Diagnostic value of miR-193a-5p in severe pneumonia and its correlation with prognosis by Xiaoji Su, Lijuan Zhu, Jiajia Zhuo, Shihai Zhang

“…Abstract Background Severe pneumonia is a common disease in children, with rapid progression and easy complications of respiratory failure, endangering the lives of children. …”
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Association between dietary fiber intake and chronic kidney disease in adults with and without hypertension in the United States: a cross-sectional study of NHANES 2009–2020 by Chao Zhang, Weimin Yan, Xun Sun, Fansen Lin

“…However, this correlation was not detected in the nonhypertensive group (OR = 0.99, 95% CI: 0.98–1.01, p = 0.285). …”
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Identification of FANCG as a prognostic factor for prostate cancer by Wenlong Gao, Peng Liu, Han Xinyue, Yuanjie Niu, Wu Yi

“…Quantitative real-time polymerase chain reaction (qPCR) was utilized to detect the expression levels of hub genes (MCM7, MCM5, POLD1, POLA2, LIG1) associated with FANCG. …”
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Genetic Polymorphism of TLR-4 and CD-14 in Patients with Chronic Prostatitis by Worood Ali Mukheef Al-Jobouri, Mohammed A. K. Al-Saadi, Wadhah Adnan Abbas Al-Marzooq

“…It is recognized to be associated with innate immunity since several cytokines are implicated in the occurrence and progression of Chronic abacterial prostatitis/chronic pelvic pain syndrome. …”
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Inhibition of neuroinflammation by GIBH-130 (AD-16) reduces neurodegeneration, motor deficits, and proinflammatory cytokines in a hemiparkinsonian model by Maria E. Bianchetti, Ana Flavia F. Ferreira, Luiz R. G. Britto

“…Here, for the first time, we sought to comprehend the potential impact of orally administered AD-16 in mitigating neurodegeneration and subsequent disease progression in PD. To accomplish this, 6- hydroxydopamine (6-OHDA) unilateral striatal injections were employed to induce a PD model in male C57BL/6 mice. …”
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Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules. by Xiaolin Xiao, Aida Moreno-Moral, Maxime Rotival, Leonardo Bottolo, Enrico Petretto

“…We applied our method to genome-scale and multi-tissue transcriptomic datasets from rats (microarray-based) and humans (mRNA-sequencing-based) and identified several common and tissue-specific subnetworks with functional significance, which were not detected by other methods. In humans we recapitulated the crosstalk between cell-cycle progression and cell-extracellular matrix interactions processes in ventricular zones during neocortex expansion and further, we uncovered pathways related to development of later cognitive functions in the cortical plate of the developing brain which were previously unappreciated. …”
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Experience of using the interleukin-6 inhibitor olokizumab in patients with rheumatoid arthritis in real-life clinical practice (based on data from Tyumen Regional Rheumatology Cen... by I. M. Patrikeeva, Yu. A. Lushpaeva, N. V. Knaub, E. A. Ustinova, O. A. Belikov, M. B. Dolgikh, T. Yu. Malysheva

“…During these periods, there was no radiological progression of RA against the background of OKZ therapy. …”
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Glutamate activates the MAPK pathway by inhibiting LPAR1 expression and promotes anlotinib resistance in thyroid cancer by Bin Liu, Ying Peng, Yanjun Su, Chang Diao, Liansheng Cha, Ruochuan Cheng

“…Conclusion Our study revealed that glutamate promotes the progression of malignant biological behavior in TC cell lines and TC-anlotinib-resistant cell lines. …”
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Characterization of Primary Cilia Formation in Human ESC-Derived Retinal Organoids by Ke Ning, Ziming Luo, Tia J. Kowal, Matthew Tran, Rishab Majumder, Trent M. Jarin, Albert Y. Wu, Jeffrey L. Goldberg, Yang Sun

“…Amacrine cells in retinal organoids retain cilia throughout development, whereas RGC ciliation gradually and progressively decreases with organoid maturation.…”
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Role of insulin-like growth factor, pro-inflammatory and anti-inflammatory cytokines, transcription factors and adipokines in development of hepatocellular carcinoma in metabolic s... by O. V. Smirnova, F. A. Gershkoron

“…Activation of PAI-1 inhibits the progression of HCC through PPARγ stimulation. Adiponectin may be a prognostic marker in HCC, with a lower serum concentration positively correlated with worse prognosis.…”
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N-Stearoyl-L-Tyrosine Inhibits the Senescence of Neural Stem/Progenitor Cells Induced by Aβ1–42 via the CB2 Receptor by Wen-Qing Li, Ze-jian Wang, Sha Liu, Yue Hu, Ming Yin, Yang Lu

“…Alzheimer’s disease, one of the neurodegenerative diseases, shows the progressive senescence of neural progenitor/stem cells. …”
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Structural basis of human ABCC4 recognition of cAMP and ligand recognition flexibility by Xuepeng Wen, Kaixue Si, Dantong Zhu, Anqi Zhang, Changyou Guo, Minghui Li, Weiming Tian

“…Abstract Background ABCC4 (ATP-binding cassette sub-family C member 4) is a transporter protein that is primarily localized to the plasma membrane, and its efflux activity is associated with the progression of various cancers and the development of drug resistance. …”
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IDH mutation and MGMT methylation status in glioblastoma and other gliomas patients: a Russian retrospective cohort study by Moez Eid, Dema Alset, Nataliya Timoshkina, Dmitriy Gvaldin, Eduard Rostorguev, Sergey Kavitskiy, Inna Novikova

“…Patients with mutated IDH gene have a significantly higher progression-free survival (PFS) and overall survival (OS) rates than those with wild-type genes. …”
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Spatial orientation tasks show moderate to high accuracy for the diagnosis of mild cognitive impairment: a systematic literature review by Raquel Quimas Molina da Costa, José Eduardo Pompeu, Larissa Alamino Pereira de Viveiro, Sonia Maria Dozzi Brucki

“…Abstract Spatial disorientation has been observed in mild cognitive impairment (MCI) and is associated with a higher risk of progression to Alzheimer's disease (AD). However, there is no gold standard assessment for spatial orientation and paper-and-pencil tests lack ecological validity. …”
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A-to-I RNA edited POLA2 attains carcinogenesis in prostatic cancer by impeding immune infiltration and upregulating BTBD7 by Shengyi Lin, Hang Huang, Yeping Li, Yongyong Lu, Tingyu Ye

“…Adenosine (A)-to-inosine (I) RNA editing, contributing to nearly 90% of all editing events in human, has been reported to contribute to pathogenesis and progression of cancer. Here, we aimed to elaborate the role and mechanism of A-to-I-edited POLA2 in PCa. …”
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Epigenetic silencing of TFPI-2 in canine diffuse large B-cell lymphoma. by Serena Ferraresso, Silvia Bresolin, Arianna Aricò, Stefano Comazzi, Maria Elena Gelain, Fulvio Riondato, Luca Bargelloni, Laura Marconato, Geertruy te Kronnie, Luca Aresu

“…In particular, hypermethylation of CpG islands in the promoter region of tumor suppressor genes is a well-known mechanism of gene silencing that contributes to cancer development and progression. Tissue factor pathway inhibitor 2 (TFPI-2) is a tumor suppressor involved in invasiveness inhibition. …”
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Genetic Profiling in Chronic Lymphocytic Leukemia: The Role of TP53 Mutations and IGHV Status in Treatment Decision-Making – A Case Report by Kateryna Khurdepa, Oksana Karnabeda

“…These genetic variations significantly affect disease progression, treatment choice, and response to therapy. …”
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Low-dose radiation ameliorates doxorubicin-induced renal injury via reducing oxidative stress and protecting mitochondrial function. by Mengmeng Chen, Kang He, Kai Wang, Yibo Cai, Zhaohui Ying, Xueting Li, Yating Liu, Liting Xiang, Pingping Yang, Hongjuan Wu, Jian Jiang

“…Histological analysis, immunohistochemical analysis, immunofluorescence analysis and western-blotting were used to detect the related indicators. Research data was showed as mean ±SD and tested by One-way ANOVA. …”
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The Novel Action of miR-193b-3p/CDK1 Signaling in HCC Proliferation and Migration: A Study Based on Bioinformatic Analysis and Experimental Investigation by Xue Pang, Wei Wan, Xingxing Wu, Yu Shen

“…A growing number of novel targets underlying HCC pathophysiology have been detected using microarray high throughput screening platforms. …”
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Exploring ultrasound-induced free radical formation: A comparative study in water and sour cherry juice using glutathione and terephthalic acid indicators by Nursena Aktı, Semanur Yildiz

“…This study offers key insights into how ultrasound conditions affect FR formation in water and SCJ media by stabilizing them in detectable forms.…”
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