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Suggested Topics within your search.
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10921
Dynamics and consequences of the HTLV-1 proviral plus-strand burst.
Published 2022-11-01“…Tax expression was associated with a transient slowing in cell-cycle progression and proliferation, increased apoptosis, and enhanced activation of the DNA damage response pathways. …”
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10922
Morphometric evaluation of the astrocytes reactivity in preterm and term infants with infectious diseases
Published 2014-12-01“…Whereas due to maturation of astrocytes in children born after 34 weeks of gestation more common moderate and severe stages of astrocytes reactivity (collectively, 69,6%) was detected. Severe stage of the reactive astrocytes accompanied by the development of necrotic lesions in the periventricular white matter in 64,3% of cases, in our opinion, as a result of progressive degenerative process in glial cells. …”
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10923
Nucleolar sequestration of cannabinoid type-2 receptors in triple-negative breast cancer cells.
Published 2025-01-01“…The cannabinoid type-2 receptor (CB2R) has been proposed as a central player in tumor progression and has been correlated with the aggressiveness of breast cancer. …”
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10924
PRDX1 knockdown promotes erastin-induced ferroptosis and impedes diffuse large B-cell lymphoma development by inhibiting the MAPK/ERK pathway
Published 2025-04-01“…Methods The expression of PRDX1 in DLBCL tissues and cells was detected using bioinformatics analysis and reverse transcription quantitative PCR. …”
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10925
Assessing the carcinogenic potential and molecular mechanisms of arecoline in human lungs: from in silico methods to in vitro validation
Published 2025-04-01“…These target proteins influence the occurrence, progression, and immune infiltration of LUAD by participating in pathways related to cancer and immunity, thereby affecting the prognosis and immunotherapy of LUAD patients. …”
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10926
The correlation between the monocyte to HDL ratio and diabetic kidney disease
Published 2019-01-01“…Conclusions MHR can be used as a risk factor for progression of DKD. Clinically, the patient whose MHR is over 0.396 needs further related examinations. …”
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10927
Exogenous H2S reduces oxidative stress induced by lipid mixture in HepG2 cells through USP22/SIRT1 axis
Published 2025-07-01“…Oxidative stress is an important mechanism that causes the pathological progression of NAFLD. However, the effect and specific mechanism of exogenous H2S on oxidative stress in NAFLD are still unclear. …”
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10928
P300 Latency with Memory Performance: A Promising Biomarker for Preclinical Stages of Alzheimer’s Disease
Published 2024-12-01“…Detecting and tracking the preclinical stages of Alzheimer’s disease (AD) is now of particular interest due to the aging of the world’s population. …”
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10929
Loss of Cellular Sialidases Does Not Affect the Sialylation Status of the Prion Protein but Increases the Amounts of Its Proteolytic Fragment C1.
Published 2015-01-01“…Recent studies revealed a correlation between the sialylation status of PrPSc and incubation time to disease and introduced a new hypothesis that progression of prion diseases could be controlled or reversed by altering the sialylation level of PrPC. …”
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10930
Development of an acute and highly pathogenic nonhuman primate model of Nipah virus infection.
Published 2010-05-01“…Exposure of eight monkeys to NiV produced a severe systemic infection in all eight animals with seven of the animals succumbing to infection. Viral RNA was detected in the plasma of challenged animals and occurred in two of three subjects as a peak between days 7 and 21, providing the first clear demonstration of plasma-associated viremia in NiV experimentally infected animals and suggested a progressive infection that seeded multiple organs simultaneously from the initial site of virus replication. …”
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10931
Neuronal Deletion of <i>Tumor Susceptibility Gene 101</i> (<i>Tsg101</i>) Causes Rapid Apoptotic Loss of Hippocampal CA3 Neurons
Published 2025-05-01“…Failure to detect lipidated LC3 indicated autophagy was impaired rather than upregulated. …”
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10932
Mesenchymal Stem Cells Accelerate Recovery of Acetic Acid-Induced Chronic Gastric Ulcer by Regulating Ekt/Akt/TRIM29 Axis
Published 2024-01-01“…In addition, we could detect the homing of MSCs in gastric tissue, and MSCs may differentiate into Lgr5-positive cells. …”
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10933
Adult-onset Still's disease: Clinical cases
Published 2014-12-01“…In the majority of patients, articular involvement progresses and destructive polyarthritis develops. Symmetric involvement of the carpophalangeal and distal interphalangeal joints is frequently detected. …”
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10934
A multi-centre study on the role of the thioredoxin system in breast cancer cell proliferation
Published 2018-12-01“…The study of the molecular mechanisms of the onset, development and progression of malignant neoplasms underlies the search for tumor-associated markers and potential targets for personalized antitumor therapy.Purpose. …”
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10935
Clinical and functional state of the retina after inadequate laser coagulation of peripheral vitreochorioretinal dystrophies. Part 1. Electroretinography
Published 2020-05-01“…Ganzfeld ERG and multifocal ERG (mfERG) were recorded in 18 patients (32 eyes) with PVСRD in which, upon examination of the fundus, signs of inadequate retinal LC were detected and documented, such as hypercoagulation, an excessively large number of coagulates with minimal changes in the retina, or massive LC at the normal fundus. …”
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10936
SNHG19 promotes the proliferation and metastasis of hepatocellular carcinoma through regulating the miR-137/protein tyrosine phosphatase 4A3 axis
Published 2025-04-01“…Methods: The expression of SNHG19 in hepatocellular carcinoma tissues were detected by using quantitative Real-Time Reverse Transcription Polymerase Chain Reaction (qRT-PCR). …”
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10937
Soluble receptor for advanced glycation end products and its role in cardiovascular risk assessment in hyperglycemia – A study in North India
Published 2025-04-01“…Introduction: Advanced glycation end products (AGEs) and their cellular receptors (RAGEs) play an important role in the pathogenesis of type 2 diabetes mellitus and its progression to cardiovascular disease (CVD). A marker of the AGE-RAGE axis, soluble RAGE (sRAGE), was examined in this study in various glycemic states as well as in low- and high-CVD-risk patients. …”
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10938
Analysis of the Retinal Nerve Fiber Layer in Retinitis Pigmentosa Using Optic Coherence Tomography
Published 2015-01-01“…Sd-OCT is highly sensitive and effective instrument to detect RNFL changes in RP patients. RNFL measurements can provide information about the progression of retinitis pigmentosa and may provide prognostic indices for future treatment modalities.…”
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10939
Xanthine oxidase inhibitors in asymptomatic hyperuricemia
Published 2019-10-01“…The worldwide prevalence rate of AHU has been on the increase in recent decades: it has been detected in approximately every five inhabitants of the Earth. …”
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10940
The Globular Cluster System of the Virgo Cluster Ultradiffuse Galaxy VCC 615
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