Genotype-phenotype correlation in Brazillian Rett syndrome patients Correlação genótipo-fenótipo em pacientes brasileiras com síndrome de Rett by Fernanda T. de Lima, Decio Brunoni, José Salomão Schwartzman, Maria Cristina Pozzi, Fernando Kok, Yara Juliano, Lygia da Veiga Pereira

“…METHOD: Clinical evaluation of 105 patients, following a standard protocol. Detection of point mutations on the MECP2 gene was performed on peripheral blood DNA by sequencing the coding region of the gene. …”
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Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review by Francesca Salvatori, Saverio Siciliano, Francesco Maione, Dario Esposito, Stefania Masone, Marcello Persico, Giovanni D. De Palma

“…CLE has the potential to have an important role in management of IBD patients as it can be used to assess the grading of colitis and in detection of microscopic colitis in endoscopically silent segments. …”
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Prevalence of depression among medical students in Africa: Systematic review and meta-analysis. by Chilot Kassa Mekonnen, Hailemichael Kindie Abate, Zerko Wako Beko, Alebachew Ferede Zegeye, Abere Woretaw Azagew

“…Therefore, this result suggested that medical schools or Universities and concerned authorities better offer possible early detection and prevention programs as per the magnitude. …”
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Lessons Learned from the COVID-19 Pandemic: Simulation of the Tuberculosis Epidemic as a Function of Population Coverage with Screening by A. A. Starshinova, I. F. Dovgalyuk, N. N. Osipov, D. A. Kudlay

“…The findings demonstrate the need for mass screening of the population in the context of significant spread of tuberculosis infection for timely detection of patients with sputum smear-positive tuberculosis.…”
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Findings supporting neonatal screening for sickle cell disease: an observational study in Senegal by Lucie Petigas, Ndiogou Seck, Ndiogou Seck, Dominique Doupa, Dominique Doupa, Ibrahima Diagne, Ibrahima Diagne, Matthias Roth-Kleiner, Matthias Roth-Kleiner

“…IntroductionSickle cell disease (SCD) is a major contributor to morbidity and mortality in sub-Saharan Africa, and early detection through neonatal screening can improve outcomes. …”
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Lysophosphatidylethanolamine improves diastolic dysfunction by alleviating mitochondrial injury in the aging heart by Guiwen Xu, Wei Xiao, Pengqi Sun, Yuanjun Sun, Xinyu Yang, Xiaomeng Yin, Yang Liu

“…Mitochondrial morphologies from tissue samples were evaluated by transmission electron microscopy (TEM), while mitochondrial membrane potential and reactive oxygen species (ROS) levels were assessed using JC-1, MitoSOX, and DCFH-DA detection assays. We performed GO enrichment analysis between adult and aging mice and discovered significant enrichment in transcriptional programs associated with mitochondria and lipid metabolism. …”
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Improved Consistency of Lung Nodule Categorization in CT Scans with Heterogeneous Slice Thickness by Deep Learning-Based 3D Super-Resolution by Dongok Kim, Jae Hyung Park, Chang Hyun Lee, Young-Ju Kim, Jong Hyo Kim

“…<b>Background/Objectives</b>: Accurate volumetric assessment of lung nodules is an essential element of low-dose lung cancer screening programs. Current guidance recommends applying specific thresholds to measured nodule volume to make the following clinical decisions. …”
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Digital Health Approaches to Measles Surveillance in the Oltenia Region (January 2023 – June 2024) by Ana Maria BOLDEA, Alexandra ROTARU ZAVALEANU, Mircea SERBANESCU

“…Results: The implementation of digital surveillance and case monitoring systems allowed for the early detection of measles outbreaks and facilitated timely public health responses. …”
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The importance of using mobile ultrasound devices in improving the quality and safety of emergency care, anesthesia and intensive care by A. A. Krishtafor, D. A. Krishtafor, O. V. Kravets, O. V. Pylypenko

“…The authors point out that ultrasound is an important tool for monitoring the condition of patients with respiratory and heart failure, allowing for the prompt detection of pathological changes in the lungs and heart. …”
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Factors Associated with Baseline CD4 Cell Counts and Advanced HIV Disease among Male and Female HIV-Positive Patients in Iran: A Retrospective Cohort Study by Sima Afrashteh, Mohammad Fararouei, Haleh Ghaem, Mohammad Aryaie

“…Targeted HIV testing, implementation of screening programs for early detection, and access to care services to assure early ART are recommended to improve the clinical status and quality of life of the patients.…”
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LLM-Based Unknown Function Automated Modeling in Sensor-Driven Systems for Multi-Language Software Security Verification by Liangjun Deng, Qi Zhong, Jingcheng Song, Hang Lei, Wenjuan Li

“…With multi-language programs running on edge computing, embedded systems, and sensors, each connected device represents a potential attack vector, threatening data integrity and privacy. …”
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Awareness of colon cancer screening among the general population: Community-based study from the Qassim Region of Saudi Arabia by Mohammed D. Aldakhil, Abdullah S. Alayaaf, Nibras M. Alamro, Omar K. Aljubaili

“…Although a substantial proportion of participants demonstrated knowledge about the risk factors, symptoms, and prevention of CRC, there is limited knowledge about screening programs in the region. This underscores the need for public awareness campaigns and concerted efforts to eliminate the obstacles preventing more people from getting screened with colonoscopies for early detection and prevention of CRC.…”
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Effect of individual health perception, health consultation, and other risk factors on undiagnosed hypertension in South Africa by Muchiri E. Wandai, Brian E. Dixon

“…This underscores the need for health programs to emphasize the importance of regular blood pressure checkups. …”
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Serology for trachoma surveillance after cessation of mass drug administration. by Diana L Martin, Rhiannon Bid, Frank Sandi, E Brook Goodhew, Patrick A Massae, Augustin Lasway, Heiko Philippin, William Makupa, Sandra Molina, Martin J Holland, David C W Mabey, Chris Drakeley, Patrick J Lammie, Anthony W Solomon

“…Participants were examined for TF, had conjunctival swabs collected for nucleic acid amplification test (NAAT)-based detection of Ct, and blood collected for analysis of antibodies to the Ct antigens pgp3 and CT694 by multiplex bead-based immunoassay. …”
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Inclusion of non-medical interventions in model-based economic evaluations for tuberculosis: A scoping review. by Lauren C Ramsay, Marina Richardson, Rafael N Miranda, Marian Hassan, Sarah K Brode, Elizabeth Rea, Beate Sander

“…The majority of remaining evaluated medical interventions were focused on comparing various screening programs (e.g., immigrant screening program) and treatment regimens.…”
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Prevalence and predictors of carcinophobia among the non cancer population in Saudi Arabia by Raghib Abusaris, Dimah Alsaqabi, Alyaa F. A. Ibrahim, Ashraf A’aqoulah, Mona R. Alanazi, Manal Alsheikh, Fai Albawardi, Mohammed A. Awawdeh, Samah Saad Salem

“…Addressing psychological barriers such as carcinophobia is essential for promoting early detection and preventive healthcare behaviors. The findings suggest the need for culturally tailored cancer education and intervention programs to reduce fear and encourage proactive health management in Saudi Arabia.…”
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Early prediction of colorectal adenoma risk: leveraging large-language model for clinical electronic medical record data by Xiaoyu Yang, Jinjian Xu, Hong Ji, Jun Li, Bingqing Yang, Liye Wang

“…The proposed model demonstrates high predictive accuracy and has the potential to enhance early detection, making it well-suited for large-scale screening programs. …”
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A novel TRKB-activating internal tandem duplication characterizes a new mechanism of receptor tyrosine kinase activation by Lauren M. Brown, Gabor Tax, Pablo Acera Mateos, Antoine de Weck, Steve Foresto, Thomas Robertson, Fatimah Jalud, Pamela Ajuyah, Paulette Barahona, Jie Mao, M. Emmy M. Dolman, Marie Wong, Chelsea Mayoh, Mark J. Cowley, Loretta M. S. Lau, Teresa Sadras, Paul G. Ekert

“…Abstract Precision medicine programs like the Zero Childhood Cancer Program perform comprehensive molecular analysis of patient tumors, enabling detection of novel structural variants that may be cryptic to standard techniques. …”
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A temporal and spatial analysis of incidence and mortality of lip, oral cavity, and pharyngeal cancer in a Northeastern Brazilian state by Geovane Jesus de Almeida, Carolina Schmitz Tiezerin, Larissa Janinny Nunes Silva, Brenda Evelin Barreto da Silva, Alex Rodrigues Moura, Simone Soraia Silva Sardeiro, Carlos Anselmo Lima

“…Targeted interventions are critical, including equitable healthcare distribution, early detection programs, and lifestyle modifications to curb tobacco and alcohol use.…”
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Characterization of Bunch Compactness in a Diverse Collection of <i>Vitis vinifera</i> L. Genotypes Enriched in Table Grape Cultivars Reveals New Candidate Genes Associated with Be... by Marco Meneses, Claudia Muñoz-Espinoza, Sofía Reyes-Impellizzeri, Erika Salazar, Claudio Meneses, Katja Herzog, Patricio Hinrichsen

“…In summary, the utility of 3D automated phenotyping was validated for table grape backgrounds, and new SNPs and candidate genes associated with the BC trait were detected. The latter could eventually become a selection tool for grapevine breeding programs.…”
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