Autophagy- and oxidative stress-related protein deregulation mediated by extracellular vesicles of human MJD/SCA3 iPSC-derived neuroepithelial stem cells and differentiated neural... by Liliana S. Mendonça, Ricardo Moreira, Daniel Henriques, Mónica Zuzarte, Teresa M. Ribeiro-Rodrigues, Henrique Girão, Luís Pereira de Almeida

“…Abstract Extracellular vesicles (EVs) have been associated with the transport of molecules related to the pathological processes in neurodegenerative diseases. Machado-Joseph disease (MJD) is a neurodegenerative disorder triggered by mutant ataxin-3 protein that causes protein misfolding and aggregation resulting in neuronal death. …”
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Advancing Mental Health Care: A Comprehensive Review of Digital Tools and Technologies for Enhancing Diagnosis, Treatment, and Wellness by Muhammad Khalid Anser, Agha Amad Nabi, Ishfaq Ahmad, Muhammad Moinuddin Qazi Abro, Khalid Zaman

“…Chatbots employ machine learning algorithms and natural language processing to deliver customized support and show promise for quick intervention. …”
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Analysis of ANRIL gene polymorphism rs4977574 association with kidney cancer development in Ukrainian population. by A. D. Volkogon, V. Yu. Harbuzova, A. V. Ataman

“…The mathematical data were processed using the SPSS software package (version 17.0). …”
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Identification of Exosome-Associated Biomarkers in Diabetic Foot Ulcers: A Bioinformatics Analysis and Experimental Validation by Tianbo Li, Lei Gao, Jiangning Wang

“…A sum of 7901 differentially expressed genes (DEGs) of DFUs were detected and intersected with 125 literature-curated exosome-related genes (ERGs) to yield 51 candidates. …”
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Interleukin-37 Suppresses the Function of Type 2 Follicular Helper T in Allergic Rhinitis by Xi Luo, Yanhui Wen, Xiangqian Qiu, Lifeng Zhou, Qingxiang Zeng, Wenlong Liu

“…Interleukin-37 (IL-37) has emerged as an intrinsic modulator of innate immunity and inflammatory processes. We aimed to investigate the regulatory effect of IL-37 on Tfh2 cells in the pathogenesis of AR. …”
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Artificial intelligence for difficult airway assessment: a protocol for a systematic review with meta-analysis by Dan Liu, Tingting Li, Li Du, Jianqiao Zheng, Yujie Huang, Weiyi Zhang

“…Artificial intelligence (AI) is a rapidly evolving science with greater data processing ability than humans. AI, given its ever-expanding applications in medical diagnosis and disease prediction, has been employed to predict cases with difficult airways. …”
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Protective Effect of Broken Pine Pollen on Cadmium-poisoned Rats by Yan XING, Shuai SHAO, Xiaoxian HE, Shuhui SONG, Limei ZHANG

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Experimental evolution of plant rhizobacteria reveals emerging adaptive mutations by Jiahui Li, Yingying Zhang, Wenjun Jiang, Li-Qun Zhang

“…ABSTRACT The colonization capability of plant growth-promoting rhizobacteria (PGPRs) in the rhizosphere is essential for their beneficial effects on plant growth, yet the evolutionary processes and adaptive potential of PGPRs in this environment remain underexplored. …”
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Mitochondrial genome analysis of the endangered Oreocharis esquirolii: insights into evolutionary adaptation and conservation by Lang Chen, Rong-Rong Yan, Chong-Yi Yang, Li-Zhen Ling, Xin-Xiang Bai, Qi-Fei Ren, Guo-Xiong Hu

“…Positive selection signals were detected in seven coding genes of the O. esquirolii mitogenome, with a potential impact on environmental adaptation. …”
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Analysis of Evolution Structure of a Squall Line in Zhejiang Province Based on Multi-band Radar Observation by QIAN Zhuolei, YAN Peiwen, LI Feng, HUANG Ying

“…The observation of the S-band dual polarisation radar showed that the evolution of squall lines went through processes such as initiation, merging, growth, maturity, and disappearance. …”
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Cytopathological characteristics for provoked lesions of squamous epithelia of digestive system in animal models by V. G. Shestakova, L. I. Nigmatullina, I. B. Atadzhanov, S. A. Donskov, Yu. V. Kozlovskaya, I. S. Dolgopolov, M. Yu. Rykov

“…This model of provocation of carcinogenesis will be used in the next study of neoplastic processes of the female reproductive system.…”
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Digital Technology of Assesment the Power Capacity of Tractor Fleet of an Agricultural Enterprise by V. V. Alt, O. F. Savchenko, O. V. Elkin

“…The authors have shown a possibility of reducing costs required to maintain the detected power deviations due to excessive fuel consumption through timely repair and adjustment-and-control actions. …”
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Vitamin C, Sugar Content, Color Intensity and Some Physicochemical Properties of Watermelon and Orange Peels by Selvican Gökçe, İsa Arslan Karakütük, Memnune Şengül

“…Objective: Peels generated as waste during the consumption and processing of fruits and vegetables contribute to both nutritional losses and environmental pollution. …”
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Microplastics in <i>Cronius ruber</i>: Links to Wastewater Discharges by Sofía Huelbes, May Gómez, Ico Martínez, Raül Triay-Portella, Miguel González-Pleiter, Alicia Herrera

“…Rayon, commonly used in textiles, was the most frequently identified polymer (52%), highlighting the role of wastewater from laundry processes as a significant pollution source. Beaches close to unauthorized wastewater discharges, such as Anfi del Mar (<i>n</i> = 3) and El Puertillo (<i>n</i> = 32), showed the highest contamination levels, with a frequency of occurrence (FO) of microplastic particles of 67% and 58%, respectively. …”
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Transcriptome-wide dynamics of m6A methylation in ISKNV and Siniperca chuatsi cells infected with ISKNV by Qijin Miao, Jing Jiang, Siyou Huang, Jie Gao, Qingqing Liu, Rui Zheng, Yiling Kang, Changjun Guo, Jianguo He, Junfeng Xie

“…Gene enrichment analysis revealed that m6A-related genes were enriched in biological processes and pathways such as gene expression, cellular structure, immune responses, and cell death. …”
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Decoding volatile-microbial-physicochemical interplay of sensory preference in commercial shrimp paste based on flavoromics and high-throughput sequencing by Mengyue Hu, Ling Zhao, Huihui Sun, Qi Liu, Yong Xue, Rong Cao

“…Comprehensive volatile profiling using GC-IMS and GC-MS detected 44 and 40 volatiles, respectively, with 30 identified as aroma-active compounds (odor-active value ≥ 1). …”
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An Integrated Approach to Develop Innovative, Sustainable, and Effective Cosmetic Ingredients: The Case Report of Fatty-Acids-Enriched Wild Strawberry Waste Extract by Marta Faggian, Silvia Lucchetti, Sara Ferrari, Gabriele De Nadai, Stefano Francescato, Giovanni Baratto, Nicola De Zordi, Silvia-Maria Stanic, Gregorio Peron, Stefania Sut, Alessandra Semenzato, Stefano Dall’Acqua

“…As case report, a supercritical CO₂ extract obtained from wild-strawberry-processing waste after jam production (WSWSCO₂ extract) was developed. …”
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A Short-lived Rejuvenation during the Decades-long Changing-look Transition in the Nucleus of Mrk 1018 by Kai-Xing Lu, Yan-Rong Li, Qingwen Wu, Luis C. Ho, Zhi-Xiang Zhang, Hai-Cheng Feng, Sha-Sha Li, Yong-Jie Chen, Mouyuan Sun, Xinwen Shu, Wei-Jian Guo, Cheng Cheng, Jian-Guo Wang, Dongchan Kim, Jian-Min Wang, Jin-Ming Bai

“…Changing-look active galactic nuclei (CL-AGNs), characterized by the emergence or disappearance of broad lines accompanied by extreme continuum flux variability, have drawn much attention for their potential to reveal physical processes underlying AGN evolution. We perform seven-season spectroscopic monitoring on Mrk1018, one of the earliest identified CL-AGN. …”
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Genome-wide identification and association analysis of informative SNPs of various nutri-nutraceutical traits in Buckwheat (Fagopyrum spp.) by Madhiya Manzoor, Jebi Sudan, Adil Nath, Basharat Bhat, Parvaze A. Sofi, M. Ashraf Bhat, P. V. Vara Prasad, Sajad Majeed Zargar

“…Gene Ontology analysis highlighted key biological processes, including lipid transport, tryptophan metabolism, and protein phosphorylation, providing insights into the molecular mechanisms governing these traits. …”
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Phenolic and Iridoid Glycosides from <i>Leonurus cardiaca</i> L. and Their Effects on the α, δ, and γ Subtypes of the PPAR System—Including the Discovery of the Novel Phenylethanoi... by Kenny Kuchta, Nobuyasu Matsuura, Tung Huu Nguyen, Christian Rusch, Munekazu Iinuma, Yukihiro Shoyama, Hans Wilhelm Rauwald

“…For the PPARδ experiment, all nineteen isolated constituents and GW0742 (positive control) were added to the medium of transfected COS-1 cells and further processed according to a standardized luciferase assay protocol. …”
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