Our experience with pectoralis major flap for management of sternal dehiscence: A review of 25 cases by Parag Sahasrabudhe, Ranjeet Jagtap, Pankaj Waykole, Nikhil Panse, Pallavi Bhargava, Sampada Patwardhan

“…Conclusions: The double breasting technique of the pectoralis major muscle flaps with rectus sheath extension is efficient in covering the entire length of the defect and can reduce the morbidity, without affecting the function of the shoulder joint.…”
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Amniotic Membrane Transplantation in Surgical Treatment of Conjunctival Melanoma: Long-term Results by Melis Palamar, Banu Yaman, Taner Akalın, Ayse Yağcı

“…Complications and tumor control rates were evaluated. Results: The mean age of the patients was 57.4±15.2 (range, 37-84) years. …”
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Combinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing's Sarcoma. by Sonja J Gill, Jon Travers, Irina Pshenichnaya, Fiona A Kogera, Syd Barthorpe, Tatiana Mironenko, Laura Richardson, Cyril H Benes, Michael R Stratton, Ultan McDermott, Stephen P Jackson, Mathew J Garnett

“…Here, we show that PARP inhibitor sensitivity in Ewing's sarcoma cells is not through an apparent defect in DNA repair by HR, but through hypersensitivity to trapped PARP1-DNA complexes. …”
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STUDY ON MECHANICAL PROPERTIES OF POROUS SCAFFOLD AND DESIGNING OF MANDIBULAR PROSTHESIS BASED ON SLM FORMING by YAN HanSheng, WEI Bo, LIU Chris, QIU YongLiang

“…The tissue engineered bone provides an important method for repairing large segmental bone defects.However,how to design a prosthesis that matches the mechanical properties of host bone remains to be studied.Therefore,this study aimed to explore the scaffold mechanical properties based on selective laser melting(SLM)fonning printing technology for scaffold and apply to mandibular reconstruction.Firstly,hexahedral(HE),octahedral(OC)and body centred cubic(BCC)unit cell porous scaffolds with different porosity(50%-80%)were established,and the porous scaffold mechanical properties were analyzed by finite element analysis.Secondly,the porous Ti6Al4V scaffolds with strong mechanical properties were prepared by SLM forming technology,and the scaffold mechanical properties were evaluated by the compression test.Finally,the least square method was used to fit the scaffold porosity⁃elastic modulus curve,so as to obtain the porous prosthesis with mechanical properties matching the mandibular defect region.The results show that the maximum stress of porous scaffold increases with the increase of porosity and is closely related to the configuration(BCC>OC>HE).The compression test shows that the scaffold elastic modulus with different porosities is significantly different,and the porosity is inversely proportional to the elastic modulus.According to the Gibson⁃Ashby model of hexahedral unit cell scaffold,the ideal prosthesis porosity is 53.1%.Additionally,the safety of the prosthesis is verified by finite element analysis.The finite element analysis and compression test confirmed that the scaffold mechanical properties with different porosities are discrepant,and the optimized prosthesis with appropriate porosity can better match the mechanical properties of host bone,which provides valuable insights for implant design.…”
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A Multimodel Decision Fusion Method Based on DCNN-IDST for Fault Diagnosis of Rolling Bearing by Weixiao Xu, Luyang Jing, Jiwen Tan, Lianchen Dou

“…To solve the above problems, a multimodel decision fusion method based on Deep Convolutional Neural Network and Improved Dempster-Shafer Evidence Theory (DCNN-IDST) is proposed for the inspection of rolling bearing. To solve the defect of the original evidence theory method in the fusion of high-conflict evidence, the fuzzy consistency matrix is introduced. …”
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A Clinical, Neuropathological and Genetic Study of Homozygous A467T POLG-Related Mitochondrial Disease. by Sanjeev Rajakulendran, Robert D S Pitceathly, Jan-Willem Taanman, Harry Costello, Mary G Sweeney, Cathy E Woodward, Zane Jaunmuktane, Janice L Holton, Thomas S Jacques, Brian N Harding, Carl Fratter, Michael G Hanna, Shamima Rahman

“…The mechanism by which this single genetic defect results in such clinical diversity remains unclear. …”
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Hybrid coating prepared with PMMA/Ti-O-Si tested under vacuum conditions for use in nanosatellites. by Bryanda G Reyes-Tesillo, Genoveva Hernández-Padrón, Jorge A Ferrer-Pérez, Alfredo Maciel-Cerda

“…To evaluate its resistance to ultra-high vacuum, it was done as close as possible to the ASTM E-595 norm [1], where it indicates that the coatings must be evaluated at vacuum conditions of 10-5 Torr and 125°C for a period of 24 hours. …”
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Stability-Enhanced Ternary Solid Dispersions of Glyburide: Effect of Preparation Method on Physicochemical Properties by Leila Barghi, Afshin Vekalati, Azin Jahangiri

“…Despite their efficiency, drug crystallization tendency and poor physical stability limited their commercial use. To overcome this defect, ternary solid dispersions of glyburide: sodium lauryl sulfate (SLS) and polyethylene glycol 4000 (PEG), were developed using the fusion (F) and solvent evaporation (SE) techniques and subsequently evaluated and compared. …”
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Posterior Dynamic Stabilization with Limited Rediscectomy for Recurrent Lumbar Disc Herniation by Lei Luo, Chen Zhao, Pei Li, Liehua Liu, Qiang Zhou, Fei Luo, Lichuan Liang

“…Moreover, it could maintain disc height and decrease the risk of recurrence in patients with a large posterior annular defect.…”
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A multi-centre, participant-blinded, randomized, 3-year study to compare the efficacy of Virtual Surgical Planning (VSP) to Freehand Surgery (FHS) on bony union and quality of life... by Khanh Linh Tran, Sena Turkdogan, Anat Bahat Dinur, Thomas D. Milner, Edward Wang, Anthony Nichols, Danielle MacNeil, Adrian Mendez, Jake Jervis-Bardy, John De Almeida, Christopher Yao, David Goldstein, Ralph Gilbert, Antoine Eskander, Kevin Higgins, Danny Enepekides, Michael Gupta, Han Zhang, Michael Au, Sally Nguyen, Sidney Fels, Antony Hodgson, Penelope Brasher, Craig Mitton, Farahna Sabiq, Charles Fisher, David Yang, Angela Wong, Cathie Garnis, Catherine Poh, J. Scott Durham, Eitan Prisman

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Saliva-derived exosomes regulate fibroblast metabolic reprogramming in skin wound healing by Sijia Song, Sijia Song, Sijia Song, Sijia Song, Rong Xiang, Rong Xiang, Rong Xiang, Rong Xiang, Siyu Chen, Siyu Chen, Siyu Chen, Siyu Chen, Jianbo Wu, Jianbo Wu, Jianbo Wu, Jianbo Wu, Wenxia Chen, Wenxia Chen, Wenxia Chen, Wenxia Chen, Xianyu Li, Xianyu Li, Xianyu Li, Xianyu Li

“…A rat full-thickness skin defect model and in vitro assays with human skin fibroblasts and HaCaT keratinocytes were employed to evaluate S-Exo effects on wound closure, ECM remodeling, and cellular metabolism. …”
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Real-Time Explainable Multiclass Object Detection for Quality Assessment in 2-Dimensional Radiography Images by Sadra Naddaf-Sh, M-Mahdi Naddaf-Sh, Hassan Zargarzadeh, Maxim Dalton, Soodabeh Ramezani, Gabriel Elpers, Vinay S. Baburao, Amir R. Kashani

“…Quality inspection and defect detection play a critical role in infrastructure safety and integrity specially when it comes to aging infrastructure mostly owned by governments around the world. …”
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Diagnostics of structural integrity violations of avionics during impact tests by S. U. Uvaysov, A. V. Dolmatov, The H. Vo, Ngoc T. Luu, Cong D. Nguyen

“…Based on known methods, a new diagnostic method is proposed which simulates mechanical processes under shock effects at the design stage. The aim is to evaluate the presence of various latent defects in SAU. …”
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Keystone flaps in coloured skin: Flap technology for the masses? by Satish P Bhat

“…Materials and Methods: This retrospective review involves 55 consecutive Keystone flaps used from 2009 to 2012, for skin defects in various locations. Patient demographic data, medical history, co-morbidity, surgical indication, defect features, complications, and clinical outcomes are evaluated and presented. …”
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UAV-Based Structural Health Monitoring Using a Two-Stage CNN Model with Lighthouse Localization in GNSS-Denied Environments by Timothy Scott C. Chu, Joses Sorilla, Alvin Y. Chua

“…Future work includes expanding the dataset, generalization, and evaluating scalability via multi-base station setups. …”
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Comparative analysis of the open and the arthroscopic Latarjet procedure by M. L. Holovakha, O. V. Shchokin, B. A. Kuznietsov

“…Latarjet procedure is one of the relevant surgical techniques for the anterior and antero-inferior type of recurrent instability in the shoulder joint with a defect in the articular surface of the glenoid. …”
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Development of human hepatocellular carcinoma in X-linked severe combined immunodeficient pigs: An orthotopic xenograft model. by Kohei Mishima, Osamu Itano, Sachiko Matsuda, Shunichi Suzuki, Akira Onishi, Masashi Tamura, Masanori Inoue, Yuta Abe, Hiroshi Yagi, Taizo Hibi, Minoru Kitago, Masahiro Shinoda, Yuko Kitagawa

“…Tumor engraftment was evaluated weekly using ultrasonography, and cone-beam computed tomography was performed during arterial portography (CTAP) and hepatic arteriography (CTHA) to evaluate the hemodynamics of engrafted tumors. …”
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Novel SUN5 Mutation Associated with Acephalic Spermatozoa Syndrome: A Cross-sectional Study by Sarvenaz Alinia, Fatemeh Eskandari Chenari, Seyedeh-Hanieh Hosseini, Alemeh Rafaee, Amaneh Javid, Mohammad Ali Sadighi Gilani, Marjan Sabbaghian

“…The SUN5 gene has an established role in the acephalic spermatozoa syndrome (ASS) defect recognised by headless tails, spermatozoa with disrupted head–tail junction and also a few tailless heads in semen. …”
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A Poly-γ-Glutamic Acid/ε-Polylysine Hydrogel: Synthesis, Characterization, and Its Role in Accelerated Wound Healing by Jiaqi Li, Yuanli Huang, Yalu Wang, Qianqian Han

“…Its physicochemical properties, including rheological behavior and swelling capacity, were systematically evaluated. Biocompatibility was assessed via in vitro hemolysis and cytotoxicity assays, and in vivo testing was performed using a full-thickness skin defect model in Sprague Dawley (SD) rats to evaluate wound-healing efficacy. …”
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Step-Ladder Expansive Cranioplasty after Decompressive Craniotomy and Expansive Duraplasty: Discussing Possibilities on a Mathematical Model by S. K. Sengupta

“…Based on the calculations on the model, it was found that a projection of dural outpouching of 0.83 cm beyond the craniectomy margin on either side of a bilateral 12 × 15 cm elliptical craniectomy defect is required to achieve and accommodate a volume expansion of 157 cm3, which was recorded to be the maximum volume expansion in the reviewed literature. …”
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