Characterization of radiation electrophysiological properties of U87 cells induced by ionizing radiation and STAT3 inhibitors under microelectrode matrix sensor by Weijia Fu, Lihua Dong, Yan Gao, Kexin Chen, Qi Huang, Xue Hou, Xueying Bao, Wei Hou, Siyi Hu

“…Method: A cellular electrical impedance–sensing system, including host software and a hardware system consisting of 29 microelectrode arrays, was constructed by us. After group processing, U87 cells were inoculated onto the electrode chips, and changes in the electrical impedance of each group of cells were monitored in real-time. …”
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A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro by Paolo Petazzi, Telma Ventura, Francesca Paola Luongo, Heather McClafferty, Alisha May, Helen Alice Taylor, Michael J Shipston, Nicola Romanò, Lesley M Forrester, Pablo Menendez, Antonella Fidanza

“…As well as providing fundamental new insights into the mechanisms of haematopoietic differentiation, the broader applicability of iCRISPRa provides a valuable tool for studying dynamic processes in development and for recapitulating abnormal phenotypes characterised by ectopic activation of specific endogenous gene expression in a wide range of systems.…”
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A high-performance fluorescent sensor spatiotemporally reveals cell-type specific regulation of intracellular adenosine in vivo by Qingpeng Wei, Zexiao Bai, Lei Wang, Jing Wang, Yipan Wang, Yufei Hu, Shiyi Ding, Zhixiong Ma, Chun Li, Yumo Li, Yizhou Zhuo, Wenzhe Li, Fei Deng, Bingjie Liu, Pengcheng Zhou, Yulong Li, Zhaofa Wu, Jing Wang

“…Abstract Adenosine (Ado), a nucleoside bridging intracellular metabolism with intercellular communication, plays an essential role in regulating processes such as sleep and seizure. While the functions of extracellular Ado (“eAdo”) are well documented, our knowledge about the distribution and regulatory functions of intracellular Ado (“iAdo”) is limited by a lack of methods for detecting iAdo in vivo. …”
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Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. by Suzanne Vogelezang, Jonathan P Bradfield, Tarunveer S Ahluwalia, John A Curtin, Timo A Lakka, Niels Grarup, Markus Scholz, Peter J van der Most, Claire Monnereau, Evie Stergiakouli, Anni Heiskala, Momoko Horikoshi, Iryna O Fedko, Natalia Vilor-Tejedor, Diana L Cousminer, Marie Standl, Carol A Wang, Jorma Viikari, Frank Geller, Carmen Íñiguez, Niina Pitkänen, Alessandra Chesi, Jonas Bacelis, Loic Yengo, Maties Torrent, Ioanna Ntalla, Øyvind Helgeland, Saskia Selzam, Judith M Vonk, Mohammed H Zafarmand, Barbara Heude, Ismaa Sadaf Farooqi, Akram Alyass, Robin N Beaumont, Christian T Have, Peter Rzehak, Jose Ramon Bilbao, Theresia M Schnurr, Inês Barroso, Klaus Bønnelykke, Lawrence J Beilin, Lisbeth Carstensen, Marie-Aline Charles, Bo Chawes, Karine Clément, Ricardo Closa-Monasterolo, Adnan Custovic, Johan G Eriksson, Joaquin Escribano, Maria Groen-Blokhuis, Veit Grote, Dariusz Gruszfeld, Hakon Hakonarson, Torben Hansen, Andrew T Hattersley, Mette Hollensted, Jouke-Jan Hottenga, Elina Hyppönen, Stefan Johansson, Raimo Joro, Mika Kähönen, Ville Karhunen, Wieland Kiess, Bridget A Knight, Berthold Koletzko, Andreas Kühnapfel, Kathrin Landgraf, Jean-Paul Langhendries, Terho Lehtimäki, Jaakko T Leinonen, Aihuali Li, Virpi Lindi, Estelle Lowry, Mariona Bustamante, Carolina Medina-Gomez, Mads Melbye, Kim F Michaelsen, Camilla S Morgen, Trevor A Mori, Tenna R H Nielsen, Harri Niinikoski, Albertine J Oldehinkel, Katja Pahkala, Kalliope Panoutsopoulou, Oluf Pedersen, Craig E Pennell, Christine Power, Sijmen A Reijneveld, Fernando Rivadeneira, Angela Simpson, Peter D Sly, Jakob Stokholm, Kook K Teo, Elisabeth Thiering, Nicholas J Timpson, André G Uitterlinden, Catharina E M van Beijsterveldt, Barbera D C van Schaik, Marc Vaudel, Elvira Verduci, Rebecca K Vinding, Mandy Vogel, Eleftheria Zeggini, Sylvain Sebert, Mads V Lind, Christopher D Brown, Loreto Santa-Marina, Eva Reischl, Christine Frithioff-Bøjsøe, David Meyre, Eleanor Wheeler, Ken Ong, Ellen A Nohr, Tanja G M Vrijkotte, Gerard H Koppelman, Robert Plomin, Pål R Njølstad, George D Dedoussis, Philippe Froguel, Thorkild I A Sørensen, Bo Jacobsson, Rachel M Freathy, Babette S Zemel, Olli Raitakari, Martine Vrijheid, Bjarke Feenstra, Leo-Pekka Lyytikäinen, Harold Snieder, Holger Kirsten, Patrick G Holt, Joachim Heinrich, Elisabeth Widén, Jordi Sunyer, Dorret I Boomsma, Marjo-Riitta Järvelin, Antje Körner, George Davey Smith, Jens-Christian Holm, Mustafa Atalay, Clare Murray, Hans Bisgaard, Mark I McCarthy, Early Growth Genetics Consortium, Vincent W V Jaddoe, Struan F A Grant, Janine F Felix

“…Our results suggest that the biological processes underlying childhood BMI largely, but not completely, overlap with those underlying adult BMI. …”
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Steganography in IoT: A Comprehensive Survey on Approaches, Challenges, and Future Directions by Maha Driss, Lamia Berriche, Safa Ben Atitallah, Siwar Rekik

“…We evaluated and validated the techniques employed using key metrics such as imperceptibility, robustness, and embedding capacity while emphasizing the computational restrictions, real-time processing requirements of IoT devices, and the vital requirement for energy-efficient algorithms. …”
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Image-based soft drink type classification and dietary assessment system using deep convolutional neural network with transfer learning by Rubaiya Hafiz, Mohammad Reduanul Haque, Aniruddha Rakshit, Mohammad Shorif Uddin

“…The experiment confirms that our system can detect and recognize different types of drinks with an accuracy of 98.51%.…”
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Metagenomics Insights into the Role of Microbial Communities in Mycotoxin Accumulation During Maize Ripening and Storage by Xuheng Nie, Xuefeng Chen, Xianli Lu, Shuiyan Yang, Xin Wang, Fuying Liu, Jin Yang, Ying Guo, Huirong Shi, Hui Xu, Xiang Zhang, Maoliang Fang, Yin Tao, Chao Liu

“…Among 32,333 annotated KEGG pathways, primary metabolic processes predominated (43.99%), while glycoside hydrolases (GH) and glycosyltransferases (GT) constituted 76.67% of the 40,202 carbohydrate-active enzymes. …”
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Characterization of antibiotic resistance genes in soils from agroecosystems of the Brazilian Amazon by Taynara Cristina Santos Tavares, Lívia Freitas da Silva Pinto, Oscar Victor Cardenas-Alegria, Carlos William Dias Dantas, Sandro Patroca da Silva, Ana Cecília Ribeiro Cruz, Aníbal Coutinho do Rêgo, Hervé Louis Ghislain Rogez, Rommel Thiago Juca Ramos, Cristian Faturi, Adriana Ribeiro Carneiro Nunes

“…The samples underwent processing to extract genetic material and were sequenced using the Illumina platform. …”
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Changes in cold-pressed oil due to roasting of hazelnut kernels by Radovanović Mirjana, Kurtić Jelena, Petković Marko, Miletić Nemanja, Đurović Vesna

“…Roasting the kernels had no effect on the content of water and volatile matter. No peroxides were detected either, regardless of whether the kernels were subjected to heat treatment. …”
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Evaluation of a Natural Olive Extract as a Flavor Component in Dry and Wet Dog Foods by Ryan Guldenpfennig, Clare Hsu, Krysten Fries-Craft, Adriana Garber, Xinhe Huang, Mark Wieneke, Kristen Rutledge

“…Flavor compounds in OE were analyzed by gas chromatography–mass spectrometry and high-pressure liquid chromatography, detecting 137 volatile compounds, including acetic acid and hydroxytyrosol. …”
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An objective neurophysiological study of subconcussion in female and male high school student athletes by Ryan C. N. D’Arcy, David McCarthy, Derek Harrison, Zander Levenberg, Julian Wan, Aidan Hepburn, Eric D. Kirby, Tanja Yardley, Nikita Yamada-Bagg, Shaun D. Fickling, Thayne A. Munce, David W. Dodick, Christopher Ahmad, Ken Shubin Stein

“…The findings demonstrated that subconcussive impairments are detectable in a controlled experimental comparison for both female and male high school athletes. …”
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Analysis and validation of serum biomarkers in brucellosis patients through proteomics and bioinformatics by Xiao Li, Bo Wang, Xiaocong Li, Juan He, Yue Shi, Rui Wang, Dongwei Li, Ding Haitao, Ding Haitao

“…After ELISA validation, five proteins were ultimately selected.DiscussionThese five proteins are implicated in the innate immune processes of brucellosis, potentially associated with its pathogenic mechanisms and chronicity. …”
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Mass Transfer in Eccentric Black Hole–Neutron Star Mergers by Yossef Zenati, Mor Rozner, Julian H. Krolik, Elias R. Most

“…The mass transfer creates a gas disk around the black hole before merger that can be comparable in mass to the debris remaining after merger, i.e., ~0.1 M _⊙ . These processes are most important when the initial neutron star–black hole mass ratio q is in the range ≈0.2–0.8, the orbital semimajor axis is 40 ≲  a _0 / r _g  ≲ 300 ( r _g  ≡  GM _BH / c ^2 ), and the eccentricity is large at e _0  ≳ 0.8. …”
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Longitudinal relationships between serum ferritin and prognosis among severe community-acquired pneumonia patients by Jing Xu, Jing Xu, Ming-Feng Han, Ming-Feng Han, Kai-Shu Ma, Ting Zhang, Ting Zhang, Rui-Rui Wang, Rui-Rui Wang, Jing-Jing Zhang, Jing-Jing Zhang, Hui Zhao, Hui Zhao, Lin Fu, Lin Fu

“…BackgroundFerritin is one of the major intracellular iron storage proteins and is implicated in the pathophysiological processes of many inflammatory diseases, but its function in community-acquired pneumonia (CAP) was unclear. …”
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A Hidden Pulse: Uncovering a New Timing Signal in Cygnus X-1 with AstroSat by Sandeep K. Rout, Federico García, Mariano Méndez, Abhay Kumar, Santosh Vadawale, David M. Russell, Pei Jin

“…The study of fast variability properties in X-ray binaries advances our understanding of the physical processes and geometric properties of the accretion flow around the compact object. …”
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Rare Phosphides and Nitrides in Igneous Clasts within Aqueously Altered Chondrites by Lucas. R. Smith, Pierre Haenecour, Jessica J. Barnes, Kenneth Domanik, Yao-Jen Chang, Dolores Hill

“…Chondritic meteorites and their components provide us with the means to investigate the conditions and processes in the early solar system, including the delivery of bio-essential elements, such as phosphorus, to the early Earth. …”
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Identification of active gully erosion sites on the loess plateau based on terrain profile lines by Shan He, Jilong Li, Han Wu, Tianjiao Cui

“…We first generated gully topographic profiles in the Zhifang Catchment (Ansai District) through DEM processing using the multiple-flow-direction (MFD) algorithm. …”
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Classifying vocal responses of broilers to environmental stressors via artificial neural network by T. Lev-ron, Y. Yitzhaky, I. Halachmi, S. Druyan

“…Detecting early-stage stress in broiler farms is crucial for optimising growth rates and animal well-being. …”
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Predictor Importance for Hydrological Fluxes of Global Hydrological and Land Surface Models by João Paulo L. F. Brêda, Lieke A. Melsen, Ioannis Athanasiadis, Albert VanDijk, Vinícius A. Siqueira, Anne Verhoef, Yijian Zeng, Martine van derPloeg

“…We propose a model diagnostic approach based on Random Forest (RF) feature importance to detect the input variables that most influence simulated hydrological fluxes. …”
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Associations between cardiometabolic indices and heart disease among elderly and middle-aged Chinese individuals: a retrospective longitudinal study by Ya Li, Li Jiao, Wei Chen, Xue-Feng Ni, Wen Zhang, Shu-Yang Zhang

“…This index is useful for detecting metabolic diseases as well as some cardiovascular diseases. …”
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