Analysis of MTHFR 1298A>C in addition to MTHFR 677C>T polymorphism as a risk factor for neural tube defects in the Turkish population by Koray Boduroğlu, Yasemin Alanay, Mehmet Alikaşifoğlu, Dilek Aktaş, Ergül Tunçbilek

“…Many studies have reported significant association between MTHFR 677C>T and increased risk of neural tube defects (NTDs). Our previous study did not support this observation. …”
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Autogenous Bone and Bioactive Glass around Implants Placed Simultaneously with Ridge Splitting for the Treatment of Horizontal Bony Defects: A Randomised Clinical Trial by Walid Elamrousy, Mohamed Osama, Dalia Rasheed Issa

“…To compare using autogenous bone with or without bioactive glass in ridge splitting of horizontal bone defects combined with simultaneous implant placement. …”
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Assessing tree-related microhabitat retention according to a harvest gradient using tree-defect surveys as proxies in Eastern Canadian mixedwood forests by Maxence Martin, Patricia Raymond

“…The objectives of our study were: (1) to demonstrate that defect surveys can be a reliable resource to identify TreMs; and, (2)to evaluate the capacity of silvicultural treatments to maintain TreM abundance and diversity according to a harvest gradient.To achieve these objectives, we identified TreMs from a defect survey performed the year a harvest gradient was applied to20 plots, including uncut control, shelterwood treatments removing 50%, 43% and 36% of basal area, and clearcut (4 plots/treatment). …”
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Multi-Channel Fusion Decision-Making Online Detection Network for Surface Defects in Automotive Pipelines Based on Transfer Learning VGG16 Network by Jian Song, Yingzhong Tian, Xiang Wan

“…Each channel of the network is designed according to the characteristics of different types of defects. Dynamic weights are assigned to achieve decision-level fusion through the use of a matrix of indicators to evaluate the performance of each channel’s recognition ability. …”
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A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP. by April M Weissmiller, Orlangie Natera-Naranjo, Sol M Reyna, Matthew L Pearn, Xiaobei Zhao, Phuong Nguyen, Soan Cheng, Lawrence S B Goldstein, Rudolph E Tanzi, Steven L Wagner, William C Mobley, Chengbiao Wu

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Micro-CT Analysis of Bone Healing in Rabbit Calvarial Critical-Sized Defects with Solid Bioactive Glass, Tricalcium Phosphate Granules or Autogenous Bone by Olli-Pekka Lappalainen, Sakari S. Karhula, Marianne Haapea, Sami Kauppinen, Mikko Finnilä, Simo Saarakkala, Willy Serlo, George K. Sándor

“…Objectives: The purpose of the present study was to evaluate bone healing in rabbit critical-sized calvarial defects using two different synthetic scaffold materials, solid biodegradable bioactive glass and tricalcium phosphate granules alongside solid and particulated autogenous bone grafts. …”
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Reconstruction of experimentally induced radial bone defect in rabbits by using acellular fish swim bladder and autologous bone marrow clot: Histopathological assessment by Noor A. Mahdi, Nadia H. Al-Falahi

“…The bone defects in all groups were evaluated histopathologically at 4,8- and 12-weeks post-operation to observe the bone formation and bridging of segmental bone defects. …”
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Purse string suture for rapid access hemostasis after removal of large-caliber femoral venous delivery sheaths in children with atrial septal defects by Gang Luo, Zhixian Ji, Bei Zhang, Yueyi Ren, Silin Pan

“…Abstract Objectives To evaluate the efficacy and safety of purse-string sutures (PSS) compared with manual compression for access hemostasis in children with atrial septal defects (ASDs) after large-caliber venous delivery sheaths removal. …”
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Alterations in Gut Microbiome Composition and Barrier Function Are Associated with Reproductive and Metabolic Defects in Women with Polycystic Ovary Syndrome (PCOS): A Pilot Study. by Lisa Lindheim, Mina Bashir, Julia Münzker, Christian Trummer, Verena Zachhuber, Bettina Leber, Angela Horvath, Thomas R Pieber, Gregor Gorkiewicz, Vanessa Stadlbauer, Barbara Obermayer-Pietsch

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Effect of treadmill exercise timing on repair of full-thickness defects of articular cartilage by bone-derived mesenchymal stem cells: an experimental investigation in rats. by Jin-qi Song, Fu Dong, Xue Li, Chang-peng Xu, Zhuang Cui, Nan Jiang, Jun-jie Jia, Bin Yu

“…However, optimal timing of moderate exercise is unclear. We aimed to evaluate the effect of timing of moderate treadmill exercise on repair of full-thickness defects of articular cartilage.…”
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Governor Vessel combined with local acupoints electroacupuncture improves the therapeutic effect of nerve conduit transplantation bridging long segment defects of the median nerve by Yu Cheng, Fanqi Meng, Zhanmou Liang, Xin Zhou, Wenya Pei, Jingwen Ruan, Xiaozhou Lu, Ying Ding, Guanheng He

“…All experimental rats were randomly assigned to the following groups: Control, Conduit, Local acupoints electroacupuncture (EA) (Local-EA), and governor vessel (GV) combined with local acupoints electroacupuncture (GV+Local-EA) groups. A 10-mm defect model was established in the left median nerve, and a chitosan nerve conduit was used to bridge the defect. …”
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Comparison between intraperitoneal onlay mesh repair with closure of fascial defect (IPOM plus) and intraperitoneal onlay mesh repair (IPOM) for ventral hernias by H. O. Havrylov, O. V. Shulyarenko, M. O. Yosypenko

“…Aim. To evaluate the intraperitoneal onlay mesh repair with closure of fascial defect (IPOM plus) versus intraperitoneal onlay mesh (IPOM) for ventral hernias (VHs). …”
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The ERBB2 c.1795C>T, p.Arg599Cys variant is associated with left ventricular outflow tract obstruction defects in humans by Minna Ampuja, Sabina Ericsson, Ilkka Paatero, Iftekhar Chowdhury, Jenna Villman, Martin Broberg, Amanda Ramste, Diego Balboa, Tiina Ojala, Jessica X. Chong, Michael J. Bamshad, James R. Priest, Markku Varjosalo, Riikka Kivelä, Emmi Helle

“…The aim of this study was to evaluate the pathogenicity of a heterozygous ERBB2 variant c.1795C>T, p.Arg599Cys identified in three families with LVOTO defects. …”
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Serum biochemical indicators in rats of different ages after replacing femoral metaphysis defects with allogeneic bone implants saturated with mesenchymal stem cells by P. M. Vorontsov, M. O. Korzh, F. S. Leontieva, V. O. Tuliakov

“…The aim of the study: to evaluate the course of metabolic processes after replacing femoral metaphysis defects with allogeneic bone implants saturated with allogeneic mesenchymal stem cells (MSCs) based on the analysis of serum biochemical indicators of connective tissue metabolism in laboratory rats. …”
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Free vascularized fibula transfer in single- or double-barrel technique for reconstruction of segmental bone defects following oncological resection or posttraumatic bone loss by Bienger, Kevin, Stefan, Vlad, Dragu, Adrian, Bota, Olimpiu, Taqatqeh, Feras, Schaser, Klaus-Dieter, Rudari, Michele, Fritzsche, Hagen

“…The utilization of a single- or double-barrel approach, contingent on the defect’s characteristics, optimizes length conservation or enhances the stability of extensive defects.Methods: We retrospectively evaluated patients who underwent the FVFG procedure, employing either a single- or double-barrel technique, at our medical center during the period from August 2017 to May 2023. …”
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USC-Derived Small Extracellular Vesicles-Functionalized Scaffolds Promote Scarless Vaginal Defect Repair via Delivery of Decorin and DUSP3 Proteins by Xu Y, Li J, Qiu Y, Wu F, Xue Z, Liu B, Fan H, Zhou Y, Wu Q

“…The efficacy of sEVs-loaded scaffolds in the treatment of vaginal defects in rabbits was assessed by histological analysis. …”
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Central slip defect reconstruction utilizing partial ulnar side of flexor digitorum superficial tendon for chronic boutonniere deformity: A case report by Andriessanto Ceelvin Lengkong, Albertus Djarot Noersasongko, Haryanto Sunaryo, R. Tommy Suharso, Rangga B.V. Rawung, Stefan A.G.P Kambey, Alfons Datui

“…The patient underwent central slip defect reconstruction utilizing the partial ulnar side of the flexor digitorum superficial tendon. …”
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Proximal humeral endoprosthetic reconstruction for tumour defects: clinical outcomes of 165 patients from the MUTARS Orthopedic Registry Orthopedic Registry Europe (MORE) by Richard Evenhuis, Michaël P. A. Bus, Simen Sellevold, Edwin F Dierselhuis, Ioannis G Trikoupis, Maurizio Scorianz, Sebastian Walter, Jorge Cabrolier, Marta Fiocco, Michiel A. J. van de Sande, MORE study group

“…This study aimed to evaluate clinical and functional outcomes of reconstructions of proximal humeral tumour defects with MUTARS endoprostheses. …”
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Evaluation of Bone Biomarkers in Renal Osteodystrophy by Alinie Pichone, Carlos Perez Gomes, Carolina Aguiar Moreira, Maria Lucia Fleiuss Farias, Maurilo Leite

“…This cross-sectional study evaluates several bone biomarkers and their ability to discriminate turnover and mineralization defects in hemodialysis (HD) patients. …”
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Image Inpainting Methods Evaluation and Improvement by Raluca Vreja, Remus Brad

“…Based on these experiments, we have proposed an adaptation of Oliveira’s and Hadhoud’s algorithms, which are performing well on images with natural defects.…”
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