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    Autoimmune Encephalitis and Paraneoplastic Neurological Syndromes with Progressive Supranuclear Palsy-like Manifestations by Naoki Yamahara, Akira Takekoshi, Akio Kimura, Takayoshi Shimohata

    Published 2024-10-01
    “…Background: Advances in diagnostic procedures have led to an increasing rate of diagnosis of autoimmune encephalitis or paraneoplastic neurological syndrome (AE/PNS) among patients with progressive supranuclear palsy (PSP)-like manifestations. …”
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    Research Progress of Liquid Biopsy Based on DNA Methylation in Tumor Diagnosis and Treatment by Yunxia Bao, Xianzhao Wang, Bingjie Zeng, Yichun Shi, Yiman Huang, Yiwen Huang, Shuang Shang, Liang Shan, Lifang Ma

    Published 2024-12-01
    “…DNA methylation, which is a type of epigenetic modification, is essential in the progression of tumors. This review introduces the common DNA methylation analysis methods and discusses their advantages and disadvantages, focusing on the new progress of DNA methylation-based liquid biopsy in tumor diagnosis and treatment.…”
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    The role of RNA methylation in glioma progression: mechanisms, diagnostic implications, and therapeutic value by Shao-Ze Zhang, Shao-Ze Zhang, Shao-Ze Zhang, Shao-Yan Liu, Meng-Die Cheng, Yin-Feng Zhang, Jia-Wei Tian

    Published 2025-05-01
    “…Glioma represents a highly lethal form of malignant tumour, with RNA methylation emerging as a critical regulator of its oncogenesis and progression. As a prevalent post-translational modification, methylation influences various biological functions, particularly RNA processing, by modulating splicing, transport, and degradation of both mRNAs and noncoding RNAs. …”
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    Large language model trained on clinical oncology data predicts cancer progression by Menglei Zhu, Hui Lin, Jue Jiang, Abbas J. Jinia, Justin Jee, Karl Pichotta, Michele Waters, Doori Rose, Nikolaus Schultz, Sulov Chalise, Lohit Valleru, Olivier Morin, Jean Moran, Joseph O. Deasy, Shirin Pilai, Chelsea Nichols, Gregory Riely, Lior Z. Braunstein, Anyi Li

    Published 2025-07-01
    “…On UCSF data, it achieved an overall AUROC of 0.88, excelling in lung cancer detection with an AUROC of 0.95. As the first oncology specific LLM validated across institutions, Woollie demonstrates high accuracy and consistency across cancer types, underscoring its potential to enhance cancer progression analysis.…”
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    Recent Progress in Intrinsically Stretchable Sensors Based on Organic Field-Effect Transistors by Mingxin Zhang, Mengfan Zhou, Jing Sun, Yanhong Tong, Xiaoli Zhao, Qingxin Tang, Yichun Liu

    Published 2025-02-01
    “…Intrinsically stretchable sensors have been widely applied in smart wearables, electronic skin, biological detection, and environmental protection. In this review, we summarize the recent progress in intrinsically stretchable sensors based on OFETs, including advancements in functional layer materials, sensing mechanisms, and applications such as gas sensors, strain sensors, stress sensors, proximity sensors, and temperature sensors. …”
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    Optical Coherence Tomography as a Biomarker for Diagnosis, Progression, and Prognosis of Neurodegenerative Diseases by Maria Satue, Javier Obis, Maria J. Rodrigo, Sofia Otin, Maria I. Fuertes, Elisa Vilades, Hector Gracia, Jose R. Ara, Raquel Alarcia, Vicente Polo, Jose M. Larrosa, Luis E. Pablo, Elena Garcia-Martin

    Published 2016-01-01
    “…Retinal thinning has been observed in these patients and new segmentation software for the analysis of the different retinal layers may provide accurate information on disease progression and prognosis. In this review we analyze the application of retinal evaluation using OCT technology to provide better understanding of the possible role of the retinal layers thickness as biomarker for the detection of these neurodegenerative pathologies. …”
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    The role of neuroimaging in Alzheimer’s disease: implications for the diagnosis, monitoring disease progression, and treatment by Julius Mulumba, Rui Duan, Bo Luo, Jiang Wu, Muhammad Sulaiman, Feng Wang, Yong Yang

    Published 2025-02-01
    “…Neuroimaging enables the visualization of Alzheimer-related biomarkers, such as Aβ plaques, tau protein tangles, neuro-inflammation, and synaptic dysfunction, providing valuable insights into disease pathophysiology and progression. These imaging techniques assist in the early detection of AD, distinguishing it from other conditions and evaluating the effectiveness of treatments. …”
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    Recent progress in tuberculosis diagnosis: insights into blood-based biomarkers and emerging technologies by Zewei Yang, Jingjing Li, Jiawen Shen, Huiru Cao, Yuhan Wang, Sensen Hu, Yulu Du, Yange Wang, Zhongyi Yan, Longxiang Xie, Qiming Li, Salwa E. Gomaa, Salwa E. Gomaa, Shejuan Liu, Shejuan Liu, Xianghui Li, Jicheng Li, Jicheng Li

    Published 2025-05-01
    “…Recent advancements in the field of TB diagnostics have focused on the identification and utilization of blood-based biomarkers, offering a non-invasive, rapid, and scalable approach to disease detection. This review provides a comprehensive overview of the latest progress in blood-based biomarkers for TB, highlighting their potential to revolutionize diagnostic strategies. …”
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