Immunological profiling in type 2 diabetes mellitus and type 2 diabetic kidney disease: insights from single-cell LacNAc sequencing by Mengyun Xiao, Zigan Xu, Xiaohui Zhu, Jing Chen, Ru Wang, Yaxuan Wang, Xiang Gao, Shaodong Luan, Xiaoyan Pu

“…Recently, the innate immune system, particularly neutrophils and the process of NET formation, has garnered significant attention for its role in the progression of T2DKD in patients with T2DM. …”
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Breast lesion classification via colorized mammograms and transfer learning in a novel CAD framework by Abbas Ali Hussein, Morteza Valizadeh, Mehdi Chehel Amirani, Sedighe Mirbolouk

“…Abstract Medical imaging sciences and diagnostic techniques for Breast Cancer (BC) imaging have advanced tremendously, particularly with the use of mammography images; however, radiologists may still misinterpret medical images of the breast, resulting in limitations and flaws in the screening process. As a result, Computer-Aided Design (CAD) systems have become increasingly popular due to their ability to operate independently of human analysis. …”
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IPEC-J2 Autophagy Induced by TLR4 and NSP6 Interactions Facilitate Porcine Epidemic Diarrhea Virus Replication by Haiyuan Zhao, Dianzhong Zheng, Qinyuan Chang, Hailin Zhang, Yilan Shao, Jiaxuan Li, Wen Cui, Yanping Jiang, Lijie Tang, Yijing Li, Xiaona Wang

“…However, some viruses have evolved mechanisms to hijack this defensive process to provide favorable conditions for virus replication in host cells. …”
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Dynamic changes in brain function during sleep deprivation: Increased occurrence of non-stationary states indicates the extent of cognitive impairment by Ziliang Xu, Chaozong Ma, Chen Wang, Fan Guo, Minwen Zheng, Peng Fang, Yuanqiang Zhu

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Ricin and Abrin as Possible Agents of Bioterror by D. V. Pechenkin, A. S. Gorshkov, M. A. Sablina, A. V. Eremkin, S. S. Ipatov, G. V. Kuklina

“…The mechanism of their damaging action is based on irreversible inhibition of the process of protein synthesis. The LD50 of ricin for humans, according to various sources, is 3 µg/kg for inhalation and intravenous intake, 22–25 µg/kg for enteral intake, and about 500 µg/kg for subcutaneous intake. …”
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Rapid Screening of 60 Types of Natural Toxins in Whole Blood by UPLC-Q/Orbitrap HRMS by GUO Zhu-tao, DENG Qian-ya, HE Si-yang, ZHENG Shui-qing, WANG Rong, SUN Wen-juan, LIANG Chen, NI Chun-fang

“…Except for the limit of detection （LOD） of oxymatrine （20 ng/mL） and strophanthidin （40 ng/mL）, the LOD for the other 58 natural toxins was in the range of 0.05-5 ng/mL.ConclusionThis method has a simple and efficient pretreatment process and can achieve rapid screening of 60 types of natural toxins in whole blood.…”
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Graduate Student Literature Review: Potential use of HSP70 as an indicator of heat stress in dairy cows—A review* by M.R.H. Rakib, V. Messina, J.I. Gargiulo, N.A. Lyons, S.C. Garcia

“…Traditional methods of measuring HSP70 in blood samples are labor intensive, and because the process is potentially stressful for the animals, this may subsequently affect the results. …”
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A streamlined workflow for long-read DNA methylation analysis with NanoMethViz and Bioconductor [version 2; peer review: 2 approved] by Kelsey Breslin, Shian Su, Tamara Cameron, James Lancaster, Lucinda Xiao, Matthew E. Ritchie, Peter F. Hickey, Quentin Gouil, Marnie E. Blewitt

“…Long-read sequencing technologies have transformed the field of epigenetics by enabling direct, single-base resolution detection of DNA modifications, such as methylation. …”
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Determination of 18 Amino Acids in Water by Solid Phase Extraction-Ultra Performance Liquid Chromatography-Tandem Triple Quadrupole Mass Spectrometry by Jin-han LIANG, Ze-hua LIU, Wan-qiong LIU, Yan-shan DONG

“…During chlorine disinfection, AAs can be converted to potentially biotoxic disinfection byproducts such as haloacetonitrile, halogenated nitroalkanes and haloamides. During the process of chlorine disinfection, chlorine rapidly reacts with the vast majority of free amino acids, particularly α-amino acids, forming organic monochloramines or dichloramines. …”
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Sustainable Practices and Microbial Quality of Cattle Offal in Slaughterhouses by Ana Raquel Cândido, Kamila Soares, Márcio Moura-Alves, Cristina Saraiva, Alexandra Esteves

“…This study was triggered by the scarcity of information on the microbiological quality of edible bovine offal, which is often associated with poor hygienic conditions during handling and processing at slaughterhouse. This study assessed the superficial microbiota present on cattle liver and tongue in a vertical slaughterhouse across various stages of the procurement process and on days with different slaughter volumes, with three sampling points: immediately after post-mortem inspection (Point 1); after the arrival of the viscera in the preparation room (Point 2); and in the refrigeration chamber at 3 °C (Point 3). …”
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COMBINED TREATMENT OF LOCALLY-ADVANCED BLADDER CANCER by I. V. Chernyshev, Y. V. Samsonov, D. V. Perepechin, A. M. Ulbashev

“…An objective response is possible in 44.7%, and the stabilization process in 40.4% of patients.Results. The clinical effect is evaluated in all patients. …”
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Influence of platelet-rich plasma on RANKL and IL-1 immunohistochemical expression in periodontitis-related bone cell proliferation and differentiation by Hana H. Mustafa, Snur M.A. Hassan, Sozan Ali Mohammed, Mardin O. Mohammed, Hadia Karim Zorab, Hardi Fattah Marif

“…The rats were sacrificed after both experiment durations (7 and 30 days), and the incisor teeth were fixed and decalcified in HCl for a day and in 10 % EDTA solution for eight weeks at room temperature then samples were processed for H&E stain for bone healing scores and bone cells counting, and the samples were utilized by IHC for detection of both RANKL and IL-1β expression. …”
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A Fast Image Segmentation Algorithm Based on Saliency Map and Neutrosophic Set Theory by Sensen Song, Zhenhong Jia, Jie Yang, Nikola K. Kasabov

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OS-PCMM: Automatic Registration Algorithm for Optical and SAR Image Based on Phase Congruency and Multimoment Feature by Yuan Liang, Tao Su, Ruiqiu Wang, Jiangtao Liu

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An Effective and Fast Model for Characterization of Cardiac Arrhythmia and Congestive Heart Failure by Salim Lahmiri, Stelios Bekiros

“…The kNN yielded 97% accuracy, 99% sensitivity, 90% specificity and 0.63 s processing time when classifying ARR against NS, and it yielded 99% accuracy, 99.7% sensitivity, and 99.2% specificity, and 0.27 seconds processing time when classifying HCF against NS. …”
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IIoT’s Risk Odyssey: Navigating the Risk Propagation of Illegal Information Flows by Argiro Anagnostopoulou, Ioannis Mavridis, Michael Athanasopoulos, Alexios Mylonas, Dimitris Gritzalis

“…As a result, it is crucial to establish more robust security measures, enforce more effective access control policies, and efficiently manage information flows within business processes. In our prior research, we introduced a methodology for the assessment of information flows in IIoT environments and the detection of the illegal ones. …”
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Comparison of Manhattan and Chebyshev Distance Metrics in Quantum-Based K-Medoids Clustering by Solikhun Solikhun, Muhammad Rahmansyah Siregar, Lise Pujiastuti, Mochamad Wahyudi, Deny Kurniawan

“…Quantum computers, which utilize the principles of quantum mechanics for information processing, have made significant advancements over the past decade. …”
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Developing an Algorithm for Robotic Precision Application of Crop Protection Products by M. A. Mirzaev

“…(Materials and methods) A robotic device has been developed for variable rate application of plant protection products able to recognize both useful crops and weeds, determine the area of processing, namely the coordinates of the processing center and the processing radius. …”
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The Alarming State of Hepatitis B Vaccination Among Dentists: Local, National and Global Implications by Muhammad Usman Sultan, Ihsan Ullah, Muhammad Anas

“…After screening, 68(22.7%) were detected positive for HBsAg, while the ratio of HCV-positive patients was found positive in 65 (21.7%) cases4. …”
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Investigation of the Prevalence of Infectious Myonecrosis Virus (IMNV) from 2022 to 2023 by Ruidong XU, Jitao XIA, Ping LI, Xingtong YU, Liang YAO, Wenqiang LI, Tianchang JIA, Qingli ZHANG

“…The results of this study indicated a high positive rate of IMNV in cultured shrimp, biological live bait, and offshore seawater in many Chinese provinces between 2022–2023. Detection, monitoring, and early warning of IMNV infection in the shrimp farming process should be strengthened to reduce the risk of further spread and IMN epidemics.…”
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