Characterization of Strip1 Expression in Mouse Cochlear Hair Cells by Shasha Zhang, Ying Dong, Ruiying Qiang, Yuan Zhang, Xiaoli Zhang, Yin Chen, Pei Jiang, Xiangyu Ma, Leilei Wu, Jingru Ai, Xia Gao, Pengjun Wang, Jie Chen, Renjie Chai, Renjie Chai, Renjie Chai, Renjie Chai

“…Striatin-interacting protein 1 (Strip1) is a core component of the striatin interacting phosphatase and kinase (STRIPAK) complex, which is involved in embryogenesis and development, circadian rhythms, type 2 diabetes, and cancer progression. However, the expression and role of Strip1 in the mammalian cochlea remains unclear. …”
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Early onset development of hypertrophic cardiomyopathy in less than 1 year in a patient with familial Friedrich's ataxia: Case report by Yasmine Ouaddouh, MD, Salma Bouyaddid, MD, Zakaria Bazid, MD, PhD, Nabila Ismaili, MD, PhD, Noha El Ouafi, MD, PhD

“…Friedreich's ataxia (FRDA) is a neurodegenerative disease characterized by progressive ataxia, dysarthria, sensory loss. While neurological symptoms are prominent, cardiac manifestations significantly contribute to mortality. …”
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TRPC6 knockdown-mediated ERK1/2 inactivation alleviates podocyte injury in minimal change disease via upregulating Lon peptidase 1 by Jianwei Ma, Liling Ren, Qin Su, Xiuyi Lv, Min Sun, Yunbo Wei, Lili Dai, Xueyan Bian

“…Lon peptidase 1 (LONP1) has been suggested to protect podocytes from damage during the progression of MCD. Accordingly, our research further explored the specific mechanisms of LONP1. …”
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Autoimmune alopecia areata due to thymoma without myasthenia gravis: a case report by Yukino Saito, Tomohiro Yazawa, Toshiteru Nagashima, Yoichi Ohtaki, Natsuko Kawatani, Eiji Narusawa, Ryohei Yoshikawa, Nozomi Matsumura, Tatsuro Maehara, Ken Shirabe

“…Case presentation A 60-year-old woman had a complaint of rapid progression of alopecia areata. A hair follicular biopsy was performed, which showed the infiltration of CD8-positive lymphocytes. …”
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Integrative metabolomics and proteomics reveal the effect and mechanism of Zi Qi decoction on alleviating liver fibrosis by Xiaoying Chen, Yifan Wang, Xiaoyun Dou, Jie Wan, Jingwen Zhou, Tianci Li, Jun Yu, Fang Ye

“…Abstract Liver fibrosis is a common progressive liver disease that can cause liver dysfunction and lead to serious complications. …”
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Abnormal expression of Hippo–YAP1 signalling pathway and progesterone resistance mechanism in endometrial polyps by Xinyu Yu, Weijia Kong, Kaiyue Shang, Hongxin Xing, Wenjing Sun, Qianqian Li, Hui Zhang

“…The expression of PR in EPs tissues was significantly lower than that in normal endometrial tissues (p < .05), and the expression level of PRL was lower than that of normal endometrium in EPs tissues (p < .001).Conclusions EPs have progesterone resistance, and the Hippo–YAP1 signalling pathway may be involved in the development and progression of EPs by acting on the progesterone resistance mechanism.…”
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Kidney Disease: Improving Global Outcomes Summit Recommendations on Implementation of Diabetes Management in CKD: From Primary to Data-Driven Collaborative Care by Philip Kam-Tao Li, Michael Cheung, Kai-Ming Chow, Maria Kwan Wa Leung, Lee-Ling Lim, Juliana N.M. Lui, Andrea O.Y. Luk, Jo-Anne Manski-Nankervis, Samuel Seidu, Nikhil Tandon, Adrian Liew, Peter Lin, Fei Chau Pang, Na Tian, Kohjiro Ueki, Martin C.S. Wong, Sophia Zoungas, Kit Man Loo, Kin Lai Chung, Victor Hin-Fai Hung, Huyen Thi Thanh Vu, Maggie Lee, Junne-Ming Sung, Cheuk Chun Szeto, Man Wo Tsang, Sunny Wong, Jack Kit Chung Ng, Harriet Chung, Sydney C.W. Tang, Kenny Kung, Sing Leung Lui, David V.K. Chao, Coral Cyzewski, Tanya Green, Juliana C.N. Chan

“…Type 2 diabetes and chronic kidney disease (CKD) are preventable and treatable. Their silent and progressive clinical course calls for structured assessment with timely feedback to patients and care providers for activating decision-making. …”
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Automated gait analysis indicates efficacy of T-type calcium channel inhibition for mitigation of disrupted calcium signalling in an SCA5 mouse model by Daumante Suminaite, Nurul Fatihah Talib, Sophie Jane Pettegree, Han Chew Gaelan Tan, Yvonne Louise Odey, Emma Margaret Perkins, Alastair Robert Lyndon, Paul Andrew Skehel, Mandy Jackson

“…Abstract Spinocerebellar ataxias (SCAs) are dominantly inherited progressive neurodegenerative disorders which to date have no effective treatment. …”
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Clinical Efficacy and Safety of Ultrasound-Guided Injection with Low-Molecular-Weight Peptides from Hydrolyzed Collagen in Patients with Partial Supraspinatus Tendon Tears: A Pilot... by Luca Latini, Francesco Porta, Vincenzo Maccarrone, Davide Zompa, Edoardo Cipolletta, Riccardo Mashadi Mirza, Emilio Filippucci, Florentin Ananu Vreju

“…US-guided injections were well tolerated and, apart from one patient with a progression of a tendon tear, no adverse events were recorded. …”
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DNA damage checkpoint adaptation genes are required for division of cells harbouring eroded telomeres by Sofiane Y. Mersaoui, Serge Gravel, Victor Karpov, Raymund J. Wellinger

“…Here we show that Cdc13-independent cells grow with persistently recognized DNA damage, which does not however result in a checkpoint activation; thus no defect in cell cycle progression is detectable. The absence of checkpoint signalling rather is due to the accumulation of mutations in checkpoint genes such as RAD24 or MEC1. …”
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Characterization of Transcription Termination-Associated RNAs: New Insights into their Biogenesis, Tailing, and Expression in Primary Tumors by Ilaria Laudadio, Sara Formichetti, Silvia Gioiosa, Filippos Klironomos, Nikolaus Rajewsky, Giuseppe Macino, Claudia Carissimi, Valerio Fulci

“…AGO-bound TTSa-RNAs derive from genes involved in cell cycle progression regulation and DNA integrity checkpoints. …”
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Tracking spasticity dynamics in hemiparetic stroke survivors following cyproheptadine administration: a pilot study using controlled varying tendon indentation depths by Sungjin Bae, Sungjin Bae, Matthieu K. Chardon, Elliot J. Roth, Elliot J. Roth, William Z. Rymer, William Z. Rymer, Nina L. Suresh, Nina L. Suresh

“…In this study, we utilized the Linmot® tapper to assess the stretch reflex threshold (SRT) in three stroke survivors and one control subject by progressively altering tendon indentation to change muscle length. …”
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The Role of Epstein-Barr Virus in the Pathogenesis of Autoimmune Diseases by Natalia Morawiec, Bożena Adamczyk, Aleksandra Spyra, Mikołaj Herba, Sylwia Boczek, Natalia Korbel, Piotr Polechoński, Monika Adamczyk-Sowa

“…This review aims to establish the role of EBV in the development and progression of autoimmune diseases. <i>Materials and Methods</i>: A literature search was conducted using PubMed, PMC, Google Scholar, and SCOPUS. …”
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A fluorescence-based protocol to monitor bacterial antagonism by Justin M. Luu, Cristian V. Crisan, Morgan L. Pettis, Anayancy Ramos Facio, Timothy D. Read, Joanna B. Goldberg

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Phytochemical and Biological Investigations of Crude Extracts of <i>Astragalus pisidicus</i> by Esra Aydemir, Elif Odabaş Köse, Serap Özkaya Gül, Alaaddin Korkut, A. Cansu Kilit, Mehmet Engin Celep, Mustafa Yavuz, R. Süleyman Göktürk, Cengiz Sarikurkcu

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Blending electronic techniques with traditional teaching methods to enhance chest X-ray interpretation in medical students. by Mohsen Gholinataj Jelodar, Samaneh Mirzaei

“…This study aims to examine the impact of an electronic educational program on the ability of medical students to interpret chest radiographs.…”
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Elucidation of the Active Agents in a West African Ground Herbal Medicine Formulation That Elicit Antimalarial Activities in In Vitro and In Vivo Models by Solomon Owumi, John O. Olanlokun, Bocheng Wu, Abiola Marian Duro-Ladipo, Sophia E. Oyelere, Shabana I. Khan, Adegboyega K. Oyelere

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Development of colorimetric and fluorescent closed tube LAMP assay using simplified extraction for diagnosis of Meloidogyne enterolobii in root tissues by Arunee Suwanngam, Philipp H. Schiffer, Anongnuch Sasnarukkit, Suradej Siripattanapipong, Kansiree Jindapunnapat, Buncha Chinnasri, Toon Ruang-areerate

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IDENTIFICATION OF THE CTX-M GENE IN KLEBSIELLA PNEUMONIAE PRODUCING ESBLS IN UTI PATIENTS AT A PRIVATE HOSPITAL IN PURWOKERTO, BANYUMAS REGENCY, CENTRAL JAVA - CROSS SECTIONAL STUD... by Anang Kurniawan, Joko Setyono, Dwi Utami Anjarawati

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Allelic Imbalance in TOR1A mRNA Expression in Manifesting and Non-Manifesting Carriers of the GAG-Deletion by Ioanna A. Armata, Andreas I. Diplas, Laurie J. Ozelius, Pullanipally Shashidharan

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