The 2-Step Mendelian Randomisation Study Assesses Genetic Causality and Potential Mediators of Periodontal Disease and Atrial Fibrillation by Xiaohan Zhang, Chengzhong Lian, Shuqing Shi, Jiaran Li, Lianxin Wang, Zezhen Guo, Naixu Liu, Huan Wang, Yuanhui Hu, Bai Du

“…Conversely, no causal relationship was detected indicating that AF leads to periodontal disease condition. …”
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Complex and severe infection in a 67-year-old liver transplant recipient due to Cunninghamella elegans, Bordetella bronchiseptica, and Pneumocystis jirovecii by Muyun Wei, Kangyi Gu, Juanxiu Qin, Xinhua Lu, Junqi Feng, Shaowei Mao, Min Li, Zhilan Li, Changsheng Wang

“…B. bronchiseptica, P. jirovecii, Aspergillus fumigatus, and human alphaherpesvirus 1 (HSV1) were detected by clinical metagenomic next-generation sequencing (mNGS) of his bronchoalveolar lavage fluid (BLAF). …”
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Metabolomic analysis of the intrinsic resistance mechanisms of Microtus fortis against Schistosoma japonicum infection by Tianqiong He, Du Zhang, Yixin Wen, Qian Liu, Junkang Zhou, Wenling Zhi, Lingxuan OuYang, Yushan Qi, Zikang Zhou, Xin Gao, Fan Li, Zhijie Su, Jia Shen, Zhijun Zhou

“…Nevertheless, the underlying resistance mechanism of M. fortis against schistosomes are still unclear. In this study, we detected and compared colon aqueous extracts and serum metabolic profiles between M. fortis and ICR mice before and after S. japonicum infection using liquid chromatography–mass spectrometry (LC–MS). …”
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Interactions with and activation of immune cells by CD41a+ extracellular vesicles by Marie Tamagne, Marie Tamagne, Mehdi Khelfa, Mehdi Khelfa, Souganya Many, Deborah Neyrinck-Leglantier, Deborah Neyrinck-Leglantier, Adèle Silane Delorme, Adèle Silane Delorme, Marion Klea Pinheiro, Marion Klea Pinheiro, Muriel Andrieu, Sabine Cleophax, France Pirenne, France Pirenne, Benoît Vingert, Benoît Vingert

“…Given the potential involvement of monocytes in leukemia progression, we performed a new original multi-omics study to confirm the protein changes and gene activation observed following interaction with CD41a+ EVsResultsThe CD41a+ EVs had immunomodulatory effects on all these cell types but this effect depended on the numbers of EVs. …”
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Ultrasound diagnostics of traumatic pancreatitis at combined trauma by O. A. Alekseyechkina, E. Ya. Dubrov, D. A. Kosolapov, V. M. Abuchina

“…To estimate state of the pancreas in patients with combined trauma, to detect signs of traumatic pancreatitis.Material and methods. …”
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Hydrogeochemical signatures, quality and driving forces of phreatic groundwater in a typical headwater region of the Yellow River watershed by Kui Liu, Huijun Yan, Wanping Wang, Shengbin Wang, Zhigang Wang, Yong Xiao, Bo Guo, Jie Wang, Shilong Zhang, Guoqiang Zhang, Shaokang Yang, Yu Liu

“…Agricultural practices and municipal sewage contribute nitrogen and chemical constituents into phreatic aquifers, resulting in increased salinity and the progressive deterioration of phreatic groundwater quality. …”
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Pterygium Pathology: A Prospective Case-Control Study on Tear Film Cytokine Levels by Sara I. Van Acker, Michel Haagdorens, Ella Roelant, Jos Rozema, Tine Possemiers, Veerle Van Gerwen, Marie-José Tassignon, Veva De Groot, Sorcha Ní Dhubhghaill, Carina Koppen, Nadia Zakaria

“…As the composition of the tear film provides a reflection into the pathological changes at the ocular surface, tear analysis represents an ideal approach to gain insight in the progression of disease following pterygiectomy. This study enrolled 19 patients and age/gender-matched healthy controls. …”
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RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway by Qian Sun, Junjie Xu, Fan’en Yuan, Yan Liu, Qianxue Chen, Lirui Guo, Huimin Dong, Baohui Liu

“…The overexpression of RND1 suppressed the progression and migration of U87 and U251 cells. RND1 knockdown facilitated the growth and invasion of GBM cells. …”
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Primary vaginal leiomyosarcoma: A case report emphasizing multidisciplinary care of a rare entity by Fadoua Jebrouni, Hanan Bailal, Mouhsine Omari, Kaouthar Khater, Asmae Bali, Ouissam Al Jarroudi, Sami Aziz Brahmi, Said Afqir

“…Following the multidisciplinary team meeting discussion, the patient received first-line doxorubicin-based chemotherapy. Due to the progression of the disease in the lungs, the patient received second- line ifosfamide-based treatment, with an excellent tolerance. …”
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Unveiling the complex extra‐oral colonization pathways and pathogenic mechanisms of Fusobacterium nucleatum, a heterogeneous oral pathogen by Zhiwei Guan, Houbao Qi, Qiang Feng

“…It is not only an opportunistic pathogen of periodontitis but also can be frequently detected at the lesion sites of various systemic diseases. …”
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Effect of conditioned medium from miRNA-34a transfected gastric cancer-associated fibroblast on peripheral blood mononuclear cells by Mozhgan Esmaili, Narjes Jafari, Fatemeh Ahmadzadeh, Seyed Mohammad Valizadeh Toosi, Saeid Abediankenari

“…MiRNA dysregulation has been detected in CAF cells, which is related to the tumor progression ability of these cells. …”
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Identification of non-invasive biomarkers associated with glioma hemorrhage by Ozal Beylerli, Leili Gulieva, Valentin Pavlov, Huaizhang Shi

“…Hemorrhage within gliomas, although relatively uncommon, can exacerbate disease progression, complicate clinical decision-making, and worsen patient outcomes. …”
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Assembly technology and design features of microelectronic coordinate-sensitive detectors by V. P. Sidorenko, V. D. Zhora, O. I. Radkevich, V. P. Grunyanska, Yu. V. Prokofiev, Yu. V. Tayakin, Т. М. Virozub

“…The device is based on the specialized very-large-scale integration (VLSI) crystal manufactured using CMOS technology and containing a charge-sensitive matrix designed to detect isotope ions in a wide mass spectrum of the test substance. …”
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Role of T cell exhaustion and tissue-resident memory T cells in the expression and prognosis of colorectal cancer by Han Wu, Pei-Wen Fan, Ya-Ning Feng, Cheng Chang, Ting Gui, Jia-bei Meng, Ruo-Zheng Wang

“…Abstract The tumour microenvironment (TME) is complex and dynamic, and changes significantly with tumour progression. Studying the evolving state of T cells, especially tumour-specific subsets, has become feasible. …”
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Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3′ untranslated region in MCF7 cells by Xin Yan, Qianyin Li, Dongsheng Ni, Yajun Xie, Qingling He, Qianya Wan, Yamin Liu, Zhongshi Lyu, Zhaomin Mao, Qin Zhou

“…However, few study reported its role in progression of breast carcinoma cells. Wound healing assay and flow cytometry were applied to detect the migration and apoptosis; western blot, real-time polymerase chain reaction, and dual-luciferase assays were applied to investigate the potential regulation mechanism of A1CF-mediated cell migration and apoptosis. …”
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A novel anti-mouse CXCR1 monoclonal antibody, Cx1Mab-8, demonstrates nanomolar affinity in flow cytometry by Guanjie Li, Hiroyuki Suzuki, Tomohiro Tanaka, Hiroyuki Satofuka, Mika K. Kaneko, Yukinari Kato

“…The IL-8-CXCR1 axis also plays an important role in tumor progression, especially in the tumor microenvironment. …”
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Processing Factors and Risk Assessment of Pesticide Residues in Wine by Sandra Cermeño, José Manuel Veiga-del-Baño, Miguel Ángel Cámara, Pedro Andreo-Martínez, José Oliva

“…Penconazole, kresoxim-methyl and trifloxystrobin were not detected at the beginning of the vinification stage. …”
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The Proresolving Lipid Mediator Maresin1 Alleviates Experimental Pancreatitis via Switching Macrophage Polarization by Yingying Lu, Guotao Lu, Lin Gao, Qingtian Zhu, Jing Xue, Jingzhu Zhang, Xiaojie Ma, Nan Ma, Qi Yang, Jie Dong, Weijuan Gong, Weiqin Li, Zhihui Tong

“…This study also demonstrated that MaR1 could alleviate fibrosis to limit AP progression in the CP model. Conclusion. Our data suggests that MaR1 was a therapeutic and preventive target for AP in mice, likely operating through its effects on decreased macrophage infiltration and phenotype switch.…”
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Effect of chitosan on buck semen quality and semen plasma metabolites during low-temperature storage by Meijun Song, Meijun Song, Bingke Jia, Bingke Jia, Dinghui Dai, Dinghui Dai, Xiaoli Xu, Xiaoli Xu, Jiaxue Cao, Jiaxue Cao, Jiazhong Guo, Jiazhong Guo, Linjie Wang, Linjie Wang, Tao Zhong, Tao Zhong, Siyuan Zhan, Siyuan Zhan, Li Li, Li Li, Hongping Zhang, Hongping Zhang

“…A total of 23 classes of metabolites were detected in the non-targeted metabolism group of seminal plasma. …”
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The Oral Microbiome in Queensland Free-Ranging Koalas (<i>Phascolarctos cinereus</i>) and Its Association with Age and Periodontal Disease by Lyndall Pettett, Esmaeil Ebrahimie, Teerapol Chinkangsadarn, Manijeh Mohammadi Dehcheshmeh, Darren J. Trott, Philip S. Bird

“…Findings may contribute to better understanding of oral disease progression in koalas and support conservation and health management efforts.…”
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