Prognostic value of LncRNA SH3BP5-AS1 in non-small cell lung cancer and its regulatory effect on tumor progression by Cong Meng, Aihua Zang, Fengcai Du

“…CCK-8 was used to detect the proliferative viability of NSCLC cells. …”
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USP5‐dependent HDAC1 promotes cisplatin resistance and the malignant progression of non–small cell lung cancer by regulating RILP acetylation levels by Rongguo Lu, Yulin Jin, Mingfeng Zheng

“…Histone deacetylase 1 (HDAC1) has been implicated in the regulation of NSCLC progression; however, its role in the resistance of NSCLC to DDP remains unclear. …”
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Prospective exploration of the effect of adiposity and associated microbial factors on healing and progression of diabetic foot ulcers in Tanzania: study protocol of a longitudinal... by Fredirick Mashili, Agricola Joachim, Mabulla Mchembe, Faraja Chiwanga, Agbor Ako, Zulfiqar Abbas

“…The primary end point is complete wound healing at 24 weeks while secondary end points are ulcer progression (worsening or improving), amputation and death. …”
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LncRNA HOTTIP modulated by Hedgehog signaling drives colorectal cancer progression by promoting HUWE1-mediated ubiquitin‒proteasome degradation of p53 by Hui Wang, Weiwei Jiao, Defu Li, Zhengping Yu, Huqiao Luo, Jie Zhang, Yuanbing Zhang, Hai Rao, Quqin Lu, Bing Zhao, Shiwen Luo

“…Abstract The Hedgehog (Hh) pathway plays critical roles in regulating appropriate tissue morphogenesis and organ formation in the gastrointestinal tract, and its dysregulation has been closely linked to the malignant progression of colorectal cancer. However, the underlying mechanisms are poorly understood. …”
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Hsa_circ_0072088 promotes non-small cell lung cancer progression through modulating miR-1270/TOP2A axis by Sixuan Li, Zhigang Cui, Min Gao, Yanan Shan, Yihong Ren, Yuxin Zhao, Di Wang, Tingyu Meng, Hongxu Liu, Zhihua Yin

“…In conclusion, circ_0072088 is differentially highly expressed in non-small cell lung cancer and can affect the progression of non-small cell lung cancer through the circ_0072088/miR-1270/TOP2A axis.…”
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Detection of single nucleotide polymorphisms associated with litter size in goats using genotyping-by-sequencing and association analysis by Satoshi Kubota, Thara Wongdee, Pramote Paengkoum

“…Objective Improving fertility is a key goal in goat production. This study aimed to detect single nucleotide polymorphisms (SNPs) associated with female goat reproductive performance for use in selection processes. …”
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Prioritizing the Timely Detection and Diagnosis of Early-Age Onset Cancer to Enable Optimal Disease Management and Outcomes by Michael J. Raphael, Petra Wildgoose, Darren Brenner, Christine Brezden-Masley, Ronald Burkes, Robert C. Grant, Alexandra Pettit, Cassandra Macaulay, Monika Slovinec D’Angelo, Filomena Servidio-Italiano

“…In November 2024, the fourth annual Symposium focusing on early-age onset cancer (EAOC) was hosted by the Colorectal Cancer Resource & Action Network (CCRAN), assembling clinicians, researchers, and patients virtually to discuss challenges in early detection and diagnosis of individuals afflicted with EAOC across tumour types. …”
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Detection of Streptococcus pneumoniae serotypes causing invasive and non-invasive infections using whole-genome sequencing by Mironov К.O., Gaponova I.I., Korchagin V.I., Mikhailova Yu.V., Shelenkov A.A., Chagaryan A.N., Ivanchik N.V., Platonov A.E., Kozlov R.S., Akimkin V.G.

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Progression from isolated growth hormone deficiency to a combined pituitary hormone deficiency in a cohort of paediatrics patients with pituitary morphology abnormalities on MRI by Cristina Aguilar-Riera, Diego Yeste, Núria González-Llorens, Eduard Mogas, Ariadna Campos-Martorell, Paula Fernandez-Alvarez, Elida Vázquez, María Clemente

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USP8‐mediated PTK7 promotes PIK3CB‐related pathway to accelerate the malignant progression of non‐small cell lung cancer by Wencui Kong, Xuegang Feng, Zongyang Yu, Xingfeng Qi, Zhongquan Zhao

“…Macrophage M2 polarization was assessed by detecting CD206+ cells using flow cytometry. The interaction between PTK7 and USP8 or PIK3CB was assessed by Co‐IP assay. …”
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Glucose-lowering medications and glucose levels as the major determinants of progression of carotid atherosclerosis in middle-aged adults and elders: a community-based prospective... by Chao-Liang Chou, Chao-Liang Chou, Shu-Xin Lu, Chun-Fang Cheng, Tzu-Wei Wu, Li-Yu Wang

“…BackgroundFew prospective studies explored the incidence and determinant of carotid atherosclerosis (CA) progression (CAP). This community-based prospective study focused on the effects of diabetes mellitus (DM) treatments and glucose levels on CAP risks.MethodsWe followed up a group of 657 CA-positive middle-aged adults and elders for CAP. …”
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MiR-493-5p functions as a tumour suppressor in head and neck squamous cell carcinoma progression by targeting HIF-1α by Jiahui Liu, Ruxian Tian, Xi Chen, Qing Song, Caiyu Sun, Dongxian Li, Yuhui Fang, Shijun Lv, Yumei Li, Xicheng Song

“…Here, we explored the association of miR-493-5p with HNSCC progression and elucidated the underlying mechanisms. …”
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Clinico-pathological factors and [18F]FDG PET/CT metabolic parameters for prediction of progression-free survival in radioiodine refractory differentiated thyroid carcinoma by Nguyen Thi Phuong, Mai Hong Son, Mai Huy Thong, Le Ngoc Ha

“…The aim of this study was to investigate the prognostic value of clinico-pathological features and semiquantitative [18F]FDG PET/CT metabolic parameters in predicting progression-free survival (PFS) in DTC patients with RAI-R. …”
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Intraocular pressure correlation to progressive retinal nerve fiber layer loss in primary open angle glaucoma as measured by standard and modified goldmann applanation tonometers by Sean McCafferty, Manjool Shah, Anupam Laul, Khin Kilgore

“…Conclusions Higher levels of GAT IOP during follow-up were related to higher rates of progressive RNFL loss detected by optic nerve OCT in treated POAG. …”
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Seroprevalence of Antibodies to Plasmodium spp. among Individuals without Detectable Infection in Etsako, Edo State, Nigeria by Mathew Folaranmi Olaniyan, Felix Abayomi Adeoye, Wakili Adelani Tijani, Tolulope Busayo Olaniyan, Kemi Felicia Ajiboye, Medinat Taiwo Adeniran, Christian Onosetale Ugege, David Olufemi Adebo, Obataze Josephine Akpoyovwere, Odekunle Bola Odegbemi

“…Tailored malaria control strategies considering local immunity dynamics are crucial for sustaining progress in malaria elimination efforts in similar settings.…”
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Optimized Hybrid Deep Learning Framework for Early Detection of Alzheimer’s Disease Using Adaptive Weight Selection by Karim Gasmi, Abdulrahman Alyami, Omer Hamid, Mohamed O. Altaieb, Osama Rezk Shahin, Lassaad Ben Ammar, Hassen Chouaib, Abdulaziz Shehab

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Galaxy @Sciensano: a comprehensive bioinformatics portal for genomics-based microbial typing, characterization, and outbreak detection by Bert Bogaerts, Julien Van Braekel, Alexander Van Uffelen, Jolien D’aes, Maxime Godfroid, Thomas Delcourt, Michael Kelchtermans, Kato Milis, Nathalie Goeders, Sigrid C. J. De Keersmaecker, Nancy H. C. Roosens, Raf Winand, Kevin Vanneste

“…They are tailored for pathogens with active genomic surveillance programs, and clinical relevance, such as Escherichia coli, Listeria monocytogenes, Salmonella spp. and Mycobacterium tuberculosis. …”
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Detection and characterization of the Dezidougou virus (genus Negevirus) in mosquitoes (Ochlerotatus caspius) collected in the Republic of Sakha (Yakutia) by Marina A. Stepanyuk, Stanislav S. Legostaev, Kristina V. Karelina, Nina F. Timofeeva, Ksenia F. Emtsova, Olesia V. Ohlopkova, Oleg S. Taranov, Vladimir A. Ternovoi, Albert V. Protopopov, Valery B. Loktev, Victor A. Svyatchenko, Alexander P. Agafonov

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FGA-Corn: an integrated system for precision pesticide application in center leaf areas using deep learning vision by Zhongqiang Song, Zhongqiang Song, Wenqiang Li, Xuehang Song, Shun Li

“…This research not only achieves an efficient and accurate corn precision spraying program but also offers new insights and technological advances for intelligent agricultural machinery.…”
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Melanoma toolkit for early detection for primary care clinicians: a 1-year follow-up on outcomes by Kyra Diehl, Elizabeth Stoos, Alyssa Becker, Victoria E. Orfaly, Jacob Nelson, Jordan Gillespie, Justin Ng, Tayler Tobey, Tayler Tobey, Emile Latour, Emile Latour, Joanna Ludzik, Elizabeth G. Berry, Alan C. Geller, Heidi Jacobe, Justin Leitenberger, Danielle McClanahan, Jessica Tran, Smriti Prasad, Stephanie Mengden-Koon, Kelly C. Nelson, Ryan Petering, Alex Verdieck, Stephanie Savory, Emily H. Smith, Susan Tofte, Martin A. Weinstock, Martin A. Weinstock, Kevin White, Oliver Wisco, Oliver Wisco, Clara Curiel-Lewandrowski, Susan M. Swetter, Alexander M. Witkowski, Laura Ferris, Samantha Black, Rebecca Xu, Shuai Xu, Sancy Leachman, Sancy Leachman

“…Very few validated dermatology training programs exist for PCPs and those that are available focus primarily on one emphasis area, which results in variable efficacy and single-topic limited scope.MethodsWe have created a free, online, continuing education program (Melanoma Toolkit for Early Detection, MTED) that allows learners to choose from a variety of multimedia tools (image recognition, videos, written material, in-person seminars, self-tests, etc.) that suits their learning style and time availability. …”
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