Knowledge, attitude, practice towards COVID-19 pandemic and its prevalence among hospital visitors at Ataye district hospital, Northeast Ethiopia. by Daniel Gebretsadik, Nuru Ahmed, Edosa Kebede, Saba Gebremicheal, Melaku Ashagrie Belete, Metadel Adane

“…Oro-pharyngeal specimen was collected by trained healthcare provider and processed in a molecular laboratory. After extraction of viral nucleic acid, the Real-time fluorescent polymerase chain reaction (RT-PCR) kit was used for detecting novel coronavirus (2019-nCoV). …”
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Human papillomavirus in vulvar cancer: a systematic review by D. S. Dolgasheva, M. K. Ibragimova, E. A. Kravtsova, I. A. Tsydenova, K. A. Gaptulbarova, M. M. Tsyganov, N. V. Litviakov

“…In recent decades, a rise in incidence of vulvar cancer developed after preceding degenerative processes was noted. A relationship between human papillomavirus and cervical cancer has long been known and confirmed, so an issue regarding a potential relation between the etiology of vulvar cancer and of HPV remains relevant. …”
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Topology-aware pathway analysis of spatial transcriptomics by Siras Hakobyan, Maria Schmidt, Hans Binder, Arsen Arakelyan

“…This suggests that branch-level pathway activities can themselves drive clustering and pinpoint spatially deregulated processes. To assess cluster-specific functional annotation, we compared PSF results to conventional ORA (based on marker genes) and GSDensity (based on cluster-specific gene sets). …”
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Understanding Human Papillomavirus Vaccination Hesitancy in Japan Using Social Media: Content Analysis by Junyu Liu, Qian Niu, Momoko Nagai-Tanima, Tomoki Aoyama

“…MethodsWe collected tweets related to the HPV vaccine from 2011 to 2021. Natural language processing techniques and large language models (LLMs) were used for stance analysis of the collected data. …”
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Effect of Seminal Plasma on the Freezability of Boar Sperm by Kuanfeng Zhu, Yukun Song, Zhi He, Peng Wang, Xuguang Wang, Guoshi Liu

“…These DEMs were related to energy metabolism, drugs, or environmental pollutants, while the DEPs were mainly involved in the cytoskeletal dynamics and cell adhesion processes. There were 33 metabolites and 70 proteins significantly associated with mean progress motility (PM) at 10 min and 2 h after thawing. …”
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Investigation of heavy metals adsorbed on microplastics in drinking water and water resources of Zabol by Mohammad Reza Rezaei Kahkha, Jamshid Piri, Ali Faghihi-Zarandi, Massoud Kaykhaii

“…This novel research emphasizes the impact of secondary pollution and water treatment processes on MP fragmentation and HM contamination. …”
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Phosphorylation of Bok at Ser-8 blocks its ability to suppress IP3R-mediated calcium mobilization by Caden G. Bonzerato, Katherine R. Keller, Richard J. H. Wojcikiewicz

“…It is clear, however, that Bok binds strongly to inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs), which govern the mobilization of Ca2+ from the endoplasmic reticulum, a signaling pathway required for many cellular processes. Also known is that Bok has a highly conserved phosphorylation site for cAMP-dependent protein kinase at serine-8 (Ser-8). …”
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Platelet secretions exert anti-inflammatory effects in vitro on neutrophils and uterine epithelia in cattle: a possible role in amplifying the uterine immune network toward pregnan... by Mohamed Samy Yousef, Mohamed Samy Yousef, Ihshan Akthar, Dongxue Ma, Shingo Haneda, Kazuya Kusama, Masayuki Shimada, Kazuhiko Imakawa, Akio Miyamoto

“…Real-time PCR was performed to detect the expression of targeted genes (cytokines), including TNFA, IL1B and PGES1. …”
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Spatial relationships between macrophyte assemblages, water and sediment features in deep lakes by Alice Dalla Vecchia, Rossano Bolpagni, Alex Laini, Daniele Nizzoli, Mariano Bresciani, Mattia Martin Azzella, Martin Wilkes

“…Conversely, no strong spatial structure was detected at the microscale (i.e., with metric resolution, comparing the different study plots with each other). …”
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GluR2 overexpression in ACC glutamatergic neurons alleviates cancer-induced bone pain in rats by Futing Ba, Jinrong Wei, Qi-Yan Feng, Chen-Yang Yu, Meng-Xue Song, Shufen Hu, Guang-Yin Xu, Hai-Long Zhang, Guo-Qin Jiang

“…The anterior cingulate cortex (ACC) plays a critical role in processing and modulating chronic pain. This study investigates how the GluR2 receptors (calcium impermeable AMPA receptors) in ACC glutamatergic neurons regulate CIBP. …”
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Impact of PEGylation and hyaluronan functionalization on lipoplex-mediated mRNA delivery to the canine retina by Tatyana Appelbaum, David A. Smith, Kei Takahashi, Jennifer C. Kwok, Hannah Sorenson, William A. Beltran

“…The data suggest that transfection efficiency in retinal cells is influenced by both intracellular processing of mRNA lipoplexes and their uptake, with the former playing a predominant role.…”
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Gastrodin Mitigates Ketamine-Induced Inhibition of F-Actin Remodeling and Cell Migration by Regulating the Rho Signaling Pathway by Ping-Cheng Shih, I-Shiang Tzeng, Yi-Chyan Chen, Mao-Liang Chen

“…<b>Background/Objects</b>: Rho signaling plays a role in calcium-regulated cytoskeletal reorganization and cell movement, processes linked to neuronal function and cancer metastasis. …”
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Profiling of Circulating Cell-free DNA Methylation Patterns Identifies Aberrant Methylated CTBP1 Promotor Sites for Prediction of Alzheimer’s Disease by Zhiwu Dong, Kewen Zhao, Hongjun Gu, Wenwei Yang, Xin Zhang

“…Functional annotation and pathway enrichment analysis underscored processes and pathways inherent in the nervous system. …”
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Study on Enzyme Activity and Metabolomics during Culture of Liquid Spawn of <i>Floccularia luteovirens</i> by Yanqing Ni, Qiuhong Liao, Siyuan Gou, Tongjia Shi, Wensheng Li, Rencai Feng, Zhiqiang Zhao, Xu Zhao

“…To comprehensively investigate the physiological characteristics and metabolic processes of the mycelium of <i>Floccularia luteovirens</i> (<i>F. luteovirens</i>), a wild edible fungus unique to the plateau region, we conducted an in-depth analysis of the mycelium enzyme activity and metabolites during different culture periods. …”
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Longitudinal evidence for a mutually reinforcing relationship between white matter hyperintensities and cortical thickness in cognitively unimpaired older adults by Jose Bernal, Inga Menze, Renat Yakupov, Oliver Peters, Julian Hellmann-Regen, Silka Dawn Freiesleben, Josef Priller, Eike Jakob Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Björn H. Schott, Frank Jessen, Ayda Rostamzadeh, Wenzel Glanz, Enise I. Incesoy, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Christoph Laske, Sebastian Sodenkamp, Annika Spottke, Anna Esser, Falk Lüsebrink, Peter Dechent, Stefan Hetzer, Klaus Scheffler, Stefanie Schreiber, Emrah Düzel, Gabriel Ziegler

“…Conclusions Our study suggests that cortical thinning and WMH progression could be mutually reinforcing rather than parallel, unrelated processes, which become entangled before cognitive deficits are detectable. …”
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Discovery of a Pair of Galaxies with Both Hosting X-Ray Binary Candidates at z = 2.544 by Sijia Cai, Zheng Cai, Jianwei Lyu, Yunjing Wu, Xiaojing Lin, Mingyu Li, Junjie Mao, Jiayi Chen, Pengjun Lu

“…This galaxy pair represents the highest redshift non-AGN-dominated galaxies with individual X-ray detections reported to date. This finding suggests that the contribution of XRBs to galaxy X-ray emission at high redshift may be underestimated.…”
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Hybrid deep learning enables multi-institutional delineation of active bone marrow for gynecologic radiotherapy by Zhe Zhang, Xiao Lu, Sicheng He, Tao Huang, Shaobin Wang, Mingjun Lu, Xiaomin Zhang, Zhibo Tan, John Moraros, Lei Zhang, Xin Li, Zhan Li, Zihao Deng, Yimeng Zhang, Mengjie Dong, Shuihua Wang, Yajie Liu

“…Using 18F-FDG PET/CT as a reference, we developed a deep learning method to detect hematopoietic active bone marrow (ABM) on CT in gynecologic cancer patients and assess clinical benefits. …”
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Association Between the Effectiveness and Magnitude of Foot Microcirculation Assessed by Radionuclide Angiography and One Year Limb Outcomes in Patients with Chronic Limb Threateni... by Takuya Hashimoto, Yoshitaka Kumakura, Kenichi Ichikawa, Satoshi Yamamoto, Takashi Endo, Masaya Sano, Osamu Sato, Juno Deguchi

“…Novel parameters (pedal transit time and peak pedal count) were derived by processing the time–activity curves of the detected tracers in each region of interest in the limbs. …”
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Pre-Hospital Point-of-Care Troponin: Is It Possible to Anticipate the Diagnosis? A Preliminary Report by Cristian Lazzari, Sara Montemerani, Cosimo Fabrizi, Cecilia Sacchi, Antoine Belperio, Marilena Fantacci, Giovanni Sbrana, Agostino Ognibene, Maurizio Zanobetti, Simone Nocentini

“…<b>Results</b>: The Atellica VTLi demonstrated reasonable sensitivity for detecting AMI, with sensitivity increasing from 60% at the first measurement (time 0) to 80% at the second measurement (time 1 h). …”
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Pyropheophorbide-α methyl ester-mediated photodynamic therapy triggers pyroptosis in osteosarcoma cells via the ROS/caspase-3/GSDME pathway by Qiu Huang, Yong Tao, Ye Zhang, Yuxing Chen, Fuqiang Tan, Yunsheng Ou

“…Cell viability and apoptosis ratio were detected using CCK-8 and Annexin V–Propidium Iodide staining, respectively. …”
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