Automatic Aortic Valve Extraction Using Deep Learning with Contrast-Enhanced Cardiac CT Images by Soichiro Inomata, Takaaki Yoshimura, Minghui Tang, Shota Ichikawa, Hiroyuki Sugimori

Get full text

Leveraging Digital Innovations to Combat Antimalarial Resistance in South and East Africa by Dr Stephanie Van Wyk, Dr Ishen Seocharan, Dr Eulambius Mlugu, Dr Donnie Mategula, Ms Tikhala Makhaza, Prof. Karen Barnes

“…Methods: These technologies, implemented using open-access tools such as REDCap, BotPress, and PowerBi, enhanced the capabilities of national malaria control programs and stakeholders in 18 malaria-endemic countries. …”
Get full text

Development of a 3D-Printed Chest Phantom with Simulation of Lung Nodules for Studying Ultra-Low-Dose Computed Tomography Protocols by Jenna Silberstein, Steven Tran, Yin How Wong, Chai Hong Yeong, Zhonghua Sun

“…An optimal protocol of 80 kVp and 30 mAs was identified for lung nodule detection, delivering a dose of only 0.23 mSv, which represents a 96% reduction compared to standard CT protocols. …”
Get full text

Clinical Characteristics and Treatment Outcomes of Colorectal Cancer in Jordan, a Resource-Restricted Country by Hikmat Abdel-Razeq, Maha Barbar, Sarah Abdel-Razeq, Fawzi Abuhijla, Issa Mohamad, Kamal Al-Rabi, Akram Al-Ibraheem, Hazem Hammad, Asem Mansour

“…After a median follow-up of 49 months, the 5-year OS for the whole group was 53.9% (95% CI, 52.0% to 55.8%) and varied by disease stage; 87.7% (95% CI, 80.3% to 93.5%) for stage I, 84.7% (95% CI, 81.3% to 87.9%) for stage II, 69.9% (95% CI, 67.0% to 72.8%) for stage 3, and only 14.5% (95% CI, 12.2% to 16.9%) for patients with stage IV disease, P < .0001.CONCLUSIONOne third of all patients with colorectal cancer are diagnosed with metastatic disease, which explains the lower survival rates observed compared with Western countries. Programs and initiatives focused on the prevention and early detection of colorectal cancer should be a national priority.…”
Get full text

Molecular epidemiology and genotype distribution of genital high-risk human papillomavirus among women in North–East India by Jayanta Ray, Jaharlal Baidya, Dhruba P. Paul, Gautam Majumdar, Shiromani Debbarma, Atanu Sarkar, Manidipa Chakma, Manash P. Barman, Matrujyoti Pattnaik, Ankita Debnath, Sukanta Nath

“…In contrast, the prevalence of HPV 18 was considerably lower. The only HR-HPV detected in elderly patients was HPV 16 (≤ 60). This study provides important epidemiological data on the prevalence of cervical HPV infection, which can serve as a useful reference for cervical cancer screening programs and developing nationwide HPV vaccination.…”
Get full text

Intrathecal drug delivery systems: A case series advancing surgical, clinical, and technological safety with broader implications for invasive neuromodulation therapies by Bi Mo, Sandra Sacks, Jerry Markar

“…Invasive neuromodulation therapies, including intrathecal drug delivery systems, present multifaceted challenges that necessitate rigorous patient and therapeutic agent selection, meticulous risk factor mitigation, continuous neuromonitoring, and prompt detection of subtle neurological changes indicative of potential complications. …”
Get full text

Deep metabolic profiling of immune cells by spectral flow cytometry—A comprehensive validation approach by Claire L. Wishart, Alanna G. Spiteri, Jian Tan, Claudio Counoupas, James A. Triccas, Laurence Macia, Nicholas J.C. King

“…Additionally, leveraging NAD(P)H autofluorescence allowed label-free detection of glycolysis and expanded the panel’s utility. …”
Get full text

Bordetella pertussis diagnosis in children under five years of age in the Regional Hospital of Cajamarca, Northern Peru by Juana del Valle-Mendoza, Veronica Casabona-Oré, Veronica Petrozzi-Helasvuo, Angela Cornejo-Tapia, Pablo Weilg, Maria J Pons, Erico Cieza-Mora, Jorge Bazán-Mayra, Hernan Cornejo-Pacherres, Joaquin Ruiz

“…Nasopharyngeal samples were obtained for B. pertussis culture and polymerase chain reaction (PCR) detection. Results: In 133 children, the pertussis toxin and IS481 gene were detected in 38.35% (51/133) of the cases by PCR, while only 9.02% (12/133) of the Bordetella cultures were positive. …”
Get full text

Antimicrobial resistance among group B Streptococcus and Staphylococcus aureus isolates from bovine mastitis in Brazil over 35 years by Dr Tatiana Pinto, Juliana Ribeiro, Dr Laura Oliveira, Leandro Simões, Dr Natalia Costa, Prof José Carlos Pantoja, Prof Renata Rabello, Prof Lucia Teixeira, Prof Ruth Zadoks

“…The lack of mastitis management programs leads to the unnecessary use of broad-spectrum antibiotics, which fosters the rise of antimicrobial resistance (AMR). …”
Get full text

Peran Intelijen Keamanan Dalam Pencegahan Dan Penanggulangan Tindak Pidana Terorisme by Suman Sirait, Junaidi Abdillah

“…The urgency lies in the critical need to strengthen the role of regional intelligence as the front line in early detection and counter-radicalization efforts. The research method employs a normative juridical approach, utilizing legal and conceptual frameworks, and is analyzed through a descriptive-qualitative lens. …”
Get full text

Community health workers for non-communicable diseases prevention and control in developing countries: Evidence and implications. by Gursimer Jeet, J S Thakur, Shankar Prinja, Meenu Singh

“…<h4>Background</h4>National programs for non-communicable diseases (NCD) prevention and control in different low middle income countries have a strong community component. …”
Get full text

Transforming Breast Cancer Care: Overcoming Rural Challenges in Pakistan by Syeda Huda Fatima, Syeda Jazilah Faisal

“…Initiatives by NGOs like Pink Ribbon1 and Rehmat Medical Aid, such as free mobile mammography and diagnostic services, have successfully decreased costs, and corporate entities like Meezan Bank have programs to provide financial relief,5 yet rural awareness remains low. …”
Get full text

Breast screening participation and retention among immigrants and nonimmigrants in British Columbia: A population‐based study by Ryan R. Woods, Kimberlyn M. McGrail, Erich V. Kliewer, Arminee Kazanjian, Colin Mar, Lisa Kan, Janette Sam, John J. Spinelli

“…Abstract Breast cancer screening programs operate across Canada providing mammography to women in target age groups with the goal of reducing breast cancer mortality through early detection of tumors. …”
Get full text

Comparative pathogenesis of Ethiopia/Habru/2014 Lineage-IV peste des petits ruminants virus in goats and cattle by Fasil Aklilu, Hagos Ashenafi, Tesfu Kassa, Hassen Chaka, Demeke Sibhatu, Dereje Shegu, Abde Aliy Mohammed, Redeat Belaineh, Menbere Kidane, Hagos Asgedom, Tesfaye Chibssa, Getnet Mekonnen, Asegedetch Sirak, Solomon Gebredufe, Claudia Schulz, Catherine M. Herzog, Vivek Kapur

“…Results The results show that goats exhibited typical clinical signs 4 days post-inoculation, with seroconversion by day 6 and early detection of viral RNA in swabs and tissues by day 3 and virus isolation starting day 4. …”
Get full text

Epidemiology of inherited metabolic disorders in newborn screening: insights from three years of experience in Southern Iran by Leila Salarian, Homa Ilkhanipoor, Anis Amirhakimi, Zhila Afshar, Saman Nahid, Fariba Moradi Ardekani, Nazila Rahimi, Negar Yazdani, Abdolhossein Nikravesh, Zahra Beyzaei, Hossein Moravej

“…The Iranian Neonatal Screening Program piloted in Fars Province, screening nearly 100% of neonates for 20 disorders. …”
Get full text

Knowledge and Practice of Breast Self-examination among Middle-aged Females Attending a Tertiary Care Hospital by Barak Waris, Nauman Ismat Butt, Imania Khizar, Ihtisham UI Hasan, Ayman Bashir, Huzaifa Nadeem

“…Background: Breast self-examination (BSE) is a common self-performed screening method to detect any possible changes in the breast. It is widely practiced around the world in developed and underdeveloped countries for the earliest possible detection of breast cancer. …”
Get full text

Gynecological Malignancies in Albania: The Challenges of Cancer Care in a Low Resource Country by Kleida Mati, Carmelo Pozzo, Elona Cekani, Kleva Qeraj, Jona Prifti, Olti Pecini, Arlinda Elmasllari, Fatilba Skoku, Cesare Romagnolo

“…Recently, Albania has introduced a cervical cancer screening program along with HPV vaccination. Nonetheless, owing to lack of awareness and education about the disease and limited access to early screening programs, gynecological cancers are often detected at later stages. …”
Get full text

Global Epidemiology and Antimicrobial Resistance of Klebsiella Pneumoniae Carbapenemase (KPC)-Producing Gram-Negative Clinical Isolates: A Review by Matthew E. Falagas, Christina-Maria Asimotou, Maria Zidrou, Dimitrios S. Kontogiannis, Charalampos Filippou

“…Implementing proper infection control measures, antimicrobial stewardship programs, and enhanced surveillance is crucial.…”
Get full text

Exponential uptake of HPV self-collected cervical screening testing 2 years since universal availability in Victoria, Australia by Alvin Lee, David Hawkes, Daniel Sweeney, Kerryann Wyatt, Claire Nightingale, Corey Chalmers, Marion Saville

“…We also compared rates of HPV detection, invalid results, and time to colposcopy with practitioner-collected samples during the same period. …”
Get full text

Tooth morbidity and its impact on oral related quality of life in elderly tribal population-The Irula experience by Margret Beaula Alocious Sukumar, Roshni Mary Peter, Alex Joseph

“…Removing education and socioeconomic barriers, improving access to dental health care, and advocating culturally appropriate preventive programs could increase OHRQoL. Longitudinal study and policy-driven approaches should be carried out in future studies for sustainable health equity of the tribal population.…”
Get full text