Optimization of serious bacterial infections intensive therapy in children in Anesthesiology and Intensive Care Department by M. Yu. Kurochkin, A. H. Davydova, Yu. V. Horodkova

“…Dynamic of medium molecular peptides was studied at admission, before discrete plasmapheresis and after it. Statistical data processing was performed using the Microsoft Excel software package. …”
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Transcriptomic, phenotypic and physiological analyses identify candidate regulators of Dendrobium stigma maturation and pollen-stigma interaction by Qian Wu, Shuxian Ren, Yuehong Ruan, Jiaxue Hu, Yin Li, Zongyan Li

“…O-GlcNAc glycosylation was detected in the stigma transcriptome for the first time, potentially linked to kinase activity and immune responses. …”
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NCBP2 predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis by Shichao Li, Yulan Wang, Xi Yang, Miao Li, Guoxiang Li, Qiangqiang Song, Junyu Liu

“…Background The cap-binding complex (CBC) plays a crucial role in facilitating gene expression by safeguarding mRNA from nonsense-mediated decay, promoting mRNA splicing, 3′-end processing, and facilitating nuclear export. Nevertheless, the precise biological functions and clinical implications of CBC in cancer remain ambiguous, necessitating further investigation for clarification. …”
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Screening and Characterization of Sialic Acid-Binding Variable Lymphocyte Receptors from Hagfish by Mark Rickard N. Angelia, Abigail Joy D. Rodelas-Angelia, Cheolung Yang, Sojeong Park, Seung pyo Jeong, Hyeok Jang, Dennis Berbulla Bela-ong, Hobin Jang, Kim D. Thompson, Taesung Jung

“…Given its role in infection and disease-related processes, sialic acid is a promising target for therapeutic approaches that utilize carbohydrate-binding molecules. …”
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Cardiac implications of chicken wooden breast myopathy by Thea Parsberg Støle, Andreas Romaine, Thea Kleiberg, Vibeke Høst, Marianne Lunde, Almira Hasic, Tiril Aurora Lintvedt, Karen Wahlstrøm Sanden, Svein O. Kolset, Jens Petter Wold, Addolorata Pisconti, Sissel Beate Rønning, Cathrine Rein Carlson, Mona Elisabeth Pedersen

“…Functional enrichment analysis of RNA sequencing also suggested a different molecular footprint of biological processes and pathways between the two groups.ConclusionHearts from wooden breast-affected chickens did not display the same fibrotic alterations as those previously found in the breast. …”
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Source apportionment of PM10 based on offline chemical speciation data at 24 European sites by Xiansheng Liu, Xun Zhang, Bowen Jin, Tao Wang, Siyuan Qian, Jin Zou, Vy Ngoc Thuy Dinh, Jean-Luc Jaffrezo, Gaëlle Uzu, Pamela Dominutti, Sophie Darfeuil, Olivier Favez, Sébastien Conil, Nicolas Marchand, Sonia Castillo, Jesús D. de la Rosa, Stuart Grange, Christoph Hueglin, Konstantinos Eleftheriadis, Evangelia Diapouli, Manousos-Ioannis Manousakas, Maria Gini, Silvia Nava, Giulia Calzolai, Célia Alves, Marta Monge, Cristina Reche, Roy M. Harrison, Philip K. Hopke, Andrés Alastuey, Xavier Querol

“…Biomass burning was detected at 23 sites, contributing 8% to 41% on yearly averages, with substantial increase in winter. …”
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Microbial Food Safety Risk to Humans Associated with Poultry Feed: The Role of Irradiation by Tahiru Mahami, Wellington Togby-Tetteh, Delali Isaac Kottoh, Leticia Amoakoah-Twum, Emmanuel Gasu, Sylvester Nana Yao Annan, Daniel Larbi, Isaac Adjei, Abraham Adu-Gyamfi

“…The most effective antibiotic against Gram negative bacteria (Enterobacter cloacae and Klebsiella pneumoniae) was gentamicin while cotrimoxazole was the most effective against Bacillus cereus (Gram positive). Radiation processing of 5kGy totally eliminated all microbes including MDR food borne pathogens. …”
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YY1 induced USP13 transcriptional activation drives the malignant progression of hepatocellular carcinoma by deubiquitinating WWP1 by Qingwei Zhu, Zibo Yuan, Qiang Huo, Qiliang Lu, Qingsong Wu, Junwei Guo, Wen Fu, Ying Lu, Lei Zhong, Wenzhong Shang, Di Cui, Shuangshuang Li, Xin Liu, Kangsheng Tu, Dongsheng Huang, Qiuran Xu, Xiaoge Hu

“…Ubiquitin-specific protease 13 (USP13) is a deubiquitinating enzyme (DUB) that is involved in many cellular processes. However, the mechanism by which USP13 regulates deubiquitination remains largely unknown. …”
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Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach by Christian Ayala-Ortiz, Moira Hough, Elizabeth K. Eder, David W. Hoyt, Rosalie K. Chu, Jason Toyoda, Steven J. Blazewicz, Patrick M. Crill, Ruth Varner, Scott R. Saleska, Virginia I. Rich, Virginia I. Rich, Malak M. Tfaily, Malak M. Tfaily

“…Our findings demonstrate how technological advancements in analytical tools can provide a more detailed view of carbon cycling processes in complex soil systems.…”
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Magnetite drives microbial community restructuring and stimulates aceticlastic methanogenesis of type II Methanosarcina in mangrove sediments by Jinjie Zhou, Cui-Jing Zhang, Dayu Zou, Chengxiang Gu, Meng Li

“…Abstract Background Mangrove wetlands are critical hotspots of methane emissions, yet the role of naturally occurring minerals in shaping their microbial communities and methanogenic processes is poorly understood. Magnetite, a common iron mineral in soils and sediments, has been reported to enhance aceticlastic methanogenesis and facilitate syntrophic methanogenesis. …”
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YEATS2 promotes malignant phenotypes of esophageal squamous cell carcinoma via H3K27ac activated-IL6ST by Yuanfang Zhai, Yuanfang Zhai, Fanyu Zhang, Fanyu Zhang, Xiaoyu Shi, Xiaoyu Shi, Siwei Zou, Siwei Zou, Xiaoling Hu, Xiaoling Hu, Chengyuan Shan, Chengyuan Shan, Ling Zhang, Binbin Zou, Xin Yang, Pengzhou Kong, Xiaolong Cheng

“…IntroductionHistone acetylation modifications can regulate gene transcription and play crucial roles in multiple tumorigeneses processes. YEATS domain proteins are one important type of acetylation readers. …”
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Eurycomalactone switched hepatocellular carcinoma cells into quiescence through 5’tRFAla/DVL/β-catenin pathway inhibition by Zhipeng Zhang, Yanmei Wu, Wenqiang Liang, Zhifang Liao, Hongbo Liao, Xingxing Xing, Wenxin Yi, Zixuan Liu, Yicheng Li, Mengya Shi, Dongling Lin, Ting Gu, Biao Wu, Mingzhi Zou, Huilai Miao, Xin Wu

“…Abstract Although tsRNA has been demonstrated to modulate various physiological processes analogous to miRNA, the potential regulatory functions and mechanisms of tsRNAs related to the pharmacological effects of small molecule drugs remain unclear. …”
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<i>Commiphora leptophloeos</i> Bark Decoction: Phytochemical Composition, Antioxidant Capacity, and Non-Genotoxic Safety Profile by José Rafael da Silva Araujo, Rafael de Felício, Camila Marinho da Silva, Palloma Lima de Oliveira, Silvany de Sousa Araújo, Laís Roberta Deroldo Sommaggio, Adriana Fabiana Corrêa da Silva, Paulo Henrique Valença Nunes, Bruno Oliveira de Veras, Erwelly Barros de Oliveira, Jaciana dos Santos Aguiar, Maria Aparecida Marin-Morales, Daniela Barretto Barbosa Trivella, Ana Maria Benko-Iseppon, Márcia Vanusa da Silva, Ana Christina Brasileiro-Vidal

“…Phytochemical characterization was conducted using ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS), and data were processed using the NP³ MS Workflow 1.1.4 software, allowing for the annotation of key secondary metabolites. …”
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Emulgel Containing Metronidazole and Clindamycin for the Treatment of Rosacea by Guillermo De Grau-Bassal, Ana Cristina Calpena-Campmany, Marcelle Silva-Abreu, Joaquim Suñer-Carbó, Mireia Mallandrich-Miret, Sergio Martínez-Ruiz, Cecilia Cordero, Alfonso Del Pozo, Núria Bozal-de Febrer

“…Release and permeation data revealed sustained drug release and adequate permeation through human skin. Non-toxicity was detected and the MD showed an anti-inflammatory effect with non-interference of CM. …”
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Construction of RNA m6A profiles in liver tissue of mice in sepsis-induced liver injury based on m6A MeRIP-seq and RNA-seq by Li Li, Penghui Li, Yuhua He, Ziyi Xu, Yitao Fan, Xueying Jia, Yingru Liu, Lijie Qin

“…N6-methyladenosine (m6A) modification plays a significant role in the pathological processes of SILI, but its specific mechanisms remain unclear and require further elucidation. …”
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Novel long noncoding lncARF mediated hyperhomocysteinemia-induced atherosclerosis via autophagy inhibition in foam cells by Ning Ding, Shengchao Ma, Qingning Chang, Lin Xie, Guizhong Li, Yinju Hao, Jiantuan Xiong, Anning Yang, Xiaoling Yang, Yideng Jiang, Huiping Zhang

“…Long non-coding RNAs (lncRNAs) are emerging regulators of pathophysiological processes including atherosclerosis, while the underlying mechanisms of its involvement in Hcy induced-atherosclerosis remain largely unknown. …”
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Safety of a Medicinal Product Based on Human Glial Progenitor Cells: A Pilot Study of Retrobulbar Administration in C57BL/6J Mice by V. O. Nebogatikov, D. I. Salikhova, E. V. Belousova, E. V. Bronovitsky, E. A. Orlova, M. A. Lapshina, D. V. Goldshtein, A. A. Ustyugov

“…There were no significant differences in neuroinflammatory markers between the groups receiving GPCs at different doses, except for an increase in astrocyte activation at a dose of 150×103 cells/mouse, which could potentially indicate inflammatory processes in the brain. The study detected no pathological changes in the brain or cell damage markers in the blood of mice after retrobulbar GPC injections of 15×103 or 50×103 cells/mouse.CONCLUSIONS. …”
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Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue by Carol Costa Encarnação, Carolinne Souza Amorim, Victor Aguiar Franco, Luiz Gabriel Xavier Botelho, Ronan Christian Machado dos Santos, Isadora Ramos-Andrade, Luiz Guilherme Kraemer-Aguiar, Christina Barja-Fidalgo, João Alfredo Moraes, Mariana Renovato-Martins

“…Elevated leptin levels are detected in the circulation and in extracellular vesicles (EVs) released by adipose tissue, particularly in cases of obesity. …”
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TO JUSTIFY A DIFFERENTIATED APPROACH TO PRESERVATION OF THIRD MOLARS DURING ORTHODONTIC TREATMENT BY DETERMINING THEIR CONDITION AND POSITION IN THE JAW by S.І. Doroshenko, I.S. Kuzmenko, K.V. Storozhenko, S.V. Irkha, Kh.M. Demianchuk

“…Measurement data were processed using mathematical statistics. The mean and the confidence interval for the data sample were calculated according to GOST R 8.736 – 2011. …”
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COMPARATIVE CHARACTERISTICS OF THE EFFECTIVENESS OF DIRECT AND INDIRECT RESTORATIONS ON TEETH WITH DISCOLORATION by I.V. Zhyvotovskyi, Yu.I. Sylenko, M.V. Khrebor

“…The obtained results were processed by the method of variational statistics using Student's test. …”
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