Relationship Between YWHAQ Expression and Clinicopathological Features and Prognosis of Patients with Gastric Adenocarcinoma by Xueqing LIU, Libo YANG, Linhai LI, Ping SHENG, Sicheng LIU, Lihua LI

“…Immunohistochemistry was used to detect the protein expression of YWHAQ in gastric adenocarcinoma tissues. …”
Get full text

Statistical Comparison between Pores and Sunspots during the Time Interval 2010–2023 by Yang Peng, Yu Fei, Nan-bin Xiang, Lin-hua Deng, Ting-ting Xu, Sheng Zheng, Shu-guang Zeng, Hai-yang Zhang, Shi-hu Liu

“…The OTSU method and region-growing algorithm were combined to detect umbrae of 11,876 sunspots covering solar cycles 24 and 25. …”
Get full text

Integrative modeling of the spread of serious infectious diseases and corresponding wastewater dynamics by Nina Schmid, Julia Bicker, Andreas F. Hofmann, Karina Wallrafen-Sam, David Kerkmann, Andreas Wieser, Martin J. Kühn, Jan Hasenauer

“…Wastewater-based surveillance offers a promising alternative by detecting viral concentrations from fecal shedding, potentially providing a more accurate estimate of true infection prevalence. …”
Get full text

Qualitative Analysis of Micro-System-Level Factors Determining Sport Persistence by Bence Tamás Selejó Joó, Hanna Czipa, Regina Bódi, Zsuzsa Lupócz, Rozália Paronai, Benedek Tibor Tóth, Hanna Léna Tóth, Oszkár Csaba Kocsner, Buda Lovas, Csanád Lukácsi, Mátyás Kovács, Karolina Eszter Kovács

“…It refers to our attempts concerning the performance plateau, failures, injuries, or even the resolution and processing of stressful situations associated with success and positive events. …”
Get full text

Cell cycle networks link gene expression dysregulation, mutation, and brain maldevelopment in autistic toddlers by Tiziano Pramparo, Michael V Lombardo, Kathleen Campbell, Cynthia Carter Barnes, Steven Marinero, Stephanie Solso, Julia Young, Maisi Mayo, Anders Dale, Clelia Ahrens‐Barbeau, Sarah S Murray, Linda Lopez, Nathan Lewis, Karen Pierce, Eric Courchesne

“…Cell cycle networks detected in blood are highly preserved in the human brain and are upregulated during prenatal states of development. …”
Get full text

Isolation of a tumor neoantigen specific CD8+ TCR from a skin biopsy of a vaccination site by Maria Paula Roberti, Pornpimol Charoentong, Yanhong Lyu, Marten Meyer, Stefan B. Eichmüller, Patrick Schmidt, Frank Momburg, Miray Cetin, Felix Hartmann, Nektarios A. Valous, Albrecht Stenzinger, Laura Michel, Peter Lichter, Andreas Schneeweiss, Verena Thewes, Carlo Fremd, Inka Zörnig, Dirk Jäger

“…Cutaneous biopsies were processed after the fifth vaccination cycle to obtain infiltrating lymphocytes from the vaccination site (VILs). …”
Get full text

Intersection of Cardio‐Oncology: An Overview of Radiation‐Induced Heart Disease in the Context of Tumors by Chunan Zhao, Shuai Xu, Yanru Yang, Xing Shen, Jingjing Wang, Shuang Xing, Zuyin Yu

“…In conclusion, RIHD is a multifaceted disease involving complex biological processes and signaling pathways. Early intervention and targeted therapies are crucial for improving patient outcomes. …”
Get full text

Impaired membrane lipids in ischemic stroke: a key player in inflammation and thrombosis by Qian Wang, Dandan Wang, Yan Gao, Jie Jiang, Minghui Li, Shuhui Li, Xiaowen Hu, Jinfeng Wang, Tianqi Wang, Juan Zhang, Lei Feng, Chao Quan, Ping Zhang, Lan Zheng, Chunling Wan

“…Conclusion Our findings reveal impaired erythrocyte membrane lipid homeostasis in IS, which implicates inflammatory processes and thrombosis in IS. This research offers new insights into the role of membrane lipids in IS pathogenesis, potentially informing future monitoring and therapeutic strategies.…”
Get full text

Diagnostic Applications of AI in Sports: A Comprehensive Review of Injury Risk Prediction Methods by Carmina Liana Musat, Claudiu Mereuta, Aurel Nechita, Dana Tutunaru, Andreea Elena Voipan, Daniel Voipan, Elena Mereuta, Tudor Vladimir Gurau, Gabriela Gurău, Luiza Camelia Nechita

“…By exploring the application of machine learning (ML) and deep learning (DL) techniques, such as random forests (RFs), convolutional neural networks (CNNs), and artificial neural networks (ANNs), this review highlights AI’s ability to analyze complex datasets, detect patterns, and generate predictive insights that enhance injury prevention strategies. …”
Get full text

Genome-Wide Identification and Characterization of SNPs and InDels of <i>Capsicum annuum</i> var. <i>glabriusculum</i> from Mexico Based on Whole Genome Sequencing by Valeria Itzel Moreno-Contreras, Ma. Carmen E. Delgado-Gardea, Jesús A. Ramos-Hernández, Alfonso Mendez-Tenorio, Hugo Varela-Rodríguez, Blanca Sánchez-Ramírez, Zilia Y. Muñoz-Ramírez, Rocío Infante-Ramírez

“…A total of 210,324 variants were detected in CHMX_Ch1, whereas 169,718 variants were identified in QO, all compared to the domesticated <i>C. annuum</i> reference genome, UCD10Xv1.1. …”
Get full text

High Connectivity at Abyssal Depths: Genomic and Proteomic Insights Into Population Structure of the Pan‐Atlantic Deep‐Sea Bivalve Ledella ultima (E. A. Smith, 1885) by Jenny Neuhaus, Mark E. deWilt, Sven Rossel, Saskia Brix, Ron J. Etter, Robert M. Jennings, Katrin Linse, Pedro Martínez Arbizu, Martin Schwentner, Janna Peters

“…ABSTRACT Phylogeographic analyses have advanced our understanding of evolutionary processes in the deep sea, yet patterns of genetic variation and population divergence at abyssal depths remain poorly understood. …”
Get full text

Genomic context determines the effect of DNA methylation on gene expression in the gut epithelium of Atlantic salmon (Salmo salar) by Aikaterini Katirtzoglou, Søren B. Hansen, Harald Sveier, Michael D. Martin, Jaelle C. Brealey, Morten T. Limborg

“…The 21 genes showing significant methylation-expression correlations were involved in biological processes related to salmon health, such as growth and immune responses. …”
Get full text

Where to Protect? Spatial Ecology and Conservation Prioritization of the Persian Squirrel at the Westernmost Edge of Its Distribution by Yiannis G. Zevgolis, Alexandros D. Kouris, Apostolos Christopoulos, Marios Leros, Maria Loupou, Dimitra-Lida Rammou, Dionisios Youlatos, Andreas Y. Troumbis

“…Using a randomized grid-based survey, we recorded 424 presence records across the island and applied a suite of spatial analyses, including Kernel Density Estimation, Getis-Ord Gi*, and Anselin Local Moran’s I, to detect hotspots, coldspots, and spatial outliers. …”
Get full text

Learning to Train and to Explain a Deep Survival Model with Large-Scale Ovarian Cancer Transcriptomic Data by Elena Spirina Menand, Manon De Vries-Brilland, Leslie Tessier, Jonathan Dauvé, Mario Campone, Véronique Verrièle, Nisrine Jrad, Jean-Marie Marion, Pierre Chauvet, Christophe Passot, Alain Morel

“…Despite deceptive generalization capabilities, we demonstrated how our model can be interpreted to uncover biological processes associated with survival. We calculated the contributions of the input genes to the output of the best trained model and derived the corresponding molecular pathways. …”
Get full text

Multimodal sequencing of neoadjuvant nivolumab treatment in hepatocellular carcinoma reveals cellular and molecular immune landscape for drug response by Fanhong Zeng, Qingyang Zhang, Yu-Man Tsui, Huanhuan Ma, Lu Tian, Abdullah Husain, Jingyi Lu, Joyce Man-Fong Lee, Vanilla Xin Zhang, Po-Man Li, Gary Cheuk-Hang Cheung, Tan-To Cheung, Daniel Wai-Hung Ho, Irene Oi-Lin Ng

“…We observed a significantly higher clonal expansion of T cells in the tumors of patients who responded to the treatment, while lipid accumulation was detected in those of non-responders, likely due to inherent differences in lipid metabolic processes. …”
Get full text

GFP fusions of Sec-routed extracellular proteins in Staphylococcus aureus reveal surface-associated coagulase in biofilms by Dominique C. S. Evans, Amanda B. Khamas, Lisbeth Marcussen, Kristian S. Rasmussen, Janne K. Klitgaard, Birgitte H. Kallipolitis, Janni Nielsen, Daniel E. Otzen, Mark C. Leake, Rikke L. Meyer

“…However, our understanding of these processes is limited by challenges of using fluores-cent protein reporters in their native environment, because they must be ex-ported and fold correctly to become fluorescent. …”
Get full text

Insights into the Antimicrobial Mechanisms of a Scorpion Defensin on <i>Staphylococcus aureus</i> Using Transcriptomic and Proteomic Analyses by Xuhua Yang, Haozhen Zhang, Sijia Lu, Yiyuan Guo, Yitong Li, Chenhu Qin, Zheng Zuo, Yingliang Wu, Zhijian Cao

“…Furthermore, glycolysis and other metabolic processes in <i>S. aureus</i> were markedly reduced by BmKDfsin4. …”
Get full text

Small-world network properties and cortical responses of Tai Chi Yunshou: Insights from fNIRS by Jin Fan, Ruijun He, Dongling Zhong, Xiaobo Liu, Huan Liu, Zhi Chen, Qinjian Dong, Yuxi Li, Chen Xue, Jiaming Zhang, Cheng Xie, XianJun Xiao, Xiaoshen Hu, Xi Wu, Juan Li, Rongjiang Jin

“…Results: Small-world network properties (γ>1 and λ≈1) across four states were detected. Compared to states of rest and observation, the motion state exhibited significantly higher γ, λ, Cp, and Eloc (P < 0.01). …”
Get full text

Endogenous plasma resuspension of peripheral blood mononuclear cells prevents preparative-associated stress that modifies polyA-enriched RNA responses to subsequent acute stressors by Dongyang Li, Karina Al-Dahleh, Daniel A Murphy, Sonya Georgieva, Nik Matthews, Claire L Shovlin

“…Human peripheral blood mononuclear cells (PBMCs) are used to examine biological processes and disease, when basal variability in cellular activation and splicing is described and unexplained. …”
Get full text

Anhedonia in the structure of post-COVID syndrome in psychiatric inpatients: the probable role of obesity, systemic inflammation, vascular disregulation and general therapeutic com... by N. B. Lutova, N.. G. Neznanov, A. V. Shabelnik, E. S. Gerasimchuk, M. O. Bocharova, M. Yu. Sorokin

“…Physical anhedonia was detected using the Russian-language version of the Revised physical anhedonia scale (RPAS). …”
Get full text