Helicobacter pylori induced miR-362-5p upregulation drives gastric cancer progression and links hepatocellular carcinoma through an exosome-dependent pathway by Jianhui Zhang, Shuzhen Liu, Juan Zhang, Mingzhu Feng, Shu Chen, Yinuo Zhang, Zekun Sun, Xinying Cao, Chao Gao, Xiaofei Ji, Xiaofei Ji, Huilin Zhao, Huilin Zhao

“…MKN45 xenograft model in nude mice was employed to evaluate impacts of miR-362-5p on GC progression in vivo. Target gene of miR-362-5p was screened by bioinformatic analysis and verified by using dual-luciferase assay. …”
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Identifying Hub Genes and Immune Cell Infiltration for the Progression of Carotid Atherosclerotic Plaques in the Context of Predictive and Preventive Using Integrative Bioinformati... by Han Zhang, Yinde Huang, Xin Li, Wenbin Chen, Yu Lun, Jian Zhang

“…Here, the expression profiles of the genes expressed during the progression of the carotid atherosclerotic plaques were retrieved from the Gene Expression Omnibus database and 178 differentially expressed genes were examined. …”
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Single cell qPCR reveals that additional HAND2 and microRNA-1 facilitate the early reprogramming progress of seven-factor-induced human myocytes. by Emre Bektik, Adrienne Dennis, Prateek Prasanna, Anant Madabhushi, Ji-Dong Fu

“…In conclusion, HAND2 and microRNA-1 could help 7 factors to facilitate the early progress of iCM-reprogramming from human fibroblasts. …”
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Progressive Increase of Inflammatory CXCR4 and TNF-Alpha in the Dorsal Root Ganglia and Spinal Cord Maintains Peripheral and Central Sensitization to Diabetic Neuropathic Pain in R... by Dan Zhu, Tingting Fan, Xinyue Huo, Jian Cui, Chi Wai Cheung, Zhengyuan Xia

“…Moreover, CXCR4 and TNF-α of spinal cord dorsal and dorsal root ganglia (DRG) were detected by western blotting and immunostaining over time. …”
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CircSEC24A induces KLF8 expression to promote the malignant progression of non‐small cell lung cancer by regulating miR‐1253 by Wei Xiong, Jinhua Yang

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Hsa-circVIM regulates breast cancer tumor progression and tamoxifen sensitivity by sponging miR-1294 in hormone receptor-positive breast cancer cells by Ying Chen, Zhenhua Zhang, Xue Luo, Meini Cen, Peng Dai, Xiaoyan Zhu

“…Abstract Background The progression and metastasis of breast cancer patients are regulated by genetics and epigenetics. …”
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Ubiquitin specific peptidase 11 knockdown slows Huntington’s disease progression via regulating mitochondrial dysfunction and neuronal damage depending on PTEN-mediated AKT pathway... by Bai Gao, Yuchen Jing, Xi Li, Shuyan Cong

“…Conclusions Collectively, USP11 knockdown protects R6/1 mouse neurons from oxidative stress by alleviating mitochondrial dysfunction, thereby preventing the HD progression. This is achieved by inhibiting PTEN expression, which in turn activates the AKT pathway. …”
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RETRACTED: Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach by Geovanny Genaro Reivan Ortiz, Carmen Iulia Ciongradi, M. V. N. L. Chaitanya, Jayasankar Narayanan, Mohamed Mohany, Salim S. Al-Rejaie, José Luis Arias-Gonzáles, Ioan Sârbu, Marjan Assefi, Shaik Vaseem Akram, Yusuf Döğüş, Abolfazl Bahrami, Reza Akhavan-Sigari, Reza Akhavan-Sigari

“…Therefore, targeting the IL-33/ST2 axis could have potential value in the prevention of OvC progression.…”
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Predictive Value of Kidney Failure Risk Equation and Neutrophil Gelatinase-Associated Lipocalin for Chronic Kidney Disease Progression in Chinese Population – A Retrospective... by Shi L, Liao Y, Chen Y

“…The AUC of the 4-variable KFRE plus NGAL was significantly higher than those of the 4-variable KFRE and NGAL alone (0.900 vs 0.711, Z = 6.297, P < 0.001; 0.900 vs 0.736, Z = 5.795, P < 0.001), and the AUC of the 8-variable KFRE plus NGAL was also significantly higher than those of the 8-variable KFRE and NGAL alone (0.911 vs 0.725, Z = 6.491, P < 0.001; 0.911 vs 0.736, Z = 6.298, P < 0.001).Conclusion: The KFRE was able to independently predict progression of CKD stage 3– 5 to ESRD in Chinese population. …”
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Discontinuation of immune checkpoint inhibitors for reasons other than disease progression and the impact on relapse and survival of advanced melanoma patients. A systematic review... by Konstantinos Lallas, Eftychia Chatziioannou, Derya Durak, Georg Frey, Lina Maria Serna-Higuita, Marie-Lena Rasch, Athanassios Kyrgidis, Eleni Timotheadou, Zoe Apalla, Ulrike Leiter, Lukas Flatz, Lukas Flatz, Aimilios Lallas, Teresa Amaral, Teresa Amaral

“…From 2542 patients discontinued treatment with ICIs electively or due to TLTs, 495 experienced progression [number of studies (n)=34, RR 20.9%, 95%CI 17.1 – 24.7%, I2 85%) and higher rates were detected in patients with TLTs compared to elective discontinuation. …”
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Alzheimer’s Disease Detection from Retinal Images Using Machine Learning and Deep Learning Techniques: A Perspective by Adilet Uvaliyev, Leanne Lai Hang Chan

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Pathological Insights into Liquid Biopsy: Role of Circulating Tumor DNA in Oral Cancer Prognosis and Therapy by Raima Kalhoro, Fatima Sarfraz, Shahzaman Memon, Ayesha Atique, Sajid Ali Majeedano, Muqaddas Fatima, Kanwal Ehsan Khan

“…Circulating tumor DNA (ctDNA) represents a non-invasive biomarker through liquid biopsy because it enables cancer detection disease monitoring and therapy response assessment. …”
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Basketball free throw hit probability prediction system based on deep learning object detection and pose estimation by Hao Deng

“…With the rapid progress of artificial intelligence, deep learning technology has been extensively adopted in sports. …”
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Evaluation of Cell-Free DNA Long Fragments in the Triage of FIT+ Patients Enrolled in a Colorectal Cancer Screening Program: An Italian Prospective, Cross-Sectional Study by Mauro Scimia, Francesco Pepe, Gianluca Russo, Umberto Malapelle, Simone Scimia, Annalaura Alfieri, Valentina Olivieri, Rachel Chuang, Hiromi Tanaka, Michael Sha, David Chen, Claudia Scimone, Lucia Palumbo, Shuo Shen, Yulia Gavrilov, Stav Edelstein, Maria Antonia Bianco, Giancarlo Troncone

“…Introduction: Colorectal cancer screening programs are effective in reducing incidence and mortality. …”
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The Distinct Ultrasound Characteristics and Prognostic Features of Insulin-Induced Lipohypertrophy: A Systematic Review by Yang H, Zhang L, Dong Q, She Y, Zhang Y, Cao M, Xu M, Chu S

“…However, its ultrasound characteristics, classification, and progression patterns remain poorly understood. This review aimed to systematically analyze the ultrasound characteristics and progression patterns of LH, and explore the relationship between different LH types and clinical outcomes.Methods: A systematic literature search was conducted from January 2000 to October 2024 in PubMed, Web of Science, Embase, and Cochrane Library following PRISMA guidelines. …”
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Twitch force in human Amyotrophic Lateral Sclerosis by Laura Libonati, Chiara Cambieri, Marco Ceccanti, Federica Moret, Matteo Di Giulio, Eleonora Palma, Maurizio Inghilleri, Maurizio Inghilleri

“…These adaptations may preserve muscle function and elevate CK levels, suggesting better muscle integrity in slow progressors.ConclusionMuscle function profiles and CK levels are promising indicators of ALS progression. These findings could enhance early detection of disease progression and lead to targeted interventions to preserve muscle function. …”
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Fluorescent carbon quantum dots from Syzygium aromaticum as a selective sensor for Fe3+ and Cd2+ detection in aqueous solution by Said Ali Akbar, Muhammad Hasan, Muhammad Nazar, Ilham Zulfahmi, Edy Miswar, Muhammad Iqhrammullah, Zulkarnain Jalil

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Artificial intelligence MacHIne learning for the detection and treatment of atrial fibrillation guidelines in the emergency department setting (AIM HIGHER): Assessing a machine lea... by Kim Schwab, Dacloc Nguyen, GilAnthony Ungab, Gregory Feld, Alan S. Maisel, Martin Than, Laura Joyce, W. Frank Peacock

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Intelligent GPR Detection of Backfill Grouting Quality and Adjacent Soil Cavities in Shield Tunnels: A Case Study by Guangyuan Cai, Xiongyao Xie, Kang Li

“…This research advances the automation and intelligence of backfill grouting and cavity detection, supporting the safe and efficient progress of shield tunnel construction.…”
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Advancements in Circulating Tumor Cell Detection for Early Cancer Diagnosis: An Integration of Machine Learning Algorithms with Microfluidic Technologies by Ling An, Yi Liu, Yaling Liu

“…Several microfluidic techniques, including size-based filtration, dielectrophoresis, and immunoaffinity capture, have been developed to enhance CTC detection. The integration of machine learning (ML) with microfluidic systems has further improved the specificity and accuracy of CTC detection, significantly advancing the speed and efficiency of early cancer diagnosis. …”
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