Machine learning based algorithms for virtual early detection and screening of neurodegenerative and neurocognitive disorders: a systematic-review by Milad Yousefi, Matin Akhbari, Zhina Mohamadi, Shaghayegh Karami, Hediyeh Dasoomi, Alireza Atabi, Seyed Amirali Sarkeshikian, Mahdi Abdoullahi Dehaki, Hesam Bayati, Negin Mashayekhi, Shirin Varmazyar, Zahra Rahimian, Mahsa Asadi Anar, Daniel Shafiei, Alireza Mohebbi

“…Twelve ML algorithms were observed for dementia, showing promise in early detection. Eighteen ML algorithms were identified for Parkinson’s, each effective in detection and diagnosis. …”
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The added value of diagnostics to characterize age-specific patterns of respiratory viral infections and coinfections and to detect emerging threats by Alessandra Pierangeli, Ombretta Turriziani, Matteo Fracella, Roberta Campagna, Federica Frasca, Alessandra D’Auria, Carolina Scagnolari, Piergiorgio Roberto, Lilia Cinti, Gabriella D’Ettorre, Giancarlo Ceccarelli, Laura Petrarca, Raffaella Nenna, Fabio Midulla, Gioacchino Galardo, Guido Antonelli

“…Molecular diagnostic data should be integrated with surveillance programs to characterize seasonal circulation patterns of common respiratory viruses and to rapidly detect the next pandemic threat.…”
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The probability of lung cancer in patients with pulmonary nodules detected via low-dose computed tomography screening in China by Lan-Wei Guo, Zhang-Yan Lyu, Yin Liu, Qing-Cheng Meng, Li-Yang Zheng, Qiong Chen, Hui-Fang Xu, Rui-Hua Kang, Shu-Zheng Liu, Shao-Kai Zhang

“…Conclusions The model developed and validated in this study may be used to estimate the probability of lung cancer in nodules detected at baseline LDCT, allowing more efficient risk-adapted follow-up in population-based LCS programs. …”
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Genomics-based approach for detection and characterization of SARS-CoV-2 co-infections and diverse viral populations by Bryan Jimenez-Araya, Aurélie Gourgeon, Mélissa N'Debi, Taylor Thompson, Vanessa Demontant, Axel Simitambe, Michel Lau, Laure Boizeau, Patrice Bruscella, Pierre Cappy, Jean-Michel Pawlotsky, Slim Fourati, Christophe Rodriguez

“…The cohort included 41,224 serial nasopharyngeal swabs positive for SARS-CoV-2 RNA, prospectively collected between January 2021 and April 2022 as part of the French national surveillance program. Full-length genomes were sequenced by next-generation sequencing (COVIDseq). …”
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A Review and Meta‐Analysis of Biomarkers in Early‐Stage Osteoarthritis by Austin Lawrence, Joseph Boesel, Rogelio Martinez Aguilar, Drew Gryczewski, Ahmed Suparno Bahar Moni

“…This review highlights the critical role of serum biomarkers in OA detection and progression. Markers like IL‐6, COMP, and PIIANP offer significant potential for early diagnosis. …”
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Olfactory dysfunction as potential biomarker in neurodegenerative diseases: a narrative review by Nicolas De Cleene, Katarína Schwarzová, Samuel Labrecque, Clancy Cerejo, Atbin Djamshidian, Klaus Seppi, Beatrice Heim

“…Neurodegenerative diseases represent a group of disorders characterized by progressive degeneration of neurons in the central nervous system, leading to a range of cognitive, motor, and sensory impairments. …”
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Deteksi Daging Babi Pada Produk Bakso di Pusat Kota Salatiga Menggunakan Teknik Polymerase Chain Reaction by Fidia Fibriana, Tuti Widianti, Amin Retnoningsih, Susanti -

“…</p><p>PCR technique has the ability to be sensitive to the detection of the presence of pork in fresh meat and processed products are mixed with other materials. …”
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Nationwide conflict damage mapping with interferometric synthetic aperture radar: A study of the 2022 Russia–Ukraine conflict by Corey Scher, Jamon Van Den Hoek

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The Role of Chemokine (C‐C Motif) Ligand 7 (CCL7) in Hepatocellular Carcinoma: Expression, Function, and Mechanisms by Yangkun Luo, Fei Wan, Zhao Zhang, Zujun Qin, Yongjun Ren

“…Chemokine (C‐C motif) ligand 7 (CCL7), a chemokine protein, has been implicated in the progression of various cancers. Nonetheless, the specific role of CCL7 in HCC has yet to be elucidated. …”
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Late-onset Parry–Romberg syndrome in a patient with newly diagnosed HIV-2 infection by Claúdia Brazão, Dora Mancha, Lanyu Sun, Sofia Antunes-Duarte, Diogo de Sousa, Pedro de Vasconcelos, Luís Soares-de-Almeida, Paulo Filipe

“…We present a case of a 31-year-old woman, Fitzpatrick’s phototype V, who presented to our dermatology department with a 5-year history of linear atrophy of her right hemiface, which rapidly progressed during the first 2 years and then stabilized. …”
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ACHIEVEMENT OF MINIMAL DISEASE ACTIVITY AND PROGRESSION OF RADIOGRAPHIC CHANGES IN EARLY PSORIATIC ARTHRITIS ONE YEAR AFTER INITIATION OF TREATMENT IN «TREAT TO TARGET» STRATEGY (P... by E. Yu. Loginova, T. V. Korotaeva, A. V. Smirnov, A. D. Koltakova, E. L. Nasonov

“…In 29 out of 40 patients (72,5%), no radiographic progression was detected neither in the ES nor in the JSN; 13 out of 29 (45%) received MTX and 16 (55%) – MTX + BA. …”
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The P2X7R-antagonist AFC-5128 ameliorates chronic experimental autoimmune encephalomyelitis in a preventive and therapeutic paradigm by Robert Hoffrogge, Anna Karachunskaya, Neele Heitmann, Steffen Haupeltshofer, Xiomara Pedreiturria, Katharina Klöster, Verian Bader, Konstanze F. Winklhofer, Michael Hamacher, Bert Klebl, Ralf Gold, Klaus Dinkel, Ingo Kleiter, Ingo Kleiter, Simon Faissner

“…BackgroundMultiple sclerosis (MS) is characterized by chronic inflammation driven by central nervous system (CNS)-resident immune cells such as microglia, especially during the progressive phase of the disease. The P2X7 receptor (P2X7R), a risk protein for MS, is ubiquitously expressed on immune cells. …”
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Formation of a comprehensive rehabilitation program for patients considering the clinical and diagnostic features of the course of vertebral thoracic pain due to degenerative-dystr... by Ye. I. Maramukha

“…According to the results of the Spearman correlation analysis the progression of signs of mental disorders is directly proportionally associated with the intensity of manifestations of myofascial syndromes due to DDPS, as showed statistically significant relationships between the values of the results of the Spielberger anxiety and Montgomery–Asberg depression rating scales, on the one hand, and the integral indicator of the cumulative thoracic vertebral-mechanical index (Rs = +0.69 and +0.78 at p < 0.01 for all cases), confirming the important pathogenetic relationship between these pathological processes, which indicates the urgent need for rehabilitation measures according to generally accepted (A. …”
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TRENDS IN DISEASE ACTIVITY, FUNCTIONAL STATUS, AND RADIOGRAPHIC CHANGES IN EARLY RHEUMATOID ARTHRITIS: RESULTS OF A 5-YEAR FOLLOW-UP WITHIN THE RUSSIAN RADIKAL PROGRAM by Yu. A. Ermakova, D. E. Karateev, E. L. Luchikhina, N. V. Demidova

“…Rheumatoid factor was found in 67.5% of the patients and anti-cyclic citrullinated peptide antibodies were detected in 57%. 86.5% of patients were female; median age was 49 [40; 58] years. …”
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Predictive Value of the Alberta Stroke Program Early CT Score (ASPECTS) in the Outcome of the Acute Ischemic Stroke and Its Correlation with Stroke Subtypes, NIHSS, and Cognitive I... by Ahmed Esmael, Mohammed Elsherief, Khaled Eltoukhy

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Dysregulated lipid metabolism in late preterm low birth weight neonates: A case-control study on maternal lipid levels and early metabolic programming implications by Jing Liu, Lijuan Tang, Qi Sun, Di Lv, Yuanmei Chen, Fang Ye, Die Liu, Qin Hui, Haixiao Liang, Chao Wang, Qi Zhang

“…Result A total of 1,173 lipids were identified, categorized into five major lipid classes, with 349 significantly different lipids detected (324 upregulated and 25 downregulated) in the LPTB-LBW group. …”
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Single-cell RNA sequencing reveals SLC31A1-mediated M2 polarization of macrophages promotes malignant progression in triple-negative breast cancer by Xiwei Zhang, Guoqing Li, Tieyan Chen, Haohang Sun, Ji Dai, Qi Chen, Mengze Chen, Meidi Yan

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Research Progress and Future Perspectives on Photonic and Optoelectronic Devices Based on p-Type Boron-Doped Diamond/n-Type Titanium Dioxide Heterojunctions: A Mini Review by Shunhao Ge, Dandan Sang, Changxing Li, Yarong Shi, Qinglin Wang, Dao Xiao

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Detection of the Liman tick virus (unclassified <i>Chuviridae</i>) in tick cell line HAE/CTVM8 by Alexander G. Litov, Alexey M. Shchetinin, Ivan S. Kholodilov, Oxana A. Belova, Аnna S. Kalyanova, Vladimir A. Gushchin, Galina G. Karganova

“…The final assembly of the virus genome was carried out in the Ugene program. Sequence alignment was performed by the MAFFT program. …”
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A novel method for the detection of Cas9 gRNAs using a fluorophore-labeled DNA oligo by Ranmal Avinash Bandara, Zhichang Peter Zhou, Ziyan Rachel Chen, Rongqi Duan, Alan Richard Davidson, Amy P. Wong, Jim Hu

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