A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds. by Claire J Cairney, Lauren S Godwin, Alan E Bilsland, Sharon Burns, Katrina H Stevenson, Lynn McGarry, John Revie, Jon D Moore, Ceri M Wiggins, Rebecca S Collinson, Clare Mudd, Elpida Tsonou, Mahito Sadaie, Dorothy C Bennett, Masashi Narita, Christopher J Torrance, W Nicol Keith

“…As such, interest in the use of senescence-induction in a therapeutic context has been gaining momentum in the past few years; however, senescence and immortalisation remain underserved areas for drug discovery owing to a lack of robust senescence inducing agents and an incomplete understanding of the signalling events underlying this complex process. In order to address this issue we undertook a large-scale morphological siRNA screen for inducers of senescence phenotypes in the human melanoma cell line A375P. …”
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Assistive Devices Analysis for Visually Impaired Persons: A Review on Taxonomy by Sadia Zafar, Muhammad Asif, Maaz Bin Ahmad, Taher M. Ghazal, Tauqeer Faiz, Munir Ahmad, Muhammad Adnan Khan

“…In the second stage, state of the art machine learning techniques process these signals and extract useful information. …”
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Fuzzy Rule-Based Combination Model for the Fire Pixel Segmentation by Alberto Lopez-Alanis, Hector de-la-Torre-Gutierrez, Arturo Hernandez-Aguirre, Maria T. Orvananos-Guerrero

“…This has resulted in a lack of consensus on the thresholds determined by various researchers, even when the same color space is used during the examination process. Additionally, determining fire pixels in a binary manner complicates the handling of uncertainty and vagueness in color information. …”
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Back pain in therapeutic practice by N. A. Varavin, А. L. Vertkin

“…In addition, there should be no specific signs of involvement in the process of the roots of the spinal nerves and stenosis of the spinal canal. …”
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Morphological features of vascular lesions of the microvasculature in sepsis by V. S. Chirskij, E. A. Andreeva, A. K. Yuzvinkevich

“…Regardless of the severity of the purulent metastatic process, septic lesions are characterized by the same changes in the microvasculature, expressed in increased expression of adhesive molecules by the endotheliocytes (ICAM-1), desquamation of endotheliocytes (51 %), marginal standing of leukocytes (38 %), the output of single leukocytes beyond the vessels (21 %), leukocyte stasis (55 %), the formation of fibrin and hyaline microtrombi (45 %), the sludge phenomenon (91 %), diapedetic hemorrhage in the tissues (72 %), which indicate a leading role in microcirculation disorders and, correspondingly, the formation of multiple organ failure during sepsis of secondary microvascular damage. …”
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Biological evaluation of semi-synthetic isoindolinone isomers produced by Stachybotrys chartarum by Alica Fischle, Alica Fischle, Ulrich Schreiber, Viola Haupt, Felix Schimang, Lina Schürmann, Matthias Behrens, Florian Hübner, Melanie Esselen, Dmitrii V. Kalinin, Svetlana A. Kalinina, Svetlana A. Kalinina

“…Ultimately, each isomer can be distinguished already during the purification process, which extends to the biological assays where we present one less cytotoxic, faster metabolized, and more active regio-isomeric phenylspirodrimane-derivative.…”
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Quantifying spatio-temporal changes in the ecological environment quality and their implications for surface mass movement after a high-magnitude earthquake by Ming Chen, Chuan Tang, Yu Yang, Jiang Xiong

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Enhancing Incentive Schemes in Edge Computing through Hierarchical Reinforcement Learning by Gowtham R, Vatsala Anand, Yadati Vijaya Suresh, Kasetty Lakshmi Narasimha, R. Anil Kumar, V. Saraswathi

“…The bottom layer identifies and excludes malicious or lazy nodes that negatively impact the education process. By tackle both short-term and long-term objectives Chiron ensures fairness and performance stability. …”
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BFER-Net: Babies Facial Expression Recognition Model Using ResNet12 Enabled Few-Shot Embedding Adaptation and Convolutional Block Attention Modules by Sumiya Arafin, Adnan Ferdous Ashrafi, Md. Golam Rabiul Alam, Ashis Talukder

“…Here, we have deployed the feature extraction process. A Convolutional Block Attention Module (CBAM) was integrated into the Modified ResNet12 architecture. …”
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Spatial differentiation and influencing factors of heavy metals in soils of typical counties in Lhasa river basin by Haichuan Lu, Xin Yuan, Cang Gong, Jiufen Liu, Youchang Shi, Xiang Xia

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Optimized fiducial marker placement using B‐spline surface modeling and graph theory for Cyberknife stereotactic body radiotherapy for superficial tumors by Jing Huang, Xianlong Xiong, Cheng Chen, Yuhan Li, Ruijie Wang, Zhitao Dai

“…The experimental results showed that our algorithm could efficiently plan fiducial marker placement, thereby simplifying the planning process and providing valuable technical support for CyberKnife treatments.…”
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Paper based analytical platforms: A matrix adaptable approach to drug testing by Naga Prashant Koppuravuri, Suvarna Yenduri, Rukaiya Nabi, Pooja M, Aishwarya N, Sanika M, Sinchana Prakash

“…This study evaluates the potential applications of PADs in drug testing with a particular emphasis on the adaptability of PADs in terms of their ability to handle various types of samples during the testing process. In this study, the design, manufacturing, and performance of PADs for drug detection, as well as the influence that different biological samples have on the performance of PAD performance were investigated. …”
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Innovative Ghost Channel Spatial Attention Network with Adaptive Activation for Efficient Rice Disease Identification by Yang Zhou, Yang Yang, Dongze Wang, Yuting Zhai, Haoxu Li, Yanlei Xu

“…This model not only enables efficient and accurate real-time disease monitoring but also provides a viable solution for rice field protection drones and Internet of Things management systems, advancing the process of contemporary agricultural smart management.…”
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Land-sea Clutter Classification Method Based on Multi-channel Graph Convolutional Networks by Can LI, Zengfu WANG, Xiaoxuan ZHANG, Quan PAN

“…Land-sea clutter classification is essential for boosting the target positioning accuracy of skywave over-the-horizon radar. This classification process involves discriminating whether each azimuth-range cell in the Range-Doppler (RD) map is overland or sea. …”
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CASES OF DIFFUSE LARGE B-CELL LYMPHOMA WITH FUNCTIONAL INTRON MUTATIONS IN THE TP53 GENE by E. N. Voropaeva, M. I. Voevoda, T. I. Pospelova, V. N. Maksimov

“…Mutations in the TP53 gene are the driver of the tumor process, serve not only as a marker of aggressive tumor progression, but also as an independent predictor of reduced sensitivity to treatment. the presented clinical cases show that an in-depth analysis of the results of the TP53 sequencing in tumors and functional assessment of all detected changes, including changes in the introns of the gene and involving in silico analysis techniques, are necessary.…”
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A Terpyridine Based 1,2,3‐Triazol‐1,4‐diyl‐Fluoroionophore‐A Fluorometric Study Towards 3d Metal Ions in Acetonitrile by Thomas Schwarze, Holger Müller, Eric Sperlich, Alexandra Kelling, Hans‐Jürgen Holdt

“…A modulation of the ICT process in 1 through Fe2+, Co2+, Cu2+, Ni2+ and Zn2+ leads to a small red shift of the lowest energetically lying absorption UV/Vis absorption band and to a very strong 3d metal ion induced fluorescence quenching. …”
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The effectiveness of interventions used to improve general health check uptake by the older adult population: a systematic review and meta-analysis. by Wing Yan Lau, Jinxiao Lian, Maurice Yap

“…Undergoing general health check enable early detection of common diseases and giving individuals a sense of control over their wellbeing. …”
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Recycled newspaper cellulose based colorimetric sensor of biogenic amines for food spoilage indication by Atitiya Saedan, Tatiya Siripongpreda, Nadnudda Rodthongkum, Sarute Ummartyotin

“…Cellulose was extracted from newspaper waste and purified by alkali treatment process. The white color cellulose without ink and glue was obtained and then characterized by Fourier transform infrared spectroscopy and X-ray diffraction spectroscopy. …”
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Comparison of Methods for Extraction of Infectious Influenza Virus from Raw Milk Cheeses by Madeleine Blondin-Brosseau, Wanyue Zhang, Caroline Gravel, Jennifer Harlow, Xuguang Li, Neda Nasheri

“…We used murine norovirus (MNV) as a surrogate for human norovirus and also as a process control virus and examined the efficacy of the employed methods by plaque assay. …”
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Explainable light-weight deep learning pipeline for improved drought stress identification by Aswini Kumar Patra, Aswini Kumar Patra, Lingaraj Sahoo

“…Comparative analysis of existing state-of-the-art object detection algorithms reveals the superiority of our approach in achieving higher precision and accuracy. …”
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