Chemotherapy-free combination of ibrutinib and obinutuzumab for untreated advanced follicular lymphoma: results of a phase II study from the German Lymphoma Alliance by Christian Schmidt, Gabriel Scheubeck, Vindi Jurinovic, Martin Sökler, Roswitha Forstpointner, Christian Buske, Andreas Viardot, Ulrich Keller, Ullrich Graeven, Reinhard Marks, Mathias Hänel, Rüdiger Liersch, Jan Dürig, Christiane Pott, Eva Hoster, Michael Unterhalt, Wolfgang Hiddemann

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Evolution of Innovative Surgical Techniques Using the Example of Selective Splenorenal Anastomosis Surgery by A. Yu. Anisimov, F. B. Mavlonov, D. E. Erkinova, A. I. Andreev, R. A. Ibragimov, E. Yu. Mandryka

“…No thrombosis of vascular conduits was detected in the early postoperative period according to Doppler ultrasound data. …”
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Impact of Population-Based Screening for Diabetes and Prediabetes Among 67-Year-Olds Using Point-of-Care HbA1c on Healthcare Ultilisation, Results from the VISP Cohort by Andersen JW, Høgh A, Lindholt JS, Søgaard R, Støvring H, Yderstræde KB, Sandbæk A, Dahl M

“…Despite expectations, healthcare utilization did not decrease among those with normal HbA1c levels.Conclusion: Population-based screening for DM and CVD among 67-year-olds resulted in increased healthcare utilization, particularly among those with screen-detected DM and pre-DM. The anticipated reduction in healthcare utilization among individuals with normal HbA1c levels was not observed. …”
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Possibilities and reserves of using electronic medical records data in health information systems on the example of assessing the causes of visits to outpatient clinics and death i... by I. V. Samorodskaya, R. N. Shepel, I. V. Klyuchnikov, M. M. Lukyanov, S. Yu. Martsevich, E. P. Kakorina, O. M. Drapkina

“…Statistical analysis was performed using the SPSS-26.0 program.Results. The mean age at death in group 2 was significantly higher than in groups 1, 3 and 4 (p<0,001). …”
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Effect of oxalic acid on Ca²⁺ concentration and signaling pathways in plants by Li Yang, Zhao Yuan, Xu Youping, Wang Jipeng, Cai Xinzhong

“…The known roles of OA in pathogenicity include lowering extracellular pH value and thus increasing activity of CWDEs, altering redox status to regulate accumulation of reactive oxygen species (ROS) and programmed cell death (PCD), and having direct toxicity to plant cells. …”
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Quantitative Proteomic Study Reveals Amygdalin Alleviates Liver Fibrosis Through Inhibiting mTOR/PDCD4/JNK Pathway in Hepatic Stellate Cells by Huang H, Ru SJ, Chen JM, Liu W, Fang SH, Liu Q, Meng Q, Liu P, Zhou H

“…The mRNA and protein levels of related molecules were detected by RT-qPCR and Western blotting, respectively.Results: Amygdalin could effectively ameliorated CCl4-induced liver fibrosis in mice. …”
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Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes by Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono

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Gingerols and Shogaols of Zingiber officinale var. sunti Valeton as Potential Allosteric Agonists of Human GABAA Receptor by in silico Pharmacology Approach by Kuswandani F, Wilar G, Wahyuni IS, Megantara S, Pitaloka DAE, Levita J, Jiranusornkul S

“…The UPLC analysis was performed to detect and quantify gingerol and shogaol in EEZO.Results: The best pre-ADMET prediction was shown by 6-gingerol, whereas the molecular docking simulations revealed that the best binding affinity and stability were shown by 6-gingerol (− 7.41 kcal/mol) and 10-shogaol (− 8.24 kcal/mol), which are comparable to that of diazepam. …”
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LH Gene Cloning, Sequence Feature Analysis and Prokaryotic Expression in Conger myriaster by Yan CHEN, Bao SHI, Chenggang WANG, Wanjun BO, Kewen YAN, Meijun TAO, Xinyu ZHAO, Xiaodong MA

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Validation of Replicable Pipeline 3D Surface Reconstruction for Patient-Specific Abdominal Aortic Lumen Diagnostics by Edoardo Ugolini, Giorgio La Civita, Moad Al Aidroos, Samuele Salti, Giuseppe Lisanti, Emanuele Ghedini, Gianluca Faggioli, Mauro Gargiulo, Giovanni Rossi

“…The 3D surface reconstruction demonstrated reliability, low processing times, and clinically valid reconstructions. …”
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Phage DisCo: targeted discovery of bacteriophages by co-culture by Eleanor A. Rand, Natalia Quinones-Olvera, Kesther D. C. Jean, Carmen Hernandez-Perez, Siân V. Owen, Michael Baym

“…This approach allows rapid exploration of the diversity within phage samples with vastly streamlined processes, and we anticipate it will be widely adopted within the phage discovery field.…”
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Extra-aural disorders in patients with acoustic trauma who were in the zone of the antiterrorist operation. by T. A. Shidlovs’ka, L. G. Petruk

“…Diencephalic structures irritation was detected in 54,2%, stem-diencephalic - in 30,5% of cases. …”
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GENDER DISTINCTIONS OF MICROALBUMINURIA AND ITS RELATION TO INTRARENAL HEMODYNAMIC AND LEPTIN LEVEL IN ARTERIAL HYPERTENSION by V. I. Podzolkov, A. E. Bragina, J. N. Rodionova

“…Leptin serum level was determined\ by radioimmunoassay. MAU was detected by semiquantitative test. Results were processed with SPSS-11.0 software package. …”
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Methodology for the identification of bioactive and marker peptides in the organs of cattle and pigs by D. V. Khvostov, N. L. Vostrikova, I. M. Chernukha

“…The marker peptides were detected by a triple quadrupole mass spectrometer (Agilent 6410 Triple Quadrupole LC/MS). …”
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Authentication of vegetable oils using isotope mass spectrometry by A. L. Panasyuk, D. A. Sviridov, A. A. Shilkin

“…Both the  physiological value of the  product and its cost largely  depend on the  type of processed raw materials. In this  regard, the  establishment of the  type of vegetable raw materials used for the production of vegetable oils is an important area of research in the identification of this product type. …”
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A multistage Plasmodium CRL4WIG1 ubiquitin ligase is critical for the formation of functional microtubule organization centers in microgametocytes by Ravish Rashpa, Cameron Smith, Katerina Artavanis-Tsakonas, Mathieu Brochet

“…Protein ubiquitination by E3 ligases is a critical post-translational modification required for various cellular processes during the lifecycle of Plasmodium parasites. …”
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Spatiotemporal assessment of environmental change in Kushtia, Bangladesh (1998–2023) using remote sensing-based environmental indices by Md. Anik Hossain, Md. Rahedul Islam, Tamanna Yesmin, Rabeya Sultana, Md. Kamrul Hossain, Rafiquel Islam

“…Satellite images were processed in ENVI 5.3 and analyzed in ArcGIS 10.8, while PCA determined the weights of the indices. …”
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TERT promoter methylation predicts overall survival, immune cell infiltration and response to immunotherapy in clear cell renal cell carcinoma by Xinyu Guan, Jiahao Meng, Wenjun Yi, Kun Ye, Hongyu Gao, Yue Hong, Limeng Qu, Shirong Ding, Qian Long

“…Despite its canonical role in maintaining telomere length in cancer cells, TERT is also involved in various oncogenic processes independent of its enzymatic activity. However, the role of TERT in the tumor immune microenvironment has been largely unexplored. …”
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Adequate post-ischemic reperfusion of the mouse brain requires endothelial NFAT5 by Reiner Kunze, Paul Wacker, Paula Breuer, Emil Nasyrov, Ivan M. Kur, Andreas Weigert, Andreas H. Wagner, Hugo H. Marti, Thomas Korff

“…In contrast, MCAO-induced edema formation, inflammatory processes and angiogenesis were not altered in Nfat5 (EC)−/− mice. …”
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Clinical characteristics of postmenopausal women with endometrial polyps by E. G. Kobaidze, Y. N. Matveeva, E. V. Shirinkina, N. V. Statnykh, N. M. Pirozhnikova

“…The study results showed a statistically significant relationship between the endometrial polyp formation in postmenopausal patients and detected inflammatory pathology of the pelvic organs, diseases of the cardiovascular system and fat metabolism disorders. …”
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