Determination of Favipiravir in Human Blood Plasma by HPLC-MS/MS by T. N. Komarov, P. A. Karpova, O. A. Archakova, D. S. Shchelgacheva, P. K. Karnakova, N. S. Bagaeva, K. Ya. Zaslavskaya, P. A. Bely, I. E. Shohin

“…The aim of this study is to develop a method for quantitative determination of favipiravir in human blood plasma by HPLC-MS/MS for further for further researches of pharmacokinetics and bioequivalence of drugs.Materials and methods. In the process of sample preparation, a method of proteins precipitation with methanol was used. …”
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Coupling antitoxins and blue/white screening with parAB/resolvase mutation as a strategy for Salmonella spp. plasmid curing by Dereje D. Gudeta, Shaohua Zhao, Nesreen Aljahdali, Steven L. Foley

“…However, plasmid curing strategies targeting these systems are often hindered by the host addiction system through a process known as post-segregation killing. Here, we developed vector tools that can mutate the above systems while replenishing short-lived antitoxins. …”
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SentemQC - A novel and cost-efficient method for quality assurance and quality control of high-resolution frequency sensor data in fresh waters [version 1; peer review: 1 approved,... by Sofie Gyritia Madsen van't Veen, Joachim Audet, Eti Ester Levi, Brian Kronvang, Søren Erik Larsen, Erik Jeppesen, Esben Astrup Kristensen, Anders Nielsen, Thomas Alexander Davidson, Jane Rosenstand Laugesen, Peter Mejlhede Andersen

“…The growing use of sensors in fresh waters for water quality measurements generates an increasingly large amount of data that requires quality assurance (QA)/quality control (QC) before the results can be exploited. Such a process is often resource-intensive and may not be consistent across users and sensors. …”
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Fecal microbiota transplantation from postmenopausal osteoporosis human donors accelerated bone mass loss in mice by Tinglong Chen, Tinglong Chen, Ning Wang, Ning Wang, Yongqiang Hao, Yongqiang Hao, Lingjie Fu, Lingjie Fu

“…Aberrant gut microbiota might play a causal role in the process of bone mass loss mediated by inflammation after the destruction of the intestinal barrier.…”
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MORPHOLOGICAL CONDITION OF THE MUCOUS DURING THE PERIOD OF PHYSIOLOGICAL CHANGE OF THE CANINES OF THE UPPER JAW by M. Cholovskyi

“…According to our data, more pronounced dystrophic and sclerotic processes were detected during vestibular placement of retained canines; instead, the processes of compensation and adjustment were less pronounced.Objective of the study: to determine the morphological features of the structure of the gums from the vestibular and palatal surfaces during the physiological change of canines. …”
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Pengenalan Barang Pada Kereta Belanja Menggunakan Metode Scale Invariant Feature Transform (SIFT) by Ronny Makhfuddin Akbar, Nani Sunarmi

“…This can be overcome by using an object recognition or detection application based on image processing that will help speed up the process of scanning item at the cashier by scanning several items at the same time on the shopping cart and display the name, price, and total amount of shopping. …”
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Evaluating salivary MMP-8 as a biomarker for periodontal diseases: A systematic review and meta-analysis by Zsuzsanna Domokos, Fanni Simon, Eszter Uhrin, Bence Szabó, Szilárd Váncsa, Gábor Varga, Péter Hegyi, Beáta Kerémi, Orsolya Németh

“…Objective: Periodontitis is the irreversible destructive process of the periodontium and is the major cause of tooth loss in adults worldwide. …”
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Quantification and identification of microfibers released from textiles during simulated accelerated washing by João Pinto da Costa, Ana Costa, Andréa Marinho, Alcina Pimenta, Ana Paula Fonte, Ana L. Patrício Silva, António José Fernandes, Florinda M. Costa, Damià Barceló, Lúcia H.M.L.M. Santos, Armando Duarte, Teresa Rocha-Santos

“…As such, in this work, fibers from different fabrics were subjected to a simulated accelerated washing process to determine the release of microfibers into the resulting water following established and defined international standards. …”
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Integrated net pay cut-off evaluation workflow for tight sandstone reservoirs: a case study of the Linxing gas field, Ordos Basin by Li Li, Li Li, Jie Yu, Jie Yu, Tao Huang, Tao Huang, Lina Tang, Lina Tang, Dan Wei, Dan Wei, Mingyu Li, Mingyu Li, Xin Nie

“…Net pay detection is a crucial stage in reservoir characterization, serving various purposes such as reserve estimation, reservoir modeling, simulation, and production planning. …”
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Association of epigenetic aging with plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in Hispanic/Latino adults by Myriam Fornage, Wassim Tarraf, Martha L. Daviglus, Charles DeCarli, Kevin A. Gonzalez, Carmen R. Isasi, Sayaka Kuwayama, Melissa Lamar, Bonnie E. Levin, Humberto Parada, Alberto R. Ramos, Tatjana Rundek, Bharat Thyagarajan, Hector M. González

“…Abstract Background Blood-based biomarkers hold significant promise for the early detection and diagnosis of Alzheimer’s disease (AD) and other dementias. …”
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Peculiarities of chemo-resistant HIV/AIDS-associated tuberculosis in patients who died from co-infection by A. S. Shalmin, E. M. Raznatovskya, R. М. Yasinskiy

“…As it was noticed, the chronic process prevailed significantly (P <0.05) in patients who died from resistant co-infection. …”
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Binding of per- and polyfluoroalkyl substances with liver and serum proteins in rats: implications for physiologically based pharmacokinetic modelling by Xiarui Fan, Xiaomin Li, Tong Li, Bing Shao, Shan Niu, Wenhong Fan, Qi Wang, Lv Zhong, Xiangrui Wang, Ziwei Wang, Fujun Ma, Guomao Zheng, Hui Peng, Lili Chen, Zhaomin Dong

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Case Report: Unveiling the hidden: a rare case of endometrial tuberculosis presenting as peritoneal carcinomatosis by Mariem Garci, Mariem Garci, Mehdi Makni, Mehdi Makni, Ghada Abdelmoula, Ghada Abdelmoula, Amani Abdeljabbar, Amani Abdeljabbar, Wafa Babay, Nahla Ben Saada, Nahla Ben Saada, Fatma Dhieb, Fatma Dhieb, Linda Hadj Kacem, Linda Hadj Kacem, Nabil Mathlouthi, Nabil Mathlouthi, Cyrine Belghith, Cyrine Belghith, Olfa Slimani, Olfa Slimani

“…Moreover, peritoneal tuberculosis, although rare, can further complicate the diagnostic process due to its clinical manifestations that resemble those of various cancerous conditions. …”
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On the utility function of experiments in fundamental science by Tommaso Dorigo, Michele Doro, Max Aehle, Muhammad Awais, Nicolas R. Gauger, Rafael Izbicki, Jan Kieseler, Ann B. Lee, Luca Masserano, Federico Nardi, Alexander Shen, Luis Recabarren Vergara

“…The majority of experiments in fundamental science today are designed to be multi-purpose: their aim is not simply to measure a single physical quantity or process, but rather to enable increased precision in the measurement of a number of different observable quantities of a natural system, to extend the search for new phenomena, or to exclude a larger phase space of candidate theories. …”
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Chemical and isotopic signatures of hot springs from east-central Sonora State, Mexico: a new prospection survey of promissory low-to-medium temperature geothermal systems by Erika Almirudis, Edgar R. Santoyo-Gutiérrez, Mirna Guevara, Francisco Paz-Moreno, Enrique Portugal

“…Using geochemometric analyses of the fluid composition and fractionation, depletion and enrichment processes exhibited by major and trace elements were analysed. …”
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Identification and validation of efferocytosis-related biomarkers for the diagnosis of metabolic dysfunction-associated steatohepatitis based on bioinformatics analysis and machine... by Chenghui Cao, Chenghui Cao, Wenwu Liu, Xin Guo, Shuwei Weng, Yang Chen, Yonghong Luo, Shuai Wang, Botao Zhu, Botao Zhu, Yuxuan Liu, Yuxuan Liu, Daoquan Peng

“…BackgroundMetabolic dysfunction-associated steatohepatitis (MASH) is a highly prevalent liver disease globally, with a significant risk of progressing to cirrhosis and even liver cancer. Efferocytosis, a process implicated in a broad spectrum of chronic inflammatory disorders, has been reported to be associated with the pathogenesis of MASH; however, its precise role remains obscure. …”
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Proteomics of Urinary Extracellular Vesicles Highlight the Involvement of Vitronectin and the Fibrinolytic and TNF Pathways as Mechanisms Underlying Renal Fibrosis in Kidney Transp... by Marta Clos‐Sansalvador, Sergio G. Garcia, Paula Rodríguez‐Martínez, Marta Sanroque‐Muñoz, Miriam Font‐Morón, Cristina Grange, Benedetta Bussolati, Marcella Franquesa, Javier Juega, Francesc E. Borràs

“…This study highlights TNF‐induced inflammation involving macrophages and fibrinolysis as key mechanisms underlying renal fibrosis with direct implications of VTN, which support VTN's potential as a biomarker for this pathological process.…”
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Comparison of Crustal Stress and Strain Fields in the Himalaya–Tibet Region: Geodynamic Implications by Federico Pietrolungo, Giusy Lavecchia, Asier Madarieta-Txurruka, Federica Sparacino, Eshaan Srivastava, Daniele Cirillo, Rita de Nardis, Carlo Andrenacci, Simone Bello, Nicolò Parrino, Attilio Sulli, Mimmo Palano

“…The Himalaya–Tibet region represents a complex region of active deformation related to the ongoing India–Eurasia convergence process. To provide additional constraints on the active processes shaping this region, we used a comprehensive dataset of GNSS and focal mechanisms data and derived crustal strain and stress fields. …”
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Identifying hotspots and classifying the spatial distribution pattern of karst collapse pillars with Moran’s index in coal mine by Junsheng Yan, Junsheng Yan, Junsheng Yan, Zaibin Liu, Zaibin Liu, Zaibin Liu, Zaibin Liu, Hui Yang, Hui Yang, Hui Yang, Lin An, Lin An, Lin An, Wei Li, Tiantian Wang, Qian Xie, Qian Xie, Qian Xie, Chenguang Liu, Chenguang Liu, Chenguang Liu, Chenguang Liu

“…While previous studies have focused primarily on physical detection, the spatial clustering characteristics of KCPs have often been overlooked. …”
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Insight into Antiviral Activity of Ag/TiO2 Nanocomposites Against Influenza H1N1 Virus and Its Antiviral Mechanism by Ma Y, Xiao X, Wang Y, Sun J, Tang P, Li J, Sun X, Xu D, Yang Z, Chen S, Liu X

“…The antiviral activities and the antiviral mechanism of ATA were investigated in detail by light microscopy, transmission electron microscopy and biological techniques such as cell cytotoxicity, 50% tissue culture infectious dose detection, western blot and reverse transcription-polymerase chain reaction.Results: These results showed the successful synthesis of ATA nanocomposite with uniform particle size and distribution. …”
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