novo lipogenesis in ovarian cancer. by Peiguang Niu, Danyun Li, Huajiao Chen, Yanting Zhu, Jintuo Zhou, Jinhua Zhang, Ying Liu

“…Metabolic reprogramming is a hallmark of cancer and de novo lipogenesis (DNL) accelerates the progression of ovarian cancer. In this study, we investigated the effects of cardamonin, a natural compound potential to suppress various malignancies, on the lipid anabolism in ovarian cancer. …”
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Smartphone-based Infrared Thermography – A Novel Approach to Evaluate the Treatment Effect of Revascularization Procedure in Peripheral Arterial Disease Patients by Abinash Chihnara, Santosh Upadhyaya, Sr. Raypattanaik Niladri Mohan, Sashi Tandan, M Karthik, Gokula Krishnan Hari, Ujjwal Gorsi, Lileswar Kaman, Ajay Savlania

“…Background: Peripheral Arterial Disease (PAD) is a progressive vascular disorder that compromises blood flow to the extremities, leading to ischemic symptoms such as claudication, rest pain, and tissue loss. …”
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