E2F8-induced GRPEL2 promoted colorectal cancer progression via targeting TIGAR by Cheng Song, Lei Zhao, Jing Deng, Li Wang, Min Mao, Siyuan Peng, Wei Tang

“…The exact function of GRPEL2 -driven mitochondrial regulation and CRC progression have not been elucidated. Methods RNA-seq data from TCGA database was analyzed to identify biomarkers and therapeutic targets of CRC. …”
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S100A11 as an immune-related exosomal driver of colorectal cancer progression: a novel diagnostic biomarker by Haibo Wang, Rongchao He, Deng Liu, Jun He, Zhong Shen

“…Despite advancements in diagnostic and therapeutic strategies, early detection and effective treatment remain major challenges. …”
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ɑ1,3-mannosyltransferase promotes the malignant progression of bladder cancer through activating TNF signaling pathway by Mulin Liu, Jingyang Zhang, Siqi Zhu, Wenjun Jiang, Yu Yan, Qin Zheng, Shijun Li

“…Conclusions ALG3 contributed to BCa progression via CD44 N-glycosylation and TNF pathway, positioning it as a promising serum glycobiomarker, a feasible therapeutic target, and a valuable reference for personalized and precision medicine in BCa.…”
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Novel machine learning paradigms-enabled methods for smart building operations in data-challenging contexts: Progress and perspectives by Fan Cheng, Lei Yutian, Mo Jinhan, Wang Huilong, Wu Qiuting, Cai Jiena

“…This review aims to present the progress and perspectives on the effective utilization of novel machine learning paradigms for three major building energy management tasks, i.e., building energy predictions, fault detection and diagnosis, and control optimizations. …”
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Prospective assessment of learning curve and impact of intensive versus progressive training in colonoscopy competence among French residents by Léonard Wintzer-Wehekind, Lionel Moulis, Marine Camus, Geoffroy Vanbiervliet, Robert Benamouzig, Claire Duflos, Ludovic Caillo, Eric Assenat, Marc Barthet, Jean-Michel Gonzalez, Antoine Debourdeau

“…Achievement rates were similar across groups: 50% in the progressive and 65% in the intensive group (p = 0.50). …”
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Advanced 4-chamber echocardiography techniques enable clinically matched precise characterization of heart disease progression in mice by Ege Kacira, Mariam F. Oueis, Nawal H. Tamimi, Sarah L. Sturgill, Xianyao Xu, Thomas J. Hund, Mark T. Ziolo, Yuchi Han, Isabelle Deschênes, Ji-dong Fu

“…Conclusions: The A4CLAX imaging approach provides clinically comparable, comprehensive echocardiographic evaluation in murine models and offers improved sensitivity for detecting subtle changes in cardiac performance during disease progression.…”
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Development of a model for prediction of relaxation and progression of hormone-resistant form of endometrial hyperplasia in women of reproductive age by D.A. Khaskhachykh

“…The study is aimed at developing a model for predicting recurrence or progression of hormone-resistant endometrial hyperplasia in women of reproductive age. …”
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Mir-615-3p promotes osteosarcoma progression via the SESN2/AMPK/mTOR pathway by Xuecheng Yu, Xin Wang, Fan Xu, Xinyi Zhang, Muyi Wang, Ruikai Zhou, Zhengyi Sun, Xiaohui Pan, Lin Feng, Wanchao Zhang, Yong Sun, Wenting Zhang, Dong Zhou, Yuqing Jiang

“…Analysis of apoptosis was performed based on flow cytometric detection. The potential mechanisms of miR-615-3p in OS progression were investigated through RNA immunoprecipitation (RIP) assays, dual-luciferase reporter assays, qRT-PCR and western blotting. …”
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Epigenetic-modification associated hnRNPA3 acts as a prognostic biomarker and promotes malignant progression of HCC by Xufan Cai, Weihui Guo, Fang Wu, Weilang Xu, Tao Ding, Yizhe Diao, Lei Wang, Zhenyuan Qian, Guangyuan Song

“…RNA-seq showed hnRNPA3 played an important regulatory role in the malignant progression of HCC. Conclusion hnRNPA3 was found to represent a promising biomarker within HCC diagnosis and prognosis and maybe a potential drug-target in HCC therapy.…”
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Association of Alzheimer's Disease Blood Biomarkers With Sarcopenia Incidence and Progression: A 12‐Year Population‐Based Study by Chiara Ceolin, Caterina Gregorio, Alice Margherita Ornago, Giulia Grande, Martina Valletta, Caterina Trevisan, Adrián Carballo Casla, Giuseppe Sergi, Amaia Calderón‐Larrañaga, Davide Liborio Vetrano

“…Conclusions Our study, unique for its long follow‐up duration, explores the relationship between sarcopenia and neurodegeneration biomarkers, highlighting the role of p‐tau181 and NfL in the progression of the condition. These biomarkers could potentially serve as indicators for the early detection of sarcopenia, particularly in older adults and males, offering insights that may contribute to personalized screening and targeted interventions.…”
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Wb5, a novel biomarker for monitoring efficacy and success of mass drug administration programs for Wuchereria bancrofti elimination. by Rachel E Pietrow, Catherine Bjerum, Benjamin G Koudou, Taniawati Supali, Philip J Budge, Peter U Fischer, Thomas B Nutman, Sasisekhar Bennuru

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SFSCDNet: A Deep Learning Model With Spatial Flow-Based Semantic Change Detection From Bi-Temporal Satellite Images by K. S. Basavaraju, N. Sravya, Vibha Damodara Kevala, Shilpa Suresh, Shyam Lal

“…To overcome these limitations, this paper proposes a novel network called the Spatial Flow-based Semantic Change Detection Network. This network processes bi-temporal satellite images using a dual-encoder, triple-decoder architecture that progressively refines spatial features at each network stage, improving semantic change detection results. …”
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Maximum likelihood estimators are ineffective for acoustic detection of rare bat species. by Bradley H Hopp, Donald I Solick, John Chenger, Christian M Newman

“…Each program required a similar number of files to detect presence for some species, such as Myotis septentrionalis and M. sodalis (8 to 10 files), but differed in file requirements for other species, such as Lasiurus cinereus (KPro =  4; SonoBat =  7) and Perimyotis subflavus (KPro =  10; SonoBat =  6). …”
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Analysis of the breast cancer progression frequency depending on the amount of surgical treatment performed after neoadjuvant drug therapy by M. Yu. Rykov, D. A. Maksimov

“…During the three-year follow-up period, the progression of the disease after subcutaneous RME was detected in 7 (14 %) patients. …”
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Development of a General Composite Scale (GENCOMS) for Progressive Neurodegenerative Diseases and Implications for the Assessment of Disease-Modifying Therapies by Samuel P. Dickson, Craig H. Mallinckrodt, Basia Rogula, Lauren C. Powell, Michele H. Potashman, Vladimir Coric, Gilbert J. L’Italien, Suzanne B. Hendrix

“…Composite scales optimize the sensitivity for detecting clinically meaningful effects that slow disease progression. …”
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miR-486 Promotes the Invasion and Cell Cycle Progression of Ovarian Cancer Cells by Targeting CADM1 by Chenyang Li, Yue Wang, Hao Wang, Bowen Wang, Yunxia Wang, Nan Li, Yanli Qin, Yesheng Wang

“…Western blot was carried out to detect the expression of CADM1 protein and the proteins associated with cell cycle progression. …”
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Irisin suppressed the progression of TBI via modulating AMPK/MerTK/autophagy and SYK/ROS/inflammatory signaling by Kuo Zhang, Yihui Du, Sihui Yang, Guozhu Sun

“…Western blot is used to detect protein expression in both in vivo and in vitro experiments. …”
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How have Enterococcal bacteremias progressed in the last 5 years? Epidemiology, resistance to antimicrobials, risk factors, complications by Nuran Sarı, Nurefşan Tuba Kurt, Özlem Kurt Azap

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Prognostic value of circ_0000043/miR-590-5p in cervical cancer and regulation of tumor progression by Yue Zhu, Xi Shi, Shanshan Zhang, Hongyin Cui, Baohua Wu

“…Conclusion Patients with low circ_0000043 expression have poor prognosis as it fuels CC progression by boosting cancer cell proliferation, migration, and invasion via miR-590-5p. …”
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MEASUREMENT OF INTRATHORACIC IMPEDANCE IN IMPLANTED ANTIARRHYTHMIC DEVICES BY REMOTE MONITORING SYSTEM IN DIAGNOSIS OF SUBCLINICAL HEART FAILURE PROGRESSION by SERGEY E. Mamchur, MAXIM O. Petelin, EGOR A. Khomenko, TATIANA Y. Chichkova, MARIA P. Romanova, DMITRIY G. Podolyak

“…Implantation of antiarrhythmic devices is able to significantly improve both survival rates and quality of life of such patients. Currently, CHF progression can be reliably detected by a measurement of intrathoracic impedance. …”
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