Sea buckthorn-derived extracellular vesicles foster bone regeneration through aau-miR168-mediated pathways by Mai Zhao, Xiaolin Chen, Wenyan Wang, Mengying Li, Hui Zhang, Xiuqun Zou, Jiamin Wang, Qian Cong, Xingyuan Ma, Zhaoyuan Hou, Haodong Lin, Hao Jia

“…Bone marrow mesenchymal stromal cells (BMSCs) were treated with SAEVs, and cellular uptake was evaluated through fluorescence microscopy and flow cytometry. …”
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TCF7L2 regulates GPX4 to resist ferroptosis and enhance osteogenesis in mouse mesenchymal stem cells by Ming Lei, Boyu Liu, Baicheng Wan, Yanbin Feng, Yilin Teng, Deshuang Xi, Gaofeng Zeng, Shaohui Zong

“…Abstract Critical-sized bone defects, characterized by poor spontaneous healing capacity, remain a common clinical challenge, and stem cell and gene therapies are key strategies for bone repair and regeneration. …”
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Experimental orthotopic implantation of tissue-engineered tracheal graft created based on devitalized scaffold seeded with mesenchymal and epithelial cells by M. V. Balyasin, D. S. Baranovsky, A. G. Demchenko, A. L. Fayzullin, O. A. Krasilnikova, I. D. Klabukov, M. E. Krasheninnikov, A. V. Lyundup, V. D. Parshin

“…Results were evaluated by computed tomography, histological and immunohistochemical analyzes. …”
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Effectiveness of Vancomycin-Impregnated Bone Graft Substitutes for the Treatment of Chronic Osteomyelitis in Long Bones: Comparative Analysis by Alexander P. Antipov, Svetlana A. Bozhkova, Ekaterina M. Gordina, Alexander V. Afanasyev, Magomed S. Gadzhimagomedov

“…Background. Replacement of bone defects in the surgical treatment of chronic osteomyelitis is a key step to prevent recurrence of infection and potential fractures at the site of rehabilitation. …”
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One‐year follow‐up after standardized perineal reconstruction in women with deficient perineum after vaginal delivery by Emilia Rotstein, Vilhelmina Ullemar, Hedvig Engberg, Angelica Lindén Hirschberg, Gunilla Ajne, Gunilla Tegerstedt

“…Inclusion criteria were a visible perineal scar and confirmed anatomic defect. Levator ani defects were assessed using the Levator Ani Deficiency score. …”
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Versatility of Vascularized Fibular Graft in Forearm Bone Loss: From Initial Treatment to Secondary Nonunion Treatment by Bruno Battiston, MD, PhD, Francesca Fissore, MD, Elisabetta Mijno, MD, Davide Ciclamini, MD

“…Results: A total of 26 cases were treated with VFG for forearm bone defect reconstruction (13 for primary treatment and 13 for secondary treatment of nonunion). …”
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Magnetic resonance imaging in terms of observation of patients after transanal resections of rectal tumors by S. A. Myalina, T. P. Berezovskaya, A. A. Nevolskikh, V. A. Avdeenko, S. A. Ivanov, A. D. Kaprin

“…The method of MRI can be recommended as the method of choice for assessing the pelvic region after transanal endoscopic microsurgery (TEM), which allows for high accuracy to exclude continued tumor growth; to assess the pelvic region for the presence of distant metastases; to determine the defect of the walls in the excision zone of tumors. …”
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Surgical Treatment of Primary Penetrating Macular Retinal Tears Using an “Effective” Fragment of the Internal Limiting Membrane by A. V. Tereshchenko, N. M. Shilov, N. N. Yudina, Yu. A. Sidorova, E. V. Erokhina, S. V. Novikov, A. N. Mits

“…After 3 months, in 3 patients, the defect of the outer layers of the retina completely disappeared. …”
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Stimulated Human Umbilical Cord Mesenchymal Stem Cells Enhance the Osteogenesis and Cranial Bone Regeneration through IL-32 Mediated P38 Signaling Pathway by Xiaru Zhang, Ying Zheng, Gang Wang, Yuanlin Liu, Yang Wang, Xueyi Jiang, Yueqing Liang, Xinfeng Zhao, Ping Li, Yi Zhang

“…Moreover, a rat skull bone defect model was established and treated by directly injecting the IL-32highHuMSCs to conduct its role on the cranial bone regeneration. …”
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Supracardiac type of total anomalous pulmonary venous connection: Diagnosis and demonstration by multidetector CT angiography by Neha Singh, MD, Guriya Kumari, MD, Deepak Kumar Singh, MCh

“…Pulmonary venous developmental anomalies have historically been evaluated using echocardiography and catheter-based angiography. …”
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Numerical simulation of a steel weld joint and fracture mechanics study of a Compact Tension Specimen for zones of weld joint by Ahmed Bensari, El Bahri Ould Chikh, Benattou Bouchouicha, Malika Tirenifi

“…We seek then, to show the mechanical resistance for this defect mode. It also seeks to fit the mechanical resistance of a structure in the presence of a crack when the defects have been detected during an inspection. …”
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The influence of decompressive craniectomy on the development of hydrocephalus: a review by Jun Ding, Yan Guo, Hengli Tian

“…Numerous complications may arise after DC, including contusion or hematoma expansion, epilepsy, herniation of the cortex through a bone defect, CSF leakage through the scalp incision, infection, subdural effusion, hydrocephalus and “syndrome of the trephined”. …”
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Aortic atresia with complex aortic arch collateralization through the subclavian arteries by Saumya Kapoor, Thomas Knapp, Peace Madueme, Katherine T. Braley, Peter D. Wearden, Jennifer S. Nelson

“…A term newborn boy was diagnosed with aortic atresia and ventricular septal defect with duplicated subclavian arteries bilaterally. …”
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PREOPERATIVE AND INTRAOPERATIVE RISKS OF ERRORS IN CYSTS SURGERY OF THE BILE DUCTS IN CHILDREN by E. A. Yakubov

“…The data of 76 patients with cystic transformations of the bile duct were evaluated. Various operations were performed on 74 (97,4 %) patients. …”
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Comparison of the clinical effects of reverse digital artery island flap and dorsal branch digital artery island flap on digital tip reconstruction: a single-center retrospective s... by Yue Pan, Jun Lei, Jun Yang, Mingwei Dong, Shengjie Jiang, Guangchen Sun, Hui Yu

“…There were 24 patients in the reverse digital artery island flap group and 17 patients in the dorsal branch digital artery island flap group. The size of the defect area of the affected finger, the range of motion (ROM) of the interphalangeal joint, the operation time, the hospital stay and the cold tolerance were evaluated and compared. …”
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Extraction and Analysis of Influencing Factors of Scientific and Technological Ability Improvement of University Teachers Based on Deep Learning Model by Aiqin Wang, Wei Yan

“…This article analyzes the data of teaching evaluation and finds that the text contains students’ subjective understanding of teachers’ teaching quality defects. …”
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Allergic diseases in children with primary immunodeficiencies by Celal Özcan, Ayşe Metin, Mustafa Erkoçoğlu, Can Naci Kocabaş

“… The aim of this study was to evaluate and compare the frequency of atopy and allergic disease in all groups of primary immunodeficiency (PID) patients. …”
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Understanding the Educational and Social Difficulties in Children with Hemifacial Microsomia – A Literature Review by Michał Pniak, Paweł Miklis, Maciej Mawlichanów, Aleksandra Ciesielska, Aleksandra Sieradzka, Krzysztof Szerej, Zofia Czaplińska-Paszek, Alicja Kot, Marta Wojtczak, Natalia Myśliwiec, Adrian Róźycki

“…Study aims to evaluate the impact of defect on the neurodevelopmental and psychosocial outcomes in affected children.  …”
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Empowering limited-resource countries: collaborating with expert centers for diagnosis of primary ciliary dyskinesia by Mine Yuksel Kalyoncu, Rim Hjeij, Muruvvet Yanaz, Aynur Gulieva, Merve Selcuk Balcı, Şeyda Karabulut, Neval Metin Cakar, Almala Pınar Ergenekon, Ela Erdem Eralp, Yasemin Gokdemir, Heymut Omran, Bülent Taner Karadag

“…One case (5.3%) had cells without cilia, indicating a possible ciliogenesis defect. All individuals with abnormal IF analysis had a PICADAR score of 6 or above, and their cilia were immotile in HSVM.DiscussionConsistent with the IF finding suggesting a ciliogenesis defect, further genetic analysis revealed biallelic pathogenic variants in CCNO in the affected individual. …”
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Extensive scalp soft-tissue reconstruction with free flaps: A simplified therapeutic algorithm for donor site selection based on a retrospective analysis by Raúl Martínez Peral, Josep Oriol Roca Mas, Gonzalo Joaquín Soroa Moreno, Adela Álvarez Río, Antonio Ansó Jiménez, Daniel Navarro Sánchez, Ivan Monge Castresana, Jaime Estrada Cuxart

“…Reconstructive and postoperative data for all patients were collected, evaluated, and compared. Results: The mean defect size to be restored was 110.60 ± 14.55 cm² (LD 162.23 ± 23.1 cm2, OM 141.68 ± 11.80 cm2, ALT 73.83 ± 14.69 cm2, and RFF 37.13 ± 4.88 cm2). …”
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