Early Diabetic Retinopathy Detection from OCT Images Using Multifractal Analysis and Multi-Layer Perceptron Classification by Ahlem Aziz, Necmi Serkan Tezel, Seydi Kaçmaz, Youcef Attallah

“…<b>Background/Objectives:</b> Diabetic retinopathy (DR) remains one of the primary causes of preventable vision impairment worldwide, particularly among individuals with long-standing diabetes. The progressive damage of retinal microvasculature can lead to irreversible blindness if not detected and managed at an early stage. …”
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Clinical application and evaluation of metagenomic next-generation sequencing in pathogen detection for suspected central nervous system infections by Lei Yuan, Xin Yu Zhu, Lan Min Lai, Qiang Chen, Yang Liu, Rui Zhao

“…Abstract Central nervous system Infections (CNSIs) is a disease characterized by complex pathogens, rapid disease progression, high mortality rate and high disability rate. …”
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Effectiveness of the California Mastitis Test (CMT), Reductase Test, and Alcohol Test for Dairy Cows Subclinical Mastitis Detection by Eriza Rosalina Rochmah, Dadik Raharjo, Sri Hidanah, Mustofa Helmi Effendi, Adiana Mutamsari Witaningrum, Sunaryo Hadi Warsito

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Predictive nomogram for early detection of invasive fungal disease deterioration --- a 10-year retrospective cohort study by Wei Wang, Yan Li, Hua Wang, Yumeng Du, Mengyuan Cheng, Jinyan Tang, Mingliang Wu, Chaomin Chen, Qingwen Lv, Weibin Cheng

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Artificial intelligence versus manual screening for the detection of diabetic retinopathy: a comparative systematic review and meta-analysis by Hasan Nawaz Tahir, Naseer Ullah, Mursala Tahir, Inbaraj Susai Domnic, Ramaprabha Prabhakar, Semmal Syed Meerasa, Ahmed Ibrahim AbdElneam, Ahmed Ibrahim AbdElneam, Shahnawaz Tahir, Yousaf Ali

“…BackgroundDiabetic retinopathy is one of the leading causes of blindness globally, among individuals with diabetes mellitus. Early detection through screening can help in preventing disease progression. …”
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Detection of genetic sex using a qPCR-based method in the bigfin reef squid (Sepioteuthis lessoniana) by Yi-Chien Lee, Li-Lun Tang, Yu-Chen Yeh, Hau-Wen Li, Huei-Mien Ke, Cheng-Ju Yang, Chun-I Chiang, Chia-Hui Wang, Yung-Che Tseng, Ching-Fong Chang, Isheng Jason Tsai, Guan-Chung Wu

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A Dynamic Adaptive Ensemble Learning Framework for Noninvasive Mild Cognitive Impairment Detection: Development and Validation Study by Aoyu Li, Jingwen Li, Yishan Hu, Yan Geng, Yan Qiang, Juanjuan Zhao

“… BackgroundThe prompt and accurate identification of mild cognitive impairment (MCI) is crucial for preventing its progression into more severe neurodegenerative diseases. …”
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Self-DSNet: A Novel Self-ONNs Based Deep Learning Framework for Multimodal Driving Distraction Detection by Mamun Or Rashid, Md. Mosarrof Hossen, Mohammad Nashbat, Mazhar Hasan-Zia, Ali K. Ansaruddin Kunju, Amith Khandakar, Azad Ashraf, Molla Ehsanul Majid, Saad Bin Abul Kashem, Muhammad E. H. Chowdhury

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Clinical Practice Guideline for detection and management of diabetic kidney disease: A consensus report by the Spanish Society of Nephrology by Nuria Montero, Laia Oliveras, Alberto Martínez-Castelao, José Luis Gorriz, María José Soler, Beatriz Fernández-Fernández, Maria Quero, Clara García-Carro, Paula Garcia-Sancho, Marian Goicoechea, Juan Jose Gorgojo Martínez, Pablo Molina, María Jesús Puchades, Diana Rodríguez-Espinosa, Nery Sablón, Rafael Santamaría, Juan Francisco Navarro-González

“…To address all the changes in the management of people with diabetes (DM) and chronic kidney disease (CKD), under the auspices of the Spanish Society of Nephrology (SEN), the Spanish Diabetic Nephropathy Study Group (GEENDIAB) decided to publish an updated Clinical Practice Guideline for detection and management of diabetic kidney disease (DKD). …”
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Fibroblast Growth Factor Receptor 4 Promotes Triple‐Negative Breast Cancer Progression via Regulating Fatty Acid Metabolism Through the AKT/RYR2 Signaling by Jinhui Ye, Song Wu, Qiang Quan, Feng Ye, Jinhui Zhang, Cailu Song, Yidan Fan, Huijiao Cao, Hailin Tang, Jianfu Zhao

“…However, the potential role and underlying mechanisms of FGFR4 in the progression of TNBC remain unclear. Methods Statistical analysis of FGFR4 expression data in public databases was used to reveal its role in TNBC. qRT‐PCR was used to detect FGFR4 expression levels. …”
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Anemia prevalence and associated factors among students benefiting from the rural compulsory education nutrition improvement program in Jilin province in 2023: a cross-sectional st... by Hongli CUI, Xingang ZHANG, Liwei ZHANG, Bo LUAN, Sijie LIU

“…ConclusionsThere are gender differences in the prevalence of anemia among students in the Nutrition Improvement Program areas of Jilin province. The influencing factors of anemia and the detection rates of anemia also vary by region. …”
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MST-AI: Skin Color Estimation in Skin Cancer Datasets by Vahid Khalkhali, Hayan Lee, Joseph Nguyen, Sergio Zamora-Erazo, Camille Ragin, Abhishek Aphale, Alfonso Bellacosa, Ellis P. Monk, Saroj K. Biswas

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Detecting the marine gastropod Lacuna vincta at seaweed farms using a novel environmental DNA (eDNA) assay by Cara A. Blaine, Thew Suskiewicz, Markus Frederich, Emily Rose Lancaster, Carrie J. Byron

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circPTN Promotes the Progression of Non-Small Cell Lung Cancer through Upregulation of E2F2 by Sponging miR-432-5p by Jiayuan Su, Jinrong Zhou, Yachan Feng, Haojie Zhang, Xinyu Zhang, Xiaorong Zhao, Yong Li, Xueling Guo

“…Quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting (WB) analysis were used to detect gene and protein expression, respectively. …”
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Earlier Diagnosis of Progressive Disease during Bevacizumab Treatment Using O-(2-F-Fluorethyl)-L-Tyrosine Positron Emission Tomography in Comparison with Magnetic Resonance Imaging by Norbert Galldiks, Marion Rapp, Gabriele Stoffels, Veronika Dunkl, Michael Sabel, Karl-Josef Langen

“…Positron emission tomography using the radiolabeled amino acid O-(2-[ 18 F]fluoroethyl)-L-tyrosine ( 18 F-FET-PET) may help detect the metabolically active tumor extent. We present 18 F-FET-PET imaging findings in a glioblastoma patient during bevacizumab treatment suggesting an earlier diagnosis of tumor progression than magnetic resonance imaging changes, which are based on the RANO criteria.…”
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Exosomal lncRNA H19 promotes the progression of hepatocellular carcinoma treated with Propofol via miR‐520a‐3p/LIMK1 axis by Dongmei Wang, Na Xing, Tao Yang, Junqi Liu, Huaping Zhao, Juan He, Yanqiu Ai, Jianjun Yang

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A Matter of Time: Delayed Presentation and Rapid Progression from Gonadotropin-Independent to Gonadotropin-Dependent Precocious Puberty following Successful Treatment for a Leydig... by C. R. Naotunna, D. N. Siriwardana, B. C. Lakmini, M. Samarasinghe, N. Atapattu

“…Occasionally, it has been reported few children are progressed to gonadotropin-dependent precocious puberty (GDPP) after initial clinical and biochemical recovery. …”
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Local anesthetic ropivacaine inhibits non-small cell lung cancer progression by modulating the hsa_circ_0001320/miR-518a-5p axis by LiQun Cheng, RongRong Shen, Zhen Ma, Yuan Guo, Yi Peng

“…Abstract Objective This study investigated the possible mechanisms by which ropivacaine influences the progression of non-small cell lung cancer (NSCLC). Methods Plasmid vectors or oligonucleotides interfering with circ_0001320 or miR-518a-5p were transfected into ropivacaine-treated NSCLC cells, and circ_0001320 and miR-518a-5p levels were detected by RT-qPCR. …”
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circHIPK2 promotes malignant progression of laryngeal squamous cell carcinoma through the miR-889-3p/MCTS1/IL-6 axis by Yang-Guang Sun, Zhen-Kun Yu, Xi Chen, Si-Yao Zhang, Wan-Juan Wu, Kai Liu, Lei Cheng

“…Mechanistic studies showed that circHIPK2 competitively bound to miR-889–3p, elevated MCTS1 level, promoted IL-6 secretion, and ultimately accelerated the malignant progression of LSCC. In conclusion, an axis involving circHIPK2, miR-889–3p, MCTS1 and IL-6 regulates the malignant progression of LSCC. circHIPK2 expression may serve as a novel diagnostic and prognostic biomarker for LSCC.…”
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m6A Methylation Regulator RBM15-Mediated Upregulation of ITGBL1 mRNA Stability Aggravates Colon Adenocarcinoma Progression by Remodeling the Tumor Microenvironment by Jie Zhu, Dengliang Liu, Yingying Zou

“…We aimed to investigate the function of RBM15 in COAD progression and its underlying molecular mechanism. …”
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