Peptide vaccine targeting mutated GNAS: a potential novel treatment for pseudomyxoma peritonei by Ben Davidson, Kjersti Flatmark, Annette Torgunrud, Karianne G Fleten, Hedvig V Juul, Nadia Mensali, Christin Lund-Andersen, Else Marit Inderberg

“…Fresh PMP tumor samples were analyzed by mass cytometry using a panel of 35 extracellular markers, and cellular subpopulations were clustered and visualized using the visual stochastic network embedding analysis tool.Results GNAS mutations were detected in 22/25 tumor samples (88%; R201H and R201C mutations detected in 16 and 6 cases, respectively). …”
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Evaluation of Beta Globin Gene Mutations in Beta Thalassemia Carrier Children in Aydın Province and its Environment by Deniz Ilgün, Yusuf Ziya Aral, Mediha Akcan, Özgür Cartı, Gökay Bozkurt

“…Seventeen different mutations were detected. The mutations most frequently occurred in “intron 1” gene region (66.1%). …”
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Storage damage of cold-stored whole blood in CPDA maintenance fluid during the whole effective storage period by Yingyu He, Yiquan Zhang, Wanbing Liu, Lidong Zhang, Yingkai Xu, Zihan Yuan, Junying Li, Lei Liu, Fangxiong Cheng

“…By the day 28 of storage, coagulation activity decreased alongside elevated hemolysis markers, indicating progressive and remarkable storage lesion development. …”
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ARID1A deficiency attenuates the response to EGFR-TKI treatment in lung adenocarcinoma by Fangfang Yang, Fangfang Yang, Helei Hou, Guanqun Wang, Guangming Fu, Xingfa Huo, Xueqin Duan, Na Zhou, Xiaochun Zhang

“…By analysing the clinical data of our centre, we revealed that patients with loss of ARID1A expression demonstrated poorer median progression-free survival (mPFS, 10.3 versus 30 months, P = 0.005) when they received EGFR-TKIs as the first-line treatment after postoperative progression (cohort A). …”
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Predictive value of MMP-2, MMP-9, TIMP-1 in surgical treatment of localized renal cell cancer by A. I. Tarasenko, A. N. Rossolovskiy, O. L. Berezinets, D. A. Durnov, E. B. Popyhova, V. M. Popkov

“…The highest sensitivity and specificity for detecting tumor progression was demonstrated by matrix metalloproteinases: MMP‑2 – sensitivity 96 %, specificity 67 % (cut-off point 357.5 pg/ml) and MMP‑9 – sensitivity 87.5 % and specificity 62 % (cut-off point 958 ng/ml). …”
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Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro by Yong-Jia Song, Jia-Min Bao, Zeng-Qiao Zhang, Yun-Xiang Hai, Hao-Nan Wen, Tian-Jun Zhai, Wei Feng, Min Song

“…Objective: Osteoarthritis (OA) is a progressive joint disease characterized by degeneration and destruction of articular cartilage. …”
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MYO1G promoter hypomethylation correlates with its mRNA expression, lymphocyte infiltration, and immunotherapy response in melanoma by Yonghua Xia, Yushu Zhang, Chenxi Zheng, Junbo Wang, Wenyu Di, Mengjie Zhang, Minglei Yang

“…In our cohort, patients with MYO1G promoter hypomethylation showed significantly elevated tumor-infiltrating lymphocytes level and prolonged progression-free survival after immunotherapy.ConclusionOur study highlights MYO1G promoter methylation as a key regulator of gene expression and a potential prognostic and predictive biomarker for immunotherapy response in melanoma. …”
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Insights into the blood, gut, and oral microbiomes in Chinese patients with myocardial infarction: a case-control study by Ikram Khan, Imran Khan, Ping Xie, Yu Xiaohui, Shengnan Lei, Tianzhu Song, Zhiqiang Li, Xiaodong Xie

“…The unique microbial patterns detected in the blood provide compelling evidence for the existence of a stable core blood microbiome, highlighting its importance as a key contributor to cardiovascular health and disease progression.…”
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Anatomic and Topographic Vitreous and Vitreoretinal Interface Features in Proliferative Diabetic Vitreoretinopathy by N. M. Kislitsyna, S. V. Novikov, S. V. Kolesnik, A. I. Kolesnik, M. P. Veselkova

“…In PDR patients, the VMI changes can significantly influence the emergence and progression of the disease. There are multiple factors at work in the VMI including taut posterior cortical layers, vitreoschisis, posterior vitreous detachment (PVD), and vitreous adhesions. …”
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The prognostic value of systemic inflammation response index in digestive system carcinomas: a systematic review and meta-analysis by Zuo-hu Niu, Li Lin, Hong-ye Peng, Xin-zhuo Zheng, Mi-yuan Wang, Feng-xia Sun, Chun-jun Xu

“…The primary outcome of interest was the overall survival (OS), while secondary outcomes included progression-free survival (PFS), disease-free survival (DFS), time to progression (TTP), and disease specific survival (DSS). …”
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Acupotomy Ameliorates KOA Related Chondrocyte Premature Senescence Through YAP/FOXD1 Pathway by Ma Y, Hu T, Liu N, Guo C, Xing L, Ma W, Cui Y, Chen X

“…Cartilage degeneration was detected by safranin O-fast green staining and transmission electron microscope(TEM). …”
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Early Diagnosis of Knee Osteoarthritis With a Natural Language Processing–Driven Approach Based on Clinician Notes: Development and Validation Study by Narathip Thanyakunsajja, Kulsawasd Jitkajornwanich, Shan Xu, Donghee Shin, Pattama Charoenporn

“…Although this disease is chronic and irreversible, the patient’s condition can be improved and the progression of the disease can be prevented if the disease is diagnosed early and the patient receives appropriate treatment immediately. …”
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Cardiorenal interactions in patients with juvenile idiopathic arthritis by L. F. Bohmat, N. S. Shevchenko, T. O. Holovko, V. V. Nikonova

“…In children with juvenile idiopathic arthritis (JIA), decreased adaptability of the cardiovascular system is detected in 17.0–20.0 % of cases. 36.9 % of children with JIA develop renal lesions. …”
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NCBP2 predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis by Shichao Li, Yulan Wang, Xi Yang, Miao Li, Guoxiang Li, Qiangqiang Song, Junyu Liu

“…NCBP2 was correlated with overall survival (OS), disease-specific survival (DSS), and progression-free survival (PFS) in various cancers. …”
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Global consumption of protein and calories: Interrelation with the diet and products for elimination of deficiency by A. A. Stepanova, L. K. Asyakina

“…Analysis of the data array containing information about 100 healthiest foods taken from Kaggle and processed in the program Power BI was able to reveal products that are most rich in protein, dietary fiber and vitamin C, as well as to detect the antioxidant index of products, their caloric content and geographical origin. …”
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Relationship between “self-efficiency“ competence levels and constant sportive self-respect levels of football players (Sample of Istanbul European Side) by Aydın Pekel, Kubilay Çimen

“…The obtained data was recorded with the package program named "IBM SPSS 22". Correlation analysis and regression analysis were applied as statistical procedure. …”
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IoT-based home control system using NodeMCU and Firebase by Paul Oluwatobiloba Ayeni, Olayiwola Charles Adesoba

“…The user interacts with the IoT system through a mobile application named My Home, developed using Java programming language, and this mobile application is also interfaced with the Firebase cloud server. …”
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Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis. by Katy Poncin, Samantha A McKeand, Hayley Lavender, Kacper Kurzyp, Odile B Harrison, Annabell Roberti, Charlotte Melia, Errin Johnson, Martin C J Maiden, David R Greaves, Rachel Exley, Christoph M Tang

“…Autolysis is a form of programmed cell death (PCD) which is part of the life cycle of remarkably few bacteria and poses an evolutionary conundrum as altruistic death provides no obvious benefit for single-celled organisms. …”
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A SYSTEMATIC REVIEW: MOBILE APPLICATION MONITORING POST OPERATION CAESAREAN SECTION by zahrotul - widad, Ninuk Dian Kurniawati, Kristiawati Kristiawati

“…In assessing research bias using the Critical Appraisal Skills Program (CASP) and the Joanna Briggs Institute (JBI) obtained a score of 77-100%. …”
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Decentralized finance: a comparative bibliometric analysis in the Scopus and WoS databases by Gülcihan Aydaner, H. Aydın Okuyan

“…Additionally, it was detected that the most cited countries in both databases were the USA, China and England, respectively. …”
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