Experience in the use of olaparib poly (ADP-ribose) polymerase inhibitors in maintenance therapy of BRCA-associated ovarian cancer by V. N. Zhurman, V. M. Nechushkina

“…Mutations in the BRCA1/2 genes were detected in 98 out of 355 (27.6 %) patients. Mutations of the BRCA1+ gene were detected in 62 out of 230 patients with ovarian cancer of stages IIIC–IV (27.0 %), the BRCA2 gene – in 9 out of 230 (3.9 %). …”
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The correlation between the level of 25-hydroxyvitamin D [25(OH)D] and residency of multiple sclerosis patients in Montenegro – higher levels only in men in the north of the countr... by Vujisić Slavica, Vodopić Sanja, Idrizović Zilha, Radulović Ljiljana

“…Serum levels of 25(OH)D were associated with disability and progression in MS patients. Lower levels of 25(OH)D were detected in female patients from the North. …”
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Navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions – case report by I. S. Bakulin, A. V. Chervyakov, M. N. Zakharova, N. A. Suponeva, M. A. Piradov

“…Absence of the pyramidal syndrome does not allow diagnosing ALS, and the diagnosis of progressive muscular atrophy should be set in these cases. …”
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LC–MS/MS quantification of 20(S)-protopanaxadiol in complex biological matrices for bioanalytical method validation and pharmacokinetic analysis by Pengfei Li, Shanshan Liu, Hongyan Zhuang, Mengxi niu, Fei Pan, Nan Wang, Sha Sha, Qian Wang, Jing Wang

“…The aim of this study is to establish and validate a quantitative detection method for PPD in multiple matrices using mass spectrometry. …”
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Combined treatment of high and very high risk prostate cancer: results of neoadjuvant treatment by A. V. Troyanov, V. A. Biryukov, I. V. Zaborsky, V. S. Chaykov, I. O. Dementev, E. O. Shchukina, O. B. Karyakin

“…Combined hormone chemo‑ radiation treatment of 33 patients with prostate cancer of high and very high risk of progression without distant metastases was performed. …”
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Impact of circulating lymphoma cells at diagnosis on outcomes in patients with newly diagnosed de novo diffuse large B-cell lymphoma by Sayan Mullick Chowdhury, Subodh Bhatta, Timothy J. Voorhees, Kaitlin Annunzio, David A. Bond, Yazeed Sawalha, Audrey Sigmund, Walter Hanel, Lalit Sehgal, Lapo Alinari, Robert Baiocchi, Kami Maddocks, Beth Christian, Dan Jones, Narendranath Epperla

“…The primary endpoint was progression-free survival (PFS), and secondary endpoints included overall survival (OS) and diagnosis-to-treatment interval (DTI). …”
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IBERBIRDS: A dataset of flying bird species present in the Iberian PeninsulaZenodo by Paula Rodríguez, Rubén Parte, Guillermo A. González, Alejandra Gacho, Darío Santos, Rubén Usamentiaga, Oscar D. Pedrayes

“…To address this gap, this article introduces IBERBIRDS—a comprehensive and publicly accessible dataset specifically designed to facilitate automatic detection and classification of flying bird species in the Iberian Peninsula under real-world conditions.The dataset comprises 4000 images representing 10 ecologically significant medium to large-sized bird species, with each image annotated using bounding box coordinates in the YOLO detection format. …”
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A cost minimization analysis of the implementation of the international lung screening trial in Catalonia (Spain) by Antoni Rosell, Sonia Baeza, Rocío Mouriño, Maria Saigí, Marta Munné, Pedro López de Castro, Jordi Bechini, Oriol Estrada, Jordi Ara, Laura Ricou, Francesc López-Seguí

“…In 5-year of lung cancer screening program, the average expected costs per subject were €1,342 (range €1,054 − 1,832) for screening and €32,431 for treatment, with an expected reduction of €952 based on an average cancer detection rate of 1.6%. …”
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A SINGLE – CENTER STUDY ON THE INCIDENCE OF PCR–DETECTED INFLUENZA A/B RNA IN PATIENTS WITH SEVERE ACUTE RESPIRATORY DISEASE (2015-2019) by Matsas O.Y., Vorobiova O.V., Mulkina O.I., Slobodianiuk O.M.

“…In contrast, influenza B virus RNA was not detected during the 2015–2016, 2016–2017, and 2018–2019 seasons. …”
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Early Detection of Type 1 Diabetes in First-Degree Relatives in Saudi Arabia (VISION-T1D): Protocol for a Pilot Implementation Study by Iman S Algadi, Yazed AlRuthia, Muhammad H Mujammami, Khaled Hani Aburisheh, Metib Alotaibi, Sharifah Al Issa, Amal A Al-Saif, David Seftel, Cheng-Ting Tsai, Reem A Al Khalifah

“…Despite the potential benefits of early detection through screening programs, such initiatives are currently lacking in Saudi Arabia and other Arab countries. …”
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Radiomic-enhanced multimodal ultrasound for early detection of acute kidney injury secondary to renal vein thrombosis: a preclinical diagnostic modeling study by Ziyi Xu, Xinghua Wang, Nan Qiao, Tao Zhang

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Optimization of early diagnosis of ovarian cancer using an original software ScOv by S. V. Khabarov, S. O. Nikogosyan, V. G. Volkov, G. M. Chibisova

“…The most common causes of treatment failure in ovarian cancer (ОС) include late diagnosis due to the absence of screening programs for its early detection and lack of vigilance by general practitioners and gynecologists. …”
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A Directional Wave Spectrum Inversion Algorithm with HF Surface Wave Radar Network by Fuqi Mo, Xiongbin Wu, Xiaoyan Li, Liang Yu, Heng Zhou

“…Therefore, a quadratic programming algorithm based on the regularization technique is proposed with an empirical criterion for estimating the optimal regularization parameter, which minimizes the effect of noise to obtain more accurate inversion results. …”
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Spatio-temporal crime pattern analysis in Addis Ketema, Addis Ababa, Ethiopia: GIS and R based approaches by Ziyen Achamyeleh Mekonnen, Esubalew Mulugeta Engda, Kanenus Fufa Deraro, Natnael Agegnehu, Talema Moged Reda, Muralitharan Jothimani

“…This study presents a comprehensive approach to spatio-temporal crime analysis using R programming language. The study begins by collecting and preprocessing 5-year crime data, incorporating both spatial and temporal dimensions. …”
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Do cancer survivors have an increased risk of developing subsequent cancer? A population-based study by Yubo Wang, Yining Jiang, Yang Bai, Haiyang Xu

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Resisting the Final Line: Phenotypic Detection of Resistance to Last-Resort Antimicrobials in Gram-Negative Bacteria Isolated from Wild Birds in Northern Italy by Maria Cristina Rapi, Joel Filipe, Laura Filippone Pavesi, Stefano Raimondi, Maria Filippa Addis, Maria Pia Franciosini, Guido Grilli

“…Notably, a phenotype compatible with Extended-Spectrum Beta-Lactamase (ESBL) production was detected in four out of ten (40%) <i>K. pneumoniae</i> isolates. …”
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CD20, CTLA4, CXCL9, IL18RAP, IL-6, SOCS2, and TNF as potential biomarkers for rheumatoid arthritis disease progression: Systematic review of RNA-seq studies by Jairo Javier Jattin Balcázar, Daniel Felipe Galeano Sánchez, Gerardo Quintana López

“…DEGs were determined to be at least 38125, but 255 and 124 up- and down-regulated DEGs were detected after filtering by the top 5. Most biomarkers described were related to disease progression (61 %), while the most common analysis and tissue studied were principal component analysis (52 %) and blood (39 %), respectively. …”
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Fabrications, Applications and Challenges of Solid-state Nanopores: A Mini Review by Zifan Tang, Daihua Zhang, Weiwei Cui, Hao Zhang, Wei Pang, Xuexin Duan

“…In addition, molecular translocation developments, DNA sequencing and protein detections are summarized. Finally, the latest progress relating to solid-state nanopores is discussed, which helps to offer a comprehensive under‐ standing of the current situation for solid-state nanopore sensors.…”
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Unmasking social bots: how confident are we? by James Giroux, Gangani Ariyarathne, Alexander C. Nwala, Cristiano Fanelli

“…Abstract Social bots remain a major vector for spreading disinformation on social media and a menace to the public. Despite the progress made in developing multiple sophisticated social bot detection algorithms and tools, bot detection remains a challenging, unsolved problem that is fraught with uncertainty due to the heterogeneity of bot behaviors, training data, and detection algorithms. …”
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A comparison of urban and rural populations among gay, bisexual, and other men who have sex with men and transgender woman using an online HIV self-sampling program in Spain (2018–... by Héctor Martínez-Riveros, Miquel Saña, Victoria González, Marcos Montoro-Fernandez, Yesika Díaz, Esteve Muntada, Pol Romano-deGea, Jordi Casabona, Cristina Agustí

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